Published in Genome Res on January 07, 2009
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FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat Genet (2010) 5.22
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Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis. EMBO J (2011) 2.66
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Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria. Elife (2014) 1.13
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FoxA1 is a key mediator of hormonal response in breast and prostate cancer. Front Endocrinol (Lausanne) (2012) 1.02
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The forkhead transcription factor FOXK2 promotes AP-1-mediated transcriptional regulation. Mol Cell Biol (2011) 0.96
Emerging patterns of epigenomic variation. Trends Genet (2011) 0.95
Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells. Proc Natl Acad Sci U S A (2011) 0.93
Chromatin remodeling mediated by the FOXA1/A2 transcription factors activates CFTR expression in intestinal epithelial cells. Epigenetics (2014) 0.91
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Interrogating genomic and epigenomic data to understand prostate cancer. Biochim Biophys Acta (2012) 0.85
Current perspectives on FOXA1 regulation of androgen receptor signaling and prostate cancer. Genes Dis (2015) 0.84
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Androgen receptor genomic regulation. Transl Androl Urol (2013) 0.79
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A novel DNA sequence motif in human and mouse genomes. Sci Rep (2015) 0.75
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Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet (2005) 29.45
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The complex language of chromatin regulation during transcription. Nature (2007) 16.97
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High-resolution mapping and characterization of open chromatin across the genome. Cell (2008) 15.93
Dynamic regulation of nucleosome positioning in the human genome. Cell (2008) 15.60
An extended transcriptional network for pluripotency of embryonic stem cells. Cell (2008) 14.64
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FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell (2008) 14.18
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In vivo enhancer analysis of human conserved non-coding sequences. Nature (2006) 10.60
Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell (2003) 10.42
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FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin. Genome Res (2006) 7.72
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature (2007) 7.04
Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome. Genome Res (2006) 6.54
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A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell (2007) 5.99
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Whole-genome cartography of estrogen receptor alpha binding sites. PLoS Genet (2007) 5.85
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Histone arginine methylation regulates pluripotency in the early mouse embryo. Nature (2007) 4.55
Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. Mol Cell (2006) 4.51
From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response. Proc Natl Acad Sci U S A (2005) 4.16
The initiation of liver development is dependent on Foxa transcription factors. Nature (2005) 3.88
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The Foxa family of transcription factors in development and metabolism. Cell Mol Life Sci (2006) 3.47
Interaction of the glucocorticoid receptor with the chromatin landscape. Mol Cell (2008) 3.42
Cell cycle-specified fluctuation of nucleosome occupancy at gene promoters. PLoS Genet (2006) 3.08
The role of hepatocyte nuclear factor-3 alpha (Forkhead Box A1) and androgen receptor in transcriptional regulation of prostatic genes. Mol Endocrinol (2003) 3.01
A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members. Genome Res (2007) 2.97
Cell- and gene-specific regulation of primary target genes by the androgen receptor. Genes Dev (2007) 2.96
Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Res (2007) 2.95
Methylation at arginine 17 of histone H3 is linked to gene activation. EMBO Rep (2001) 2.83
Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. EMBO J (1998) 2.81
A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes Dev (2006) 2.76
Predicting tissue-specific enhancers in the human genome. Genome Res (2007) 2.72
Genomewide demarcation of RNA polymerase II transcription units revealed by physical fractionation of chromatin. Proc Natl Acad Sci U S A (2003) 2.33
Unique ERalpha cistromes control cell type-specific gene regulation. Mol Endocrinol (2008) 2.19
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Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression. Mol Syst Biol (2008) 1.89
CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1. Cancer Res (2008) 1.83
Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc Natl Acad Sci U S A (2007) 1.81
The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation. Mol Cell Biol (2006) 1.55
A genome-wide analysis in Saccharomyces cerevisiae demonstrates the influence of chromatin modifiers on transcription. Nat Genet (2007) 1.53
Genome-wide identification of estrogen receptor alpha-binding sites in mouse liver. Mol Endocrinol (2007) 1.50
Developmental control via GATA factor interplay at chromatin domains. J Cell Physiol (2005) 1.46
Using ChIP-chip technology to reveal common principles of transcriptional repression in normal and cancer cells. Genome Res (2008) 1.45
CCCTC-binding factor confines the distal action of estrogen receptor. Cancer Res (2008) 1.04
GATA-1 modulates the chromatin structure and activity of the chicken alpha-globin 3' enhancer. Mol Cell Biol (2007) 0.89
Integrative genome-wide expression analysis bears evidence of estrogen receptor-independent transcription in heregulin-stimulated MCF-7 cells. PLoS One (2008) 0.81
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Genome-wide analysis of estrogen receptor binding sites. Nat Genet (2006) 18.63
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Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res (2012) 9.13
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature (2010) 8.87
Differential chromatin marking of introns and expressed exons by H3K36me3. Nat Genet (2009) 8.11
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature (2011) 7.43
Model-based analysis of two-color arrays (MA2C). Genome Biol (2007) 7.28
X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell (2006) 7.17
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell (2009) 7.09
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet (2009) 6.99
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature (2008) 6.24
Molecular determinants for the tissue specificity of SERMs. Science (2002) 6.20
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell (2007) 5.99
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res (2011) 5.97
Nucleosome dynamics define transcriptional enhancers. Nat Genet (2010) 5.94
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science (2011) 5.91
Chromatin structure analyses identify miRNA promoters. Genes Dev (2008) 5.40
Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking. Mol Cell (2005) 5.38
High-throughput mapping of the chromatin structure of human promoters. Nat Biotechnol (2007) 5.24
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell (2004) 4.98
Formation of the androgen receptor transcription complex. Mol Cell (2002) 4.93
PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale. Genes Dev (2008) 4.83
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Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab. Sci Transl Med (2011) 4.51
The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. J Clin Invest (2011) 4.41
Dynamic visualization of thrombopoiesis within bone marrow. Science (2007) 4.35
CEAS: cis-regulatory element annotation system. Bioinformatics (2009) 4.26
Cistrome: an integrative platform for transcriptional regulation studies. Genome Biol (2011) 4.13
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res (2008) 4.08
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (2012) 3.74
Chromatin marks identify critical cell types for fine mapping complex trait variants. Nat Genet (2012) 3.67
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. J Natl Cancer Inst (2008) 3.55
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p63 regulates an adhesion programme and cell survival in epithelial cells. Nat Cell Biol (2006) 3.37
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A hidden Markov model for analyzing ChIP-chip experiments on genome tiling arrays and its application to p53 binding sequences. Bioinformatics (2005) 3.06
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Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Res (2007) 2.95
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nat Genet (2012) 2.86
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell (2011) 2.86
Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev Cell (2010) 2.84
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Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development. Development (2004) 2.68
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Chromatin signature of embryonic pluripotency is established during genome activation. Nature (2010) 2.64
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Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature (2008) 2.51
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Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Res (2009) 2.27
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Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer Cell (2011) 2.23
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