Published in Stroke on April 21, 2005
Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res (2012) 3.02
Hypertension and cerebrovascular dysfunction. Cell Metab (2008) 2.30
Biological roles for the NOX family NADPH oxidases. J Biol Chem (2008) 1.96
Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases. Mol Cell Biol (2006) 1.80
Subcellular localization and function of alternatively spliced Noxo1 isoforms. Free Radic Biol Med (2006) 1.76
The role of oxidative stress and NADPH oxidase in cerebrovascular disease. Trends Mol Med (2008) 1.46
NOX and inflammation in the vascular adventitia. Free Radic Biol Med (2009) 1.37
Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice. Br J Pharmacol (2009) 1.36
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism. PLoS One (2011) 1.22
NADPH oxidase mediates radiation-induced oxidative stress in rat brain microvascular endothelial cells. Free Radic Biol Med (2008) 1.18
Downstream targets and intracellular compartmentalization in Nox signaling. Antioxid Redox Signal (2009) 1.16
From form to function: the role of Nox4 in the cardiovascular system. Front Physiol (2012) 1.07
Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: role of NADPH oxidase-derived ROS. Free Radic Biol Med (2007) 1.06
Lipid raft redox signaling: molecular mechanisms in health and disease. Antioxid Redox Signal (2011) 1.06
The NADPH oxidase Nox4 and aging in the heart. Aging (Albany NY) (2010) 1.04
Hydrogen peroxide is an endothelium-dependent contracting factor in rat renal artery. Br J Pharmacol (2005) 1.03
Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress. Antioxid Redox Signal (2012) 1.03
Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers. Am J Physiol Heart Circ Physiol (2009) 1.02
Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain. J Appl Physiol (1985) (2012) 0.97
Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation. Sci Signal (2015) 0.97
Nicotine worsens the severity of nephropathy in diabetic mice: implications for the progression of kidney disease in smokers. Am J Physiol Renal Physiol (2010) 0.95
Ischemia-reperfusion injury in stroke. Interv Neurol (2013) 0.94
Role of Reactive Oxygen Species in Tumor Necrosis Factor-alpha Induced Endothelial Dysfunction. Curr Hypertens Rev (2008) 0.93
Which NADPH oxidase isoform is relevant for ischemic stroke? The case for nox 2. Antioxid Redox Signal (2012) 0.91
NOX4-Dependent Hydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 Atrial Cells: Relationship to Hypertension. Front Physiol (2012) 0.89
Effects of angiotensin II on the cerebral circulation: role of oxidative stress. Front Physiol (2013) 0.88
Oxidative stress and the pathogenesis of scleroderma: the Murrell's hypothesis revisited. Semin Immunopathol (2008) 0.87
Thyroid hormone induces artery smooth muscle cell proliferation: discovery of a new TRalpha1-Nox1 pathway. J Cell Mol Med (2010) 0.85
NADPH Oxidase as a Therapeutic Target for Neuroprotection against Ischaemic Stroke: Future Perspectives. Brain Sci (2013) 0.79
Nitric oxide synthase-dependent responses of the basilar artery during acute infusion of nicotine. Nicotine Tob Res (2009) 0.79
Role of neuronal NADPH oxidase 1 in the peri-infarct regions after stroke. PLoS One (2015) 0.79
NADPH oxidase: recent evidence for its role in erectile dysfunction. Asian J Androl (2008) 0.78
NADPH oxidase in brain injury and neurodegenerative disorders. Mol Neurodegener (2017) 0.78
Generation of a conditional null allele of NADPH oxidase activator 1 (NOXA1). Genesis (2010) 0.76
Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy? Front Pharmacol (2016) 0.76
Regional Heterogeneity of Cerebral Microvessels and Brain Susceptibility to Oxidative Stress. PLoS One (2015) 0.75
CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity. Redox Biol (2016) 0.75
Microvascular NADPH oxidase in health and disease. Free Radic Biol Med (2017) 0.75
NADPH Oxidase Activity in Cerebral Arterioles Is a Key Mediator of Cerebral Small Vessel Disease-Implications for Prevention. Healthcare (Basel) (2015) 0.75
Activated microglia induce the production of reactive oxygen species and promote apoptosis of co-cultured retinal microvascular pericytes. Graefes Arch Clin Exp Ophthalmol (2017) 0.75
Regulation of Nox and Duox enzymatic activity and expression. Free Radic Biol Med (2007) 3.44
Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med (2009) 3.32
Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics. PLoS Med (2007) 3.09
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circ Res (2010) 2.65
Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase. Circulation (2004) 2.46
Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. Gastroenterology (2006) 2.33
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat Genet (2009) 2.26
Trends in the incidence, mortality, and survival rate of cardiovascular disease in a Japanese community: the Hisayama study. Stroke (2003) 2.05
Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: results from the Hisayama Study. Kidney Int (2013) 2.03
Milk and dairy consumption and risk of dementia in an elderly Japanese population: the Hisayama Study. J Am Geriatr Soc (2014) 2.02
High-sensitivity C-reactive protein and coronary heart disease in a general population of Japanese: the Hisayama study. Arterioscler Thromb Vasc Biol (2008) 1.98
Ten-year prognosis of stroke and risk factors for death in a Japanese community: the Hisayama study. Stroke (2003) 1.97
Chronic kidney disease and cardiovascular disease in a general Japanese population: the Hisayama Study. Kidney Int (2005) 1.96
Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines. Lung Cancer (2005) 1.95
Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain. Nat Med (2012) 1.90
Increased renal resistive index in atherosclerosis and diabetic nephropathy assessed by Doppler sonography. J Hypertens (2005) 1.86
Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats. Hypertension (2004) 1.85
Mesenteric phlebosclerosis: a new disease entity causing ischemic colitis. Dis Colon Rectum (2003) 1.84
Association of kidney function with coronary atherosclerosis and calcification in autopsy samples from Japanese elders: the Hisayama study. Am J Kidney Dis (2009) 1.80
Association between ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cardiovascular disease: the Hisayama Study. Atherosclerosis (2013) 1.75
Primary gastrointestinal lymphoma in Japan: a clinicopathologic analysis of 455 patients with special reference to its time trends. Cancer (2003) 1.74
Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger. J Neurosci (2007) 1.74
Age-associated prevalence and risk factors of Lewy body pathology in a general population: the Hisayama study. Acta Neuropathol (2003) 1.72
Role of aldosterone in left ventricular hypertrophy in hypertension. Am J Hypertens (2006) 1.71
Stroke in patients on maintenance hemodialysis: a 22-year single-center study. Am J Kidney Dis (2005) 1.68
NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia. Blood (2005) 1.67
Impact of metabolic syndrome on the development of cardiovascular disease in a general Japanese population: the Hisayama study. Stroke (2007) 1.67
Magnifying colonoscopy with narrow band imaging system for the diagnosis of dysplasia in ulcerative colitis: a pilot study. Gastrointest Endosc (2007) 1.66
Hyperglycemia increases risk of gastric cancer posed by Helicobacter pylori infection: a population-based cohort study. Gastroenterology (2008) 1.65
Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Gastrointest Endosc (2007) 1.62
Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. Chem Biol (2012) 1.60
Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats. Kidney Int (2008) 1.60
Impact of lower range of prehypertension on cardiovascular events in a general population: the Hisayama Study. J Hypertens (2012) 1.60
Emergency endoscopy for acute gastrointestinal bleeding: prognostic value of endoscopic hemostasis and the AIMS65 score in Japanese patients. Dig Endosc (2013) 1.59
Effect of saccharated ferric oxide and iron dextran on the metabolism of phosphorus in rats. J Lab Clin Med (2005) 1.57
A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction. Nat Genet (2007) 1.57
Prediction of coronary artery disease in patients undergoing carotid endarterectomy. J Neurosurg (2005) 1.55
Intracranial hemorrhage during dabigatran treatment. Circ J (2014) 1.54
Increased expression of gp91phox homologues of NAD(P)H oxidase in the aortic media during chronic hypertension: involvement of the renin-angiotensin system. Hypertens Res (2006) 1.53
Relationship between drinking and periodontitis: the Hisayama Study. J Periodontol (2005) 1.51
Blood pressure changes during the initial week after different subtypes of ischemic stroke. Stroke (2006) 1.50
Solitary minute metastasis from breast cancer mimicking primary intramucosal gastric signet-cell cancer. Gastrointest Endosc (2005) 1.49
