PubRank

Rainer Rudolph

Author PubWeight™ 49.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain. J Biol Chem 2008 2.51
2 Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor. Proc Natl Acad Sci U S A 2007 2.13
3 Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor. J Biol Chem 2009 1.94
4 Passing the baton in class B GPCRs: peptide hormone activation via helix induction? Trends Biochem Sci 2009 1.89
5 Primary structure elements of spider dragline silks and their contribution to protein solubility. Biochemistry 2004 1.48
6 Artificial, non-antibody binding proteins for pharmaceutical and industrial applications. Trends Biotechnol 2005 1.24
7 The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1. J Biol Chem 2003 1.19
8 Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain. Biochemistry 2007 1.14
9 Catalytic activity and chaperone function of human protein-disulfide isomerase are required for the efficient refolding of proinsulin. J Biol Chem 2001 1.08
10 In vitro folding, functional characterization, and disulfide pattern of the extracellular domain of human GLP-1 receptor. Biophys Chem 2002 1.03
11 Killing of target cells by redirected granzyme B in the absence of perforin. FEBS Lett 2004 0.99
12 L-Arginine increases the solubility of unfolded species of hen egg white lysozyme. Protein Sci 2005 0.97
13 Trinucleotide expansions leading to an extended poly-L-alanine segment in the poly (A) binding protein PABPN1 cause fibril formation. Protein Sci 2003 0.95
14 Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody. J Mol Biol 2008 0.94
15 Renaturation of human proinsulin--a study on refolding and conversion to insulin. Anal Biochem 2002 0.93
16 Identification of a disulfide bridge essential for transport function of the human proton-coupled amino acid transporter hPAT1. J Biol Chem 2009 0.92
17 Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain. J Mol Biol 2005 0.90
18 High yield production of recombinant native and modified peptides exemplified by ligands for G-protein coupled receptors. Protein Expr Purif 2008 0.90
19 Biophysical comparison of BMP-2, ProBMP-2, and the free pro-peptide reveals stabilization of the pro-peptide by the mature growth factor. J Biol Chem 2005 0.88
20 Suppression of protein aggregation by L-arginine. Curr Pharm Biotechnol 2009 0.87
21 Recombinant expression, in vitro refolding, and biophysical characterization of the human glucagon-like peptide-1 receptor. Biochemistry 2010 0.87
22 Affilin-novel binding molecules based on human gamma-B-crystallin, an all beta-sheet protein. J Mol Biol 2007 0.86
23 The mature part of proNGF induces the structure of its pro-peptide. FEBS Lett 2004 0.85
24 Mammalian G-protein-coupled receptor expression in Escherichia coli: I. High-throughput large-scale production as inclusion bodies. Anal Biochem 2008 0.85
25 Mammalian G protein-coupled receptor expression in Escherichia coli: II. Refolding and biophysical characterization of mouse cannabinoid receptor 1 and human parathyroid hormone receptor 1. Anal Biochem 2010 0.85
26 Impact of N-terminal domains for corticotropin-releasing factor (CRF) receptor-ligand interactions. Biochemistry 2005 0.85
27 Ionic liquids as refolding additives: N'-alkyl and N'-(omega-hydroxyalkyl) N-methylimidazolium chlorides. Protein Sci 2005 0.85
28 Hexa-histidin tag position influences disulfide structure but not binding behavior of in vitro folded N-terminal domain of rat corticotropin-releasing factor receptor type 2a. Protein Sci 2004 0.85
29 Intradomain disulfide bonds impede formation of the alternatively folded state of antibody chains. J Mol Biol 2002 0.85
30 The pro-peptide of proNGF: structure formation and intramolecular association with NGF. Protein Sci 2007 0.84
31 L-arginine hydrochloride increases the solubility of folded and unfolded recombinant plasminogen activator rPA. Protein Sci 2010 0.84
32 A novel fusion protein system for the production of native human pepsinogen in the bacterial periplasm. Protein Expr Purif 2006 0.82
33 Recombinant human hyaluronidase Hyal-1: insect cells versus Escherichia coli as expression system and identification of low molecular weight inhibitors. Glycobiology 2007 0.82
34 Periplasmic production of native human proinsulin as a fusion to E. coli ecotin. Protein Expr Purif 2007 0.82
35 The role of N-glycosylation in transport function and surface targeting of the human solute carrier PAT1. FEBS Lett 2009 0.81
36 A tetrapeptide fragment-based design method results in highly stable artificial proteins. Proteins 2007 0.81
37 Oxidative folding of nerve growth factor can be mediated by the pro-peptide of neurotrophin-3. FEBS Lett 2007 0.81
38 Binding specificity of the ectodomain of the parathyroid hormone receptor. Biophys Chem 2011 0.80
39 Expression and purification of His-tagged HPV16 E7 protein active in pRb binding. Protein Expr Purif 2006 0.80
40 New binding mode to TNF-alpha revealed by ubiquitin-based artificial binding protein. PLoS One 2012 0.80
41 Ionic liquids as refolding additives: variation of the anion. J Biotechnol 2010 0.80
42 The non-ionic detergent Brij 58P mimics chaperone effects. FEBS Lett 2002 0.80
43 Recombinant expression and in vitro folding of proinsulin are stimulated by the synthetic dithiol Vectrase-P. FEMS Microbiol Lett 2002 0.79
44 Ionic liquids and proteases: a clean alliance for semisynthesis. Chembiochem 2008 0.79
45 Design of a modular immunotoxin connected by polyionic adapter peptides. J Mol Biol 2003 0.79
46 Recombinant production of bioactive human TNF-alpha by SUMO-fusion system--high yields from shake-flask culture. Protein Expr Purif 2010 0.78
47 The NMR solution structure of the artificial protein M7 matches the computationally designed model. Proteins 2008 0.77
48 Affilin molecules selected against the human papillomavirus E7 protein inhibit the proliferation of target cells. J Mol Biol 2009 0.77
49 Examination of the slow unfolding of pro-nerve growth factor argues against a loop threading mechanism for nerve growth factor. Biochemistry 2006 0.77
50 Prokaryotic expression, in vitro folding, and molecular pharmacological characterization of the neuropeptide Y receptor type 2. Biotechnol Prog 2009 0.76
51 In vitro-refolding of a single-chain Fv fragment in the presence of heteroaromatic thiols. J Biotechnol 2008 0.75
52 Use of enhanced green fluorescent protein to determine pepsin at high sensitivity. Anal Biochem 2005 0.75
53 Enhancing the fluorescence of tyr-59 in ubiquitin by blocking proton transfer. Phys Chem Chem Phys 2009 0.75