Published in J Biol Chem on February 04, 2005
Studies of bone morphogenetic protein-based surgical repair. Adv Drug Deliv Rev (2012) 1.13
Bidirectional, optical sign-dependent regulation of BMP2 gene expression in chick retinal pigment epithelium. Invest Ophthalmol Vis Sci (2012) 1.00
The pro-peptide of proNGF: structure formation and intramolecular association with NGF. Protein Sci (2007) 0.84
Release characteristics and osteogenic activity of recombinant human bone morphogenetic protein-2 grafted to novel self-assembled poly(lactide-co-glycolide fumarate) nanoparticles. J Control Release (2009) 0.83
Secondary structure of rhBMP-2 in a protective biopolymeric carrier material. Biomacromolecules (2012) 0.80
Effect of grafting BMP2-derived peptide to nanoparticles on osteogenic and vasculogenic expression of stromal cells. J Tissue Eng Regen Med (2012) 0.78
A novel bone morphogenetic protein 2 mutant mouse, nBmp2NLS(tm), displays impaired intracellular Ca2+ handling in skeletal muscle. Biomed Res Int (2013) 0.78
The C313Y Piedmontese mutation decreases myostatin covalent dimerisation and stability. BMC Res Notes (2011) 0.75
The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory. Sci Rep (2017) 0.75
The factor VII-activating protease (FSAP) enhances the activity of bone morphogenetic protein-2 (BMP-2). J Biol Chem (2013) 0.75
BMP2-modified injectable hydrogel for osteogenic differentiation of human periodontal ligament stem cells. Sci Rep (2017) 0.75
Sortilin is essential for proNGF-induced neuronal cell death. Nature (2004) 5.62
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain. J Biol Chem (2008) 2.51
Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor. Proc Natl Acad Sci U S A (2007) 2.13
Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control. Oncogene (2002) 2.09
Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor. J Biol Chem (2009) 1.94
Passing the baton in class B GPCRs: peptide hormone activation via helix induction? Trends Biochem Sci (2009) 1.89
Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA. EMBO J (2003) 1.55
Primary structure elements of spider dragline silks and their contribution to protein solubility. Biochemistry (2004) 1.48
p16(INK4a) overexpression predicts translational active human papillomavirus infection in tonsillar cancer. Int J Cancer (2010) 1.34
Artificial, non-antibody binding proteins for pharmaceutical and industrial applications. Trends Biotechnol (2005) 1.24
Human papillomaviruses in head and neck cancer: 8 year-survival-analysis of 73 patients. Cancer Lett (2005) 1.22
Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas. PLoS One (2013) 1.19
The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1. J Biol Chem (2003) 1.19
Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain. Biochemistry (2007) 1.14
Analysis of human papillomavirus type 16 (HPV16) DNA load and physical state for identification of HPV16-infected women with high-grade lesions or cervical carcinoma. J Clin Microbiol (2008) 1.09
Catalytic activity and chaperone function of human protein-disulfide isomerase are required for the efficient refolding of proinsulin. J Biol Chem (2001) 1.08
In vitro folding, functional characterization, and disulfide pattern of the extracellular domain of human GLP-1 receptor. Biophys Chem (2002) 1.03
Killing of target cells by redirected granzyme B in the absence of perforin. FEBS Lett (2004) 0.99
Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina. BMC Urol (2005) 0.99
Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons. Eur J Neurosci (2011) 0.97
L-Arginine increases the solubility of unfolded species of hen egg white lysozyme. Protein Sci (2005) 0.97
Intrinsic structural disorder of mouse proNGF. Proteins (2009) 0.96
Trinucleotide expansions leading to an extended poly-L-alanine segment in the poly (A) binding protein PABPN1 cause fibril formation. Protein Sci (2003) 0.95
Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody. J Mol Biol (2008) 0.94
Renaturation of human proinsulin--a study on refolding and conversion to insulin. Anal Biochem (2002) 0.93
