Published in BMC Genomics on March 10, 2005
Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies. Am J Hum Genet (2006) 3.67
A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53
Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias. BMC Genomics (2012) 1.39
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms. Am J Hum Genet (2007) 1.24
Genome-wide association studies: quality control and population-based measures. Genet Epidemiol (2009) 1.14
Improvements to bead-based oligonucleotide ligation SNP genotyping assays. Biotechniques (2008) 1.04
Large-scale profiling of microRNAs for The Cancer Genome Atlas. Nucleic Acids Res (2015) 0.83
Pooled genome-wide analysis to identify novel risk loci for pediatric allergic asthma. PLoS One (2011) 0.83
mESAdb: microRNA expression and sequence analysis database. Nucleic Acids Res (2011) 0.83
ALG: automated genotype calling of Luminex assays. PLoS One (2011) 0.80
Identifying molecular subtypes in human colon cancer using gene expression and DNA methylation microarray data. Int J Oncol (2015) 0.79
Convergence among non-sister dendritic branches: an activity-controlled mean to strengthen network connectivity. PLoS One (2008) 0.77
Analysis of copy number variation using quantitative interspecies competitive PCR. Nucleic Acids Res (2008) 0.76
Statistical comparison framework and visualization scheme for ranking-based algorithms in high-throughput genome-wide studies. J Comput Biol (2009) 0.75
Comprehensive Identification of Sexual Dimorphism-Associated Differentially Expressed Genes in Two-Way Factorial Designed RNA-Seq Data on Japanese Quail (Coturnix coturnix japonica). PLoS One (2015) 0.75
Visible Genotype Sensor Array. Sensors (Basel) (2008) 0.75
TAMGeS: a Three-array Method for Genotyping of SNPs by a dual-colour approach. BMC Genomics (2007) 0.75
Accessing genetic variation: genotyping single nucleotide polymorphisms. Nat Rev Genet (2001) 5.00
Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res (1999) 4.59
A system for specific, high-throughput genotyping by allele-specific primer extension on microarrays. Genome Res (2000) 2.94
Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays. Genome Res (2000) 2.79
Algorithms for large-scale genotyping microarrays. Bioinformatics (2003) 2.66
SNPstream UHT: ultra-high throughput SNP genotyping for pharmacogenomics and drug discovery. Biotechniques (2002) 2.25
Arrayed primer extension: solid-phase four-color DNA resequencing and mutation detection technology. Genet Test (2000) 2.01
Quantitative evaluation by minisequencing and microarrays reveals accurate multiplexed SNP genotyping of whole genome amplified DNA. Nucleic Acids Res (2003) 1.99
Multiplex SNP genotyping in pooled DNA samples by a four-colour microarray system. Nucleic Acids Res (2002) 1.44
Rapid detection of mitochondrial sequence polymorphisms using multiplex solid-phase fluorescent minisequencing. Genomics (1996) 1.12
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med (2008) 9.61
Transcriptome and genome sequencing uncovers functional variation in humans. Nature (2013) 8.89
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet (2009) 5.75
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet (2005) 4.80
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A (2007) 4.71
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Investigation of the fine structure of European populations with applications to disease association studies. Eur J Hum Genet (2008) 3.65
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
High-resolution, high-throughput SNP mapping in Drosophila melanogaster. Nat Methods (2008) 2.55
Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories. Nat Biotechnol (2013) 2.53
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes (2010) 2.44
Multiplex padlock targeted sequencing reveals human hypermutable CpG variations. Genome Res (2009) 2.38
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes (2011) 2.21
An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. Hum Mol Genet (2007) 2.14
Sex chromosome evolution and speciation in Ficedula flycatchers. Proc Biol Sci (2003) 2.08
Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation. Genome Res (2008) 2.03
Quantitative evaluation by minisequencing and microarrays reveals accurate multiplexed SNP genotyping of whole genome amplified DNA. Nucleic Acids Res (2003) 1.99
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5. Hum Mol Genet (2008) 1.98
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus. Hum Mol Genet (2007) 1.95
Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease. Circ Cardiovasc Genet (2010) 1.86
Multiple displacement amplification to create a long-lasting source of DNA for genetic studies. Hum Mutat (2006) 1.86
Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development. PLoS Genet (2011) 1.82
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis. Arthritis Rheum (2007) 1.72
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med (2013) 1.70
Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia--a comparative study of four differently designed, high resolution microarray platforms. Genes Chromosomes Cancer (2008) 1.66
Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus. PLoS Genet (2011) 1.59
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia. Genome Biol (2013) 1.57
Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients. Genes Chromosomes Cancer (2008) 1.54
A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response. Pharmacogenetics (2003) 1.52
The mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing. Hum Mutat (2015) 1.46
Single nucleotide polymorphisms predict the change in left ventricular mass in response to antihypertensive treatment. J Hypertens (2004) 1.45
Multiplex SNP genotyping in pooled DNA samples by a four-colour microarray system. Nucleic Acids Res (2002) 1.44
DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia. Blood (2009) 1.42
[Pharmacogenetics--pathway to individualized antihypertensive pharmacotherapy]. Lakartidningen (2003) 1.39
Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene. Diabetes (2005) 1.38
Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control study. Breast Cancer Res (2004) 1.36
Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells. Nucleic Acids Res (2007) 1.36
Genetic analysis of an F(2) intercross between two chicken lines divergently selected for body-weight. BMC Genomics (2009) 1.27
Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus. Arthritis Rheum (2010) 1.27
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood (2012) 1.26
Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery. PLoS One (2011) 1.21
Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity. Obesity (Silver Spring) (2007) 1.18
Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. Diabetes (2011) 1.13
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations. Eur J Hum Genet (2012) 1.09
Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease. Hum Mol Genet (2003) 1.05
Evaluation of HapMap data in six populations of European descent. Eur J Hum Genet (2008) 1.04
Genetic variation in putative regulatory loci controlling gene expression in breast cancer. Proc Natl Acad Sci U S A (2006) 1.03
Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men. Dement Geriatr Cogn Disord (2009) 1.02
A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE. Eur J Hum Genet (2010) 1.01
Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers. Pharmacogenomics J (2009) 1.00
Coffee consumption and CYP1A2 genotype in relation to bone mineral density of the proximal femur in elderly men and women: a cohort study. Nutr Metab (Lond) (2010) 0.99
Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression. PLoS One (2012) 0.98
The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population. BMC Med Genet (2008) 0.97
Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study. BMC Cancer (2008) 0.97
DNA methylation analysis of bone marrow cells at diagnosis of acute lymphoblastic leukemia and at remission. PLoS One (2012) 0.97
Next-generation sequencing technologies and applications for human genetic history and forensics. Investig Genet (2011) 0.97
A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol. Twin Res Hum Genet (2012) 0.95
Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men. J Clin Endocrinol Metab (2008) 0.95
Commemorating two centuries of iodine research: an interdisciplinary overview of current research. Angew Chem Int Ed Engl (2011) 0.95
Microarrays for genotyping human group a rotavirus by multiplex capture and type-specific primer extension. J Clin Microbiol (2003) 0.93
Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. Circ Cardiovasc Genet (2012) 0.92
Genetic variations in the tissue factor gene are associated with clinical outcome in acute coronary syndrome and expression levels in human monocytes. Arterioscler Thromb Vasc Biol (2005) 0.92
Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment. BMC Genomics (2013) 0.92
A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus. Ann Rheum Dis (2009) 0.90
Association between genetic variants in the tumour necrosis factor/lymphotoxin α/lymphotoxin β locus and primary Sjogren's syndrome in Scandinavian samples. Ann Rheum Dis (2012) 0.90
A quality assessment survey of SNP genotyping laboratories. Hum Mutat (2006) 0.89
Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4. Ann Rheum Dis (2012) 0.87
The transcriptome of the adenovirus infected cell. Virology (2012) 0.87
Common and low-frequency genetic variants in the PCSK9 locus influence circulating PCSK9 levels. Arterioscler Thromb Vasc Biol (2012) 0.86
Analysis of genetic variation in the GenomEUtwin project. Twin Res (2003) 0.85
Association of genes in the NF-κB pathway with antibody-positive primary Sjögren's syndrome. Scand J Immunol (2013) 0.85
Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants. Circ Cardiovasc Genet (2013) 0.84
Genotyping single-nucleotide polymorphisms by minisequencing using tag arrays. Methods Mol Med (2005) 0.84
Niemann-Pick C1 modulates hepatic triglyceride metabolism and its genetic variation contributes to serum triglyceride levels. Arterioscler Thromb Vasc Biol (2010) 0.84
Single nucleotide polymorphisms in the apolipoprotein B and low density lipoprotein receptor genes affect response to antihypertensive treatment. BMC Cardiovasc Disord (2004) 0.84
SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling. Int J Radiat Oncol Biol Phys (2013) 0.84
Enhanced hydrogen formation during the catalytic decomposition of H2O2 on metal oxide surfaces in the presence of HO radical scavengers. Phys Chem Chem Phys (2013) 0.84
Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds. Pharmacogenet Genomics (2006) 0.83
Evidence of association between interferon regulatory factor 5 gene polymorphisms and asthma. Gene (2012) 0.83
Detecting imbalanced expression of SNP alleles by minisequencing on microarrays. BMC Biotechnol (2004) 0.82
Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap. PLoS One (2010) 0.82
Kinetics and mechanisms of reactions between H2O2 and copper and copper oxides. Dalton Trans (2015) 0.82
NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO). Circ Cardiovasc Genet (2015) 0.82
Association of the estrogen receptor 1 (ESR1) gene with body height in adult males from two Swedish population cohorts. PLoS One (2008) 0.81
Dried reagents for multiplex genotyping by tag-array minisequencing to be used in microfluidic devices. Analyst (2010) 0.81
Salt-inducible kinase 1 influences Na(+),K(+)-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure. J Hypertens (2011) 0.81