How C-type lectins detect pathogens.

Mycobacterium tuberculosis: success through dormancy. FEMS Microbiol Rev (2012) 2.07

Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor. J Leukoc Biol (2006) 1.80

On the hunt for helminths: innate immune cells in the recognition and response to helminth parasites. Cell Microbiol (2008) 1.50

The lectin receptor kinase-VI.2 is required for priming and positively regulates Arabidopsis pattern-triggered immunity. Plant Cell (2012) 1.32

DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis. PLoS Med (2005) 1.30

Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. Blood (2005) 1.22

Stimulation of anti-tumor immunity by photodynamic therapy. Expert Rev Clin Immunol (2011) 1.11

A helminth immunomodulator exploits host signaling events to regulate cytokine production in macrophages. PLoS Pathog (2011) 1.10

Human dendritic cell subsets for vaccination. J Clin Immunol (2005) 1.09

Nipah virus uses leukocytes for efficient dissemination within a host. J Virol (2011) 1.05

Hepatitis C virus association with peripheral blood B lymphocytes potentiates viral infection of liver-derived hepatoma cells. Blood (2008) 1.05

Targeting of DC-SIGN on human dendritic cells by minor fimbriated Porphyromonas gingivalis strains elicits a distinct effector T cell response. J Immunol (2009) 1.05

Directing dendritic cell immunotherapy towards successful cancer treatment. Immunotherapy (2010) 1.04

Macrophages in tuberculosis: friend or foe. Semin Immunopathol (2013) 1.04

A C-type lectin MGL1/CD301a plays an anti-inflammatory role in murine experimental colitis. Am J Pathol (2008) 1.03

Decreased expression of intelectin 1 in the human airway epithelium of smokers compared to nonsmokers. J Immunol (2008) 1.01

The Rosetteless gene controls development in the choanoflagellate S. rosetta. Elife (2014) 1.01

DC-SIGN and influenza hemagglutinin dynamics in plasma membrane microdomains are markedly different. Biophys J (2011) 1.00

Role for alpha-L-fucosidase in the control of Helicobacter pylori-infected gastric cancer cells. Proc Natl Acad Sci U S A (2009) 0.97

Effect of differential N-linked and O-linked mannosylation on recognition of fungal antigens by dendritic cells. PLoS One (2007) 0.97

A look behind closed doors: interaction of persistent viruses with dendritic cells. Nat Rev Microbiol (2010) 0.96

Utilization of DC-SIGN for entry of feline coronaviruses into host cells. J Virol (2008) 0.96

C-type lectin in Chlamys farreri (CfLec-1) mediating immune recognition and opsonization. PLoS One (2011) 0.94

C1q- and collectin-dependent phagocytosis of apoptotic host cells by the intestinal protozoan Entamoeba histolytica. J Infect Dis (2008) 0.93

Lectin domains at the frontiers of plant defense. Front Plant Sci (2014) 0.93

Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection. PLoS One (2013) 0.92

Recognition of bacterial surface polysaccharides by lectins of the innate immune system and its contribution to defense against infection: the case of pulmonary pathogens. Infect Immun (2007) 0.92

Recognition of the major cat allergen Fel d 1 through the cysteine-rich domain of the mannose receptor determines its allergenicity. J Biol Chem (2011) 0.92

Lectin receptor kinases in plant innate immunity. Front Plant Sci (2013) 0.91

Differential expression profiling of components associated with exoskeletal hardening in crustaceans. BMC Genomics (2008) 0.91

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite. J Biol Chem (2011) 0.90

Super-resolution imaging of C-type lectin and influenza hemagglutinin nanodomains on plasma membranes using blink microscopy. Biophys J (2012) 0.88

Macrophage immunoregulatory pathways in tuberculosis. Semin Immunol (2014) 0.88

Conceptual bases for prey biorecognition and feeding selectivity in the microplanktonic marine phagotroph Oxyrrhis marina. Microb Ecol (2008) 0.87

The macrophage galactose-type lectin can function as an attachment and entry receptor for influenza virus. J Virol (2013) 0.86

Transcriptome analysis of duck liver and identification of differentially expressed transcripts in response to duck hepatitis A virus genotype C infection. PLoS One (2013) 0.86

