Thomas J Silhavy

Author PubWeight™ 110.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli. Cell 2005 8.22
2 Structure and function of an essential component of the outer membrane protein assembly machine. Science 2007 3.85
3 Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev 2007 3.24
4 Advances in understanding bacterial outer-membrane biogenesis. Nat Rev Microbiol 2006 3.23
5 Chemical conditionality: a genetic strategy to probe organelle assembly. Cell 2005 3.12
6 Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A 2007 3.09
7 Sensing external stress: watchdogs of the Escherichia coli cell envelope. Curr Opin Microbiol 2005 3.09
8 Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A 2006 2.87
9 YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol Microbiol 2006 2.84
10 Imp/OstA is required for cell envelope biogenesis in Escherichia coli. Mol Microbiol 2002 2.72
11 Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway. Proc Natl Acad Sci U S A 2002 2.68
12 β-Barrel membrane protein assembly by the Bam complex. Annu Rev Biochem 2011 2.55
13 Quality control in the bacterial periplasm. Biochim Biophys Acta 2004 2.29
14 Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Mol Microbiol 2008 2.27
15 Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A 2008 2.21
16 An open letter to Elias Zerhouni. Science 2005 2.19
17 Signal detection and target gene induction by the CpxRA two-component system. J Bacteriol 2003 2.16
18 Transport of lipopolysaccharide across the cell envelope: the long road of discovery. Nat Rev Microbiol 2009 2.07
19 Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli. J Bacteriol 2008 1.97
20 Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY. Science 2009 1.96
21 The Bam machine: a molecular cooper. Biochim Biophys Acta 2011 1.92
22 Probing the barrier function of the outer membrane with chemical conditionality. ACS Chem Biol 2006 1.86
23 Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A 2010 1.85
24 An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A 2009 1.81
25 Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics 2009 1.75
26 Complex spatial distribution and dynamics of an abundant Escherichia coli outer membrane protein, LamB. Mol Microbiol 2004 1.66
27 Kinetic analysis of the assembly of the outer membrane protein LamB in Escherichia coli mutants each lacking a secretion or targeting factor in a different cellular compartment. J Bacteriol 2006 1.66
28 The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A 2005 1.58
29 prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli. J Mol Biol 2007 1.57
30 Nonconsecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci U S A 2010 1.48
31 Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for β-barrel assembly in Escherichia coli. Proc Natl Acad Sci U S A 2013 1.42
32 Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A 2011 1.41
33 Escherichia coli starvation diets: essential nutrients weigh in distinctly. J Bacteriol 2005 1.40
34 Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol 2005 1.35
35 The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics. J Bacteriol 2013 1.31
36 Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria. Curr Opin Microbiol 2012 1.31
37 Secretion of LamB-LacZ by the signal recognition particle pathway of Escherichia coli. J Bacteriol 2003 1.30
38 Constitutive activation of the Escherichia coli Pho regulon upregulates rpoS translation in an Hfq-dependent fashion. J Bacteriol 2003 1.30
39 The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli. Mol Microbiol 2011 1.27
40 Continuous control in bacterial regulatory circuits. J Bacteriol 2004 1.22
41 The art and design of genetic screens: Escherichia coli. Nat Rev Genet 2003 1.19
42 Crl facilitates RNA polymerase holoenzyme formation. J Bacteriol 2006 1.17
43 A suppressor of cell death caused by the loss of sigmaE downregulates extracytoplasmic stress responses and outer membrane vesicle production in Escherichia coli. J Bacteriol 2006 1.16
44 BamE modulates the Escherichia coli beta-barrel assembly machine component BamA. J Bacteriol 2011 1.15
45 Starvation for different nutrients in Escherichia coli results in differential modulation of RpoS levels and stability. J Bacteriol 2005 1.13
46 Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate. Proc Natl Acad Sci U S A 2012 1.12
47 Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigmaS upon carbon starvation. Genes Dev 2007 1.11
48 RpoS proteolysis is regulated by a mechanism that does not require the SprE (RssB) response regulator phosphorylation site. J Bacteriol 2004 1.07
49 P pilus assembly motif necessary for activation of the CpxRA pathway by PapE in Escherichia coli. J Bacteriol 2004 1.02
50 The response regulator SprE (RssB) is required for maintaining poly(A) polymerase I-degradosome association during stationary phase. J Bacteriol 2010 1.01
51 Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. J Bacteriol 2013 0.97
52 Role for Skp in LptD assembly in Escherichia coli. J Bacteriol 2013 0.97
53 Signal sequence mutations as tools for the characterization of LamB folding intermediates. J Bacteriol 2002 0.94
54 RpoS proteolysis is controlled directly by ATP levels in Escherichia coli. Genes Dev 2012 0.92
55 LrhA regulates rpoS translation in response to the Rcs phosphorelay system in Escherichia coli. J Bacteriol 2006 0.92
56 Transcriptional occlusion caused by overlapping promoters. Proc Natl Acad Sci U S A 2014 0.89
57 The response regulator SprE (RssB) modulates polyadenylation and mRNA stability in Escherichia coli. J Bacteriol 2009 0.86
58 Predicting functionally informative mutations in Escherichia coli BamA using evolutionary covariance analysis. Genetics 2013 0.86
59 Null mutations in a Nudix gene, ygdP, implicate an alarmone response in a novel suppression of hybrid jamming. J Bacteriol 2003 0.85
60 The activity and specificity of the outer membrane protein chaperone SurA are modulated by a proline isomerase domain. MBio 2013 0.83
61 Systems biology: metabolite turns master regulator. Nature 2013 0.83
62 Sex to the rescue. Nat Methods 2008 0.75
63 Assembly of Outer Membrane β-Barrel Proteins: the Bam Complex. Ecosal Plus 2011 0.75
64 Robert a. Weisberg (1937-2011). J Bacteriol 2011 0.75
65 2012 Jack Kenney Award for Outstanding Service. J Bacteriol 2013 0.75
66 Editorial and policy changes for 2013. J Bacteriol 2012 0.75