PubRank

Jenny P-Y Ting

Author PubWeight™ 151.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol 2011 6.53
2 The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 2009 6.37
3 The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 2011 5.73
4 Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol 2008 4.60
5 NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 2008 4.55
6 The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med 2010 4.37
7 Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host Microbe 2007 3.52
8 DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci U S A 2006 3.41
9 Novel role of PKR in inflammasome activation and HMGB1 release. Nature 2012 3.13
10 Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes Dev 2008 2.89
11 A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation? Nat Immunol 2012 2.59
12 Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. J Immunol 2003 2.48
13 NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. J Immunol 2009 2.39
14 The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. J Biol Chem 2005 2.21
15 Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. J Immunol 2002 2.18
16 CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions. Nat Immunol 2003 2.13
17 Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J Immunol 2009 2.09
18 NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity 2012 2.07
19 Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity 2013 2.02
20 Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. J Immunol 2007 1.97
21 NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J Immunol 2010 1.73
22 Epigenetic regulation of MHC-II and CIITA genes. Trends Immunol 2006 1.73
23 MAVS-mediated apoptosis and its inhibition by viral proteins. PLoS One 2009 1.67
24 Cutting edge: NLRC5-dependent activation of the inflammasome. J Immunol 2010 1.66
25 Criteria for effective design, construction, and gene knockdown by shRNA vectors. BMC Biotechnol 2006 1.60
26 Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol 2010 1.59
27 De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis. J Immunol 2002 1.58
28 Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses. J Virol 2006 1.57
29 Chromosomal clustering of genes controlled by the aire transcription factor. Proc Natl Acad Sci U S A 2005 1.49
30 TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. PLoS One 2012 1.48
31 Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner. Blood 2011 1.48
32 Inflammasome inhibition as a pathogenic stealth mechanism. Cell Host Microbe 2010 1.47
33 The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nat Immunol 2012 1.45
34 Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. PLoS One 2010 1.44
35 Regulation of mitochondrial antiviral signaling pathways. Immunity 2008 1.44
36 The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity 2012 1.44
37 The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18. J Neurosci 2010 1.37
38 CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function. J Biol Chem 2005 1.35
39 NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. J Immunol 2012 1.34
40 Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. Cancer Res 2003 1.34
41 Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes. J Immunol 2003 1.33
42 The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response. Infect Immun 2006 1.30
43 ATP binding by monarch-1/NLRP12 is critical for its inhibitory function. Mol Cell Biol 2007 1.25
44 C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9. Am J Pathol 2008 1.22
45 Analysis of NLRP3 in the development of allergic airway disease in mice. J Immunol 2012 1.18
46 Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells. PLoS Pathog 2013 1.18
47 Enhancement of CIITA transcriptional function by ubiquitin. Nat Immunol 2003 1.18
48 Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. J Neurosci 2003 1.18
49 The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. Cancer Res 2010 1.18
50 Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines. Curr Opin Immunol 2011 1.17
51 Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation. Mol Cell Biol 2003 1.16
52 Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes. Curr Opin Immunol 2005 1.16
53 Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. J Immunol 2013 1.15
54 Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination. Cancer Treat Rev 2006 1.14
55 Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm. J Exp Med 2010 1.12
56 Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proc Natl Acad Sci U S A 2005 1.08
57 Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation. J Biol Chem 2011 1.04
58 The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription. Mol Immunol 2008 1.02
59 Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins. J Biol Chem 2012 1.01
60 Cryopyrin: in from the cold. Immunity 2006 0.98
61 Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors. J Immunol 2002 0.97
62 Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase. J Immunol 2007 0.97
63 Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination. Glia 2005 0.97
64 Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. EMBO Rep 2013 0.96
65 Serine residues 286, 288, and 293 within the CIITA: a mechanism for down-regulating CIITA activity through phosphorylation. J Immunol 2004 0.95
66 Plexin-D1 is a novel regulator of germinal centers and humoral immune responses. J Immunol 2011 0.94
67 Cuprizone induces similar demyelination in male and female C57BL/6 mice and results in disruption of the estrous cycle. J Neurosci Res 2010 0.94
68 Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases. J Immunol 2009 0.93
69 CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses. Proc Am Thorac Soc 2007 0.93
70 Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells. J Immunol 2006 0.92
71 A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites. Eur J Immunol 2004 0.92
72 Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. Clin Cancer Res 2002 0.92
73 Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses. Proc Natl Acad Sci U S A 2008 0.92
74 The protective role of nitric oxide in a neurotoxicant-induced demyelinating model. J Immunol 2002 0.91
75 Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. J Neurosci 2007 0.90
76 Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor. Cancer Res 2003 0.90
77 DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB. J Biol Chem 2010 0.90
78 Regulation and specificity of MHC2TA promoter usage in human primary T lymphocytes and cell line. J Immunol 2002 0.90
79 Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels. PLoS One 2012 0.88
80 Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis. J Biol Chem 2008 0.87
81 MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma. J Exp Clin Cancer Res 2014 0.87
82 Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues. Glia 2006 0.86
83 Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production. PLoS One 2012 0.86
84 MyD88 provides a protective role in long-term radiation-induced lung injury. Int J Radiat Biol 2012 0.85
85 NLRs and the dangers of pollution and aging. Nat Immunol 2008 0.85
86 The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation. J Biol Chem 2013 0.84
87 TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model. J Neuroimmunol 2008 0.84
88 Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. PLoS One 2011 0.83
89 Toward a molecular pathogenic pathway for Yersinia pestis YopM. Front Cell Infect Microbiol 2012 0.83
90 Characterization of NLRP12 during the development of allergic airway disease in mice. PLoS One 2012 0.82
91 Downregulation of immune signaling genes in patients with large surface burn injury. J Burn Care Res 2007 0.81
92 Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription. Exp Cell Res 2006 0.81
93 Prolonged survival of class II transactivator-deficient cardiac allografts. Transplantation 2002 0.80
94 The evolving role of semaphorins and plexins in the immune system: Plexin-A1 regulation of dendritic cell function. Immunol Res 2008 0.80
95 Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation. Hum Immunol 2002 0.80
96 NLRX1 has a tail to tell. Immunity 2012 0.78
97 Comparison of Abeta(b-/-), H2-DM(-), and CIITA(-/-) in second-set skin allograft rejection. J Surg Res 2002 0.78
98 Agitation by suffocation: how hypoxia activates innate immunity via the Warburg effect. Cell Metab 2013 0.76
99 17beta-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss. Neurobiol Dis 2010 0.76
100 Erratum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nat Immunol 2017 0.75
101 Corrigendum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nat Immunol 2017 0.75