Published in Appl Bioinformatics on January 01, 2004
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Prediction of amyloidogenic and disordered regions in protein chains. PLoS Comput Biol (2006) 1.58
Chaperone activity of ERD10 and ERD14, two disordered stress-related plant proteins. Plant Physiol (2008) 1.54
Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes. J Virol (2008) 1.53
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Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival. Mol Brain (2009) 1.22
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Substrate-dependent unfolding of the energy coupling motif of a membrane transport protein determined by double electron-electron resonance. Biochemistry (2006) 1.20
Regulation of chromatin structure and function by HMGN proteins. Biochim Biophys Acta (2009) 1.18
Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils. Mol Biochem Parasitol (2009) 1.14
Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis. BMC Evol Biol (2006) 1.12
Amyloidogenesis of natively unfolded proteins. Curr Alzheimer Res (2008) 1.08
Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1. Biochem Biophys Res Commun (2011) 1.08
Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis. J Virol (2007) 1.06
Effects of HMGN variants on the cellular transcription profile. Nucleic Acids Res (2011) 1.05
Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products. Proc Natl Acad Sci U S A (2008) 1.03
The 24-angstrom structure of respiratory syncytial virus nucleocapsid protein-RNA decameric rings. J Virol (2007) 0.98
Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be. Bioinformatics (2010) 0.98
Emerging models for the molecular basis of mammalian circadian timing. Biochemistry (2014) 0.98
Genome pool strategy for structural coverage of protein families. Structure (2008) 0.97
Osmolytes modulate conformational exchange in solvent-exposed regions of membrane proteins. Protein Sci (2010) 0.97
Vaccinia H5 is a multifunctional protein involved in viral DNA replication, postreplicative gene transcription, and virion morphogenesis. Virology (2010) 0.91
Single-stranded DNA binding by F TraI relaxase and helicase domains is coordinately regulated. J Bacteriol (2010) 0.89
Epigenetic regulation of the mammalian cell. PLoS One (2008) 0.89
Differential regulation of the transcriptional activity of the glucocorticoid receptor through site-specific phosphorylation. Biologics (2008) 0.87
Properties of protein drug target classes. PLoS One (2015) 0.84
TBP binding-induced folding of the glucocorticoid receptor AF1 domain facilitates its interaction with steroid receptor coactivator-1. PLoS One (2011) 0.84
Effects of different osmolytes on the induced folding of the N-terminal activation domain (AF1) of the glucocorticoid receptor. Arch Biochem Biophys (2007) 0.83
The twilight zone between protein order and disorder. Biophys J (2008) 0.82
Polyglutamine expansion alters the dynamics and molecular architecture of aggregates in dentatorubropallidoluysian atrophy. J Biol Chem (2011) 0.81
The cPLA2 C2alpha domain in solution: structure and dynamics of its Ca2+-activated and cation-free states. Biophys J (2006) 0.81
FlgM proteins from different bacteria exhibit different structural characteristics. Biochim Biophys Acta (2013) 0.80
Simple sequence proteins in prokaryotic proteomes. BMC Genomics (2006) 0.80
Small acid-soluble proteins with intrinsic disorder are required for UV resistance in Myxococcus xanthus spores. J Bacteriol (2011) 0.79
Exploring the link between MORF4L1 and risk of breast cancer. Breast Cancer Res (2011) 0.79
Biochemistry that times the day. Biochemistry (2014) 0.77
Optimal design of thermally stable proteins. Bioinformatics (2008) 0.76
An overview of the importance of conformational flexibility in gene regulation by the transcription factors. J Biophys (2010) 0.76
Alternative splicing and the evolution of phenotypic novelty. Philos Trans R Soc Lond B Biol Sci (2017) 0.76
Cysteine-free proteins in the immunobiology of arthropod-borne diseases. J Biomed Biotechnol (2010) 0.75
