Published in J Am Chem Soc on October 03, 2007
Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl (2009) 8.15
Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation. Angew Chem Int Ed Engl (2009) 3.81
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides. Chem Soc Rev (2010) 2.68
Labeling live cells by copper-catalyzed alkyne--azide click chemistry. Bioconjug Chem (2010) 1.86
Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications. J Am Chem Soc (2010) 1.56
Click chemistry in complex mixtures: bioorthogonal bioconjugation. Chem Biol (2014) 1.40
Organic synthesis "on water". Chem Rev (2009) 1.37
Core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and clicking-to. J Am Chem Soc (2010) 1.26
Direct evidence of a dinuclear copper intermediate in Cu(I)-catalyzed azide-alkyne cycloadditions. Science (2013) 1.24
Cu(I)-catalyzed diamination of conjugated dienes. Complementary regioselectivity from two distinct mechanistic pathways involving Cu(II) and Cu(III) species. J Am Chem Soc (2011) 1.03
CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum. J Am Chem Soc (2015) 0.98
Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Curr Protoc Chem Biol (2011) 0.98
Peptide cyclization and cyclodimerization by Cu(I)-mediated azide-alkyne cycloaddition. J Org Chem (2009) 0.97
Preparation of 18F-labeled peptides using the copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition. Nat Protoc (2011) 0.97
Surface functionalization of virus-like particles by direct conjugation using azide-alkyne click chemistry. Bioconjug Chem (2011) 0.95
Experimental investigation on the mechanism of chelation-assisted, copper(II) acetate-accelerated azide-alkyne cycloaddition. J Am Chem Soc (2011) 0.91
Advancements in the mechanistic understanding of the copper-catalyzed azide-alkyne cycloaddition. Beilstein J Org Chem (2013) 0.91
Chelation-assisted, copper(II)-acetate-accelerated azide-alkyne cycloaddition. J Org Chem (2010) 0.91
Methods to monitor classical protein-tyrosine phosphatase oxidation. FEBS J (2012) 0.90
"Clickable", polymerized liposomes as a versatile and stable platform for rapid optimization of their peripheral compositions. Chem Commun (Camb) (2010) 0.87
Synthetic aptamer-polymer hybrid constructs for programmed drug delivery into specific target cells. J Am Chem Soc (2014) 0.87
Biofunctionalization on alkylated silicon substrate surfaces via "click" chemistry. J Am Chem Soc (2010) 0.84
Polymer immobilized Cu(I) formation and azide-alkyne cycloaddition: A one pot reaction. Sci Rep (2015) 0.82
Relative performance of alkynes in copper-catalyzed azide-alkyne cycloaddition. Bioconjug Chem (2013) 0.81
Kinetics of bulk photo-initiated copper(i)-catalyzed azide-alkyne cycloaddition (CuAAC) polymerizations. Polym Chem (2015) 0.81
Controlled loadings in a mesoporous material: click-on silica. J Am Chem Soc (2008) 0.77
Resin-supported catalysts for CuAAC click reactions in aqueous or organic solvents. ACS Comb Sci (2012) 0.77
Discrete complexes immobilized onto click-SBA-15 silica: controllable loadings and the impact of surface coverage on catalysis. J Am Chem Soc (2012) 0.76
A Kinetic Self-Sorting Approach to Heterocircuit [3]Rotaxanes. Angew Chem Int Ed Engl (2016) 0.76
Ion-pair recognition by a neutral [2]rotaxane based on a bis-calix[4]pyrrole cyclic component. Chem Sci (2016) 0.75
Crystal structure of N,N,N-tris-[(1,3-benzo-thia-zol-2-yl)meth-yl]amine. Acta Crystallogr E Crystallogr Commun (2015) 0.75
Towards understanding the kinetic behaviour and limitations in photo-induced copper(i) catalyzed azide-alkyne cycloaddition (CuAAC) reactions. Phys Chem Chem Phys (2016) 0.75
Light-Activated Staudinger-Bertozzi Ligation within Living Animals. J Am Chem Soc (2016) 0.75
Computational studies on the regioselectivity of metal-catalyzed synthesis of 1,2,3 triazoles via click reaction: a review. J Mol Model (2015) 0.75
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. Angew Chem Int Ed Engl (2002) 24.12
Polytriazoles as copper(I)-stabilizing ligands in catalysis. Org Lett (2004) 5.49
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. J Am Chem Soc (2003) 5.34
Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation. Angew Chem Int Ed Engl (2009) 3.81
Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks. Angew Chem Int Ed Engl (2002) 3.06
Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates. J Am Chem Soc (2005) 2.75
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides. Chem Soc Rev (2010) 2.68
Mechanism of the ligand-free CuI-catalyzed azide-alkyne cycloaddition reaction. Angew Chem Int Ed Engl (2005) 2.62
Ruthenium-catalyzed cycloaddition of alkynes and organic azides. J Am Chem Soc (2005) 2.35
"On water": unique reactivity of organic compounds in aqueous suspension. Angew Chem Int Ed Engl (2005) 2.21
Efficiency and fidelity in a click-chemistry route to triazole dendrimers by the copper(i)-catalyzed ligation of azides and alkynes. Angew Chem Int Ed Engl (2004) 2.11
Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes. Angew Chem Int Ed Engl (2009) 2.10
Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching. J Am Chem Soc (2004) 1.89
Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles. J Am Chem Soc (2008) 1.86
Labeling live cells by copper-catalyzed alkyne--azide click chemistry. Bioconjug Chem (2010) 1.86
Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles. J Am Chem Soc (2009) 1.85
Accelerated bioorthogonal conjugation: a practical method for the ligation of diverse functional molecules to a polyvalent virus scaffold. Bioconjug Chem (2005) 1.84
Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism. J Am Chem Soc (2008) 1.76
A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly. Proc Natl Acad Sci U S A (2005) 1.72
Folic acid-mediated targeting of cowpea mosaic virus particles to tumor cells. Chem Biol (2007) 1.70
Label-free quantification of membrane-ligand interactions using backscattering interferometry. Nat Biotechnol (2011) 1.67
Iterative in situ click chemistry creates antibody-like protein-capture agents. Angew Chem Int Ed Engl (2009) 1.64
Natural supramolecular building blocks. Wild-type cowpea mosaic virus. Chem Biol (2002) 1.64
Viral MRI contrast agents: coordination of Gd by native virions and attachment of Gd complexes by azide-alkyne cycloaddition. Chem Commun (Camb) (2007) 1.63
Inhibitors of HIV-1 protease by using in situ click chemistry. Angew Chem Int Ed Engl (2006) 1.63
Global structural changes in hepatitis B virus capsids induced by the assembly effector HAP1. J Virol (2006) 1.59
Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications. J Am Chem Soc (2010) 1.56
Crosslinking of and coupling to viral capsid proteins by tyrosine oxidation. Chem Biol (2004) 1.55
Designing facial amphiphiles for the stabilization of integral membrane proteins. Angew Chem Int Ed Engl (2007) 1.55
Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem (2008) 1.54
Systemic trafficking of plant virus nanoparticles in mice via the oral route. Virology (2005) 1.53
Bio-distribution, toxicity and pathology of cowpea mosaic virus nanoparticles in vivo. J Control Release (2007) 1.53
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry. J Am Chem Soc (2003) 1.53
Benzimidazole and related ligands for Cu-catalyzed azide-alkyne cycloaddition. J Am Chem Soc (2007) 1.50
Icosahedral virus particles as addressable nanoscale building blocks. Angew Chem Int Ed Engl (2002) 1.49
Synthesis and reactivity of rhodium(II) N-triflyl azavinyl carbenes. J Am Chem Soc (2010) 1.45
Hybrid virus-polymer materials. 1. Synthesis and properties of PEG-decorated cowpea mosaic virus. Biomacromolecules (2003) 1.42
Plasma clearance of bacteriophage Qbeta particles as a function of surface charge. J Am Chem Soc (2008) 1.41
In situ click chemistry: probing the binding landscapes of biological molecules. Chem Soc Rev (2010) 1.38
Organic synthesis "on water". Chem Rev (2009) 1.37
Thiol-selective fluorogenic probes for labeling and release. J Am Chem Soc (2009) 1.36
Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus life cycle. J Virol (2008) 1.34
Direct human cartilage repair using three-dimensional bioprinting technology. Tissue Eng Part A (2012) 1.33
Multivalent, bifunctional dendrimers prepared by click chemistry. Chem Commun (Camb) (2005) 1.32
Functional virus-based polymer-protein nanoparticles by atom transfer radical polymerization. J Am Chem Soc (2011) 1.30
The allylic azide rearrangement: achieving selectivity. J Am Chem Soc (2005) 1.30
