Published in Dev Cell on April 01, 2005
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev (2008) 4.38
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development (2007) 3.56
Vertebrate endoderm development and organ formation. Annu Rev Cell Dev Biol (2009) 2.67
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell (2009) 2.55
Wnt/β-catenin promotes gastric fundus specification in mice and humans. Nature (2017) 2.05
Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction. Nat Cell Biol (2008) 1.76
A dosage-dependent role for Spry2 in growth and patterning during palate development. Mech Dev (2007) 1.51
Stomach Organ and Cell Lineage Differentiation: from Embryogenesis to Adult Homeostasis. Cell Mol Gastroenterol Hepatol (2016) 1.46
Gastric epithelial stem cells. Gastroenterology (2010) 1.39
Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development (2010) 1.37
T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine. EMBO Rep (2007) 1.26
FGF10 signaling controls stomach morphogenesis. Dev Biol (2006) 1.23
Role of homeobox genes in the patterning, specification, and differentiation of ectodermal appendages in mammals. J Cell Physiol (2008) 1.21
Wnt signaling specifies and patterns intestinal endoderm. Mech Dev (2011) 1.14
Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. Gastroenterology (2009) 1.10
Cdx2 determines the fate of postnatal intestinal endoderm. Development (2011) 1.10
How to make an intestine. Development (2014) 1.10
barx1 is necessary for ectomesenchyme proliferation and osteochondroprogenitor condensation in the zebrafish pharyngeal arches. Dev Biol (2008) 1.03
Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation. PLoS One (2011) 1.00
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev Dyn (2010) 1.00
Dynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn (2009) 1.00
barx1 represses joints and promotes cartilage in the craniofacial skeleton. Development (2013) 0.99
Organoid Models of Human Gastrointestinal Development and Disease. Gastroenterology (2016) 0.92
Boundaries, junctions and transitions in the gastrointestinal tract. Exp Cell Res (2011) 0.90
H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model. Dis Model Mech (2013) 0.90
The use of murine-derived fundic organoids in studies of gastric physiology. J Physiol (2015) 0.90
Conditional expression of Wnt9b in Six2-positive cells disrupts stomach and kidney function. PLoS One (2012) 0.89
Epithelial BMP signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells. Am J Physiol Gastrointest Liver Physiol (2011) 0.89
Developmental stalling and organ-autonomous regulation of morphogenesis. Proc Natl Acad Sci U S A (2011) 0.89
Expression of pituitary homeobox 1 gene in human gastric carcinogenesis and its clinicopathological significance. World J Gastroenterol (2008) 0.89
Barx1 and evolutionary changes in feeding. J Anat (2005) 0.88
How form follows functional genomics: gene expression profiling gastric epithelial cells with a particular discourse on the parietal cell. Physiol Genomics (2009) 0.88
MAPKs and signal transduction in the control of gastrointestinal epithelial cell proliferation and differentiation. Int J Mol Sci (2013) 0.87
Oesophageal adenocarcinoma and gastric cancer: should we mind the gap? Nat Rev Cancer (2016) 0.87
Generation of stomach tissue from mouse embryonic stem cells. Nat Cell Biol (2015) 0.86
Wnt signaling in gut organogenesis. Organogenesis (2008) 0.86
Indian Hedgehog mediates gastrin-induced proliferation in stomach of adult mice. Gastroenterology (2014) 0.84
Going in circles: conserved mechanisms control radial patterning in the urinary and digestive tracts. J Clin Invest (2006) 0.84
LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3. BMC Biol (2014) 0.83
Downstream targets of GATA3 in the vestibular sensory organs of the inner ear. Dev Dyn (2009) 0.83
Specific inactivation of Twist1 in the mandibular arch neural crest cells affects the development of the ramus and reveals interactions with hand2. Dev Dyn (2012) 0.83
The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Mol Cell Biol (2015) 0.82
One shall become two: Separation of the esophagus and trachea from the common foregut tube. Dev Dyn (2014) 0.82
Gastrointestinal Fibroblasts Have Specialized, Diverse Transcriptional Phenotypes: A Comprehensive Gene Expression Analysis of Human Fibroblasts. PLoS One (2015) 0.81
Neuronal target identification requires AHA-1-mediated fine-tuning of Wnt signaling in C. elegans. PLoS Genet (2013) 0.81
Selective gene expression by rat gastric corpus epithelium. Physiol Genomics (2010) 0.80
Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium. Histochem Cell Biol (2011) 0.80
Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. PLoS One (2013) 0.79
Regulation of mouse stomach development and Barx1 expression by specific microRNAs. Development (2011) 0.79
Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme. Development (2011) 0.78
Mesenchymal-epithelial interactions during digestive tract development and epithelial stem cell regeneration. Cell Mol Life Sci (2015) 0.78
Gene-expression analysis of cementoblasts and osteoblasts. J Periodontal Res (2015) 0.78
Ontogeny of the mouse vocal fold epithelium. Dev Biol (2015) 0.78
Stomach development, stem cells and disease. Development (2016) 0.77
Cellular plasticity in the adult liver and stomach. J Physiol (2016) 0.76
Frogs as integrative models for understanding digestive organ development and evolution. Semin Cell Dev Biol (2016) 0.76
Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. PLoS One (2016) 0.75
Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1. Dev Biol (2015) 0.75
Unique Cellular Lineage Composition of the First Gland of the Mouse Gastric Corpus. J Histochem Cytochem (2016) 0.75
Loss of mesenchymal bone morphogenetic protein signaling leads to development of reactive stroma and initiation of the gastric neoplastic cascade. Sci Rep (2016) 0.75
Metaplasia: tissue injury adaptation and a precursor to the dysplasia-cancer sequence. Nat Rev Cancer (2017) 0.75
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature (2008) 6.24
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res (2011) 5.97
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell (2004) 4.98
Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab. Sci Transl Med (2011) 4.51
Dynamic visualization of thrombopoiesis within bone marrow. Science (2007) 4.35
An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science (2005) 3.61
Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev Cell (2010) 2.84
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res (2012) 2.26
Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. Blood (2008) 2.20
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet (2007) 2.18
Prominin1 (CD133) as an intestinal stem cell marker: promise and nuance. Gastroenterology (2009) 2.13
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Res (2009) 1.89
Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis. Nat Genet (2013) 1.87
Dual origin of mesenchymal stem cells contributing to organ growth and repair. Proc Natl Acad Sci U S A (2011) 1.77
Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood (2005) 1.76
Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev (2005) 1.73
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood (2007) 1.64
Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One (2008) 1.60
Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate. Nat Genet (2012) 1.60
Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells. Proc Natl Acad Sci U S A (2012) 1.58
p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A (2013) 1.57
Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology (2007) 1.55
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling. Sci Transl Med (2012) 1.54
Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis. Blood (2006) 1.52
Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development. Am J Hum Genet (2006) 1.50
Mechanisms of organelle transport and capture along proplatelets during platelet production. Blood (2005) 1.47
The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation. Blood (2009) 1.46
Neural crest contribution to mammalian tooth formation. Birth Defects Res C Embryo Today (2004) 1.44
Tooth and jaw: molecular mechanisms of patterning in the first branchial arch. Arch Oral Biol (2003) 1.44
Mechanisms and implications of platelet discoid shape. Blood (2003) 1.42
Platelets contribute to postnatal occlusion of the ductus arteriosus. Nat Med (2009) 1.41
Restriction of sonic hedgehog signalling during early tooth development. Development (2004) 1.40
Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease. Hum Mol Genet (2005) 1.39
Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer. Clin Cancer Res (2009) 1.39
Gastric epithelial stem cells. Gastroenterology (2010) 1.39
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Miner Res (2003) 1.39
Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development (2010) 1.37
Normal and abnormal dental development. Hum Mol Genet (2003) 1.33
Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo. Arthritis Rheum (2011) 1.33
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proc Natl Acad Sci U S A (2010) 1.32
