Published in J Biol Chem on February 11, 2005
Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence. PLoS Biol (2015) 2.01
Host cell manipulation by the human pathogen Toxoplasma gondii. Cell Mol Life Sci (2008) 1.49
Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med (2009) 1.42
Modulation of the host cell proteome by the intracellular apicomplexan parasite Toxoplasma gondii. Infect Immun (2007) 1.18
Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis. Proc Natl Acad Sci U S A (2009) 1.12
Apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in apicomplexan parasite Toxoplasma gondii. J Biol Chem (2011) 1.09
Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids. Biochemistry (2007) 1.00
Toxoplasma gondii Hsp20 is a stripe-arranged chaperone-like protein associated with the outer leaflet of the inner membrane complex. Biol Cell (2008) 0.98
Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans. Prog Lipid Res (2013) 0.96
Library of Apicomplexan Metabolic Pathways: a manually curated database for metabolic pathways of apicomplexan parasites. Nucleic Acids Res (2012) 0.94
Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis. PLoS Comput Biol (2015) 0.94
A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs. FASEB J (2010) 0.91
Interaction between parasitophorous vacuolar membrane-associated GRA3 and calcium modulating ligand of host cell endoplasmic reticulum in the parasitism of Toxoplasma gondii. Korean J Parasitol (2008) 0.91
Novel roles for ATP-binding cassette G transporters in lipid redistribution in Toxoplasma. Mol Microbiol (2010) 0.87
Phosphatidylethanolamine synthesis in the parasite mitochondrion is required for efficient growth but dispensable for survival of Toxoplasma gondii. J Biol Chem (2014) 0.86
Deficiency of a Niemann-Pick, type C1-related protein in toxoplasma is associated with multiple lipidoses and increased pathogenicity. PLoS Pathog (2011) 0.85
Toxoplasma gondii-skeletal muscle cells interaction increases lipid droplet biogenesis and positively modulates the production of IL-12, IFN-g and PGE2. Parasit Vectors (2014) 0.83
Eimeria falciformis infection of the mouse caecum identifies opposing roles of IFNγ-regulated host pathways for the parasite development. Mucosal Immunol (2013) 0.81
The obligate intracellular parasite Toxoplasma gondii secretes a soluble phosphatidylserine decarboxylase. J Biol Chem (2012) 0.80
The intracellular parasite Toxoplasma gondii depends on the synthesis of long-chain and very long-chain unsaturated fatty acids not supplied by the host cell. Mol Microbiol (2015) 0.79
Conditional mutagenesis of a novel choline kinase demonstrates plasticity of phosphatidylcholine biogenesis and gene expression in Toxoplasma gondii. J Biol Chem (2012) 0.78
Starvation of low-density lipoprotein-derived cholesterol induces bradyzoite conversion in Toxoplasma gondii. Parasit Vectors (2014) 0.77
Metabolic Cooperation of Glucose and Glutamine Is Essential for the Lytic Cycle of Obligate Intracellular Parasite Toxoplasma gondii. J Biol Chem (2015) 0.76
Epidemiology and clinico-investigative study of organisms causing vaginal discharge. Indian J Sex Transm Dis (2017) 0.75
Tracing amino acid exchange during host-pathogen interaction by combined stable-isotope time-resolved Raman spectral imaging. Sci Rep (2016) 0.75
Optogenetic monitoring identifies phosphatidylthreonine-regulated calcium homeostasis in Toxoplasma gondii. Microb Cell (2016) 0.75
Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphate Acyltransferase. PLoS Pathog (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Membrane lipids: where they are and how they behave. Nat Rev Mol Cell Biol (2008) 13.77
By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. Cell (2003) 3.65
Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages. J Exp Med (2006) 3.52
Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space. Cell (2006) 2.79
Making heads or tails of phospholipids in mitochondria. J Cell Biol (2011) 2.55
The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization. Biochem J (2007) 2.27
Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells. Science (2008) 2.15
Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites. J Cell Sci (2003) 1.85
Sites of interaction between aldolase and thrombospondin-related anonymous protein in plasmodium. Mol Biol Cell (2003) 1.83
Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infect Immun (2007) 1.79
Golgi biogenesis in Toxoplasma gondii. Nature (2002) 1.67
Characterization of a novel organelle in Toxoplasma gondii with similar composition and function to the plant vacuole. Mol Microbiol (2010) 1.61
Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Mol Microbiol (2008) 1.56
