Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
2
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
3
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
4
|
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
|
Nat Genet
|
2008
|
15.94
|
5
|
Genome-wide association study identifies eight loci associated with blood pressure.
|
Nat Genet
|
2009
|
12.44
|
6
|
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
Nat Genet
|
2008
|
12.07
|
7
|
Variants in MTNR1B influence fasting glucose levels.
|
Nat Genet
|
2008
|
10.85
|
8
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
9
|
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
|
Nat Genet
|
2010
|
6.49
|
10
|
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
|
Nat Genet
|
2009
|
5.43
|
11
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
12
|
Genome-wide association study identifies five loci associated with lung function.
|
Nat Genet
|
2009
|
4.10
|
13
|
Identification of seven loci affecting mean telomere length and their association with disease.
|
Nat Genet
|
2013
|
3.87
|
14
|
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.
|
Diabetes
|
2008
|
3.76
|
15
|
Genetic loci influencing kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
3.75
|
16
|
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.
|
Circulation
|
2011
|
3.68
|
17
|
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.
|
Nature
|
2012
|
3.41
|
18
|
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
|
Nat Genet
|
2011
|
3.40
|
19
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
|
Nat Genet
|
2010
|
3.37
|
20
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
21
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
22
|
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
|
Nat Genet
|
2011
|
3.18
|
23
|
New gene functions in megakaryopoiesis and platelet formation.
|
Nature
|
2011
|
3.14
|
24
|
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
Nat Genet
|
2011
|
3.03
|
25
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
26
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
27
|
Seventy-five genetic loci influencing the human red blood cell.
|
Nature
|
2012
|
2.77
|
28
|
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.
|
PLoS Med
|
2013
|
2.73
|
29
|
A genome-wide association meta-analysis identifies new childhood obesity loci.
|
Nat Genet
|
2012
|
2.60
|
30
|
Elevated blood pressure in pregnancy and subsequent chronic disease risk.
|
Circulation
|
2013
|
2.33
|
31
|
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
|
Nat Genet
|
2010
|
2.30
|
32
|
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
|
Proc Natl Acad Sci U S A
|
2011
|
2.01
|
33
|
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
|
Nat Genet
|
2012
|
1.90
|
34
|
Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.
|
PLoS Genet
|
2009
|
1.89
|
35
|
Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.
|
PLoS Genet
|
2011
|
1.82
|
36
|
Long-term leisure-time physical activity and serum metabolome.
|
Circulation
|
2012
|
1.81
|
37
|
Immediate complications after medical compared with surgical termination of pregnancy.
|
Obstet Gynecol
|
2009
|
1.77
|
38
|
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
|
Nat Genet
|
2013
|
1.72
|
39
|
Relationship between birthweight and blood lipid concentrations in later life: evidence from the existing literature.
|
Int J Epidemiol
|
2003
|
1.72
|
40
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
41
|
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.
|
PLoS Med
|
2013
|
1.70
|
42
|
Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study.
|
J Clin Endocrinol Metab
|
2008
|
1.69
|
43
|
Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.
|
J Mol Med (Berl)
|
2009
|
1.62
|
44
|
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
|
Circ Cardiovasc Genet
|
2012
|
1.60
|
45
|
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
|
Nat Genet
|
2011
|
1.60
|
46
|
Type 2 diabetes risk alleles are associated with reduced size at birth.
|
Diabetes
|
2009
|
1.58
|
47
|
Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.
|
PLoS Genet
|
2010
|
1.40
|
48
|
Thyroid dysfunction and autoantibodies during pregnancy as predictive factors of pregnancy complications and maternal morbidity in later life.
|
J Clin Endocrinol Metab
|
2010
|
1.38
|
49
|
Distinct variants at LIN28B influence growth in height from birth to adulthood.
|
Am J Hum Genet
|
2010
|
1.37
|
50
|
Early growth and adult respiratory function in men and women followed from the fetal period to adulthood.
|
Thorax
|
2006
|
1.36
|
51
|
Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts.
|
PLoS One
|
2012
|
1.35
|
52
|
Size at birth, weight gain over the life course, and low-grade inflammation in young adulthood: northern Finland 1966 Birth Cohort study.
|
Eur Heart J
|
2008
|
1.32
|
53
|
Risks of overweight and abdominal obesity at age 16 years associated with prenatal exposures to maternal prepregnancy overweight and gestational diabetes mellitus.
|
Diabetes Care
|
2010
|
1.30
|
54
|
Metabolic cardiovascular disease risk factors in women with self-reported symptoms of oligomenorrhea and/or hirsutism: Northern Finland Birth Cohort 1966 Study.
