|
1
|
Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons.
|
J Neurosci
|
2005
|
2.96
|
|
2
|
Engineering GPCR signaling pathways with RASSLs.
|
Nat Methods
|
2008
|
2.29
|
|
3
|
Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy.
|
Brain
|
2007
|
1.83
|
|
4
|
Systems medicine and integrated care to combat chronic noncommunicable diseases.
|
Genome Med
|
2011
|
1.78
|
|
5
|
Plant insecticide L-canavanine repels Drosophila via the insect orphan GPCR DmX.
|
PLoS Biol
|
2009
|
1.60
|
|
6
|
Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis.
|
Brain Res
|
2002
|
1.53
|
|
7
|
A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL).
|
J Biol Chem
|
2002
|
1.42
|
|
8
|
New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.
|
J Cell Sci
|
2004
|
1.40
|
|
9
|
Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons.
|
Proc Natl Acad Sci U S A
|
2007
|
1.40
|
|
10
|
GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells.
|
J Biol Chem
|
2009
|
1.36
|
|
11
|
Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approach.
|
EMBO J
|
2002
|
1.35
|
|
12
|
GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation.
|
Trends Pharmacol Sci
|
2007
|
1.33
|
|
13
|
Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila.
|
J Neurosci
|
2004
|
1.32
|
|
14
|
Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors.
|
Mol Pharmacol
|
2009
|
1.29
|
|
15
|
The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins.
|
J Biol Chem
|
2004
|
1.25
|
|
16
|
G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient.
|
J Biol Chem
|
2011
|
1.21
|
|
17
|
Epileptiform activity induces vascular remodeling and zonula occludens 1 downregulation in organotypic hippocampal cultures: role of VEGF signaling pathways.
|
J Neurosci
|
2011
|
1.19
|
|
18
|
Proteomic analysis of astrocytic secretion in the mouse. Comparison with the cerebrospinal fluid proteome.
|
J Biol Chem
|
2003
|
1.18
|
|
19
|
Epac mediates PACAP-dependent long-term depression in the hippocampus.
|
J Physiol
|
2008
|
1.17
|
|
20
|
Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons.
|
Mol Cell Neurosci
|
2002
|
1.15
|
|
21
|
Increased number of neural progenitors in human temporal lobe epilepsy.
|
Neurobiol Dis
|
2005
|
1.12
|
|
22
|
Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors.
|
J Biol Chem
|
2008
|
1.11
|
|
23
|
Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice.
|
J Neurosci
|
2004
|
1.10
|
|
24
|
Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction.
|
Mol Pharmacol
|
2007
|
1.10
|
|
25
|
Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.
|
Mol Biol Cell
|
2008
|
1.08
|
|
26
|
Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer.
|
Biophys J
|
2007
|
1.08
|
|
27
|
Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens.
|
Proc Natl Acad Sci U S A
|
2007
|
1.06
|
|
28
|
Akt mediates the anti-apoptotic effect of NMDA but not that induced by potassium depolarization in cultured cerebellar granule cells.
|
Eur J Neurosci
|
2002
|
1.03
|
|
29
|
PICK1 uncoupling from mGluR7a causes absence-like seizures.
|
Nat Neurosci
|
2008
|
1.03
|
|
30
|
Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells.
|
J Biol Chem
|
2002
|
1.01
|
|
31
|
The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology.
|
J Neurosci
|
2004
|
1.00
|
|
32
|
Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability.
|
Mol Biol Cell
|
2006
|
1.00
|
|
33
|
A model for the functioning of family 3 GPCRs.
|
Trends Pharmacol Sci
|
2002
|
0.99
|
|
34
|
Metabotropic glutamate receptor 2/3-dependent long-term depression in the nucleus accumbens is blocked in morphine withdrawn mice.
|
Eur J Neurosci
|
2002
|
0.99
|
|
35
|
Muscle dystroglycan organizes the postsynapse and regulates presynaptic neurotransmitter release at the Drosophila neuromuscular junction.
|
PLoS One
|
2008
|
0.99
|
|
36
|
The proteomic analysis of mouse choroid plexus secretome reveals a high protein secretion capacity of choroidal epithelial cells.
