Published in Curr Diab Rep on April 01, 2005
Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein. Protein Sci (2007) 0.99
High glucose induces human endothelial dysfunction through an Axl-dependent mechanism. Cardiovasc Diabetol (2014) 0.98
Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration. Diabetologia (2009) 0.96
Green Tea Attenuates Oxidative Stress and Downregulates the Expression of Angiotensin II AT(1) Receptor in Renal and Hepatic Tissues of Streptozotocin-Induced Diabetic Rats. Evid Based Complement Alternat Med (2012) 0.80
Formation of methionine sulfoxide during glycoxidation and lipoxidation of ribonuclease A. Arch Biochem Biophys (2006) 0.77
Hypolipidemic Activity of Chloroform Extract of Mimosa pudica Leaves. Avicenna J Med Biotechnol (2010) 0.76
Antidiabetic effects of Mangifera indica Kernel Flour-supplemented diet in streptozotocin-induced type 2 diabetes in rats. Food Sci Nutr (2016) 0.75
Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metab (2008) 7.97
Retinopathy in diabetes. Diabetes Care (2004) 4.25
Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA (2002) 4.18
Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes (2010) 2.94
Activation of protein kinase C isoforms and its impact on diabetic complications. Circ Res (2010) 2.87
Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes. Nat Clin Pract Endocrinol Metab (2007) 2.48
Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein. J Biol Chem (2004) 2.35
Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat Med (2009) 2.31
The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest (2003) 2.11
Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metab (2010) 2.09
The role of protein kinase C activation and the vascular complications of diabetes. Pharmacol Res (2007) 2.06
Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study. Diabetes Care (2011) 2.00
Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes. Diabetes (2007) 1.99
Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue. Circulation (2002) 1.84
Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance. Diabetes (2006) 1.71
Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications. Proc Natl Acad Sci U S A (2008) 1.70
Diabetic retinopathy. Diabetes Care (2003) 1.61
Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development. Dev Dyn (2003) 1.58
Diabetic retinopathy. Diabetes Care (2003) 1.52
Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor. Cancer Biol Ther (2009) 1.52
Vascular complications of diabetes: mechanisms of injury and protective factors. Cell Metab (2013) 1.51
Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study. Diabetes Care (2007) 1.46
Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. J Clin Invest (2003) 1.43
A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKε. Cell Res (2011) 1.40
Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes. Diabetes (2002) 1.39
Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice. Diabetes (2006) 1.31
miR-K12-7-5p encoded by Kaposi's sarcoma-associated herpesvirus stabilizes the latent state by targeting viral ORF50/RTA. PLoS One (2011) 1.29
Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance. Arterioscler Thromb Vasc Biol (2005) 1.29
Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation. Diabetes (2003) 1.21
Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arterioscler Thromb Vasc Biol (2006) 1.21
Pathophysiologic differences among Asians, native Hawaiians, and other Pacific Islanders and treatment implications. Diabetes Care (2012) 1.21
Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization. Proc Natl Acad Sci U S A (2002) 1.19
Oxidative stress and antioxidant treatment in diabetes. Ann N Y Acad Sci (2004) 1.19
Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity. Kidney Int (2011) 1.18
Protective effects of GLP-1 on glomerular endothelium and its inhibition by PKCβ activation in diabetes. Diabetes (2012) 1.18
Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation. J Biol Chem (2005) 1.17
Differential regulation of angiotensin II-induced expression of connective tissue growth factor by protein kinase C isoforms in the myocardium. J Biol Chem (2005) 1.16
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans. J Clin Invest (2011) 1.15
Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain. FASEB J (2006) 1.14
Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes. Diabetes (2003) 1.12
Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis. J Biol Chem (2003) 1.09
Differential regulation of VEGF signaling by PKC-alpha and PKC-epsilon in endothelial cells. Arterioscler Thromb Vasc Biol (2008) 1.09
Selective regulation of heme oxygenase-1 expression and function by insulin through IRS1/phosphoinositide 3-kinase/Akt-2 pathway. J Biol Chem (2008) 1.05
The effect of vitamin E on endothelial function of micro- and macrocirculation and left ventricular function in type 1 and type 2 diabetic patients. Diabetes (2005) 1.05
Microvascular complications of diabetes. Endocrinol Metab Clin North Am (2004) 1.03
Identification of linguistic barriers to diabetes knowledge and glycemic control in Chinese Americans with diabetes. Diabetes Care (2006) 1.02
Induction of vascular insulin resistance and endothelin-1 expression and acceleration of atherosclerosis by the overexpression of protein kinase C-β isoform in the endothelium. Circ Res (2013) 1.02