|
J Clin Endocrinol Metab
|
2004
|
1.30
|
55
|
The effect of freezing, thawing, and short- and long-term storage on serum thyrotropin, thyroid hormones, and thyroid autoantibodies: implications for analyzing samples stored in serum banks.
|
Clin Chem
|
2007
|
1.29
|
56
|
Relation of immediate postnatal growth with obesity and related metabolic risk factors in adulthood: the northern Finland birth cohort 1966 study.
|
Am J Epidemiol
|
2010
|
1.26
|
57
|
Adolescent manifestations of metabolic syndrome among children born to women with gestational diabetes in a general-population birth cohort.
|
Am J Epidemiol
|
2009
|
1.26
|
58
|
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.
|
PLoS Genet
|
2012
|
1.23
|
59
|
Hormonal profile of women with self-reported symptoms of oligomenorrhea and/or hirsutism: Northern Finland birth cohort 1966 study.
|
J Clin Endocrinol Metab
|
2003
|
1.21
|
60
|
Maintenance of genetic variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding.
|
Evolution
|
2012
|
1.21
|
61
|
TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood.
|
Biol Psychiatry
|
2010
|
1.21
|
62
|
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
|
Hum Mol Genet
|
2013
|
1.19
|
63
|
Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
|
Hum Mol Genet
|
2013
|
1.17
|
64
|
Evidence of inbreeding depression on human height.
|
PLoS Genet
|
2012
|
1.16
|
65
|
Early pregnancy reference intervals of thyroid hormone concentrations in a thyroid antibody-negative pregnant population.
|
Thyroid
|
2011
|
1.14
|
66
|
Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci.
|
Hum Mol Genet
|
2011
|
1.13
|
67
|
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.
|
PLoS One
|
2011
|
1.13
|
68
|
Comparison of metabolic and inflammatory outcomes in women who used oral contraceptives and the levonorgestrel-releasing intrauterine device in a general population.
|
Am J Obstet Gynecol
|
2008
|
1.10
|
69
|
Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene.
|
PLoS One
|
2012
|
1.05
|
70
|
Pubertal timing and growth influences cardiometabolic risk factors in adult males and females.
|
Diabetes Care
|
2012
|
1.04
|
71
|
Cardiometabolic risk factors in young adults who were born preterm.
|
Am J Epidemiol
|
2015
|
1.04
|
72
|
Associations between pre-pregnancy obesity and asthma symptoms in adolescents.
|
J Epidemiol Community Health
|
2011
|
1.04
|
73
|
Life-course analysis of a fat mass and obesity-associated (FTO) gene variant and body mass index in the Northern Finland Birth Cohort 1966 using structural equation modeling.
|
Am J Epidemiol
|
2010
|
1.02
|
74
|
Prepregnancy overweight and gestational diabetes as determinants of subsequent diabetes and hypertension after 20-year follow-up.
|
J Clin Endocrinol Metab
|
2009
|
1.02
|
75
|
Large-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone.
|
J Clin Endocrinol Metab
|
2004
|
1.01
|
76
|
Does in utero exposure to synthetic glucocorticoids influence birthweight, head circumference and birth length? A systematic review of current evidence in humans.
|
Paediatr Perinat Epidemiol
|
2010
|
0.99
|
77
|
Low-grade, systemic inflammation in adolescents: association with early-life factors, gender, and lifestyle.
|
Am J Epidemiol
|
2009
|
0.99
|
78
|
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.
|
PLoS One
|
2012
|
0.99
|
79
|
Analysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits.
|
J Clin Endocrinol Metab
|
2005
|
0.96
|
80
|
Smoking and early pregnancy thyroid hormone and anti-thyroid antibody levels in euthyroid mothers of the Northern Finland Birth Cohort 1986.
|
Thyroid
|
2012
|
0.95
|
81
|
Frequency and risk factors for repeat abortions after surgical compared with medical termination of pregnancy.
|
Obstet Gynecol
|
2009
|
0.94
|
82
|
Comprehensive maternal serum proteomic profiles of preclinical and clinical preeclampsia.
|
J Proteome Res
|
2010
|
0.91
|
83
|
Variation at the insulin gene VNTR (variable number tandem repeat) polymorphism and early growth: studies in a large Finnish birth cohort.
|
Diabetes
|
2004
|
0.91
|
84
|
European lactase persistence genotype shows evidence of association with increase in body mass index.
|
Hum Mol Genet
|
2009
|
0.91
|
85
|
Offspring's blood pressure and metabolic phenotype after exposure to gestational hypertension in utero.
|
Eur J Epidemiol
|
2013
|
0.90
|
86
|
Glucocorticoid receptor (NR3C1) gene polymorphisms and onset of alcohol abuse in adolescents.
