Published in Gastroenterology on May 03, 2007
Intestinal development and differentiation. Exp Cell Res (2011) 1.44
Wnt5a is essential for intestinal elongation in mice. Dev Biol (2008) 1.41
Vertebrate intestinal endoderm development. Dev Dyn (2011) 1.41
Gastric epithelial stem cells. Gastroenterology (2010) 1.39
Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development (2011) 1.18
Developmental switch of intestinal antimicrobial peptide expression. J Exp Med (2008) 1.11
Lrp5 and Lrp6 play compensatory roles in mouse intestinal development. J Cell Biochem (2012) 1.10
Wnt signaling in lung organogenesis. Organogenesis (2008) 1.06
Intestinal mucosal atrophy and adaptation. World J Gastroenterol (2012) 1.06
Wnt/beta-catenin signaling in hepatic organogenesis. Organogenesis (2008) 1.05
Cdx2 levels modulate intestinal epithelium maturity and Paneth cell development. Gastroenterology (2010) 1.05
Intestinal stem cells. Curr Gastroenterol Rep (2010) 1.03
Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the β-catenin/TCF complex association via FOXO3a activation. Oncotarget (2015) 1.01
Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo. Stem Cell Reports (2014) 1.01
Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles. Mol Nutr Food Res (2014) 1.00
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev Dyn (2010) 1.00
Dynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn (2009) 1.00
Genetic control of intestinal stem cell specification and development: a comparative view. Stem Cell Rev (2012) 0.93
Boundaries, junctions and transitions in the gastrointestinal tract. Exp Cell Res (2011) 0.90
Transcriptional networks in liver and intestinal development. Cold Spring Harb Perspect Biol (2012) 0.89
Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis. Dev Biol (2010) 0.89
Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine. Am J Pathol (2009) 0.88
Wnt signaling in gut organogenesis. Organogenesis (2008) 0.86
Wound healing in development. Birth Defects Res C Embryo Today (2012) 0.83
Recent advances in small bowel diseases: Part I. World J Gastroenterol (2012) 0.79
Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations. Cell Death Differ (2014) 0.79
Developmental expression of Eph and ephrin family genes in mammalian small intestine. Dig Dis Sci (2010) 0.78
Adult onset lung disease following transient disruption of fetal stretch-induced differentiation. Respir Res (2009) 0.78
A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells. Stem Cell Reports (2016) 0.77
Intestinal development: the many faces of Wnt signaling. Gastroenterology (2007) 0.77
Update on small intestinal stem cells. World J Gastroenterol (2013) 0.77
Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice. PLoS One (2012) 0.77
Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts. Dev Dyn (2016) 0.76
Plant derived edible nanoparticles as a new therapeutic approach against diseases. Tissue Barriers (2016) 0.76
Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. PLoS One (2016) 0.75
A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development (2016) 0.75
Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane. BMC Cancer (2009) 0.75
High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med (2002) 11.28
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell (2005) 6.90
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature (2008) 6.24
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res (2011) 5.97
Subtypes of medulloblastoma have distinct developmental origins. Nature (2010) 5.94
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell (2004) 4.98
Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev (2004) 4.78
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell (2008) 4.68
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. Cell (2012) 4.58
Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab. Sci Transl Med (2011) 4.51
Dynamic visualization of thrombopoiesis within bone marrow. Science (2007) 4.35
Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol (2005) 4.34
Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell (2011) 4.04
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. Nat Immunol (2006) 3.98
Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev (2004) 3.83
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
Wnt/beta-catenin signaling controls development of the blood-brain barrier. J Cell Biol (2008) 3.22
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18
Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Dev Biol (2006) 3.17
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J (2002) 3.06
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol (2003) 2.85
Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev Cell (2010) 2.84
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science (2004) 2.82
Wnt signaling regulates pancreatic beta cell proliferation. Proc Natl Acad Sci U S A (2007) 2.61
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A (2007) 2.56
ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J Cell Biol (2005) 2.50
Stabilization of beta-catenin impacts pancreas growth. Development (2006) 2.44
Wnt-beta-catenin signaling initiates taste papilla development. Nat Genet (2006) 2.43
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J Cell Sci (2007) 2.41
Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell (2006) 2.40