|
Proteomics
|
2006
|
0.97
|
|
37
|
5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.
|
EMBO Mol Med
|
2012
|
0.95
|
|
38
|
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.
|
EMBO J
|
2009
|
0.95
|
|
39
|
Enhanced detection of CNS cell secretome in plasma protein-depleted cerebrospinal fluid.
|
J Proteome Res
|
2008
|
0.95
|
|
40
|
Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse.
|
Eur J Neurosci
|
2006
|
0.94
|
|
41
|
Homer1a-dependent crosstalk between NMDA and metabotropic glutamate receptors in mouse neurons.
|
PLoS One
|
2010
|
0.94
|
|
42
|
Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements.
|
J Biol Chem
|
2005
|
0.92
|
|
43
|
Dynamic remodeling of scaffold interactions in dendritic spines controls synaptic excitability.
|
J Cell Biol
|
2012
|
0.92
|
|
44
|
MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channels.
|
J Neurochem
|
2006
|
0.91
|
|
45
|
Alzheimer culprits: cellular crossroads and interplay.
|
Cell Signal
|
2012
|
0.91
|
|
46
|
A 5-HT4 receptor transmembrane network implicated in the activity of inverse agonists but not agonists.
|
J Biol Chem
|
2002
|
0.90
|
|
47
|
PACAP type I receptor transactivation is essential for IGF-1 receptor signalling and antiapoptotic activity in neurons.
|
EMBO J
|
2007
|
0.90
|
|
48
|
β-Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice.
|
Diabetologia
|
2013
|
0.89
|
|
49
|
Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation.
|
J Neurosci
|
2013
|
0.89
|
|
50
|
Divergent evolution in metabotropic glutamate receptors. A new receptor activated by an endogenous ligand different from glutamate in insects.
|
J Biol Chem
|
2003
|
0.89
|
|
51
|
Characterization and localization of cocaine- and amphetamine-regulated transcript (CART) binding sites.
|
Peptides
|
2005
|
0.89
|
|
52
|
Difference in mass analysis using labeled lysines (DIMAL-K): a new, efficient proteomic quantification method applied to the analysis of astrocytic secretomes.
|
Mol Cell Proteomics
|
2005
|
0.89
|
|
53
|
5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling.
|
Mol Biol Cell
|
2007
|
0.89
|
|
54
|
A proteomic approach based on peptide affinity chromatography, 2-dimensional electrophoresis and mass spectrometry to identify multiprotein complexes interacting with membrane-bound receptors.
|
Biol Proced Online
|
2002
|
0.89
|
|
55
|
beta-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic beta-cells.
|
J Biol Chem
|
2008
|
0.88
|
|
56
|
Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists.
|
Biol Psychiatry
|
2005
|
0.88
|
|
57
|
Constitutive activity of serotonin 2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants.
|
Mol Pharmacol
|
2010
|
0.88
|
|
58
|
5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10.
|
ACS Chem Neurosci
|
2012
|
0.86
|
|
59
|
Molecular and functional characterization of proteins interacting with the C-terminal domains of 5-HT2 receptors: emergence of 5-HT2 "receptosomes".
|
Biol Cell
|
2004
|
0.85
|
|
60
|
Caffeic acid phenethyl ester (CAPE) prevents inflammatory stress in organotypic hippocampal slice cultures.
|
Brain Res Mol Brain Res
|
2003
|
0.85
|
|
61
|
Quantitative assessment of transcriptome differences between brain territories.
|
Genome Res
|
2003
|
0.83
|
|
62
|
Widespread brain distribution of the Drosophila metabotropic glutamate receptor.
|
Neuroreport
|
2008
|
0.82
|
|
63
|
Transcription of the mouse PAC1 receptor gene: cell-specific expression and regulation by Zac1.
|
Biochim Biophys Acta
|
2002
|
0.82
|
|
64
|
Proteomic detection of prostate-specific antigen using a serum fractionation procedure: potential implication for new low-abundance cancer biomarkers detection.
|
Anal Biochem
|
2005
|
0.82
|
|
65
|
Dynamic reorganization of the astrocyte actin cytoskeleton elicited by cAMP and PACAP: a role for phosphatidylInositol 3-kinase inhibition.
