Published in EMBO J on January 12, 2006
Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow. Biophys J (2006) 3.83
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol Rev (2010) 2.66
Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation. J Biol Chem (2009) 2.47
The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase. Cell (2014) 2.22
Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions. J Cell Sci (2009) 2.13
Molecular determinants of Mg2+ and Ca2+ permeability and pH sensitivity in TRPM6 and TRPM7. J Biol Chem (2007) 1.75
Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells. Mol Biol Cell (2007) 1.64
Cells move when ions and water flow. Pflugers Arch (2006) 1.52
Protons make tumor cells move like clockwork. Pflugers Arch (2009) 1.48
Cellular magnesium homeostasis. Arch Biochem Biophys (2011) 1.46
Rapid and Localized Mechanical Stimulation and Adhesion Assay: TRPM7 Involvement in Calcium Signaling and Cell Adhesion. PLoS One (2015) 1.41
TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol (2008) 1.32
Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells. Cell Stem Cell (2013) 1.30
Self-organized podosomes are dynamic mechanosensors. Curr Biol (2008) 1.29
Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. PLoS One (2008) 1.19
Remodeling of calcium signaling in tumor progression. J Biomed Sci (2013) 1.19
TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane. Proc Natl Acad Sci U S A (2008) 1.17
Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent. Oncogene (2013) 1.16
Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway. Cardiovasc Res (2009) 1.16
The alpha-kinase family: an exceptional branch on the protein kinase tree. Cell Mol Life Sci (2009) 1.16
TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions. Curr Pharm Biotechnol (2011) 1.14
Regulation of cancer invasiveness by the physical extracellular matrix environment. Cell Adh Migr (2009) 1.09
Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes. PLoS One (2010) 1.08
TRPM7 activates m-calpain by stress-dependent stimulation of p38 MAPK and c-Jun N-terminal kinase. J Mol Biol (2010) 1.07
Tissue kallikrein stimulates Ca(2+) reabsorption via PKC-dependent plasma membrane accumulation of TRPV5. EMBO J (2006) 1.05
Crystal structure of the alpha-kinase domain of Dictyostelium myosin heavy chain kinase A. Sci Signal (2010) 1.04
Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma. Cancer Lett (2010) 1.04
Supervillin couples myosin-dependent contractility to podosomes and enables their turnover. J Cell Sci (2012) 1.03
Cross-talk between calcium and protein kinase A in the regulation of cell migration. Curr Opin Cell Biol (2011) 1.03
Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase. PLoS One (2010) 1.01
Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7. Br J Pharmacol (2012) 1.01
TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD? Biochim Biophys Acta (2007) 1.00
TRPM7 regulates polarized cell movements. Biochem J (2011) 1.00
Autophosphorylation activates Dictyostelium myosin II heavy chain kinase A by providing a ligand for an allosteric binding site in the alpha-kinase domain. J Biol Chem (2010) 0.99
TRPM7 regulates gastrulation during vertebrate embryogenesis. Dev Biol (2010) 0.98
trpm7 regulation of in vivo cation homeostasis and kidney function involves stanniocalcin 1 and fgf23. Endocrinology (2010) 0.96
Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke? Prog Neurobiol (2014) 0.96
Regulation of the epithelial Mg2+ channel TRPM6 by estrogen and the associated repressor protein of estrogen receptor activity (REA). J Biol Chem (2009) 0.96
TRPM7 is required within zebrafish sensory neurons for the activation of touch-evoked escape behaviors. J Neurosci (2011) 0.95
Regulation of podosome formation, microglial migration and invasion by Ca(2+)-signaling molecules expressed in podosomes. J Neuroinflammation (2012) 0.94
TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways. Cell Signal (2014) 0.94
The immunological synapse: a dynamic platform for local signaling. J Clin Immunol (2010) 0.94
The heavy chain has its day: regulation of myosin-II assembly. Bioarchitecture (2014) 0.94
Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma. Cancer Lett (2011) 0.93
TRPM7 channel is sensitive to osmotic gradients in human kidney cells. J Physiol (2007) 0.93
Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C γ2 (PLCγ2) using TRPM7-kinase. Cell Signal (2012) 0.92
The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k. Cell Signal (2010) 0.92
Comparative kinetic and functional characterization of the motor domains of human nonmuscle myosin-2C isoforms. J Biol Chem (2011) 0.92
Proton conductivity through the human TRPM7 channel and its molecular determinants. J Biol Chem (2008) 0.91
Cellular traction stresses mediate extracellular matrix degradation by invadopodia. Acta Biomater (2014) 0.90
Importance of RhoGTPases in formation, characteristics, and functions of invadosomes. Small GTPases (2014) 0.90
Suppression of TRPM7 inhibits proliferation, migration, and invasion of malignant human glioma cells. CNS Neurosci Ther (2014) 0.89
Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer. Cells (2014) 0.89
TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells. Cell Calcium (2013) 0.88
Podosomes in space: macrophage migration and matrix degradation in 2D and 3D settings. Cell Adh Migr (2014) 0.88
Emerging role of TRP channels in cell migration: from tumor vascularization to metastasis. Front Physiol (2013) 0.87
Activation of TRPM7 channels by small molecules under physiological conditions. Pflugers Arch (2014) 0.87
TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets. Scientifica (Cairo) (2012) 0.85
TRPM7 Regulates Axonal Outgrowth and Maturation of Primary Hippocampal Neurons. Mol Neurobiol (2014) 0.85
Distinct mechanisms regulating mechanical force-induced Ca²⁺ signals at the plasma membrane and the ER in human MSCs. Elife (2015) 0.84
Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice. Sci Rep (2014) 0.84
TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions. Cell Mol Life Sci (2014) 0.83
TRPM7 regulates vascular endothelial cell adhesion and tube formation. Am J Physiol Cell Physiol (2014) 0.83
TRPM7 in cerebral ischemia and potential target for drug development in stroke. Acta Pharmacol Sin (2011) 0.83
hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+ entry and calpain 2. J Cell Biol (2013) 0.83
Mechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through Osterix pathway. Sci Rep (2015) 0.82
Integrin α1β1 participates in chondrocyte transduction of osmotic stress. Biochem Biophys Res Commun (2014) 0.82
Prolonged mechanical stretch initiates intracellular calcium oscillations in human mesenchymal stem cells. PLoS One (2014) 0.82
Buxus Microphylla var. Koreana Nakai Extract for the Treatment of Gastric Cancer. J Pharmacopuncture (2013) 0.81
Magnesium and embryonic development. Magnes Res (2014) 0.81
Post-Translational Modifications of TRP Channels. Cells (2014) 0.81
Expression and contributions of TRPM7 and KCa2.3/SK3 channels to the increased migration and invasion of microglia in anti-inflammatory activation states. PLoS One (2014) 0.81
TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migration. Br J Pharmacol (2014) 0.80
Natural and Synthetic Modulators of the TRPM7 Channel. Cells (2014) 0.80
TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation. Oncotarget (2015) 0.80
Current understanding of TRPM7 pharmacology and drug development for stroke. Acta Pharmacol Sin (2012) 0.79
Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) α-kinase domain apoenzyme reveals a novel autoinhibited conformation. Sci Rep (2016) 0.79
Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget (2016) 0.78
Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture. Nat Commun (2016) 0.78
A double TRPtych: six views of transient receptor potential channels in disease and health. J Neurosci (2008) 0.78
TRPM7 is a molecular substrate of ATP-evoked P2X7-like currents in tumor cells. J Gen Physiol (2016) 0.78
Phosphorylation of tropomodulin1 contributes to the regulation of actin filament architecture in cardiac muscle. FASEB J (2014) 0.78
The plasma membrane potential and the organization of the actin cytoskeleton of epithelial cells. Int J Cell Biol (2012) 0.78
The Transient Receptor Potential Melastatin 7 Channel Regulates Pancreatic Cancer Cell Invasion through the Hsp90α/uPA/MMP2 pathway. Neoplasia (2017) 0.77
Spatiotemporal organization and mechanosensory function of podosomes. Cell Adh Migr (2014) 0.77
Characterization of the Catalytic and Nucleotide Binding Properties of the α-Kinase Domain of Dictyostelium Myosin-II Heavy Chain Kinase A. J Biol Chem (2015) 0.77
TRPM7, the cytoskeleton and neuronal death. Channels (Austin) (2012) 0.77
Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Sci Rep (2015) 0.76
TRPM7 kinase activity regulates murine mast cell degranulation. J Physiol (2016) 0.76
Trpm7 Protein Contributes to Intercellular Junction Formation in Mouse Urothelium. J Biol Chem (2015) 0.75
F-actin dampens NLRP3 inflammasome activity via Flightless-I and LRRFIP2. Sci Rep (2016) 0.75
TRPM7 and its role in neurodegenerative diseases. Channels (Austin) (2015) 0.75
Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion. Elife (2017) 0.75
Role of transient receptor potential melastatin type 7 channel in gastric cancer. Integr Med Res (2016) 0.75
The TRPM7 channel kinase regulates store-operated calcium entry. J Physiol (2017) 0.75
MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines. FEBS Open Bio (2014) 0.75
Mibefradil represents a new class of benzimidazole TRPM7 channel agonists. Pflugers Arch (2015) 0.75
Redox-sensitive transient receptor potential channels in oxygen sensing and adaptation. Pflugers Arch (2015) 0.75
Conventional myosins - unconventional functions. Biophys Rev (2010) 0.75
Constitutive calcium entry and cancer: updated views and insights. Eur Biophys J (2017) 0.75
Rho and Rac take center stage. Cell (2004) 10.64
LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature (2001) 5.52
Podosomes: adhesion hot-spots of invasive cells. Trends Cell Biol (2003) 4.51
TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science (2001) 4.33
Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. Cell (2003) 4.15
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol (1994) 3.65
The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol (2002) 3.63