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat Genet (2007) 2.39
Dclk1 distinguishes between tumor and normal stem cells in the intestine. Nat Genet (2012) 2.33
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res (2012) 2.26
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. Blood (2008) 2.20
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet (2007) 2.18
Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell (2013) 2.17
β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell (2011) 2.17
Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm. Dev Cell (2002) 2.14
Prominin1 (CD133) as an intestinal stem cell marker: promise and nuance. Gastroenterology (2009) 2.13
Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. J Clin Invest (2007) 2.12
Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death. Mol Cell Biol (2003) 2.07
Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice. Cancer Res (2002) 2.05
Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice. Proc Natl Acad Sci U S A (2008) 2.04
Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis. Nat Neurosci (2009) 2.03
Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. Cancer Res (2004) 2.01
The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell (2010) 2.01
Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps. Cancer Res (2002) 2.00
Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice. Nat Genet (2003) 1.99
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96
Wnt signals mediate a fate decision between otic placode and epidermis. Development (2006) 1.94
Beta-catenin regulates differentiation of respiratory epithelial cells in vivo. Am J Physiol Lung Cell Mol Physiol (2005) 1.93
The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling. Dev Cell (2005) 1.90
Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal. Hum Mol Genet (2008) 1.90
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Res (2009) 1.89
Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. Hum Mol Genet (2008) 1.80
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol (2004) 1.77
Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood (2005) 1.76
Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development (2003) 1.73
Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev (2005) 1.73
Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling. Eur J Neurosci (2004) 1.71
Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol (2005) 1.66
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood (2007) 1.64
Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development (2007) 1.63
Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res (2002) 1.62
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell (2009) 1.61
Wt1 negatively regulates beta-catenin signaling during testis development. Development (2008) 1.61
JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Δ716) mice. Gastroenterology (2011) 1.61
Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.60
Stromal fibroblasts activated by tumor cells promote angiogenesis in mouse gastric cancer. J Biol Chem (2008) 1.60
Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice. Cancer Res (2002) 1.60
Homozygous inactivation of Sox9 causes complete XY sex reversal in mice. Biol Reprod (2005) 1.59
Modulation of synaptic plasticity by physiological activation of M1 muscarinic acetylcholine receptors in the mouse hippocampus. J Neurosci (2005) 1.58
Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells. Proc Natl Acad Sci U S A (2012) 1.58
Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. J Biol Chem (2001) 1.57
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2011) 1.57
p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A (2013) 1.57
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55
β-Catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche. Science (2014) 1.55
Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Proc Natl Acad Sci U S A (2012) 1.54
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling. Sci Transl Med (2012) 1.54
Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis. Blood (2006) 1.52
Mice lacking M2 and M3 muscarinic acetylcholine receptors are devoid of cholinergic smooth muscle contractions but still viable. J Neurosci (2002) 1.51
Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. J Biol Chem (2011) 1.51
Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development. Cancer Res (2005) 1.51
Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast. Development (2004) 1.50
Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. Gastroenterology (2006) 1.47
Mechanisms of organelle transport and capture along proplatelets during platelet production. Blood (2005) 1.47
Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling. Gastroenterology (2009) 1.47
The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation. Blood (2009) 1.46
Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc Natl Acad Sci U S A (2002) 1.44
Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice. EMBO J (2004) 1.42
Mechanisms and implications of platelet discoid shape. Blood (2003) 1.42
A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation. Dev Biol (2008) 1.42
Platelets contribute to postnatal occlusion of the ductus arteriosus. Nat Med (2009) 1.41
Gastric epithelial stem cells. Gastroenterology (2010) 1.39
Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer. Clin Cancer Res (2009) 1.39