|
Eur J Neurosci
|
2005
|
0.82
|
|
66
|
3,4-N-methlenedioxymethamphetamine-induced hypophagia is maintained in 5-HT1B receptor knockout mice, but suppressed by the 5-HT2C receptor antagonist RS102221.
|
Neuropsychopharmacology
|
2005
|
0.81
|
|
67
|
S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization.
|
J Pharmacol Exp Ther
|
2011
|
0.81
|
|
68
|
Effects of oral monosodium (L)-glutamate on insulin secretion and glucose tolerance in healthy volunteers.
|
Br J Clin Pharmacol
|
2002
|
0.81
|
|
69
|
Constitutive secretion of protease nexin-1 by glial cells and its regulation by G-protein-coupled receptors.
|
J Neurosci
|
2005
|
0.80
|
|
70
|
Quantitative phosphoproteomics unravels biased phosphorylation of serotonin 2A receptor at Ser280 by hallucinogenic versus nonhallucinogenic agonists.
|
Mol Cell Proteomics
|
2014
|
0.79
|
|
71
|
Calcineurin interacts with the serotonin transporter C-terminus to modulate its plasma membrane expression and serotonin uptake.
|
J Neurosci
|
2013
|
0.79
|
|
72
|
The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors.
|
Int J Neuropsychopharmacol
|
2010
|
0.79
|
|
73
|
Implication of p53 and caspase-3 in kainic acid but not in N-methyl-D-aspartic acid-induced apoptosis in organotypic hippocampal mouse cultures.
|
Neurosci Lett
|
2002
|
0.79
|
|
74
|
Inhibition of voltage-gated Ca2+ channels by antazoline.
|
Neuroreport
|
2002
|
0.79
|
|
75
|
Effect of Glutamate and Ionomycin on the Release of Arachidonic Acid, Prostaglandins and HETEs from Cultured Neurons and Astrocytes.
|
Eur J Neurosci
|
1991
|
0.79
|
|
76
|
[Feeding disorders in 5-HT4 receptor knockout mice].
|
J Soc Biol
|
2004
|
0.79
|
|
77
|
Gαo is required for L-canavanine detection in Drosophila.
|
PLoS One
|
2013
|
0.78
|
|
78
|
Up-regulation of the PACAP type-1 receptor (PAC1) promoter by neurotrophins in rat PC12 cells and mouse cerebellar granule cells via the Ras/mitogen-activated protein kinase cascade.
|
J Neurochem
|
2002
|
0.78
|
|
79
|
The Identification and Localization of the Guanine Nucleotide Binding Protein G0 in the Auditory System.
|
Eur J Neurosci
|
1991
|
0.78
|
|
80
|
Hyperfunction of muscarinic receptor maintains long-term memory in 5-HT4 receptor knock-out mice.
|
PLoS One
|
2010
|
0.78
|
|
81
|
Immature-like astrocytes are associated with dentate granule cell migration in human temporal lobe epilepsy.
|
Neurosci Lett
|
2002
|
0.77
|
|
82
|
Quantitative proteomic analysis reveals protein expression changes in the murine neuronal secretome during apoptosis.
|
J Proteomics
|
2012
|
0.77
|
|
83
|
Enhancement of reference memory in aged rats by specific activation of 5-HT(4) receptors using an olfactory associative discrimination task.
|
Brain Res
|
2011
|
0.76
|
|
84
|
Pharmacological profile of engineered 5-HT₄ receptors and identification of 5-HT₄ receptor-biased ligands.
|
Brain Res
|
2012
|
0.75
|
|
85
|
[When two molecules involved in the regulation of mood meet: mutual modulation of the serotonin transporter and neuronal NO-synthase].
|
Med Sci (Paris)
|
2007
|
0.75
|
|
86
|
[The mTOR pathway: a new target for treating cognitive deficits of schizophrenia?].
|
Med Sci (Paris)
|
2013
|
0.75
|
|
87
|
Techniques for studying inverse agonist activity of antidepressants at recombinant nonedited 5-HT(₂C-INI) receptor and native neuronal 5-HT(₂C) receptors.
|
Methods Enzymol
|
2010
|
0.75
|