Published in Structure on February 01, 2005
A dual binding mode for RhoGTPases in plexin signalling. PLoS Biol (2011) 1.63
Structural basis of semaphorin-plexin signalling. Nature (2010) 1.58
Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling. Elife (2013) 1.15
Establishing a training set through the visual analysis of crystallization trials. Part I: approximately 150,000 images. Acta Crystallogr D Biol Crystallogr (2008) 1.15
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat Struct Mol Biol (2012) 1.07
Semi-automated microseeding of nanolitre crystallization experiments. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 1.01
Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Angstrom resolution. Protein Sci (2007) 0.98
Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor. Nat Commun (2014) 0.94
Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein. Nat Struct Mol Biol (2015) 0.90
xtalPiMS: a PiMS-based web application for the management and monitoring of crystallization trials. J Struct Biol (2011) 0.81
Preliminary crystallographic analysis of the major capsid protein P2 of the lipid-containing bacteriophage PM2. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.80
Crystallization and preliminary X-ray analysis of mouse RANK and its complex with RANKL. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.76
A rational protocol for the successful crystallization of L-amino-acid oxidase from Bothrops atrox. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol (2006) 6.30
A time- and cost-efficient system for high-level protein production in mammalian cells. Acta Crystallogr D Biol Crystallogr (2006) 5.17
RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteins. Bioinformatics (2005) 4.18
Protein production and purification. Nat Methods (2008) 3.97
Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. Nature (2002) 3.78
A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization. Acta Crystallogr D Biol Crystallogr (2005) 3.75
The crystal structure of human CD1d with and without alpha-galactosylceramide. Nat Immunol (2005) 3.53
A versatile ligation-independent cloning method suitable for high-throughput expression screening applications. Nucleic Acids Res (2007) 3.22
A structural basis for immunodominant human T cell receptor recognition. Nat Immunol (2003) 3.15
Lysine methylation as a routine rescue strategy for protein crystallization. Structure (2006) 3.14
Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy. Acta Crystallogr D Biol Crystallogr (2005) 3.13
What does structure tell us about virus evolution? Curr Opin Struct Biol (2005) 3.02
A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat Struct Mol Biol (2012) 2.81
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. Nat Immunol (2002) 2.70
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2. Nat Struct Mol Biol (2008) 2.58
Insights into assembly from structural analysis of bacteriophage PRD1. Nature (2004) 2.47
Crystal structure of a soluble CD28-Fab complex. Nat Immunol (2005) 2.46
The interaction properties of costimulatory molecules revisited. Immunity (2002) 2.43
A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting. Nature (2006) 2.41
Bluetongue virus VP4 is an RNA-capping assembly line. Nat Struct Mol Biol (2007) 2.40
Glycoprotein structural genomics: solving the glycosylation problem. Structure (2007) 2.40
The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation. J Exp Med (2007) 2.37
Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B*2705. Eur J Immunol (2005) 2.33
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci U S A (2003) 2.33
A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol (2002) 2.31
The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain. Immunity (2008) 2.31
Structural and kinetic basis for heightened immunogenicity of T cell vaccines. J Exp Med (2005) 2.22
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis. Nat Med (2008) 2.19
Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet (2003) 2.16
Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope. Nat Immunol (2006) 2.11
The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines. Nat Struct Mol Biol (2008) 2.09
T cell cross-reactivity and conformational changes during TCR engagement. J Exp Med (2004) 1.99
Structure of the integrin binding fragment from fibrillin-1 gives new insights into microfibril organization. Structure (2004) 1.97
The structure of an RNAi polymerase links RNA silencing and transcription. PLoS Biol (2006) 1.96
In situ macromolecular crystallography using microbeams. Acta Crystallogr D Biol Crystallogr (2012) 1.94
The crystal structure of IgE Fc reveals an asymmetrically bent conformation. Nat Immunol (2002) 1.89
Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2. Structure (2009) 1.89
Structure and functionality in flavivirus NS-proteins: perspectives for drug design. Antiviral Res (2009) 1.87
Insights into the evolution of a complex virus from the crystal structure of vaccinia virus D13. Structure (2011) 1.86
Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation. Cell (2004) 1.86
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance. Nat Immunol (2009) 1.83
Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Nat Struct Mol Biol (2010) 1.80
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein. J Gen Virol (2007) 1.73
Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47. Mol Cell (2008) 1.68
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D. Nat Struct Biol (2003) 1.68
The crystal structure of human CD1b with a bound bacterial glycolipid. J Immunol (2004) 1.64
Structure of a tyrosine phosphatase adhesive interaction reveals a spacer-clamp mechanism. Science (2007) 1.64
A dual binding mode for RhoGTPases in plexin signalling. PLoS Biol (2011) 1.63
HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. J Exp Med (2004) 1.60
Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding. Immunity (2007) 1.60
Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression. J Immunol (2005) 1.60
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science (2011) 1.59
Structural basis of semaphorin-plexin signalling. Nature (2010) 1.58
Structure unifies the viral universe. Annu Rev Biochem (2012) 1.58
Picornavirus uncoating intermediate captured in atomic detail. Nat Commun (2013) 1.57
Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis. PLoS Pathog (2008) 1.57
The nsp9 replicase protein of SARS-coronavirus, structure and functional insights. Structure (2004) 1.55
Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors. J Mol Biol (2009) 1.53
Membrane structure and interactions with protein and DNA in bacteriophage PRD1. Nature (2004) 1.53
Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element. Proc Natl Acad Sci U S A (2010) 1.51
Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling. Dev Cell (2011) 1.50
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity (2009) 1.50
Evolution of viral structure. Theor Popul Biol (2002) 1.48
How baculovirus polyhedra fit square pegs into round holes to robustly package viruses. EMBO J (2009) 1.46
The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion. J Neurosci (2003) 1.46
The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory. Acta Crystallogr D Biol Crystallogr (2011) 1.45