Identification of a disulfide bridge essential for transport function of the human proton-coupled amino acid transporter hPAT1. J Biol Chem (2009) 0.92
Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting. BMC Cancer (2009) 0.92
Smad4 deficiency in cervical carcinoma cells. Oncogene (2005) 0.91
Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy. EMBO Mol Med (2011) 0.91
Structural and dynamical characterization of fibrils from a disease-associated alanine expansion domain using proteolysis and solid-state NMR spectroscopy. J Am Chem Soc (2008) 0.91
Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain. J Mol Biol (2005) 0.90
High yield production of recombinant native and modified peptides exemplified by ligands for G-protein coupled receptors. Protein Expr Purif (2008) 0.90
Human papillomaviruses in lymph node neck metastases of head and neck cancers. Acta Otolaryngol (2005) 0.89
Suppression of protein aggregation by L-arginine. Curr Pharm Biotechnol (2009) 0.87
Recombinant expression, in vitro refolding, and biophysical characterization of the human glucagon-like peptide-1 receptor. Biochemistry (2010) 0.87
Hofmeister salts and potential therapeutic compounds accelerate in vitro fibril formation of the N-terminal domain of PABPN1 containing a disease-causing alanine extension. Biochemistry (2008) 0.87
Detection of human papillomavirus DNA in benign and malignant sinonasal neoplasms. Cancer Lett (2005) 0.86
Affilin-novel binding molecules based on human gamma-B-crystallin, an all beta-sheet protein. J Mol Biol (2007) 0.86
The mature part of proNGF induces the structure of its pro-peptide. FEBS Lett (2004) 0.85
Mammalian G-protein-coupled receptor expression in Escherichia coli: I. High-throughput large-scale production as inclusion bodies. Anal Biochem (2008) 0.85
Intradomain disulfide bonds impede formation of the alternatively folded state of antibody chains. J Mol Biol (2002) 0.85
Hexa-histidin tag position influences disulfide structure but not binding behavior of in vitro folded N-terminal domain of rat corticotropin-releasing factor receptor type 2a. Protein Sci (2004) 0.85
Mammalian G protein-coupled receptor expression in Escherichia coli: II. Refolding and biophysical characterization of mouse cannabinoid receptor 1 and human parathyroid hormone receptor 1. Anal Biochem (2010) 0.85
Ionic liquids as refolding additives: N'-alkyl and N'-(omega-hydroxyalkyl) N-methylimidazolium chlorides. Protein Sci (2005) 0.85
Impact of N-terminal domains for corticotropin-releasing factor (CRF) receptor-ligand interactions. Biochemistry (2005) 0.85
The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding. FEBS J (2009) 0.85
SMAD4: a predictive marker of PDAC cell permissiveness for oncolytic infection with parvovirus H-1PV. Int J Cancer (2010) 0.84
The pro-peptide of proNGF: structure formation and intramolecular association with NGF. Protein Sci (2007) 0.84
L-arginine hydrochloride increases the solubility of folded and unfolded recombinant plasminogen activator rPA. Protein Sci (2010) 0.84
The influence of covalently linked and free polyethylene glycol on the structural and release properties of rhBMP-2 loaded microspheres. J Control Release (2010) 0.83
Human papillomavirus type 16 E6 and E7 genotypes in head-and-neck carcinomas. Oral Oncol (2004) 0.83
Periplasmic production of native human proinsulin as a fusion to E. coli ecotin. Protein Expr Purif (2007) 0.82
A folded and functional protein domain in an amyloid-like fibril. Protein Sci (2008) 0.82
Effect of oculopharyngeal muscular dystrophy-associated extension of seven alanines on the fibrillation properties of the N-terminal domain of PABPN1. FEBS J (2007) 0.82
A novel fusion protein system for the production of native human pepsinogen in the bacterial periplasm. Protein Expr Purif (2006) 0.82
Recombinant human hyaluronidase Hyal-1: insect cells versus Escherichia coli as expression system and identification of low molecular weight inhibitors. Glycobiology (2007) 0.82
Polyalanine-independent conformational conversion of nuclear poly(A)-binding protein 1 (PABPN1). J Biol Chem (2012) 0.82
HPV16 DNA in histologically confirmed tumour-free neck lymph nodes of head and neck cancers. Anticancer Res (2006) 0.82