The importance of intrinsic disorder for protein phosphorylation. Nucleic Acids Res (2004) 8.23
Intrinsic disorder in cell-signaling and cancer-associated proteins. J Mol Biol (2002) 5.64
DisProt: the Database of Disordered Proteins. Nucleic Acids Res (2006) 4.46
Understanding protein non-folding. Biochim Biophys Acta (2010) 4.33
Intrinsically disordered proteins in human diseases: introducing the D2 concept. Annu Rev Biophys (2008) 3.98
Intrinsic disorder and functional proteomics. Biophys J (2006) 3.84
Length-dependent prediction of protein intrinsic disorder. BMC Bioinformatics (2006) 3.70
PONDR-FIT: a meta-predictor of intrinsically disordered amino acids. Biochim Biophys Acta (2010) 3.62
Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling. J Mol Recognit (2005) 3.57
Analysis of molecular recognition features (MoRFs). J Mol Biol (2006) 3.40
Exploiting heterogeneous sequence properties improves prediction of protein disorder. Proteins (2005) 3.14
Intrinsic disorder in transcription factors. Biochemistry (2006) 3.06
Coupled folding and binding with alpha-helix-forming molecular recognition elements. Biochemistry (2005) 2.94
Predicting intrinsic disorder from amino acid sequence. Proteins (2003) 2.74
Flavors of protein disorder. Proteins (2003) 2.72
The unfoldomics decade: an update on intrinsically disordered proteins. BMC Genomics (2008) 2.72
Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions. J Proteome Res (2007) 2.61
Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms. Proc Natl Acad Sci U S A (2006) 2.57
Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners. BMC Genomics (2008) 2.50
Classification of intrinsically disordered regions and proteins. Chem Rev (2014) 2.48
Evolutionary rate heterogeneity in proteins with long disordered regions. J Mol Evol (2002) 2.46
Comparing and combining predictors of mostly disordered proteins. Biochemistry (2005) 2.45
Protein flexibility and intrinsic disorder. Protein Sci (2004) 2.33
Predicting intrinsic disorder in proteins: an overview. Cell Res (2009) 2.24
A protein domain-based interactome network for C. elegans early embryogenesis. Cell (2008) 2.23
Characterization of molecular recognition features, MoRFs, and their binding partners. J Proteome Res (2007) 2.23
Identification and functions of usefully disordered proteins. Adv Protein Chem (2002) 2.23
Optimizing long intrinsic disorder predictors with protein evolutionary information. J Bioinform Comput Biol (2005) 2.20
DisProt: a database of protein disorder. Bioinformatics (2004) 1.99
Mining alpha-helix-forming molecular recognition features with cross species sequence alignments. Biochemistry (2007) 1.93
Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins. J Proteome Res (2007) 1.92
Disorder and sequence repeats in hub proteins and their implications for network evolution. J Proteome Res (2006) 1.87
Intrinsically disordered proteins and intrinsically disordered protein regions. Annu Rev Biochem (2014) 1.79
D²P²: database of disordered protein predictions. Nucleic Acids Res (2012) 1.75
Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J Biol Chem (2007) 1.74
TOP-IDP-scale: a new amino acid scale measuring propensity for intrinsic disorder. Protein Pept Lett (2008) 1.70
Composition Profiler: a tool for discovery and visualization of amino acid composition differences. BMC Bioinformatics (2007) 1.64
Alternative splicing of intrinsically disordered regions and rewiring of protein interactions. Curr Opin Struct Biol (2013) 1.61
Rational drug design via intrinsically disordered protein. Trends Biotechnol (2006) 1.57
Close encounters of the third kind: disordered domains and the interactions of proteins. Bioessays (2009) 1.56
Musite, a tool for global prediction of general and kinase-specific phosphorylation sites. Mol Cell Proteomics (2010) 1.55
Statistical analysis of interface similarity in crystals of homologous proteins. J Mol Biol (2008) 1.55
Calmodulin signaling: analysis and prediction of a disorder-dependent molecular recognition. Proteins (2006) 1.51
