Published in FEBS Lett on August 06, 2007
Proneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation. J Biol Chem (2008) 1.05
Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosis. J Biol Chem (2012) 0.88
HBpF-proBDNF: A New Tool for the Analysis of Pro-Brain Derived Neurotrophic Factor Receptor Signaling and Cell Biology. PLoS One (2016) 0.75
Sortilin is essential for proNGF-induced neuronal cell death. Nature (2004) 5.62
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain. J Biol Chem (2008) 2.51
Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor. Proc Natl Acad Sci U S A (2007) 2.13
Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control. Oncogene (2002) 2.09
Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. Cell Metab (2010) 1.94
Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor. J Biol Chem (2009) 1.94
Passing the baton in class B GPCRs: peptide hormone activation via helix induction? Trends Biochem Sci (2009) 1.89
Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA. Mol Cell Biol (2007) 1.70
Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA. EMBO J (2003) 1.55
Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing. J Neurosci (2012) 1.52
Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain. Nat Struct Mol Biol (2009) 1.50
The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding. FEBS Lett (2002) 1.48
Primary structure elements of spider dragline silks and their contribution to protein solubility. Biochemistry (2004) 1.48
p16(INK4a) overexpression predicts translational active human papillomavirus infection in tonsillar cancer. Int J Cancer (2010) 1.34
Artificial, non-antibody binding proteins for pharmaceutical and industrial applications. Trends Biotechnol (2005) 1.24
Human papillomaviruses in head and neck cancer: 8 year-survival-analysis of 73 patients. Cancer Lett (2005) 1.22
Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas. PLoS One (2013) 1.19
The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1. J Biol Chem (2003) 1.19
Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain. Biochemistry (2007) 1.14
Analysis of human papillomavirus type 16 (HPV16) DNA load and physical state for identification of HPV16-infected women with high-grade lesions or cervical carcinoma. J Clin Microbiol (2008) 1.09
Catalytic activity and chaperone function of human protein-disulfide isomerase are required for the efficient refolding of proinsulin. J Biol Chem (2001) 1.08
Functional organization of the sortilin Vps10p domain. J Biol Chem (2004) 1.05
In vitro folding, functional characterization, and disulfide pattern of the extracellular domain of human GLP-1 receptor. Biophys Chem (2002) 1.03
p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies. J Biol Chem (2004) 1.02
The yeast Vps10p cytoplasmic tail mediates lysosomal sorting in mammalian cells and interacts with human GGAs. J Biol Chem (2002) 1.01
Killing of target cells by redirected granzyme B in the absence of perforin. FEBS Lett (2004) 0.99
Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina. BMC Urol (2005) 0.99
Different motifs regulate trafficking of SorCS1 isoforms. Traffic (2008) 0.98
Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons. Eur J Neurosci (2011) 0.97
L-Arginine increases the solubility of unfolded species of hen egg white lysozyme. Protein Sci (2005) 0.97
Intrinsic structural disorder of mouse proNGF. Proteins (2009) 0.96
Trinucleotide expansions leading to an extended poly-L-alanine segment in the poly (A) binding protein PABPN1 cause fibril formation. Protein Sci (2003) 0.95
Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody. J Mol Biol (2008) 0.94
Renaturation of human proinsulin--a study on refolding and conversion to insulin. Anal Biochem (2002) 0.93
Identification of a disulfide bridge essential for transport function of the human proton-coupled amino acid transporter hPAT1. J Biol Chem (2009) 0.92
Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting. BMC Cancer (2009) 0.92
Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein. J Neurosci (2013) 0.92
Smad4 deficiency in cervical carcinoma cells. Oncogene (2005) 0.91
Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy. EMBO Mol Med (2011) 0.91
Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells. J Biol Chem (2002) 0.91
Structural and dynamical characterization of fibrils from a disease-associated alanine expansion domain using proteolysis and solid-state NMR spectroscopy. J Am Chem Soc (2008) 0.91
High yield production of recombinant native and modified peptides exemplified by ligands for G-protein coupled receptors. Protein Expr Purif (2008) 0.90
Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain. J Mol Biol (2005) 0.90
GGA autoinhibition revisited. Traffic (2009) 0.89
Human papillomaviruses in lymph node neck metastases of head and neck cancers. Acta Otolaryngol (2005) 0.89
Sortilin is a putative postendocytic receptor of thyroglobulin. Endocrinology (2008) 0.88
Biophysical comparison of BMP-2, ProBMP-2, and the free pro-peptide reveals stabilization of the pro-peptide by the mature growth factor. J Biol Chem (2005) 0.88
Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosis. J Biol Chem (2012) 0.88
Suppression of protein aggregation by L-arginine. Curr Pharm Biotechnol (2009) 0.87