Natural supramolecular building blocks. Cysteine-added mutants of cowpea mosaic virus. Chem Biol (2002) 1.29
Practical synthesis of amides from in situ generated copper(I) acetylides and sulfonyl azides. Angew Chem Int Ed Engl (2006) 1.29
Chemical modification of viruses and virus-like particles. Curr Top Microbiol Immunol (2009) 1.28
Core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and clicking-to. J Am Chem Soc (2010) 1.26
On-virus construction of polyvalent glycan ligands for cell-surface receptors. J Am Chem Soc (2008) 1.26
Multivalent display and receptor-mediated endocytosis of transferrin on virus-like particles. Chembiochem (2010) 1.24
Click chemistry: function follows form. Chem Soc Rev (2010) 1.23
Head-to-tail peptide cyclodimerization by copper-catalyzed azide-alkyne cycloaddition. Angew Chem Int Ed Engl (2005) 1.23
Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes. J Am Chem Soc (2011) 1.22
Trapping of hepatitis B virus capsid assembly intermediates by phenylpropenamide assembly accelerators. ACS Chem Biol (2010) 1.21
Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds. Chem Biol (2010) 1.21
Efficient synthesis of 1-sulfonyl-1,2,3-triazoles. Org Lett (2010) 1.19
Microscale NMR screening of new detergents for membrane protein structural biology. J Am Chem Soc (2008) 1.18
Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases. J Biol Chem (2012) 1.18
Porous silicon as a versatile platform for laser desorption/ionization mass spectrometry. Anal Chem (2001) 1.16
Ruthenium-catalyzed cycloaddition of aryl azides and alkynes. Org Lett (2007) 1.16
Efficient synthesis of 2-substituted-1,2,3-triazoles. Org Lett (2008) 1.15
One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from in situ generated azides. Org Lett (2004) 1.14
Copper-catalyzed synthesis of N-sulfonyl-1,2,3-triazoles: controlling selectivity. Angew Chem Int Ed Engl (2007) 1.14
New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases. J Biol Chem (2011) 1.14
Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors. Chembiochem (2003) 1.13
Direct synthesis of 1,5-disubstituted-4-magnesio-1,2,3-triazoles, revisited. Org Lett (2004) 1.13
Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold. Chembiochem (2007) 1.13
One-pot copper(I)-catalyzed synthesis of 3,5-disubstituted isoxazoles. J Org Chem (2005) 1.13
A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles via a copper(I)-catalyzed three-component reaction. Org Lett (2004) 1.13
DNA-controlled assembly of a NaTl lattice structure from gold nanoparticles and protein nanoparticles. Nat Mater (2010) 1.11
A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc Natl Acad Sci U S A (2010) 1.10
Virus-glycopolymer conjugates by copper(I) catalysis of atom transfer radical polymerization and azide-alkyne cycloaddition. Chem Commun (Camb) (2005) 1.10
Copper-catalyzed reaction cascade: direct conversion of alkynes into N-sulfonylazetidin-2-imines. Angew Chem Int Ed Engl (2006) 1.08
Buckyballs meet viral nanoparticles: candidates for biomedicine. J Am Chem Soc (2009) 1.04
Degradable conjugates from oxanorbornadiene reagents. J Am Chem Soc (2012) 1.03
Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries. Bioorg Med Chem (2009) 1.02
A hierarchy of aryloxide deprotection by boron tribromide. Org Lett (2004) 1.01
Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging. J Biol Chem (2011) 1.01
Synthesis of degradable model networks via ATRP and click chemistry. J Am Chem Soc (2006) 1.00
Electrochemically protected copper(I)-catalyzed azide-alkyne cycloaddition. Chembiochem (2008) 0.99
Arylation of rhodium(II) azavinyl carbenes with boronic acids. J Am Chem Soc (2012) 0.99
RNA-directed packaging of enzymes within virus-like particles. Angew Chem Int Ed Engl (2010) 0.99
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template. J Am Chem Soc (2012) 0.99
High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon. Anal Chem (2004) 0.98
Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Curr Protoc Chem Biol (2011) 0.98
Mechanistic studies on the Cu-catalyzed three-component reactions of sulfonyl azides, 1-alkynes and amines, alcohols, or water: dichotomy via a common pathway. J Org Chem (2008) 0.98
Peptide cyclization and cyclodimerization by Cu(I)-mediated azide-alkyne cycloaddition. J Org Chem (2009) 0.97