Combining prediction, computation and experiment for the characterization of protein disorder. Curr Opin Struct Biol (2004) 1.51
Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life. J Biomol Struct Dyn (2012) 1.51
Evolution and disorder. Curr Opin Struct Biol (2011) 1.50
MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins. Bioinformatics (2012) 1.49
Comparing skeletal and cardiac calsequestrin structures and their calcium binding: a proposed mechanism for coupled calcium binding and protein polymerization. J Biol Chem (2004) 1.49
Intrinsic disorder in scaffold proteins: getting more from less. Prog Biophys Mol Biol (2008) 1.49
Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions. J Proteome Res (2007) 1.48
Unfoldomics of human genetic diseases: illustrative examples of ordered and intrinsically disordered members of the human diseasome. Protein Pept Lett (2009) 1.45
Addressing the intrinsic disorder bottleneck in structural proteomics. Proteins (2005) 1.44
Overlapping genes produce proteins with unusual sequence properties and offer insight into de novo protein creation. J Virol (2009) 1.42
Conservation of intrinsic disorder in protein domains and families: I. A database of conserved predicted disordered regions. J Proteome Res (2006) 1.42
Unfoldomics of human diseases: linking protein intrinsic disorder with diseases. BMC Genomics (2009) 1.41
Polymerization of calsequestrin. Implications for Ca2+ regulation. J Biol Chem (2003) 1.39
Intrinsic disorder in the Protein Data Bank. J Biomol Struct Dyn (2007) 1.37
Signal transduction via unstructured protein conduits. Nat Chem Biol (2008) 1.36
Malleable machines in transcription regulation: the mediator complex. PLoS Comput Biol (2008) 1.35
Improved amino acid flexibility parameters. Protein Sci (2003) 1.34
SPINE-D: accurate prediction of short and long disordered regions by a single neural-network based method. J Biomol Struct Dyn (2012) 1.32
Conservation of intrinsic disorder in protein domains and families: II. functions of conserved disorder. J Proteome Res (2006) 1.27
Exploring the binding diversity of intrinsically disordered proteins involved in one-to-many binding. Protein Sci (2013) 1.23
Abundance of intrinsic disorder in protein associated with cardiovascular disease. Biochemistry (2006) 1.19
Classification and knowledge discovery in protein databases. J Biomed Inform (2004) 1.18
Protein intrinsic disorder and human papillomaviruses: increased amount of disorder in E6 and E7 oncoproteins from high risk HPVs. J Proteome Res (2006) 1.17
A computational investigation of allostery in the catabolite activator protein. J Am Chem Soc (2007) 1.17
Prediction of boundaries between intrinsically ordered and disordered protein regions. Pac Symp Biocomput (2003) 1.16
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Res (2013) 1.13
Substring selection for biomedical document classification. Bioinformatics (2006) 1.13
Protein disorder in the human diseasome: unfoldomics of human genetic diseases. BMC Genomics (2009) 1.11
DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease? BMC Med Genomics (2012) 1.11
ProtBuD: a database of biological unit structures of protein families and superfamilies. Bioinformatics (2006) 1.09
Selective control of gene expression by CDK9 in human cells. J Cell Physiol (2010) 1.06
Archaic chaos: intrinsically disordered proteins in Archaea. BMC Syst Biol (2010) 1.05
Analysis of structured and intrinsically disordered regions of transmembrane proteins. Mol Biosyst (2009) 1.05
The structural and functional signatures of proteins that undergo multiple events of post-translational modification. Protein Sci (2014) 1.05
Intrinsic disorder in pathogenic and non-pathogenic microbes: discovering and analyzing the unfoldomes of early-branching eukaryotes. Mol Biosyst (2008) 1.03
CDF it all: consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions. FEBS Lett (2009) 1.03
Short Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regions. BMC Genomics (2008) 1.01