Activation of NF-kappaB by Toxoplasma gondii correlates with increased expression of antiapoptotic genes and localization of phosphorylated IkappaB to the parasitophorous vacuole membrane. J Cell Sci (2003) 1.52
The host cell transcription factor hypoxia-inducible factor 1 is required for Toxoplasma gondii growth and survival at physiological oxygen levels. Cell Microbiol (2006) 1.50
A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complex. Mol Biol Cell (2006) 1.49
Apicomplexan gliding motility and host cell invasion: overhauling the motor model. Trends Parasitol (2004) 1.47
Four distinct pathways of hemoglobin uptake in the malaria parasite Plasmodium falciparum. Proc Natl Acad Sci U S A (2008) 1.47
Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med (2009) 1.42
Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae. J Biol Chem (2007) 1.39
Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem (2007) 1.39
A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites. Mol Biochem Parasitol (2004) 1.38
Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii. Mol Microbiol (2010) 1.36
Translation regulation by eukaryotic initiation factor-2 kinases in the development of latent cysts in Toxoplasma gondii. J Biol Chem (2008) 1.34
Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils. J Biol Chem (2008) 1.33
Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection. Proc Natl Acad Sci U S A (2009) 1.33
In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway. J Biol Chem (2005) 1.31
Uptake and utilization of lyso-phosphatidylethanolamine by Saccharomyces cerevisiae. J Biol Chem (2006) 1.29
Autophagy in protists. Autophagy (2011) 1.29
The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission. PLoS Pathog (2009) 1.28
TLR2 signaling is critical for Mycoplasma pneumoniae-induced airway mucin expression. J Immunol (2005) 1.26
Cellular interactions of Plasmodium liver stage with its host mammalian cell. Int J Parasitol (2007) 1.25
The cathepsin B of Toxoplasma gondii, toxopain-1, is critical for parasite invasion and rhoptry protein processing. J Biol Chem (2002) 1.24
Pulmonary surfactant protein A up-regulates activity of the mannose receptor, a pattern recognition receptor expressed on human macrophages. J Immunol (2002) 1.23
Phosphatidylserine transport to the mitochondria is regulated by ubiquitination. J Biol Chem (2002) 1.23
Pulmonary collectins enhance phagocytosis of Mycobacterium avium through increased activity of mannose receptor. J Immunol (2004) 1.21
Surfactant protein A inhibits peptidoglycan-induced tumor necrosis factor-alpha secretion in U937 cells and alveolar macrophages by direct interaction with toll-like receptor 2. J Biol Chem (2001) 1.21
Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models. J Infect Dis (2011) 1.21
Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic (2012) 1.21
Anionic pulmonary surfactant phospholipids inhibit inflammatory responses from alveolar macrophages and U937 cells by binding the lipopolysaccharide-interacting proteins CD14 and MD-2. J Biol Chem (2009) 1.20
Cell cycle-regulated vesicular trafficking of Toxoplasma APT1, a protein localized to multiple apicoplast membranes. Mol Microbiol (2007) 1.20
A surface phospholipase is involved in the migration of plasmodium sporozoites through cells. J Biol Chem (2004) 1.19
Autophagy in parasitic protists: unique features and drug targets. Mol Biochem Parasitol (2011) 1.19
Host but not parasite cholesterol controls Toxoplasma cell entry by modulating organelle discharge. Mol Biol Cell (2003) 1.18
Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut. Proc Natl Acad Sci U S A (2011) 1.13
AP-1 in Toxoplasma gondii mediates biogenesis of the rhoptry secretory organelle from a post-Golgi compartment. J Biol Chem (2002) 1.12
Pseudomonas aeruginosa twitching motility-mediated chemotaxis towards phospholipids and fatty acids: specificity and metabolic requirements. J Bacteriol (2008) 1.12
On the biogenesis of lipid bodies in ancient eukaryotes: synthesis of triacylglycerols by a Toxoplasma DGAT1-related enzyme. Mol Biochem Parasitol (2004) 1.10
A thioredoxin family protein of the apicoplast periphery identifies abundant candidate transport vesicles in Toxoplasma gondii. Eukaryot Cell (2008) 1.10
Surfactant protein D inhibition of human macrophage uptake of Mycobacterium tuberculosis is independent of bacterial agglutination. J Immunol (2002) 1.10
Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes. J Infect Dis (2011) 1.10
A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii. Biol Cell (2008) 1.09
FXYD proteins stabilize Na,K-ATPase: amplification of specific phosphatidylserine-protein interactions. J Biol Chem (2011) 1.08