Sensing of Mycobacterium tuberculosis and consequences to both host and bacillus. Immunol Rev (2015) 0.86

Adaptive evolution of a novel Drosophila lectin induced by parasitic wasp attack. Mol Biol Evol (2011) 0.86

Dendritic cell populations in colon and mesenteric lymph nodes of patients with Crohn's disease. J Histochem Cytochem (2007) 0.85

Super-resolution imaging of C-type lectin spatial rearrangement within the dendritic cell plasma membrane at fungal microbe contact sites. Front Phys (2014) 0.85

Profiles of carbohydrate ligands associated with adsorbed proteins on self-assembled monolayers of defined chemistries. J Biomed Mater Res A (2010) 0.84

Deficient serum mannose-binding lectin levels and MBL2 polymorphisms increase the risk of single and recurrent Cryptosporidium infections in young children. J Infect Dis (2009) 0.84

Structural features, evolutionary relationships, and transcriptional regulation of C-type lectin-domain proteins in Manduca sexta. Insect Biochem Mol Biol (2014) 0.84

Temperature-induced viral resistance in Emiliania huxleyi (Prymnesiophyceae). PLoS One (2014) 0.83

The formation and stability of DC-SIGN microdomains require its extracellular moiety. Traffic (2012) 0.82

Moult cycle specific differential gene expression profiling of the crab Portunus pelagicus. BMC Genomics (2011) 0.82

Evolutionary genetics as a tool to target genes involved in phenotypes of medical relevance. Evol Appl (2009) 0.82

The modular nature of dendritic cell responses to commensal and pathogenic fungi. PLoS One (2012) 0.82

A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN. Chem Commun (Camb) (2010) 0.81

Pattern Recognition Receptors in HIV Transmission. Front Immunol (2012) 0.80

N-glycans of human protein C inhibitor: tissue-specific expression and function. PLoS One (2011) 0.80

Utilization of human DC-SIGN and L-SIGN for entry and infection of host cells by the New World arenavirus, Junín virus. Biochem Biophys Res Commun (2013) 0.80

Hydroxyproline O-arabinosyltransferase mutants oppositely alter tip growth in Arabidopsis thaliana and Physcomitrella patens. Plant J (2015) 0.79

Human tandem-repeat-type galectins bind bacterial non-βGal polysaccharides. Glycoconj J (2013) 0.79

Dendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle? Virology (Auckl) (2013) 0.79

A negative effect of Campylobacter capsule on bacterial interaction with an analogue of a host cell receptor. BMC Microbiol (2014) 0.78

Molecular Characterization and Global Expression Analysis of Lectin Receptor Kinases in Bread Wheat (Triticum aestivum). PLoS One (2016) 0.78

Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN. Sci Rep (2016) 0.78

CfLec-3 from scallop: an entrance to non-self recognition mechanism of invertebrate C-type lectin. Sci Rep (2015) 0.78

Proteomic View of Interactions of Shiga Toxin-Producing Escherichia coli with the Intestinal Environment in Gnotobiotic Piglets. PLoS One (2013) 0.77

Lack of association between CLEC5A gene single-nucleotide polymorphisms and Kawasaki disease in Taiwanese children. J Biomed Biotechnol (2011) 0.77

Notable Aspects of Glycan-Protein Interactions. Biomolecules (2015) 0.77

Dectin-1-CD37 association regulates IL-6 expression during Toxoplasma gondii infection. Parasitol Res (2014) 0.76

Evidence for a novel Entamoeba histolytica lectin activity that recognises carbohydrates present on ovalbumin. Int J Parasitol (2010) 0.76

Nitrogen-deficient microalgae are rich in cell-surface mannose: potential implications for prey biorecognition by phagotrophic protozoa. Braz J Microbiol (2009) 0.76

The scavenger receptor repertoire in six cnidarian species and its putative role in cnidarian-dinoflagellate symbiosis. PeerJ (2016) 0.75

Animal lectins: potential receptors for ginseng polysaccharides. J Ginseng Res (2015) 0.75

Pathogen recognition of a novel C-type lectin from Marsupenaeus japonicus reveals the divergent sugar-binding specificity of QAP motif. Sci Rep (2017) 0.75

Engineering the Pseudomonas aeruginosa II lectin: designing mutants with changed affinity and specificity. J Comput Aided Mol Des (2014) 0.75

