High rate of diversification and reversal among subclones of neoplastically transformed NIH 3T3 clones.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 525657)

Published in Proc Natl Acad Sci U S A on May 01, 1992

Authors

A L Rubin1, A Sneade-Koenig, H Rubin

Author Affiliations

1: Virus Laboratory, University of California, Berkeley 94720.

Articles cited by this

Basis for the acquisition of malignant potential by mouse cells cultivated in vitro. Science (1968) 4.00

Genetic assimilation. Adv Genet (1961) 2.44

Reversion of properties in cells transformed by polyoma virus. Nature (1968) 1.79

Demographic consideration of the cancer problem. Trans N Y Acad Sci (1956) 1.77

Cellular biochemistry of the stepwise development of cancer with chemicals: G. H. A. Clowes memorial lecture. Cancer Res (1984) 1.70

Tumour progression and the nature of cancer. Br J Cancer (1991) 1.69

Effect of interclonal heterogeneity on the progressive, confluence-mediated acquisition of the focus-forming phenotype in NIH-3T3 populations. Cancer Res (1991) 1.63

Cellular adaptation in the origin and development of cancer. Cancer Res (1991) 1.47

Physiological induction and reversal of focus formation and tumorigenicity in NIH 3T3 cells. Proc Natl Acad Sci U S A (1990) 1.42

Relation of spontaneous transformation in cell culture to adaptive growth and clonal heterogeneity. Proc Natl Acad Sci U S A (1990) 1.39

Cancer as a dynamic developmental disorder. Cancer Res (1985) 1.35

Genetic convergence and divergence in tumor progression. Cancer Res (1988) 1.31

Progressive state selection of cells in low serum promotes high density growth and neoplastic transformation in NIH 3T3 cells. Cancer Res (1990) 1.08

Adaptive evolution of degrees and kinds of neoplastic transformation in cell culture. Proc Natl Acad Sci U S A (1992) 1.00

Reversion of the transformed phenotype to the parental phenotype by subcultivation of X-ray-transformed C3H/10T1/2 cells at low cell density. Int J Cancer (1979) 0.99

Suppression of transformation by and growth adaptation to low concentrations of glutamine in NIH-3T3 cells. Cancer Res (1990) 0.93

Induction of transformation in NIH3T3 cells by moderate growth constraint: evidence that neoplasia is driven by adaptational change. Carcinogenesis (1991) 0.89

High frequency of tumour cell reversion to non-tumorigenic phenotype. Eur J Cancer (1992) 0.89

Articles by these authors

The nucleic acid of the Bryan strain of Rous sarcoma virus: purification of the virus and isolation of the nucleic acid. Proc Natl Acad Sci U S A (1965) 4.95

Effects of local cell concentrations upon the growth of chick embryo cells in tissue culture. Exp Cell Res (1968) 3.94

Density dependent inhibition of cell growth in culture. Nature (1967) 3.51

Release from density dependent growth inhibition by proteolytic enzymes. Nature (1970) 3.20

Temperature-dependent alterations in sugar transport in cells infected by a temperature-sensitive mutant of Rous sarcoma virus. Proc Natl Acad Sci U S A (1971) 2.83

The stringent response of Mycobacterium tuberculosis is required for long-term survival. J Bacteriol (2000) 2.80

Behavioral engineering: postural control by a portable operant apparatus. J Appl Behav Anal (1968) 2.65

Intensive care unit telemedicine: alternate paradigm for providing continuous intensivist care. Crit Care Med (2000) 2.50

Calcium protects DNase I from proteinase K: a new method for the removal of contaminating RNase from DNase I. Anal Biochem (1980) 2.49

The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. I. Establishment of interference. Virology (1966) 2.22

The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV of cells under conditions of interference. Virology (1966) 2.11

Uridine transport and RNA synthesis in growing and in density-inhibited animal cells. J Cell Physiol (1971) 1.97

Stimulation of glucose transport in cultures of density-inhibited chick embryo cells. Proc Natl Acad Sci U S A (1971) 1.91

A substance in conditioned medium which enhances the growth of small numbers of chick embryo cells. Exp Cell Res (1966) 1.85

Inhibition of DNA synthesis in animal cells by ethylene diamine tetraacetate, and its reversal by zinc. Proc Natl Acad Sci U S A (1972) 1.78

Role of small t antigen in the acute transforming activity of SV40. Cell (1982) 1.76

Cost-effectiveness of HA-1A monoclonal antibody for gram-negative sepsis. Economic assessment of a new therapeutic agent. JAMA (1991) 1.71

Central role for magnesium in coordinate control of metabolism and growth in animal cells. Proc Natl Acad Sci U S A (1975) 1.70

pH and population density in the regulation of animal cell multiplication. J Cell Biol (1971) 1.67

Effect of interclonal heterogeneity on the progressive, confluence-mediated acquisition of the focus-forming phenotype in NIH-3T3 populations. Cancer Res (1991) 1.63