Diacylglycerol production and protein kinase C activity are increased in a mouse model of diabetic embryopathy. Diabetes (2002) 1.00
Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells. J Neurosci (2005) 1.00
Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells. J Biol Chem (2001) 0.98
Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats. Diabetes (2007) 0.98
New perspectives on diabetic vascular complications: the loss of endogenous protective factors induced by hyperglycemia. Diabetes Metab J (2011) 0.98
Oxidative stress: the lead or supporting actor in the pathogenesis of diabetic complications. J Am Soc Nephrol (2003) 0.96
Molecular targets of diabetic cardiovascular complications. Curr Drug Targets (2005) 0.96
Murine gammaherpesvirus 68 evades host cytokine production via replication transactivator-induced RelA degradation. J Virol (2011) 0.95
Regulation of progranulin expression in myeloid cells. Am J Physiol Regul Integr Comp Physiol (2006) 0.94
Inhibition of insulin signaling in endothelial cells by protein kinase C-induced phosphorylation of p85 subunit of phosphatidylinositol 3-kinase (PI3K). J Biol Chem (2011) 0.93
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells. Mol Cell Biol (2013) 0.92
Modulating Notch signaling to enhance neovascularization and reperfusion in diabetic mice. Biomaterials (2010) 0.88
Glomerular VEGF resistance induced by PKCδ/SHP-1 activation and contribution to diabetic nephropathy. FASEB J (2012) 0.87
Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice. Arterioscler Thromb Vasc Biol (2012) 0.86
Kidney complications: factors that protect the diabetic vasculature. Nat Med (2010) 0.86
Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function. Am J Physiol Heart Circ Physiol (2009) 0.86
Protein kinase Cbeta isoform inhibitors: a new treatment for diabetic cardiovascular diseases. Circulation (2004) 0.85
Retinal not systemic oxidative and inflammatory stress correlated with VEGF expression in rodent models of insulin resistance and diabetes. Invest Ophthalmol Vis Sci (2012) 0.85
Transforming growth factor beta-1 and incidence of heart failure in older adults: the Cardiovascular Health Study. Cytokine (2012) 0.84
Vascular endothelial growth factor-induced neovascularization rescues cardiac function but not adverse remodeling at advanced ischemic heart disease. Arterioscler Thromb Vasc Biol (2012) 0.84
Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans. Free Radic Biol Med (2012) 0.84
Carboxyl-terminal amino acids 1052 to 1082 of the latency-associated nuclear antigen (LANA) interact with RBP-Jκ and are responsible for LANA-mediated RTA repression. J Virol (2012) 0.83
A cross-sectional characterization of insulin resistance by phenotype and insulin clamp in East Asian Americans with type 1 and type 2 diabetes. PLoS One (2011) 0.83
Differential expression of human telomerase catalytic subunit mRNA by in situ hybridization in pheochromocytomas. Endocr Pathol (2006) 0.82
Clinical safety of the selective PKC-beta inhibitor, ruboxistaurin. Expert Opin Drug Saf (2006) 0.82
Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes. Diabetes Care (2004) 0.81
PKCδ inhibition normalizes the wound-healing capacity of diabetic human fibroblasts. J Clin Invest (2016) 0.81
Synthesis of dihydrobenzo[b]furans by diastereoselective acyloxyarylation. Chem Commun (Camb) (2014) 0.80
More sugar, less blood vessels: another piece in the puzzle of increased cardiovascular risk in diabetes. Arterioscler Thromb Vasc Biol (2008) 0.80
Implications of treatment that target protective mechanisms against diabetic nephropathy. Semin Nephrol (2012) 0.79
Summary statement IV: Obesity and diabetes: opportunities for translation of basic research. Vascul Pharmacol (2006) 0.79
Latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus promotes angiogenesis through targeting notch signaling effector Hey1. Cancer Res (2014) 0.79
Bactericidal/permeability-increasing protein's signaling pathways and its retinal trophic and anti-angiogenic effects. FASEB J (2006) 0.79
SGLT5 reabsorbs fructose in the kidney but its deficiency paradoxically exacerbates hepatic steatosis induced by fructose. PLoS One (2013) 0.79
Endothelium-dependent delivery of insulin to muscle interstitium. Cell Metab (2011) 0.78
A complex interplay of factors causes diabetic nephropathy. Metabolism (2010) 0.78
Sexual dysfunction as a marker of cardiovascular disease in males with 50 or more years of type 1 diabetes. Diabetes Care (2013) 0.77
Glypican 4, a membrane binding protein for bactericidal/permeability-increasing protein signaling pathways in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2007) 0.77
Can protein kinase C beta-selective inhibitor, ruboxistaurin, stop vascular complications in diabetic patients? Diabetes Care (2005) 0.77
An efficient and general iron-catalyzed C-C bond activation with 1,3-dicarbonyl units as a leaving groups. Angew Chem Int Ed Engl (2011) 0.77
Diabetes: Podocytes lose their footing. Nature (2010) 0.76
Differential effects of bactericidal/permeability-increasing protein (BPI) analogues on retinal neovascularization and retinal pericyte growth. Invest Ophthalmol Vis Sci (2002) 0.76
Insulin regulates SOCS2 expression and the mitogenic effect of IGF-1 in mesangial cells. Kidney Int (2008) 0.75