P pilus assembly motif necessary for activation of the CpxRA pathway by PapE in Escherichia coli.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMC 421624)

Published in J Bacteriol on July 01, 2004

Authors

Yvonne M Lee1, Patricia A DiGiuseppe, Thomas J Silhavy, Scott J Hultgren

Author Affiliations

1: Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Articles citing this

Curli biogenesis and function. Annu Rev Microbiol (2006) 4.77

Characterization of the Cpx regulon in Escherichia coli strain MC4100. J Bacteriol (2008) 1.96

The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC. J Bacteriol (2005) 1.68

The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58

A tale of two pili: assembly and function of pili in bacteria. Trends Microbiol (2010) 1.47

Signal integration by the two-component signal transduction response regulator CpxR. J Bacteriol (2008) 1.40

Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol (2005) 1.35

The Cpx envelope stress response affects expression of the type IV bundle-forming pili of enteropathogenic Escherichia coli. J Bacteriol (2005) 1.31

Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli. J Bacteriol (2007) 0.97

Genetic analysis of activation of the Vibrio cholerae Cpx pathway. J Bacteriol (2009) 0.97

Identification of non-dot/icm suppressors of the Legionella pneumophila DeltadotL lethality phenotype. J Bacteriol (2006) 0.94

The role of chaperone-subunit usher domain interactions in the mechanism of bacterial pilus biogenesis revealed by ESI-MS. Mol Cell Proteomics (2012) 0.81

Dynamic interaction between the CpxA sensor kinase and the periplasmic accessory protein CpxP mediates signal recognition in E. coli. PLoS One (2014) 0.81

The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA. Protein Sci (2012) 0.78

An Overview of Two-Component Signal Transduction Systems Implicated in Extra-Intestinal Pathogenic E. coli Infections. Front Cell Infect Microbiol (2017) 0.75

Articles cited by this

Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu. J Mol Biol (1976) 33.01

Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infect Immun (1981) 14.05

Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene (1986) 13.92

X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli. Science (1999) 4.78

Localization of the receptor-binding protein adhesin at the tip of the bacterial pilus. Nature (1987) 4.72

Genes of pyelonephritogenic E. coli required for digalactoside-specific agglutination of human cells. EMBO J (1984) 4.22

The PapG protein is the alpha-D-galactopyranosyl-(1----4)-beta-D-galactopyranose-binding adhesin of uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (1987) 4.05

Crystal structure of chaperone protein PapD reveals an immunoglobulin fold. Nature (1989) 3.98

Host/vector interactions which affect the viability of recombinant phage lambda clones. Gene (1986) 3.75

Nucleotide sequence of the papA gene encoding the Pap pilus subunit of human uropathogenic Escherichia coli. J Bacteriol (1984) 3.73

Structural basis of chaperone function and pilus biogenesis. Science (1999) 3.69

P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips. Nature (1992) 3.47

Pilus and nonpilus bacterial adhesins: assembly and function in cell recognition. Cell (1993) 3.39

The Gal(alpha 1-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract. Proc Natl Acad Sci U S A (1994) 3.02

Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses. Proc Natl Acad Sci U S A (2000) 2.98

Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. Genes Dev (1997) 2.96

Outer-membrane PapC molecular usher discriminately recognizes periplasmic chaperone-pilus subunit complexes. Proc Natl Acad Sci U S A (1993) 2.91

The sigma(E) and the Cpx signal transduction systems control the synthesis of periplasmic protein-folding enzymes in Escherichia coli. Genes Dev (1997) 2.84

Transduction of envelope stress in Escherichia coli by the Cpx two-component system. J Bacteriol (1997) 2.56

Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54

Overproduction of NlpE, a new outer membrane lipoprotein, suppresses the toxicity of periplasmic LacZ by activation of the Cpx signal transduction pathway. J Bacteriol (1995) 2.52

The chaperone-assisted membrane release and folding pathway is sensed by two signal transduction systems. EMBO J (1997) 2.52

Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1----4Gal-containing glycosphingolipids. J Biol Chem (1985) 2.48

Biogenesis of E. coli Pap pili: papH, a minor pilin subunit involved in cell anchoring and length modulation. Cell (1987) 2.44

CpxP, a stress-combative member of the Cpx regulon. J Bacteriol (1998) 2.42

The PapG adhesin of uropathogenic Escherichia coli contains separate regions for receptor binding and for the incorporation into the pilus. Proc Natl Acad Sci U S A (1989) 2.36

Host-specificity of uropathogenic Escherichia coli depends on differences in binding specificity to Gal alpha 1-4Gal-containing isoreceptors. EMBO J (1990) 2.31

Structural basis of pilus subunit recognition by the PapD chaperone. Science (1993) 2.30

The Cpx envelope stress response is controlled by amplification and feedback inhibition. J Bacteriol (1999) 2.26

Immunoglobulin-like PapD chaperone caps and uncaps interactive surfaces of nascently translocated pilus subunits. Proc Natl Acad Sci U S A (1991) 2.25