Serum 1,25-dihydroxyvitamin d and the development of kidney dysfunction in a Japanese community. Circ J (2013) 1.49
Recurrent small-artery disease in hyperhomocysteinemia: widowers' stroke syndrome? Intern Med (2004) 1.47
Self-reported dietary intake of potassium, calcium, and magnesium and risk of dementia in the Japanese: the Hisayama Study. J Am Geriatr Soc (2012) 1.46
Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia. Circulation (2005) 1.46
A prospective study of dietary salt intake and gastric cancer incidence in a defined Japanese population: the Hisayama study. Int J Cancer (2006) 1.44
Regulation of myocardial growth and death by NADPH oxidase. J Mol Cell Cardiol (2011) 1.44
Nodular glomerulosclerosis in patients without any manifestation of diabetes mellitus. Nephrology (Carlton) (2007) 1.43
Intravenous calcitriol therapy in an early stage prevents parathyroid gland growth. Nephrol Dial Transplant (2008) 1.43
Angiotensin II receptor antagonist improves age-related endothelial dysfunction. J Hypertens (2002) 1.42
Dietary vitamin A intake and incidence of gastric cancer in a general Japanese population: the Hisayama Study. Gastric Cancer (2011) 1.42
Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death. Kidney Int (2003) 1.41
Brain infarction associated with antiphospholipid antibody syndrome caused by paradoxical embolism through patent foramen ovale. J Neurol (2004) 1.41
Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo. J Hypertens (2002) 1.41
Trends in the incidence and survival of intracerebral hemorrhage by its location in a Japanese community. Circ J (2013) 1.41
Development and validation of a cardiovascular risk prediction model for Japanese: the Hisayama study. Hypertens Res (2009) 1.41
Angiotensin I-converting enzyme gene polymorphism enhances the effect of hypercholesterolemia on the risk of coronary heart disease in a general Japanese population: the hisayama study. J Atheroscler Thromb (2014) 1.41
Midodrine hydrochloride and L-threo-3,4-dihydroxy-phenylserine preserve cerebral blood flow in hemodialysis patients with orthostatic hypotension. Ther Apher Dial (2007) 1.40
Constitutive NADPH-dependent electron transferase activity of the Nox4 dehydrogenase domain. Biochemistry (2010) 1.38
Liver enzymes as a predictor for incident diabetes in a Japanese population: the Hisayama study. Obesity (Silver Spring) (2007) 1.34
Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells. J Immunol (2004) 1.30
Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy. Circ Res (2012) 1.30
Dialysis-related hypotension as a cause of progressive frontal lobe atrophy in chronic hemodialysis patients: a 3-year prospective study. Nephron Clin Pract (2004) 1.30
The serum pepsinogen test as a predictor of gastric cancer: the Hisayama study. Am J Epidemiol (2006) 1.29
The dual function of hepatic SOCS3 in insulin resistance in vivo. Genes Cells (2007) 1.28
Nine-year incidence and risk factors for age-related macular degeneration in a defined Japanese population the Hisayama study. Ophthalmology (2009) 1.28
Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells. Am J Physiol Cell Physiol (2004) 1.28
Role of double-balloon endoscopy in the diagnosis of small-bowel tumors: the first Japanese multicenter study. Gastrointest Endosc (2009) 1.26
Elevated C-reactive protein is a predictor of the development of diabetes in a general Japanese population: the Hisayama Study. Diabetes Care (2005) 1.25
Impact of glucose tolerance status on development of ischemic stroke and coronary heart disease in a general Japanese population: the Hisayama study. Stroke (2009) 1.24
Association of gp91phox homolog Nox1 with anchorage-independent growth and MAP kinase-activation of transformed human keratinocytes. Oncogene (2003) 1.24
Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer. J Clin Invest (2005) 1.23
Metabolic syndrome and CKD in a general Japanese population: the Hisayama Study. Am J Kidney Dis (2006) 1.22
Comparison of human herpes virus 8 related primary effusion lymphoma with human herpes virus 8 unrelated primary effusion lymphoma-like lymphoma on the basis of HIV: report of 2 cases and review of 212 cases in the literature. Acta Haematol (2006) 1.22
NADPH oxidases in the gastrointestinal tract: a potential role of Nox1 in innate immune response and carcinogenesis. Antioxid Redox Signal (2006) 1.21