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1
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ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading.
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Cancer Cell
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2010
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3.25
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2
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Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition.
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J Cell Biol
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2005
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2.88
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3
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VEGF targets the tumour cell.
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Nat Rev Cancer
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2013
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2.71
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4
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Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma.
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J Clin Invest
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2005
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2.61
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5
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IAP regulation of metastasis.
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Cancer Cell
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2010
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2.47
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6
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Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.
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Cancer Res
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2002
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2.20
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7
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Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids.
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Mol Biol Cell
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2003
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2.11
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8
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The epithelial-mesenchymal transition (EMT) and colorectal cancer progression.
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Cancer Biol Ther
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2005
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2.10
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9
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Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells.
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Cancer Res
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2003
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1.95
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10
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Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma.
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Cancer Res
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2004
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1.83
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11
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Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells.
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J Cell Biol
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2002
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1.66
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12
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Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the alpha6beta4 integrin.
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Cancer Res
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2005
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1.61
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13
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Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression.
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Cancer Metastasis Rev
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2005
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1.58
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14
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Proteases, extracellular matrix, and cancer: a workshop of the path B study section.
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Am J Pathol
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2004
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1.52
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15
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Transcriptional regulation of VEGF-A by the unfolded protein response pathway.
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PLoS One
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2010
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1.52
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16
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Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease.
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Cancer Res
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2005
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1.49
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17
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miR-10b targets Tiam1: implications for Rac activation and carcinoma migration.
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J Biol Chem
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2010
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1.41
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18
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Analysis of integrin beta4 expression in human breast cancer: association with basal-like tumors and prognostic significance.
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Clin Cancer Res
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2008
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1.40
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19
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Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids.
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Curr Biol
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2003
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1.36
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20
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GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation.
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EMBO Mol Med
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2013
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1.33
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21
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Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes.
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Mol Cell Biol
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2004
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1.31
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22
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Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition.
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J Cell Sci
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2009
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1.25
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23
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A role for ADAM12 in breast tumor progression and stromal cell apoptosis.
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Cancer Res
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2005
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1.24
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24
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ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function.
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J Cell Sci
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2003
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1.21
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25
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The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis.
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Exp Cell Res
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2004
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1.16
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26
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ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.
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J Biol Chem
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2002
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1.16
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27
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Role of JNK in mammary gland development and breast cancer.
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Cancer Res
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2011
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1.14
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28
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The alpha6beta4 integrin maintains the survival of human breast carcinoma cells in vivo.
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Cancer Res
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2005
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1.14
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29
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Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2.
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J Biol Chem
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2008
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1.14
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30
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IMP3, a new biomarker to predict progression of cervical intraepithelial neoplasia into invasive cancer.
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Am J Surg Pathol
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2011
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1.13
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31
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The Met receptor and alpha 6 beta 4 integrin can function independently to promote carcinoma invasion.
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J Biol Chem
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2004
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1.06
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32
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VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer.
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Cancer Discov
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2012
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1.06
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33
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The alpha6beta4 integrin can regulate ErbB-3 expression: implications for alpha6beta4 signaling and function.
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Cancer Res
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2007
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1.04
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34
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Intrinsic signaling functions of the beta4 integrin intracellular domain.
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J Biol Chem
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2007
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1.00
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35
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Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells.
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Clin Exp Metastasis
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2003
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0.99
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36
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ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.
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Mol Cancer Res
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2011
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0.99
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37
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Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling.
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J Cell Sci
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2012
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0.98
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38
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Contributions of the alpha6 integrins to breast carcinoma survival and progression.
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Mol Cells
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2004
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0.97
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39
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Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells.
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Cell
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2012
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0.97
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40
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Insulin receptor substrate-2 regulates aerobic glycolysis in mouse mammary tumor cells via glucose transporter 1.
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J Biol Chem
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2008
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0.95
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41
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Epithelial-mesenchymal transition and colorectal cancer: gaining insights into tumor progression using LIM 1863 cells.
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Cells Tissues Organs
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2007
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0.93
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42
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Estrogen receptor β sustains epithelial differentiation by regulating prolyl hydroxylase 2 transcription.
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Proc Natl Acad Sci U S A
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2013
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0.93
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43
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Hypoxia-induced vascular endothelial growth factor transcription and protection from apoptosis are dependent on alpha6beta1 integrin in breast carcinoma cells.
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Cancer Res
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2004
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0.91
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44
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Integrin β4 regulates SPARC protein to promote invasion.
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J Biol Chem
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2012
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0.91
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45
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IMP3 protein promotes chemoresistance in breast cancer cells by regulating breast cancer resistance protein (ABCG2) expression.
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J Biol Chem
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2013
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0.91
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46
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Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB.
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J Biol Chem
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2005
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0.90
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47
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Id2 complexes with the SNAG domain of Snai1 inhibiting Snai1-mediated repression of integrin β4.
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Mol Cell Biol
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2013
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0.89
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48
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Enhancing integrin function by VEGF/neuropilin signaling: implications for tumor biology.
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Cell Adh Migr
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2012
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0.88
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49
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Ras stimulation of E2F activity and a consequent E2F regulation of integrin alpha6beta4 promote the invasion of breast carcinoma cells.
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Cancer Res
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2006
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0.85
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50
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Effects of β4 integrin expression on microRNA patterns in breast cancer.
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Biol Open
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2012
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0.85
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51
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Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland.
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Development
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2011
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0.84
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52
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Expression of the beta 4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells.
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Blood
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2002
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0.76
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