The sigmaE and Cpx regulatory pathways: overlapping but distinct envelope stress responses. Curr Opin Microbiol (1999) 2.20

PapD, a periplasmic transport protein in P-pilus biogenesis. J Bacteriol (1989) 2.19

Signal detection and target gene induction by the CpxRA two-component system. J Bacteriol (2003) 2.16

Initiation of assembly and association of the structural elements of a bacterial pilus depend on two specialized tip proteins. EMBO J (1993) 2.12

Structural polymorphism of bacterial adhesion pili. Nature (1995) 2.12

Interactive surface in the PapD chaperone cleft is conserved in pilus chaperone superfamily and essential in subunit recognition and assembly. EMBO J (1992) 2.12

Genome-wide profiling of promoter recognition by the two-component response regulator CpxR-P in Escherichia coli. J Biol Chem (2002) 2.09

Cpx signaling pathway monitors biogenesis and affects assembly and expression of P pili. EMBO J (2001) 2.08

The PapC usher forms an oligomeric channel: implications for pilus biogenesis across the outer membrane. Proc Natl Acad Sci U S A (1998) 2.01

A third envelope stress signal transduction pathway in Escherichia coli. Mol Microbiol (2002) 1.99

PapD-like chaperones provide the missing information for folding of pilin proteins. Proc Natl Acad Sci U S A (2000) 1.98

Adhesion and entry of uropathogenic Escherichia coli. Cell Microbiol (2002) 1.97

Molecular basis of two subfamilies of immunoglobulin-like chaperones. EMBO J (1996) 1.88

The chaperone/usher pathway: a major terminal branch of the general secretory pathway. Curr Opin Microbiol (1998) 1.86

Conserved immunoglobulin-like features in a family of periplasmic pilus chaperones in bacteria. EMBO J (1992) 1.79

Ramifications of kinetic partitioning on usher-mediated pilus biogenesis. EMBO J (1998) 1.76

Mutational activation of the Cpx signal transduction pathway of Escherichia coli suppresses the toxicity conferred by certain envelope-associated stresses. Mol Microbiol (1995) 1.70

Involvement of cpxA, a sensor of a two-component regulatory system, in the pH-dependent regulation of expression of Shigella sonnei virF gene. J Bacteriol (1995) 1.68

Helical structure of P pili from Escherichia coli. Evidence from X-ray fiber diffraction and scanning transmission electron microscopy. J Mol Biol (1992) 1.63

The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways. Genes Dev (1997) 1.57

The Cpx two-component signal transduction pathway is activated in Escherichia coli mutant strains lacking phosphatidylethanolamine. J Bacteriol (1997) 1.50

Tethering of CpxP to the inner membrane prevents spheroplast induction of the cpx envelope stress response. Mol Microbiol (2000) 1.42

Assembly of complex organelles: pilus biogenesis in gram-negative bacteria as a model system. Methods (2000) 1.41

Snapshots of usher-mediated protein secretion and ordered pilus assembly. Proc Natl Acad Sci U S A (2000) 1.40

Periplasmic chaperone recognition motif of subunits mediates quaternary interactions in the pilus. EMBO J (1998) 1.40

Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis. J Bacteriol (2002) 1.24

Stable fiber-forming and nonfiber-forming chaperone-subunit complexes in pilus biogenesis. J Biol Chem (1994) 1.21

A PCR-based strategy for extensive mutagenesis of a target DNA sequence. Biotechniques (1993) 1.21

Chaperone-subunit-usher interactions required for donor strand exchange during bacterial pilus assembly. J Bacteriol (2003) 1.04

Structural basis of chaperone self-capping in P pilus biogenesis. Proc Natl Acad Sci U S A (1999) 0.95

Probing conserved surfaces on PapD. Mol Microbiol (1999) 0.90

Articles by these authors

Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli. Cell (2005) 8.22

Intracellular bacterial biofilm-like pods in urinary tract infections. Science (2003) 7.10

Role of Escherichia coli curli operons in directing amyloid fiber formation. Science (2002) 5.58

Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. Proc Natl Acad Sci U S A (2006) 5.13

Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12

Structure and function of an essential component of the outer membrane protein assembly machine. Science (2007) 3.85

The biology and future prospects of antivirulence therapies. Nat Rev Microbiol (2008) 3.83

Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med (2007) 3.54

Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract. Proc Natl Acad Sci U S A (2006) 3.36

Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol (2002) 3.26

Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev (2007) 3.24

Advances in understanding bacterial outer-membrane biogenesis. Nat Rev Microbiol (2006) 3.23

Chemical conditionality: a genetic strategy to probe organelle assembly. Cell (2005) 3.12

Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A (2007) 3.09

Sensing external stress: watchdogs of the Escherichia coli cell envelope. Curr Opin Microbiol (2005) 3.09

Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2006) 2.87

YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol Microbiol (2006) 2.84

Imp/OstA is required for cell envelope biogenesis in Escherichia coli. Mol Microbiol (2002) 2.72

Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69

Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway. Proc Natl Acad Sci U S A (2002) 2.68

β-Barrel membrane protein assembly by the Bam complex. Annu Rev Biochem (2011) 2.55

Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52

Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili. Cell Microbiol (2007) 2.48

Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli. J Biol Chem (2001) 2.34

Quality control in the bacterial periplasm. Biochim Biophys Acta (2004) 2.29

Morphological plasticity as a bacterial survival strategy. Nat Rev Microbiol (2008) 2.28

Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Mol Microbiol (2008) 2.27

Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2008) 2.21

Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect Immun (2002) 2.20

An open letter to Elias Zerhouni. Science (2005) 2.19

Structural biology of the chaperone-usher pathway of pilus biogenesis. Nat Rev Microbiol (2009) 2.19

Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17

Signal detection and target gene induction by the CpxRA two-component system. J Bacteriol (2003) 2.16

Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med (2011) 2.16

Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15

A murine model of urinary tract infection. Nat Protoc (2009) 2.15

Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein. Mol Microbiol (2006) 2.14

Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation. Infect Immun (2006) 2.11

Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization. Infect Immun (2005) 2.10

Transport of lipopolysaccharide across the cell envelope: the long road of discovery. Nat Rev Microbiol (2009) 2.07

Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2003) 2.02

Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli. J Bacteriol (2008) 1.97

Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY. Science (2009) 1.96

Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. Microbes Infect (2010) 1.95

The Bam machine: a molecular cooper. Biochim Biophys Acta (2011) 1.92

Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Mol Microbiol (2005) 1.90

Fiber assembly by the chaperone-usher pathway. Biochim Biophys Acta (2004) 1.89

Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection. Sci Transl Med (2013) 1.88

Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathog (2010) 1.88

Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A (2006) 1.87

Probing the barrier function of the outer membrane with chemical conditionality. ACS Chem Biol (2006) 1.86

Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A (2010) 1.85

Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli. PLoS Pathog (2009) 1.83

Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. J Urol (2004) 1.82

An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A (2009) 1.81

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Mol Cell (2006) 1.81

A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. J Infect Dis (2013) 1.76

Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics (2009) 1.75

Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67

Complex spatial distribution and dynamics of an abundant Escherichia coli outer membrane protein, LamB. Mol Microbiol (2004) 1.66

Kinetic analysis of the assembly of the outer membrane protein LamB in Escherichia coli mutants each lacking a secretion or targeting factor in a different cellular compartment. J Bacteriol (2006) 1.66

Functional genomic studies of uropathogenic Escherichia coli and host urothelial cells when intracellular bacterial communities are assembled. J Biol Chem (2007) 1.64

Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection. Infect Immun (2012) 1.64

Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis. Trends Microbiol (2004) 1.62

The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58

prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli. J Mol Biol (2007) 1.57

Maturation of intracellular Escherichia coli communities requires SurA. Infect Immun (2006) 1.56

Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding. Proc Natl Acad Sci U S A (2009) 1.56

Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli. Infect Immun (2005) 1.55

Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55

Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection. Cell Host Microbe (2009) 1.51

Nonconsecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci U S A (2010) 1.48

Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific. J Infect Dis (2012) 1.48

QseC-mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenic Escherichia coli. Mol Microbiol (2009) 1.47

A tale of two pili: assembly and function of pili in bacteria. Trends Microbiol (2010) 1.47

Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF. Proc Natl Acad Sci U S A (2009) 1.43

Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for β-barrel assembly in Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.42

Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.41

Escherichia coli starvation diets: essential nutrients weigh in distinctly. J Bacteriol (2005) 1.40

Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J Med Chem (2010) 1.40

The Legionella pneumophila PilT homologue DotB exhibits ATPase activity that is critical for intracellular growth. J Bacteriol (2004) 1.39

Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. Cold Spring Harb Perspect Med (2013) 1.38

CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli. Infect Immun (2003) 1.38

LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis. Mol Microbiol (2007) 1.37

Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression. Infect Immun (2008) 1.36

Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection. Infect Immun (2011) 1.36

Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol (2005) 1.35

CsgE is a curli secretion specificity factor that prevents amyloid fibre aggregation. Mol Microbiol (2011) 1.34

Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli. Cell Microbiol (2002) 1.34

The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics. J Bacteriol (2013) 1.31

Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria. Curr Opin Microbiol (2012) 1.31

Secretion of LamB-LacZ by the signal recognition particle pathway of Escherichia coli. J Bacteriol (2003) 1.30

Constitutive activation of the Escherichia coli Pho regulon upregulates rpoS translation in an Hfq-dependent fashion. J Bacteriol (2003) 1.30

The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli. Mol Microbiol (2011) 1.27

Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice. Infect Immun (2005) 1.26

A central metabolic circuit controlled by QseC in pathogenic Escherichia coli. Mol Microbiol (2011) 1.26

Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis. J Bacteriol (2002) 1.24