The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. J Cell Biol (1997) 3.28
Exploring the neighborhood: adhesion-coupled cell mechanosensors. Cell (2002) 3.15
Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol (2003) 3.11
Gelsolin, a multifunctional actin regulatory protein. J Biol Chem (1999) 2.64
Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo. Cell (1993) 2.61
Src protein-tyrosine kinase structure and regulation. Biochem Biophys Res Commun (2004) 2.23
Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale. Mol Biol Cell (2002) 1.93
Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading. Nat Cell Biol (1999) 1.87
Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation. Biochemistry (2005) 1.73
Phosphorylation of annexin I by TRPM7 channel-kinase. J Biol Chem (2004) 1.63
Elongation factor-2 kinase and its newly discovered relatives. FEBS Lett (2002) 1.52
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. J Biol Chem (2003) 1.47
Alpha-kinases: analysis of the family and comparison with conventional protein kinases. Prog Biophys Mol Biol (2004) 1.46
MIC channels are inhibited by internal divalent cations but not ATP. Biophys J (2003) 1.35
Calcium and polyphosphoinositide control of cytoskeletal dynamics. Trends Neurosci (1989) 1.32
Signaling pathways regulating Dictyostelium myosin II. J Muscle Res Cell Motil (2002) 1.22
Differential localization in cells of myosin II heavy chain kinases during cytokinesis and polarized migration. BMC Cell Biol (2002) 1.21
Actin cytoskeleton remodelling via local inhibition of contractility at discrete microdomains. J Cell Sci (2004) 1.20
Critical regions for assembly of vertebrate nonmuscle myosin II. Biochemistry (2005) 1.20
Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly. Blood (2004) 1.20
Dictyostelium myosin heavy chain kinase A regulates myosin localization during growth and development. J Cell Biol (1996) 1.10
Dictyostelium myosin bipolar thick filament formation: importance of charge and specific domains of the myosin rod. PLoS Biol (2004) 1.07
Alpha-kinase 1, a new component in apical protein transport. J Biol Chem (2005) 1.02
Cytoskeletal reorganization internalizes multiple transient receptor potential channels and blocks calcium entry into human neutrophils. J Immunol (2004) 1.01
The role of myosin heavy chain phosphorylation in Dictyostelium motility, chemotaxis and F-actin localization. J Cell Sci (2004) 0.97
Myosin heavy chain kinase B participates in the regulation of myosin assembly into the cytoskeleton. J Cell Biochem (2003) 0.92
c-Abl regulation: a tail of two lipids. Curr Biol (2003) 0.90
Localization of calcium entry through calcium channels in olfactory receptor neurones using a laser scanning microscope and the calcium indicator dyes Fluo-3 and Fura-Red. Cell Calcium (1994) 0.88
Nutrient stimulation results in a rapid Ca2+-dependent threonine phosphorylation of myosin heavy chain in rat pancreatic islets and RINm5F cells. J Biol Chem (1998) 0.82
The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer (2003) 6.70
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol (2005) 5.80
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron (2008) 3.97
Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J Cell Biol (2013) 3.77
The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J Immunol (2002) 3.48
Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol (2007) 3.42
A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity. Cell (2005) 3.35
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol (2006) 3.24
Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator. EMBO Rep (2004) 2.98
Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission. Biophys J (2004) 2.55
Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev (2003) 2.52
Bright cyan fluorescent protein variants identified by fluorescence lifetime screening. Nat Methods (2010) 2.43
Regulation and biological activities of the autotaxin-LPA axis. Prog Lipid Res (2007) 2.39
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell (2010) 2.37
Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res (2003) 2.32
The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells. Eur J Immunol (2003) 2.30
A comparison of donor-acceptor pairs for genetically encoded FRET sensors: application to the Epac cAMP sensor as an example. PLoS One (2008) 2.23
Autophagy regulates ageing in C. elegans. Autophagy (2007) 2.22
Lysophosphatidic acid is a potential mediator of cholestatic pruritus. Gastroenterology (2010) 2.18
International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature. Pharmacol Rev (2010) 2.10
Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination. Cancer Res (2012) 2.08
Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. Cancer Cell (2004) 2.08
In situ tumor ablation creates an antigen source for the generation of antitumor immunity. Cancer Res (2004) 2.06
Integrins control motile strategy through a Rho-cofilin pathway. J Cell Biol (2005) 2.04
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate. J Biol Chem (2005) 1.95
Calcium signaling regulates translocation and activation of Rac. J Biol Chem (2003) 1.94
Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale. Mol Biol Cell (2002) 1.93
Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice. J Clin Invest (2011) 1.91
Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity (2003) 1.89
Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia. Cell (2007) 1.89
Myosin II and mechanotransduction: a balancing act. Trends Cell Biol (2007) 1.85
Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity. Blood (2011) 1.83
Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81
Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proc Natl Acad Sci U S A (2010) 1.80
Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production. Blood (2008) 1.79
Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. J Biol Chem (2009) 1.78
How C-type lectins detect pathogens. Cell Microbiol (2005) 1.77
Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1. J Biol Chem (2002) 1.71
Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry. Anal Chem (2006) 1.71
Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape. Immunity (2005) 1.64
Phosphorylation of annexin I by TRPM7 channel-kinase. J Biol Chem (2004) 1.63
Autotaxin and LPA receptor signaling in cancer. Cancer Metastasis Rev (2011) 1.61
Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy. Cancer Immunol Immunother (2010) 1.60
TRPM7 is essential for Mg(2+) homeostasis in mammals. Nat Commun (2010) 1.60
Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma. Am J Respir Crit Care Med (2010) 1.60
Hotspots of GPI-anchored proteins and integrin nanoclusters function as nucleation sites for cell adhesion. Proc Natl Acad Sci U S A (2009) 1.60
Construction of human activity-based phosphorylation networks. Mol Syst Biol (2013) 1.59
PIP2 signaling in lipid domains: a critical re-evaluation. EMBO J (2005) 1.59
Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1. J Biol Chem (2002) 1.57
Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood (2005) 1.57
Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clin Cancer Res (2003) 1.57
Dual function of C-type lectin-like receptors in the immune system. Curr Opin Cell Biol (2003) 1.53
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet (2013) 1.52
Plasma lysophosphatidic acid concentration and ovarian cancer. JAMA (2002) 1.51
Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. J Biol Chem (2008) 1.50
The channel kinases TRPM6 and TRPM7 are functionally nonredundant. J Biol Chem (2005) 1.50
(19)F MRI for quantitative in vivo cell tracking. Trends Biotechnol (2010) 1.49
A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range. PLoS One (2011) 1.49
Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome. J Clin Oncol (2005) 1.48
Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells. J Cell Biol (2004) 1.48
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. J Biol Chem (2003) 1.47
Alpha-kinases: analysis of the family and comparison with conventional protein kinases. Prog Biophys Mol Biol (2004) 1.46
Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients. Clin Cancer Res (2010) 1.45
Acute suppression of spontaneous neurotransmission drives synaptic potentiation. J Neurosci (2013) 1.43
Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines. Int J Cancer (2007) 1.42
Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes. J Immunol (2003) 1.41
Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin. J Med Chem (2005) 1.40
The heme-heme oxygenase system: a molecular switch in wound healing. Blood (2003) 1.39
The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion. J Biol Chem (2002) 1.39
A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders. Proc Natl Acad Sci U S A (2005) 1.37
A critical role for prostaglandin E2 in podosome dissolution and induction of high-speed migration during dendritic cell maturation. J Immunol (2006) 1.37
Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients. Cancer Res (2013) 1.35
Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity. Org Lett (2006) 1.34
Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy? Lancet Oncol (2012) 1.34
The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells. Blood (2012) 1.34
Spider and bacterial sphingomyelinases D target cellular lysophosphatidic acid receptors by hydrolyzing lysophosphatidylcholine. J Biol Chem (2004) 1.33
8-pCPT-2'-O-Me-cAMP-AM: an improved Epac-selective cAMP analogue. Chembiochem (2008) 1.32
TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol (2008) 1.32
Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. J Control Release (2010) 1.32
Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood (2005) 1.30
Elevated CXCL16 expression by synovial macrophages recruits memory T cells into rheumatoid joints. Arthritis Rheum (2005) 1.29
Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clin Cancer Res (2011) 1.29
TRPM7 is required for breast tumor cell metastasis. Cancer Res (2012) 1.27
Synergy between in situ cryoablation and TLR9 stimulation results in a highly effective in vivo dendritic cell vaccine. Cancer Res (2006) 1.26
Organization of the integrin LFA-1 in nanoclusters regulates its activity. Mol Biol Cell (2006) 1.26
Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate. J Cell Biol (2007) 1.25
Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol Oncol (2010) 1.24