Hofmeister salts and potential therapeutic compounds accelerate in vitro fibril formation of the N-terminal domain of PABPN1 containing a disease-causing alanine extension. Biochemistry (2008) 0.87
Recombinant expression, in vitro refolding, and biophysical characterization of the human glucagon-like peptide-1 receptor. Biochemistry (2010) 0.87
Detection of human papillomavirus DNA in benign and malignant sinonasal neoplasms. Cancer Lett (2005) 0.86
Affilin-novel binding molecules based on human gamma-B-crystallin, an all beta-sheet protein. J Mol Biol (2007) 0.86
The mature part of proNGF induces the structure of its pro-peptide. FEBS Lett (2004) 0.85
Expression of single-chain variable fragments fused with the Fc-region of rabbit IgG in Leishmania tarentolae. Microb Cell Fact (2014) 0.85
Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin. Protein Sci (2014) 0.85
Impact of N-terminal domains for corticotropin-releasing factor (CRF) receptor-ligand interactions. Biochemistry (2005) 0.85
Mammalian G protein-coupled receptor expression in Escherichia coli: II. Refolding and biophysical characterization of mouse cannabinoid receptor 1 and human parathyroid hormone receptor 1. Anal Biochem (2010) 0.85
Hexa-histidin tag position influences disulfide structure but not binding behavior of in vitro folded N-terminal domain of rat corticotropin-releasing factor receptor type 2a. Protein Sci (2004) 0.85
The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding. FEBS J (2009) 0.85
Mammalian G-protein-coupled receptor expression in Escherichia coli: I. High-throughput large-scale production as inclusion bodies. Anal Biochem (2008) 0.85
Ionic liquids as refolding additives: N'-alkyl and N'-(omega-hydroxyalkyl) N-methylimidazolium chlorides. Protein Sci (2005) 0.85
Intradomain disulfide bonds impede formation of the alternatively folded state of antibody chains. J Mol Biol (2002) 0.85
SMAD4: a predictive marker of PDAC cell permissiveness for oncolytic infection with parvovirus H-1PV. Int J Cancer (2010) 0.84
Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer. Mol Cell Biol (2010) 0.84
The pro-peptide of proNGF: structure formation and intramolecular association with NGF. Protein Sci (2007) 0.84
L-arginine hydrochloride increases the solubility of folded and unfolded recombinant plasminogen activator rPA. Protein Sci (2010) 0.84
The influence of covalently linked and free polyethylene glycol on the structural and release properties of rhBMP-2 loaded microspheres. J Control Release (2010) 0.83
Human papillomavirus type 16 E6 and E7 genotypes in head-and-neck carcinomas. Oral Oncol (2004) 0.83
Periplasmic production of native human proinsulin as a fusion to E. coli ecotin. Protein Expr Purif (2007) 0.82
Effect of oculopharyngeal muscular dystrophy-associated extension of seven alanines on the fibrillation properties of the N-terminal domain of PABPN1. FEBS J (2007) 0.82
A folded and functional protein domain in an amyloid-like fibril. Protein Sci (2008) 0.82
A novel fusion protein system for the production of native human pepsinogen in the bacterial periplasm. Protein Expr Purif (2006) 0.82
Recombinant human hyaluronidase Hyal-1: insect cells versus Escherichia coli as expression system and identification of low molecular weight inhibitors. Glycobiology (2007) 0.82
Polyalanine-independent conformational conversion of nuclear poly(A)-binding protein 1 (PABPN1). J Biol Chem (2012) 0.82
HPV16 DNA in histologically confirmed tumour-free neck lymph nodes of head and neck cancers. Anticancer Res (2006) 0.82
A tetrapeptide fragment-based design method results in highly stable artificial proteins. Proteins (2007) 0.81
The role of N-glycosylation in transport function and surface targeting of the human solute carrier PAT1. FEBS Lett (2009) 0.81
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET. Cell Rep (2013) 0.81
Expression and purification of His-tagged HPV16 E7 protein active in pRb binding. Protein Expr Purif (2006) 0.80
Identification of a core domain within the proregion of bone morphogenetic proteins that interacts with the dimeric, mature domain. Biochem Biophys Res Commun (2011) 0.80
Binding specificity of the ectodomain of the parathyroid hormone receptor. Biophys Chem (2011) 0.80
New binding mode to TNF-alpha revealed by ubiquitin-based artificial binding protein. PLoS One (2012) 0.80
The non-ionic detergent Brij 58P mimics chaperone effects. FEBS Lett (2002) 0.80
Ionic liquids as refolding additives: variation of the anion. J Biotechnol (2010) 0.80
Treatment with bone morphogenetic protein 2 limits infarct size after myocardial infarction in mice. Shock (2013) 0.80
ABSENCE OF A THYROID PHENOTYPE IN SORTILIN-DEFICIENT MICE. Endocr Pract (2015) 0.79
Monitoring fibril formation of the N-terminal domain of PABPN1 carrying an alanine repeat by tryptophan fluorescence and real-time NMR. FEBS Lett (2008) 0.79
Ionic liquids and proteases: a clean alliance for semisynthesis. Chembiochem (2008) 0.79
High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition. BMC Cancer (2007) 0.79
The unresolved puzzle why alanine extensions cause disease. Biol Chem (2013) 0.79
Design of a modular immunotoxin connected by polyionic adapter peptides. J Mol Biol (2003) 0.79