Patterns of glucose metabolism in normal and virus-transformed chick cells in tissue culture. J Natl Cancer Inst (1972) 1.62

Inhibition of Hageman factor activation. J Clin Invest (1968) 1.58

Malaria and the cell cycle. Parasitol Today (1996) 1.56

Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J Bacteriol (2001) 1.54

Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis. Gene (1999) 1.47

Cellular adaptation in the origin and development of cancer. Cancer Res (1991) 1.47

Specific interference among strains of Newcastle disease virus. 3. Mechanisms of interference. Virology (1968) 1.42

Physiological induction and reversal of focus formation and tumorigenicity in NIH 3T3 cells. Proc Natl Acad Sci U S A (1990) 1.42

Differential regulation of opposing RelMtb activities by the aminoacylation state of a tRNA.ribosome.mRNA.RelMtb complex. Biochemistry (2000) 1.40

Relation of spontaneous transformation in cell culture to adaptive growth and clonal heterogeneity. Proc Natl Acad Sci U S A (1990) 1.39

Overgrowth stimulating factor released from Rous sarcoma cells. Science (1970) 1.39

Early release of growth inhibition in cells infected with Rous sarcoma virus. Proc Natl Acad Sci U S A (1968) 1.38

Chronic cystitis due to Cokeromyces recurvatus: a case report. J Infect Dis (1987) 1.36

Cancer as a dynamic developmental disorder. Cancer Res (1985) 1.35

The inhibition of chick embryo cell growth by medium obtained from cultures of Rous sarcoma cells. Exp Cell Res (1966) 1.28

Magnesium deprivation reproduces the coordinate effects of serum removal or cortisol addition on transport and metabolism in chick embryo fibroblasts. J Cell Physiol (1976) 1.27

Activation of phosphofructokinase by stimulants of cell multiplication. Nat New Biol (1973) 1.26

Observations following Corynebacterium parvum administration to patients with advanced malignancy. a phase I study. Cancer (1976) 1.25

Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop. Nat Struct Biol (1994) 1.23

Mutual potentiation by magnesium and calcium of growth in animal cells. Proc Natl Acad Sci U S A (1976) 1.21

Early origin and pervasiveness of cellular heterogeneity in some malignant transformations. Proc Natl Acad Sci U S A (1984) 1.19

Complexes of inorganic pyrophosphate, orthophosphate, and calcium as stimulants of 3T3 cell multiplication. Proc Natl Acad Sci U S A (1977) 1.16

Sugar transport in normal and Rous sarcoma virus-transformed chick-embryo fibroblasts. Proc Natl Acad Sci U S A (1973) 1.15

Identification and initial characterization of a new low-molecular-weight virus-encoded T antigen in a line of simian virus 40-transformed cells. J Virol (1980) 1.11

Specific interference among strains of Newcastle disease virus. II. Comparison of interference by active and inactive virus. Virology (1968) 1.10

Growth regulation, reverse transformation, and adaptability of 3T3 cells in decreased Mg2+ concentration. Proc Natl Acad Sci U S A (1981) 1.09

Progressive state selection of cells in low serum promotes high density growth and neoplastic transformation in NIH 3T3 cells. Cancer Res (1990) 1.08

Early cellular responses to diverse growth stimuli independent of protein and RNA synthesis. J Cell Physiol (1975) 1.07

Electrical coupling: low resistance junctions between mitotic and interphase fibroblasts in tissue culture. Science (1970) 1.07

The carboxyl terminus heptapeptide of the R2 subunit of mammalian ribonucleotide reductase inhibits enzyme activity and can be used to purify the R1 subunit. FEBS Lett (1990) 1.07

Effects of cell adhesion of the substratum on the growth of chick embryo fibroblasts. Exp Cell Res (1974) 1.07

Leakage as the source of overgrowth stimulating activity in Rous sarcoma transformed cultures. Exp Cell Res (1971) 1.06

Type II NADH: menaquinone oxidoreductase of Mycobacterium tuberculosis. Infect Disord Drug Targets (2007) 1.06

Mutations and oncogenes--cause or effect. Nature (1984) 1.06

Glucose utilization, pH reduction and density dependent inhibition in cultures of chick embryo fibroblasts. J Cell Physiol (1975) 1.05

Early "step-down" transfer of low-risk patients with chest pain. A controlled interventional trial. Ann Intern Med (1990) 1.05

Stimulation of DNA synthesis and 2-deoxy-D-glucose transport in chick embryo cultures by excessive metal concentrations and by a carcinogenic hydrocarbon. J Cell Physiol (1973) 1.04

Developing and implementing measures of quality of care in the intensive care unit. Curr Opin Crit Care (2001) 1.04

Correlated effects of external magnesium on cation content and DNA synthesis in culture chicken embryo fibroblasts. J Cell Physiol (1977) 1.02

Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors. J Biol Chem (1989) 1.01

Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization. Gene Ther (2008) 1.01

Direct wet mounts versus concentration for routine parasitological examination: are both necessary? Am J Clin Pathol (1988) 1.01

Studies on the nature of serum stimulation of proliferation in cell culture. In Vitro (1972) 1.00

Radiation studies of avian tumor viruses and of Newcastle disease virus. Virology (1966) 1.00

Rous sarcoma virus production from clones of nontransformed chick embryo fibroblasts. Virology (1966) 1.00

Chemoattractant-mediated increases in cGMP induce changes in Dictyostelium myosin II heavy chain-specific protein kinase C activities. J Cell Biol (1996) 0.99

Coordinate control of collagen synthesis and cell growth in chick embryo fibroblasts and the effect of viral transformation on collagen synthesis. J Cell Physiol (1977) 0.99

Inhibition of DNA synthesis in chick embryo cultures by deprivation of either serum or zinc. J Cell Biol (1973) 0.98

Overgrowth-stimulating activity of disrupted chick embryo cells and cells infected with Rous sarcoma virus. Proc Natl Acad Sci U S A (1970) 0.98

The control of neutrophil chemotaxis by inhibitors of cathepsin G and chymotrypsin. J Biol Chem (1995) 0.98

Paroxysmal nocturnal hemoglobinuria with renal failure. JAMA (1971) 0.97

Increased hyaluronic acid production on stimulation of DNA synthesis in chick embryo fibroblasts. Nature (1975) 0.97

Is somatic mutation the major mechanism of malignant transformation? J Natl Cancer Inst (1980) 0.97

Acute calcific quadriceps tendinitis. South Med J (1980) 0.96

Inhibition of human neutrophil superoxide generation by alpha 1-antichymotrypsin. J Immunol (1991) 0.96

Reaction of human chymase with reactive site variants of alpha 1-antichymotrypsin. Modulation of inhibitor versus substrate properties. J Biol Chem (1993) 0.96

Distortion of the active site of chymotrypsin complexed with a serpin. Biochemistry (1996) 0.95

Subcellular localization of glyoxylate cycle enzymes in Ascaris suum larvae. J Cell Biol (1976) 0.95

Heritable variations in growth potential and morphology within a clone of Balb/3T3 cells and their relation to tumor formation. J Natl Cancer Inst (1983) 0.94

Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis. Biochemistry (1996) 0.94

Perturbation of red cell membrane structure during intracellular maturation of Plasmodium falciparum. Science (1986) 0.93

Suppression of transformation by and growth adaptation to low concentrations of glutamine in NIH-3T3 cells. Cancer Res (1990) 0.93

Predictors of patient-reported physical and mental health 6 months after percutaneous coronary revascularization. Am Heart J (1999) 0.93

R2 C-terminal peptide inhibition of mammalian and yeast ribonucleotide reductase. J Med Chem (1993) 0.93

Characterization of two genes encoding the Mycobacterium tuberculosis ribonucleotide reductase small subunit. J Bacteriol (1997) 0.93

Armadillo exposure and Hansen's disease: an epidemiologic survey in southern Texas. J Am Acad Dermatol (2000) 0.90

Reversible alterations in the mitotic cycle of chick embryo cells in various states of growth regulation. J Cell Physiol (1975) 0.90

Soybean Bowman-Birk protease inhibitor is a highly effective inhibitor of human mast cell chymase. Arch Biochem Biophys (1997) 0.90

The exchange of phospholipids between cultured chick embryo fibroblasts and their growth medium. Exp Cell Res (1969) 0.90

Sequential changes in serum iron and ferritin in patients undergoing high-dose chemotherapy and radiation with autologous bone marrow transplantation: possible implications for treatment related toxicity. Free Radic Biol Med (1995) 0.90

Increase in the size of chick embryo cells upon cultivation in serum-containing medium. Dev Biol (1968) 0.90

Evidence that intracellular magnesium is present in cells at a regulatory concentration for protein synthesis. Proc Natl Acad Sci U S A (1985) 0.89

The tyrosyl free radical of recombinant ribonucleotide reductase from Mycobacterium tuberculosis is located in a rigid hydrophobic pocket. Biochemistry (1998) 0.89

Induction of transformation in NIH3T3 cells by moderate growth constraint: evidence that neoplasia is driven by adaptational change. Carcinogenesis (1991) 0.89

pH, serum and Zn++ in the regulation of DNA synthesis in cultures of chick embryo cells. J Cell Physiol (1973) 0.89

Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue. Biol Chem (2000) 0.88

Object naming ability of adults with written language difficulties. Ann Dyslexia (1992) 0.88

Antichymotrypsin interaction with chymotrypsin. Partitioning of the complex. J Biol Chem (1993) 0.88

Further observations on the inhibition of tumor growth by Corynebacterium parvum with cyclophosphamide. I. Variation in administration of both agents. J Natl Cancer Inst (1975) 0.87