A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development (2006) 1.32
Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell (2007) 1.31
Primary cilia regulate Shh activity in the control of molar tooth number. Development (2009) 1.31
Hierarchy revealed in the specification of three skeletal fates by Sox9 and Runx2. Dev Biol (2004) 1.29
Essential and redundant functions of caudal family proteins in activating adult intestinal genes. Mol Cell Biol (2011) 1.25
Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression. J Biol Chem (2011) 1.24
Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling. Cancer Res (2012) 1.23
Targeting PI3K signaling as a therapeutic approach for colorectal cancer. Gastroenterology (2011) 1.22
Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog. J Clin Invest (2007) 1.22
Notch signaling in stomach epithelial stem cell homeostasis. J Exp Med (2011) 1.20
Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes. Mol Cell Biol (2002) 1.20
Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. Mol Cell Biol (2004) 1.19
The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons. Nucleic Acids Res (2011) 1.18
Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn (2004) 1.18
Stem cell-based biological tooth repair and regeneration. Trends Cell Biol (2010) 1.17
Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding. Mol Cell Biol (2012) 1.15
Mouse models of tooth abnormalities. Eur J Oral Sci (2008) 1.14
Role of Islet1 in the patterning of murine dentition. Development (2003) 1.14
Regeneration of teeth using stem cell-based tissue engineering. Expert Opin Biol Ther (2006) 1.13
A role for Rab27b in NF-E2-dependent pathways of platelet formation. Blood (2003) 1.11
Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome. Dev Dyn (2009) 1.11
Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development (2004) 1.11
Expression of Axin2 indicates a role for canonical Wnt signaling in development of the crown and root during pre- and postnatal tooth development. Dev Dyn (2010) 1.10
Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. Gastroenterology (2009) 1.10
Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development (2007) 1.09
Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome. Hum Mol Genet (2008) 1.08
The Ectodysplasin and NFkappaB signalling pathways in odontogenesis. Arch Oral Biol (2005) 1.08
High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss. Genes Chromosomes Cancer (2008) 1.08
Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen. Proc Natl Acad Sci U S A (2005) 1.07
RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. J Biol Chem (2008) 1.06
Sonic hedgehog in the pharyngeal endoderm controls arch pattern via regulation of Fgf8 in head ectoderm. Dev Biol (2006) 1.05
Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis. J Exp Zool B Mol Dev Evol (2009) 1.04
Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity. Proc Natl Acad Sci U S A (2010) 1.03
The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Dev Biol (2009) 1.03
Tissue engineering of teeth using adult stem cells. Arch Oral Biol (2005) 1.02
Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol (2009) 1.02
Stem cells and tooth tissue engineering. Cell Tissue Res (2007) 1.01
Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation. PLoS One (2011) 1.00
Perivascular cells as mesenchymal stem cells. Expert Opin Biol Ther (2010) 0.99
Making up the numbers: The molecular control of mammalian dental formula. Semin Cell Dev Biol (2010) 0.98
Contribution of mesoderm to the developing dental papilla. Int J Dev Biol (2011) 0.98
Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells. Gastroenterology (2008) 0.98
Intergenic enhancers with distinct activities regulate Dlx gene expression in the mesenchyme of the branchial arches. Dev Biol (2004) 0.98
Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol (2009) 0.97
Overlapping gene expression in fetal mouse intestine development and human colorectal cancer. Cancer Res (2005) 0.97
Coordination of epithelial branching and salivary gland lumen formation by Wnt and FGF signals. Dev Biol (2011) 0.97
Regionalisation of early head ectoderm is regulated by endoderm and prepatterns the orofacial epithelium. Development (2004) 0.96
The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms. BMC Genomics (2007) 0.95
Expression and regulation of the Msx1 natural antisense transcript during development. Nucleic Acids Res (2005) 0.95
A dual role for Ikk alpha in tooth development. Dev Cell (2004) 0.95
Ring1a/b polycomb proteins regulate the mesenchymal stem cell niche in continuously growing incisors. Dev Biol (2012) 0.95