AV119, a natural sugar from avocado gratissima, modulates the LPS-induced proinflammatory response in human keratinocytes. Inflammation (2011) 0.75

Human herpesvirus 8 infects and replicates in Langerhans cells and interstitial dermal dendritic cells and impairs their function. J Virol (2017) 0.75

Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity. Sci Rep (2017) 0.75

Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol (2005) 5.80

Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J Cell Biol (2013) 3.77

The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J Immunol (2002) 3.48

Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol (2007) 3.42

Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev (2003) 2.52

Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res (2003) 2.32

The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells. Eur J Immunol (2003) 2.30

TRPM7, a novel regulator of actomyosin contractility and cell adhesion. EMBO J (2006) 2.20

Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination. Cancer Res (2012) 2.08

In situ tumor ablation creates an antigen source for the generation of antitumor immunity. Cancer Res (2004) 2.06

Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice. J Clin Invest (2011) 1.91

Myosin II and mechanotransduction: a balancing act. Trends Cell Biol (2007) 1.85

Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity. Blood (2011) 1.83

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production. Blood (2008) 1.79

Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1. J Biol Chem (2002) 1.71

Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy. Cancer Immunol Immunother (2010) 1.60

Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma. Am J Respir Crit Care Med (2010) 1.60

Hotspots of GPI-anchored proteins and integrin nanoclusters function as nucleation sites for cell adhesion. Proc Natl Acad Sci U S A (2009) 1.60

Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood (2005) 1.57

Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clin Cancer Res (2003) 1.57

Dual function of C-type lectin-like receptors in the immune system. Curr Opin Cell Biol (2003) 1.53

Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. J Biol Chem (2008) 1.50

(19)F MRI for quantitative in vivo cell tracking. Trends Biotechnol (2010) 1.49

Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome. J Clin Oncol (2005) 1.48

Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells. J Cell Biol (2004) 1.48

Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients. Clin Cancer Res (2010) 1.45

Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines. Int J Cancer (2007) 1.42

Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes. J Immunol (2003) 1.41

The heme-heme oxygenase system: a molecular switch in wound healing. Blood (2003) 1.39

The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion. J Biol Chem (2002) 1.39

A critical role for prostaglandin E2 in podosome dissolution and induction of high-speed migration during dendritic cell maturation. J Immunol (2006) 1.37

Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients. Cancer Res (2013) 1.35

Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy? Lancet Oncol (2012) 1.34

The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells. Blood (2012) 1.34

TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol (2008) 1.32

Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. J Control Release (2010) 1.32

Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood (2005) 1.30

Elevated CXCL16 expression by synovial macrophages recruits memory T cells into rheumatoid joints. Arthritis Rheum (2005) 1.29

Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clin Cancer Res (2011) 1.29

Synergy between in situ cryoablation and TLR9 stimulation results in a highly effective in vivo dendritic cell vaccine. Cancer Res (2006) 1.26

Organization of the integrin LFA-1 in nanoclusters regulates its activity. Mol Biol Cell (2006) 1.26

Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol Oncol (2010) 1.24

Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin Cancer Res (2009) 1.24

Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities. Blood (2012) 1.23

DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production. J Leukoc Biol (2008) 1.22

Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets. Blood (2012) 1.21

Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging. Proc Natl Acad Sci U S A (2011) 1.19

Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. PLoS One (2008) 1.19

PGE2-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA-Rho-kinase axis. J Cell Sci (2008) 1.18

Customizable, multi-functional fluorocarbon nanoparticles for quantitative in vivo imaging using 19F MRI and optical imaging. Biomaterials (2010) 1.18

Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration. Cancer Immunol Immunother (2008) 1.15

Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesion. Proc Natl Acad Sci U S A (2012) 1.15

Functional differences between mesenchymal stem cell populations are reflected by their transcriptome. Stem Cells Dev (2010) 1.14

Phenotypical and functional characterization of clinical grade dendritic cells. J Immunother (2002) 1.12

Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients. Clin Cancer Res (2012) 1.11

Migration of dendritic cell based cancer vaccines: in vivo veritas? Curr Opin Immunol (2005) 1.11

Maximizing dendritic cell migration in cancer immunotherapy. Expert Opin Biol Ther (2008) 1.11