Host cell lipids control cholesteryl ester synthesis and storage in intracellular Toxoplasma. Cell Microbiol (2005) 1.08
A Toxoplasma palmitoyl acyl transferase and the palmitoylated armadillo repeat protein TgARO govern apical rhoptry tethering and reveal a critical role for the rhoptries in host cell invasion but not egress. PLoS Pathog (2013) 1.08
Toxoplasma gondii Rab5 enhances cholesterol acquisition from host cells. Cell Microbiol (2002) 1.08
Are rhoptries in Apicomplexan parasites secretory granules or secretory lysosomal granules? Mol Microbiol (2004) 1.08
Pulmonary surfactant protein D inhibits lipopolysaccharide (LPS)-induced inflammatory cell responses by altering LPS binding to its receptors. J Biol Chem (2008) 1.07
Plasmodium salvages cholesterol internalized by LDL and synthesized de novo in the liver. Cell Microbiol (2010) 1.07
Metamorphosis of the malaria parasite in the liver is associated with organelle clearance. Cell Res (2010) 1.06
Altered lung surfactant system in a Rab38-deficient rat model of Hermansky-Pudlak syndrome. Am J Physiol Lung Cell Mol Physiol (2009) 1.06
Protective properties and surface localization of Plasmodium falciparum enolase. Infect Immun (2007) 1.04
Plasmodium falciparum enolase: stage-specific expression and sub-cellular localization. Malar J (2009) 1.04
A family of aspartic proteases and a novel, dynamic and cell-cycle-dependent protease localization in the secretory pathway of Toxoplasma gondii. Traffic (2007) 1.04
Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum. Antimicrob Agents Chemother (2008) 1.04
A high-affinity putrescine-cadaverine transporter from Trypanosoma cruzi. Mol Microbiol (2010) 1.04
Actin is required for endocytic trafficking in the malaria parasite Plasmodium falciparum. Cell Microbiol (2007) 1.02
Toxopain-1 is critical for infection in a novel chicken embryo model of congenital toxoplasmosis. Infect Immun (2004) 1.02
Biochemical and genetic analysis of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum. J Biol Chem (2008) 1.02
Surfactant protein D increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages. Infect Immun (2006) 1.01
Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2. J Biol Chem (2010) 1.01
Phosphatidylglycerol suppresses influenza A virus infection. Am J Respir Cell Mol Biol (2011) 1.01
The Plasmodium falciparum Vps4 homolog mediates multivesicular body formation. J Cell Sci (2004) 1.00
Surfactant protein D regulates airway function and allergic inflammation through modulation of macrophage function. Am J Respir Crit Care Med (2003) 1.00
Distinct roles of Plasmodium rhomboid 1 in parasite development and malaria pathogenesis. PLoS Pathog (2009) 0.99
Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages. J Biol Chem (2011) 0.99
Surfactant protein A is defective in abrogating inflammation in asthma. Am J Physiol Lung Cell Mol Physiol (2011) 0.98
Circulating oxidized LDL forms complexes with beta2-glycoprotein I: implication as an atherogenic autoantigen. J Lipid Res (2003) 0.98
Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay. BMC Biochem (2010) 0.98
Identification of gene encoding Plasmodium knowlesi phosphatidylserine decarboxylase by genetic complementation in yeast and characterization of in vitro maturation of encoded enzyme. J Biol Chem (2011) 0.98
A membrane protease is targeted to the relict plastid of toxoplasma via an internal signal sequence. Traffic (2007) 0.97
Serum surfactant protein D is increased in acute and chronic inflammation in mice. Cytokine (2005) 0.97
Surfactant protein A binds Mycoplasma pneumoniae with high affinity and attenuates its growth by recognition of disaturated phosphatidylglycerols. J Biol Chem (2004) 0.97
Traffic to the malaria parasite food vacuole: a novel pathway involving a phosphatidylinositol 3-phosphate-binding protein. J Biol Chem (2007) 0.96
Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito. J Biol Chem (2010) 0.96
A mutation in Rab38 small GTPase causes abnormal lung surfactant homeostasis and aberrant alveolar structure in mice. Am J Pathol (2008) 0.96
Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Mol Biol Cell (2009) 0.96
Characterisation of Toxoplasma gondii engineered to express mouse interferon-gamma. Int J Parasitol (2003) 0.96
Pleiotropic effect due to targeted depletion of secretory rhoptry protein ROP2 in Toxoplasma gondii. J Cell Sci (2003) 0.95
Neutral lipid synthesis and storage in the intraerythrocytic stages of Plasmodium falciparum. Mol Biochem Parasitol (2004) 0.95
Peculiarities of host cholesterol transport to the unique intracellular vacuole containing Toxoplasma. Traffic (2005) 0.95