|
Addict Biol
|
2010
|
0.90
|
87
|
Age at menarche and depression at the age of 31 years: findings from the Northern Finland 1966 Birth Cohort Study.
|
J Psychosom Res
|
2004
|
0.89
|
88
|
Epilepsy in the northern Finland birth cohort 1966 with special reference to fertility.
|
Epilepsy Behav
|
2008
|
0.86
|
89
|
Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure.
|
PLoS Genet
|
2012
|
0.85
|
90
|
Early-life origins of schizotypal traits in adulthood.
|
Br J Psychiatry
|
2009
|
0.85
|
91
|
The impact of gestational thyroid hormone concentrations on ADHD symptoms of the child.
|
J Clin Endocrinol Metab
|
2013
|
0.83
|
92
|
Weight at birth and infancy in relation to adult leukocyte count: a population-based study of 5619 men and women followed from the fetal period to adulthood.
|
J Clin Endocrinol Metab
|
2009
|
0.83
|
93
|
Detailed analysis of variation at and around mitochondrial position 16189 in a large Finnish cohort reveals no significant associations with early growth or metabolic phenotypes at age 31 years.
|
J Clin Endocrinol Metab
|
2007
|
0.83
|
94
|
Prediction of adolescent and adult adiposity outcomes from early life anthropometrics.
|
Obesity (Silver Spring)
|
2014
|
0.83
|
95
|
Chlamydia antibodies and self-reported symptoms of oligo-amenorrhea and hirsutism: a new etiologic factor in polycystic ovary syndrome?
|
Fertil Steril
|
2010
|
0.83
|
96
|
Maternal Hb during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years.
|
Br J Nutr
|
2010
|
0.82
|
97
|
Is initiation of smoking associated with the prodromal phase of schizophrenia?
|
J Psychiatry Neurosci
|
2005
|
0.82
|
98
|
Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.
|
Eur J Hum Genet
|
2007
|
0.81
|
99
|
Birth measures and depression at age 31 years: the Northern Finland 1966 Birth Cohort Study.
|
Psychiatry Res
|
2008
|
0.81
|
100
|
Maternal serum Chlamydia pneumoniae antibodies and CRP levels in women with preeclampsia and gestational hypertension.
|
Hypertens Pregnancy
|
2008
|
0.80
|
101
|
Exposure to obstetric complications in relation to subsequent psychiatric disorders of adolescent inpatients: specific focus on gender differences.
|
Psychopathology
|
2012
|
0.79
|
102
|
Serum C-reactive protein and Chlamydia trachomatis antibodies in preterm delivery.
|
Obstet Gynecol
|
2005
|
0.79
|
103
|
Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.
|
Circ Cardiovasc Genet
|
2012
|
0.79
|
104
|
High-dose vitamin D supplements are not associated with linear growth in a large Finnish cohort.
|
J Nutr
|
2011
|
0.78
|
105
|
Infant locomotive development and its association with adult blood pressure.
|
Eur J Pediatr
|
2014
|
0.77
|
106
|
Impact of the dopamine receptor gene family on temperament traits in a population-based birth cohort.
|
Am J Med Genet B Neuropsychiatr Genet
|
2009
|
0.77
|
107
|
Maternal thyroid dysfunction during pregnancy and thyroid function of her child in adolescence.
|
J Clin Endocrinol Metab
|
2013
|
0.77
|
108
|
Preeclampsia, gestational hypertension and subsequent hypothyroidism.
|
Pregnancy Hypertens
|
2012
|
0.77
|
109
|
Ante- and perinatal circumstances and risk of attempted suicides and suicides in offspring: the Northern Finland birth cohort 1966 study.
|
Soc Psychiatry Psychiatr Epidemiol
|
2012
|
0.77
|
110
|
Maternal preeclampsia and bone mineral density of the adult offspring.
|
Am J Obstet Gynecol
|
2013
|
0.77
|
111
|
Maternal hypertensive disorders during pregnancy and mild cognitive limitations in the offspring.
|
Paediatr Perinat Epidemiol
|
2012
|
0.77
|
112
|
The interplay of variants near LEKR and CCNL1 and social stress in relation to birth size.
|
PLoS One
|
2012
|
0.76
|
113
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
114
|
Metabolic and reproductive characteristics of first-degree relatives of women with self-reported oligo-amenorrhoea and hirsutism.
|
Gynecol Endocrinol
|
2010
|
0.75
|
115
|
PP083. Maternal pre-eclampsia and bone mineral density of the adult offspring.
|
Pregnancy Hypertens
|
2013
|
0.75
|