Published in Organogenesis on April 01, 2008
Pronephric tubulogenesis requires Daam1-mediated planar cell polarity signaling. J Am Soc Nephrol (2011) 1.55
Wnt signaling specifies and patterns intestinal endoderm. Mech Dev (2011) 1.14
Interplay between Wnt2 and Wnt2bb controls multiple steps of early foregut-derived organ development. Development (2011) 1.01
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev Dyn (2010) 1.00
Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev Biol (2013) 0.92
Anti-inflammatory activity of Wnt signaling in enteric nervous system: in vitro preliminary evidences in rat primary cultures. J Neuroinflammation (2015) 0.88
Sfrp5 modulates both Wnt and BMP signaling and regulates gastrointestinal organogenesis [corrected] in the zebrafish, Danio rerio. PLoS One (2013) 0.85
Genome-wide analysis of DNA methylation and gene expression defines molecular characteristics of Crohn's disease-associated fibrosis. Clin Epigenetics (2016) 0.81
Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma. Hum Pathol (2012) 0.80
Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice. PLoS One (2012) 0.77
Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. PLoS One (2016) 0.75
Wnt/beta-catenin signaling in development and disease. Cell (2006) 30.09
Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature (2007) 29.32
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell (2002) 13.92
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Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development (1999) 9.82
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development (1996) 9.58
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell (2002) 8.08
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science (2001) 7.17
Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem (2006) 6.32
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev (2003) 6.27
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev (2004) 5.66
Organizing cell renewal in the intestine: stem cells, signals and combinatorial control. Nat Rev Genet (2006) 4.82
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc Natl Acad Sci U S A (2003) 4.76
Mitogenic influence of human R-spondin1 on the intestinal epithelium. Science (2005) 4.58
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J Cell Biol (2007) 4.52
Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol (2005) 4.34
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology (2007) 4.17
Expression pattern of Wnt signaling components in the adult intestine. Gastroenterology (2005) 4.09
Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicol Sci (2004) 3.85
Mesodermal Wnt2b signalling positively regulates liver specification. Nature (2006) 3.69
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Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev (2001) 3.04
Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev (2005) 2.94
Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis. Gastroenterology (2007) 2.79
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Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. J Biol (2004) 2.71
Wnt signaling regulates pancreatic beta cell proliferation. Proc Natl Acad Sci U S A (2007) 2.61
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine. Development (2005) 2.56
Conditional deletion of beta-catenin reveals its role in liver growth and regeneration. Gastroenterology (2006) 2.54
Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development (2007) 2.50
Beta-catenin is essential for pancreatic acinar but not islet development. Development (2005) 2.38
Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes. Cancer Res (2002) 2.05
The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling. Dev Cell (2005) 1.90
Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development. Curr Biol (2005) 1.87
The canonical Wnt signalling pathway and its APC partner in colon cancer development. Gut (2006) 1.86
Live and let die in the intestinal epithelium. Curr Opin Cell Biol (2003) 1.85
Cellular and molecular aspects of gastric cancer. World J Gastroenterol (2006) 1.84
Beta-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification. Gastroenterology (2003) 1.78
Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (2007) 1.66
Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn (2002) 1.61
Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver. Gastroenterology (2005) 1.58
Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology (2007) 1.55
Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells. Genes Dev (2005) 1.52
Deciphering the underlying genetic and epigenetic events leading to gastric carcinogenesis. J Cell Physiol (2007) 1.47
beta-Catenin is critical for early postnatal liver growth. Am J Physiol Gastrointest Liver Physiol (2007) 1.45
Wnt signaling during development of the gastrointestinal tract. Dev Biol (2003) 1.44
The making of Wnt: new insights into Wnt maturation, sorting and secretion. Development (2006) 1.39
Paneth cells: their role in innate immunity and inflammatory disease. Gut (2005) 1.32
Expression patterns of Wnt genes in mouse gut development. Mech Dev (2001) 1.27
Wnt impacts growth and differentiation in ex vivo liver development. Exp Cell Res (2004) 1.23
No organ left behind: tales of gut development and evolution. Science (2005) 1.16
Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation. Dev Biol (2004) 1.14
Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development (2007) 1.09
Wnt signalling in the mouse intestine. Oncogene (2006) 1.08
Expression and function of Wnt5a in the development of the glandular stomach in the chicken embryo. Dev Growth Differ (2006) 0.87
