Published in Shock on April 01, 2005
Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury. J Biol Chem (2005) 1.66
A spatial model of tumor-host interaction: application of chemotherapy. Math Biosci Eng (2009) 1.10
Mitochondria and energetic depression in cell pathophysiology. Int J Mol Sci (2009) 0.95
Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice. Free Radic Biol Med (2010) 0.82
Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes. Am J Physiol Heart Circ Physiol (2010) 0.79
Heat shock protein 22 (Hsp22) regulates oxidative phosphorylation upon its mitochondrial translocation with the inducible nitric oxide synthase in mammalian heart. PLoS One (2015) 0.79
The valosin-containing protein is a novel mediator of mitochondrial respiration and cell survival in the heart in vivo. Sci Rep (2017) 0.75
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science (2005) 6.69
Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science (2003) 6.66
Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha. Science (2003) 3.91
The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1. Nat Cell Biol (2009) 3.40
Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway. Nat Cell Biol (2003) 2.96
The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance. J Bioenerg Biomembr (2008) 2.50
Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals. Proc Natl Acad Sci U S A (2004) 2.44
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. Circulation (2005) 2.35
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. Proc Natl Acad Sci U S A (2007) 2.34
Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia. J Mol Cell Cardiol (2003) 2.34
Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways. Biochem J (2003) 2.27
TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents. J Clin Invest (2006) 2.04
Nitric oxide and mitochondrial signaling: from physiology to pathophysiology. Arterioscler Thromb Vasc Biol (2007) 1.82
Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death. J Immunol (2011) 1.81
Phagocytosis executes delayed neuronal death after focal brain ischemia. Proc Natl Acad Sci U S A (2013) 1.78
Hypoxia accelerates nitric oxide-dependent inhibition of mitochondrial complex I in activated macrophages. Am J Physiol Regul Integr Comp Physiol (2004) 1.74
Y-27632, a Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells. J Urol (2003) 1.74
Mitochondria as signaling organelles in the vascular endothelium. Proc Natl Acad Sci U S A (2006) 1.72
Glycolysis: a bioenergetic or a survival pathway? Trends Biochem Sci (2009) 1.71
Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome? Circ Res (2007) 1.62
E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation. Proc Natl Acad Sci U S A (2009) 1.62
Regulation of oxygen distribution in tissues by endothelial nitric oxide. Circ Res (2009) 1.61
AMPKalpha1 regulates the antioxidant status of vascular endothelial cells. Biochem J (2009) 1.55
Retracted Mitochondrial dynamics, biogenesis, and function are coordinated with the cell cycle by APC/C CDH1. Cell Metab (2012) 1.54
The deleterious effect of high concentrations of D-glucose requires pro-inflammatory preconditioning. J Hypertens (2008) 1.52
Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes. Proc Natl Acad Sci U S A (2010) 1.50
Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression. J Biol Chem (2003) 1.49
Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats. Diabetes (2003) 1.43
Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response. Nat Cell Biol (2004) 1.38
Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase. Proc Natl Acad Sci U S A (2004) 1.34
Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase. J Immunol (2006) 1.33
Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes. Glia (2002) 1.29
Inhibition of cellular respiration by endogenously produced carbon monoxide. J Cell Sci (2006) 1.29
Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. Proc Natl Acad Sci U S A (2004) 1.26
Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state. J Biol Chem (2007) 1.25
S-nitrosation of mitochondrial complex I depends on its structural conformation. J Biol Chem (2007) 1.21
Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration. Front Pharmacol (2012) 1.20
BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro. J Urol (2003) 1.20
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle. Proc Natl Acad Sci U S A (2011) 1.18
Neuronal death induced by nanomolar amyloid β is mediated by primary phagocytosis of neurons by microglia. J Biol Chem (2011) 1.17
MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation. J Neurosci (2012) 1.17
Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation. Cancer Res (2006) 1.17
Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis. Eur Heart J (2005) 1.16
Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells. Proc Natl Acad Sci U S A (2011) 1.15
Nitric oxide, cytochrome C oxidase, and the cellular response to hypoxia. Arterioscler Thromb Vasc Biol (2009) 1.15
Lack of oxygen deactivates mitochondrial complex I: implications for ischemic injury? J Biol Chem (2009) 1.10
S-nitrosothiol inhibition of mitochondrial complex I causes a reversible increase in mitochondrial hydrogen peroxide production. Biochim Biophys Acta (2006) 1.10
Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration. J Neuroinflammation (2005) 1.09
Mitochondrial biogenesis as a cellular signaling framework. Biochem Pharmacol (2004) 1.09
Inhibition of mitochondrial respiration by endogenous nitric oxide: a critical step in Fas signaling. Proc Natl Acad Sci U S A (2002) 1.07
Nitric oxide: orchestrating hypoxia regulation through mitochondrial respiration and the endoplasmic reticulum stress response. Cell Res (2005) 1.07
Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study. J Neuroinflammation (2006) 1.06
Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation. J Neurochem (2005) 1.06
Discrepancies between nitroglycerin and NO-releasing drugs on mitochondrial oxygen consumption, vasoactivity, and the release of NO. Circ Res (2005) 1.05
Cytochrome c oxidase regulates endogenous nitric oxide availability in respiring cells: a possible explanation for hypoxic vasodilation. Proc Natl Acad Sci U S A (2007) 1.04
Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion. Free Radic Biol Med (2003) 1.02
Nitric oxide stimulates PC12 cell proliferation via cGMP and inhibits at higher concentrations mainly via energy depletion. Nitric Oxide (2005) 1.02
Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling. J Neuroinflammation (2012) 1.02
Mitochondria in apoptosis of ischemic heart. FEBS Lett (2003) 1.01
Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production. J Neurochem (2002) 1.00
Does nitric oxide allow endothelial cells to sense hypoxia and mediate hypoxic vasodilatation? In vivo and in vitro studies. J Physiol (2003) 1.00
GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo. Br J Pharmacol (2005) 1.00
Monitoring cytochrome redox changes in the mitochondria of intact cells using multi-wavelength visible light spectroscopy. Biochim Biophys Acta (2003) 0.99
Nitric oxide from inflammatory-activated glia synergizes with hypoxia to induce neuronal death. J Neurosci Res (2004) 0.96
Employment precariousness and poor mental health: evidence from Spain on a new social determinant of health. J Environ Public Health (2013) 0.95
Inhibition of mitochondrial respiration by the anticancer agent 2-methoxyestradiol. Biochem Biophys Res Commun (2004) 0.95
Antiplatelet properties of a novel, non-NO-based soluble guanylate cyclase activator, BAY 41-2272. Vascul Pharmacol (2003) 0.95
In the eye of the storm: mitochondrial damage during heart and brain ischaemia. FEBS J (2013) 0.94
Highly purified lipoteichoic acid induced pro-inflammatory signalling in primary culture of rat microglia through Toll-like receptor 2: selective potentiation of nitric oxide production by muramyl dipeptide. J Neurochem (2006) 0.94
Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia. J Biol Chem (2013) 0.94
The Employment Precariousness Scale (EPRES): psychometric properties of a new tool for epidemiological studies among waged and salaried workers. Occup Environ Med (2010) 0.93
Retracted Mitochondrial dysfunction and HIF1alpha stabilization in inflammation. J Cell Sci (2008) 0.92
Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt. Mol Pharmacol (2003) 0.91
Cytochrome c oxidase maintains mitochondrial respiration during partial inhibition by nitric oxide. J Cell Sci (2006) 0.91
Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells. J Neurochem (2013) 0.91
Increased expression of arginase II in patients with different forms of arthritis. Implications of the regulation of nitric oxide. J Rheumatol (2002) 0.89
Lactadherin/MFG-E8 is essential for microglia-mediated neuronal loss and phagoptosis induced by amyloid β. J Neurochem (2013) 0.88
Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release. J Biomed Sci (2009) 0.88
Employment precariousness in Spain: prevalence, social distribution, and population-attributable risk percent of poor mental health. Int J Health Serv (2011) 0.87
Nitric oxide and calcium together inactivate mitochondrial complex I and induce cytochrome c release. J Mol Cell Cardiol (2003) 0.87
Inhibition of UDP/P2Y6 purinergic signaling prevents phagocytosis of viable neurons by activated microglia in vitro and in vivo. Glia (2014) 0.87
Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression. J Neurochem (2002) 0.86
Characterization of the non-nitrergic NANC relaxation responses in the rabbit vaginal wall. Br J Pharmacol (2002) 0.86
Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53- and Bax-dependent pathways. J Neurochem (2004) 0.86
Elevated immunoglobulin E against recombinant Brugia malayi gamma-glutamyl transpeptidase in patients with bancroftian filariasis: association with tropical pulmonary eosinophilia or putative immunity. Infect Immun (2003) 0.86
Nitric oxide from neuronal nitric oxide synthase sensitises neurons to hypoxia-induced death via competitive inhibition of cytochrome oxidase. J Neurochem (2007) 0.85
Psychosocial factor exposures in the workplace: differences between immigrants and Spaniards. Eur J Public Health (2011) 0.85
Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival. Mol Cancer (2014) 0.84
The relationship between immigration and mental health: what is the role of workplace psychosocial factors. Int Arch Occup Environ Health (2011) 0.83
NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function. FASEB J (2002) 0.83
Anthocyanins block ischemia-induced apoptosis in the perfused heart and support mitochondrial respiration potentially by reducing cytosolic cytochrome c. Int J Biochem Cell Biol (2012) 0.82
Rotenone induces neuronal death by microglial phagocytosis of neurons. FEBS J (2013) 0.82
Nitric oxide and hypoxia. Essays Biochem (2007) 0.82
Psychosocial risk exposures and labour management practices. An exploratory approach. Scand J Public Health (2010) 0.82
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine. Free Radic Biol Med (2009) 0.81
Social inequalities in mortality in a retrospective cohort of civil servants in Barcelona. Int J Epidemiol (2003) 0.81
S-nitrosothiol-induced rapid cytochrome c release, caspase activation and mitochondrial permeability transition in perfused heart. Biochem Pharmacol (2003) 0.80
Inactivation of nitric oxide by cytochrome c oxidase under steady-state oxygen conditions. Biochim Biophys Acta (2009) 0.80
From pollutant gas to biological messenger: the diverse actions of nitric oxide in cancer. Ann R Coll Surg Engl (2002) 0.78