Nanoscale organization of the pathogen receptor DC-SIGN mapped by single-molecule high-resolution fluorescence microscopy. Chemphyschem (2007) 1.10

Ligand-conjugated quantum dots monitor antigen uptake and processing by dendritic cells. Nano Lett (2007) 1.10

Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion. J Immunol (2013) 1.09

The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum. J Leukoc Biol (2004) 1.09

Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production. J Immunol (2007) 1.08

Interlaboratory round robin on cantilever calibration for AFM force spectroscopy. Ultramicroscopy (2011) 1.08

The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC. FEBS Lett (2008) 1.07

Commonly used prophylactic vaccines as an alternative for synthetically produced TLR ligands to mature monocyte-derived dendritic cells. Blood (2010) 1.07

Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice. PLoS One (2009) 1.07

Targeted antigen delivery and activation of dendritic cells in vivo: steps towards cost effective vaccines. Semin Immunol (2011) 1.06

Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation. Blood (2011) 1.06

The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity. PLoS Pathog (2009) 1.05

Targeting dendritic cells--why bother? Blood (2013) 1.04

Expression of the dendritic cell-associated C-type lectin DC-SIGN by inflammatory matrix metalloproteinase-producing macrophages in rheumatoid arthritis synovium and interaction with intercellular adhesion molecule 3-positive T cells. Arthritis Rheum (2003) 1.04

Wild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide used. Cancer Immunol Immunother (2010) 1.04

Labeling cells for in vivo tracking using (19)F MRI. Biomaterials (2012) 1.04

Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after Fc gamma RII-mediated uptake. J Exp Med (2006) 1.03

Skin-test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma. Cancer Res (2012) 1.03

Cytokine analysis as a tool to understand tumour-host interaction in ovarian cancer. Eur J Cancer (2011) 1.03

Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells. Cancer Res (2011) 1.03

Targeting antigens to dendritic cells in vivo. Immunobiology (2006) 1.02

In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients. Cancer Res (2009) 1.02

Human plasmacytoid dendritic cells phagocytose, process, and present exogenous particulate antigen. J Immunol (2010) 1.02

A novel (19)F agent for detection and quantification of human dendritic cells using magnetic resonance imaging. Int J Cancer (2010) 1.01

Human plasmacytoid dendritic cells: from molecules to intercellular communication network. Front Immunol (2013) 0.99

Analysis of dendritic cell trafficking using EGFP-transgenic mice. Immunol Lett (2003) 0.98

The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival. Sci Signal (2012) 0.97

Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells. Clin Cancer Res (2013) 0.96

Dendritic cells: tools and targets for antitumor vaccination. Expert Rev Vaccines (2005) 0.96

The C-type lectin DC-SIGN internalizes soluble antigens and HIV-1 virions via a clathrin-dependent mechanism. Eur J Immunol (2009) 0.96

In vivo colocalization of antigen and CpG [corrected] within dendritic cells is associated with the efficacy of cancer immunotherapy. Cancer Res (2008) 0.96

Immunogenicity of dendritic cells pulsed with CEA peptide or transfected with CEA mRNA for vaccination of colorectal cancer patients. Anticancer Res (2010) 0.96

Harnessing human plasmacytoid dendritic cells as professional APCs. Cancer Immunol Immunother (2012) 0.94

The influence of PEG chain length and targeting moiety on antibody-mediated delivery of nanoparticle vaccines to human dendritic cells. Biomaterials (2011) 0.94

DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells. Eur J Immunol (2011) 0.94

Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR. Int J Cancer (2007) 0.93

Dendritic cell-based nanovaccines for cancer immunotherapy. Curr Opin Immunol (2013) 0.93

Monocyte cell surface glycosaminoglycans positively modulate IL-4-induced differentiation toward dendritic cells. J Immunol (2008) 0.93

The stem cell markers Oct4A, Nanog and c-Myc are expressed in ascites cells and tumor tissue of ovarian cancer patients. Cell Oncol (Dordr) (2013) 0.92

Multimodal imaging of nanovaccine carriers targeted to human dendritic cells. Mol Pharm (2011) 0.91

Levels of complexity in pathogen recognition by C-type lectins. Curr Opin Immunol (2005) 0.91