Microbiology: Gut defence. Nature (2003) 0.81
Zebrafish and the understanding of liver development: the emerging role of the Wnt pathway in liver biology. Hepatology (2007) 0.81
Wnt signaling components in the chicken intestinal tract. Dev Biol (2003) 0.80
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature (2008) 6.24
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res (2011) 5.97
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell (2004) 4.98
Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab. Sci Transl Med (2011) 4.51
Dynamic visualization of thrombopoiesis within bone marrow. Science (2007) 4.35
Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev Cell (2010) 2.84
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res (2012) 2.26
Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. Blood (2008) 2.20
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet (2007) 2.18
Prominin1 (CD133) as an intestinal stem cell marker: promise and nuance. Gastroenterology (2009) 2.13
The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling. Dev Cell (2005) 1.90
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Res (2009) 1.89
Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood (2005) 1.76
Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev (2005) 1.73
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood (2007) 1.64
Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells. Proc Natl Acad Sci U S A (2012) 1.58
p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A (2013) 1.57
Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology (2007) 1.55
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling. Sci Transl Med (2012) 1.54
Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis. Blood (2006) 1.52
Mechanisms of organelle transport and capture along proplatelets during platelet production. Blood (2005) 1.47
The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation. Blood (2009) 1.46
Mechanisms and implications of platelet discoid shape. Blood (2003) 1.42
Platelets contribute to postnatal occlusion of the ductus arteriosus. Nat Med (2009) 1.41
Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer. Clin Cancer Res (2009) 1.39
Gastric epithelial stem cells. Gastroenterology (2010) 1.39
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Miner Res (2003) 1.39
Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development (2010) 1.37
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proc Natl Acad Sci U S A (2010) 1.32
A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development (2006) 1.32
Essential and redundant functions of caudal family proteins in activating adult intestinal genes. Mol Cell Biol (2011) 1.25
Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression. J Biol Chem (2011) 1.24
Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling. Cancer Res (2012) 1.23
Targeting PI3K signaling as a therapeutic approach for colorectal cancer. Gastroenterology (2011) 1.22
Notch signaling in stomach epithelial stem cell homeostasis. J Exp Med (2011) 1.20
Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes. Mol Cell Biol (2002) 1.20
Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. Mol Cell Biol (2004) 1.19
The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons. Nucleic Acids Res (2011) 1.18
Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding. Mol Cell Biol (2012) 1.15
A role for Rab27b in NF-E2-dependent pathways of platelet formation. Blood (2003) 1.11
Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development (2004) 1.11
Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. Gastroenterology (2009) 1.10
Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development (2007) 1.09
Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome. Hum Mol Genet (2008) 1.08
High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss. Genes Chromosomes Cancer (2008) 1.08
RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. J Biol Chem (2008) 1.06
Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation. PLoS One (2011) 1.00
Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells. Gastroenterology (2008) 0.98
Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol (2009) 0.97
Overlapping gene expression in fetal mouse intestine development and human colorectal cancer. Cancer Res (2005) 0.97
Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum. Mol Cell Biol (2008) 0.94
Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX. J Biol Chem (2013) 0.92
Molecular mechanisms of megakaryocyte differentiation. Semin Thromb Hemost (2004) 0.92
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Mol Cell Biol (2004) 0.91
Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. Cell Metab (2007) 0.91
Boundaries, junctions and transitions in the gastrointestinal tract. Exp Cell Res (2011) 0.90
The use of murine-derived fundic organoids in studies of gastric physiology. J Physiol (2015) 0.90
Expression and function of Nkx6.3 in vertebrate hindbrain. Brain Res (2008) 0.88
Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulation. J Biol Chem (2002) 0.86
Requirement of the epithelium-specific Ets transcription factor Spdef for mucous gland cell function in the gastric antrum. J Biol Chem (2010) 0.86
Stem cells: The intestinal-crypt casino. Nature (2010) 0.81
Regulation of mouse stomach development and Barx1 expression by specific microRNAs. Development (2011) 0.79
Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme. Development (2011) 0.78
DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions. Mol Cell Biol (2013) 0.77
Stem cell niches: famished Paneth cells, gluttonous stem cells. Curr Biol (2012) 0.75