A tetrapeptide fragment-based design method results in highly stable artificial proteins. Proteins (2007) 0.81
The role of N-glycosylation in transport function and surface targeting of the human solute carrier PAT1. FEBS Lett (2009) 0.81
Oxidative folding of nerve growth factor can be mediated by the pro-peptide of neurotrophin-3. FEBS Lett (2007) 0.81
Expression and purification of His-tagged HPV16 E7 protein active in pRb binding. Protein Expr Purif (2006) 0.80
Identification of a core domain within the proregion of bone morphogenetic proteins that interacts with the dimeric, mature domain. Biochem Biophys Res Commun (2011) 0.80
Treatment with bone morphogenetic protein 2 limits infarct size after myocardial infarction in mice. Shock (2013) 0.80
Binding specificity of the ectodomain of the parathyroid hormone receptor. Biophys Chem (2011) 0.80
The non-ionic detergent Brij 58P mimics chaperone effects. FEBS Lett (2002) 0.80
New binding mode to TNF-alpha revealed by ubiquitin-based artificial binding protein. PLoS One (2012) 0.80
Ionic liquids as refolding additives: variation of the anion. J Biotechnol (2010) 0.80
Design of a modular immunotoxin connected by polyionic adapter peptides. J Mol Biol (2003) 0.79
Ionic liquids and proteases: a clean alliance for semisynthesis. Chembiochem (2008) 0.79
The unresolved puzzle why alanine extensions cause disease. Biol Chem (2013) 0.79
Recombinant expression and in vitro folding of proinsulin are stimulated by the synthetic dithiol Vectrase-P. FEMS Microbiol Lett (2002) 0.79
High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition. BMC Cancer (2007) 0.79
Monitoring fibril formation of the N-terminal domain of PABPN1 carrying an alanine repeat by tryptophan fluorescence and real-time NMR. FEBS Lett (2008) 0.79
Biophysical and structural characterization of a folded core domain within the proregion of growth and differentiation factor-5. FEBS J (2014) 0.78
The pro-form of BMP-2 exhibits a delayed and reduced activity when compared to mature BMP-2. Growth Factors (2011) 0.78
Ectopic expression of nonliganded retinoic acid receptor beta abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells. J Biol Chem (2004) 0.78
Recombinant production of bioactive human TNF-alpha by SUMO-fusion system--high yields from shake-flask culture. Protein Expr Purif (2010) 0.78
Influence of the stability of a fused protein and its distance to the amyloidogenic segment on fibril formation. PLoS One (2010) 0.78
The NMR solution structure of the artificial protein M7 matches the computationally designed model. Proteins (2008) 0.77
Different morphology of amyloid fibrils originating from agitated and non-agitated conditions. Amyloid (2013) 0.77
Examination of the slow unfolding of pro-nerve growth factor argues against a loop threading mechanism for nerve growth factor. Biochemistry (2006) 0.77
Affilin molecules selected against the human papillomavirus E7 protein inhibit the proliferation of target cells. J Mol Biol (2009) 0.77
A core domain of the BMP2 proregion is sufficient for the biogenesis of mature homodimeric growth factor. Biol Chem (2015) 0.76
Prokaryotic expression, in vitro folding, and molecular pharmacological characterization of the neuropeptide Y receptor type 2. Biotechnol Prog (2009) 0.76
Feasibility of newborn screening for guanidinoacetate methyltransferase (GAMT) deficiency. J Inherit Metab Dis (2013) 0.76
The factor VII-activating protease (FSAP) enhances the activity of bone morphogenetic protein-2 (BMP-2). J Biol Chem (2013) 0.75
In vitro-refolding of a single-chain Fv fragment in the presence of heteroaromatic thiols. J Biotechnol (2008) 0.75
Influence of the polypeptide environment next to amyloidogenic peptides on fibril formation. Biol Chem (2014) 0.75
Enhancing the fluorescence of tyr-59 in ubiquitin by blocking proton transfer. Phys Chem Chem Phys (2009) 0.75
Real-time duplex PCR for simultaneous HPV 16 and HPV 18 DNA quantitation. J Virol Methods (2013) 0.75
Use of enhanced green fluorescent protein to determine pepsin at high sensitivity. Anal Biochem (2005) 0.75