Published in Cell on April 22, 2005
Reconstitution of outer membrane protein assembly from purified components. Science (2010) 3.30
Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev (2007) 3.24
Assembly factor Omp85 recognizes its outer membrane protein substrates by a species-specific C-terminal motif. PLoS Biol (2006) 3.12
Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A (2007) 3.09
Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2006) 2.87
The bacterial actin MreB rotates, and rotation depends on cell-wall assembly. Proc Natl Acad Sci U S A (2011) 2.61
Membrane protein architects: the role of the BAM complex in outer membrane protein assembly. Nat Rev Microbiol (2009) 2.52
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2008) 2.21
Cell shape and cell-wall organization in Gram-negative bacteria. Proc Natl Acad Sci U S A (2008) 2.13
Crystal structure of YaeT: conformational flexibility and substrate recognition. Structure (2008) 1.93
The Bam machine: a molecular cooper. Biochim Biophys Acta (2011) 1.92
Characterization of six lipoproteins in the sigmaE regulon. J Bacteriol (2005) 1.91
Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A (2010) 1.85
An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A (2009) 1.81
Interaction of an autotransporter passenger domain with BamA during its translocation across the bacterial outer membrane. Proc Natl Acad Sci U S A (2009) 1.79
Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics (2009) 1.75
Kinetic analysis of the assembly of the outer membrane protein LamB in Escherichia coli mutants each lacking a secretion or targeting factor in a different cellular compartment. J Bacteriol (2006) 1.66
Hopanoids play a role in membrane integrity and pH homeostasis in Rhodopseudomonas palustris TIE-1. J Bacteriol (2009) 1.61
Membrane protein insertion: mixing eukaryotic and prokaryotic concepts. EMBO Rep (2005) 1.58
Analysis of YfgL and YaeT interactions through bioinformatics, mutagenesis, and biochemistry. J Bacteriol (2007) 1.55
Bacterial outer membrane secretin PulD assembles and inserts into the inner membrane in the absence of its pilotin. EMBO J (2006) 1.52
Differential effects of yfgL mutation on Escherichia coli outer membrane proteins and lipopolysaccharide. J Bacteriol (2006) 1.51
Ab initio genotype-phenotype association reveals intrinsic modularity in genetic networks. Mol Syst Biol (2006) 1.49
The crystal structure of BamB suggests interactions with BamA and its role within the BAM complex. J Mol Biol (2011) 1.48
A synthetic lethal approach for compound and target identification in Staphylococcus aureus. Nat Chem Biol (2015) 1.47
Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons. Nature (2015) 1.46
Structure and function of BamE within the outer membrane and the β-barrel assembly machine. EMBO Rep (2011) 1.45
Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for β-barrel assembly in Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.42
Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.41
Protein secretion and outer membrane assembly in Alphaproteobacteria. FEMS Microbiol Rev (2008) 1.37
The cavity-chaperone Skp protects its substrate from aggregation but allows independent folding of substrate domains. Proc Natl Acad Sci U S A (2009) 1.29
Structural basis for outer membrane lipopolysaccharide insertion. Nature (2014) 1.28
Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules. Proc Natl Acad Sci U S A (2013) 1.24
Structural biology of membrane-intrinsic beta-barrel enzymes: sentinels of the bacterial outer membrane. Biochim Biophys Acta (2007) 1.22
The peripheral membrane subunits of the SAM complex function codependently in mitochondrial outer membrane biogenesis. Mol Biol Cell (2007) 1.20
The Bacillus subtilis cannibalism toxin SDP collapses the proton motive force and induces autolysis. Mol Microbiol (2012) 1.17
BamE modulates the Escherichia coli beta-barrel assembly machine component BamA. J Bacteriol (2011) 1.15
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity. Nat Prod Rep (2010) 1.15
Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals. J Am Chem Soc (2009) 1.12
Hopanoid production is required for low-pH tolerance, antimicrobial resistance, and motility in Burkholderia cenocepacia. J Bacteriol (2011) 1.10
The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains. J Bacteriol (2013) 1.08
Dissecting the Escherichia coli periplasmic chaperone network using differential proteomics. Proteomics (2012) 1.07
Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol (2016) 1.05
Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways. PLoS Genet (2011) 1.05
On the essentiality of lipopolysaccharide to Gram-negative bacteria. Curr Opin Microbiol (2013) 1.04
The protein-disulfide isomerase DsbC cooperates with SurA and DsbA in the assembly of the essential β-barrel protein LptD. J Biol Chem (2010) 1.03
The YfgL lipoprotein is essential for type III secretion system expression and virulence of Salmonella enterica Serovar Enteritidis. Infect Immun (2006) 1.02
Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Proc Natl Acad Sci U S A (2014) 0.98
Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. J Bacteriol (2013) 0.97
Role for Skp in LptD assembly in Escherichia coli. J Bacteriol (2013) 0.97
The periplasmic folding of a cysteineless autotransporter passenger domain interferes with its outer membrane translocation. J Bacteriol (2006) 0.97
Analysis of novel soluble chromate and uranyl reductases and generation of an improved enzyme by directed evolution. Appl Environ Microbiol (2006) 0.97
LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface. Proc Natl Acad Sci U S A (2014) 0.96
bam Lipoproteins Assemble BamA in vitro. Biochemistry (2013) 0.95
Monocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteases. ACS Chem Biol (2011) 0.95
Lipopolysaccharide transport to the cell surface: periplasmic transport and assembly into the outer membrane. Philos Trans R Soc Lond B Biol Sci (2015) 0.94
Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway. Proc Natl Acad Sci U S A (2016) 0.94
Crystal structure of BamB bound to a periplasmic domain fragment of BamA, the central component of the β-barrel assembly machine. J Biol Chem (2014) 0.93
Protease homolog BepA (YfgC) promotes assembly and degradation of β-barrel membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A (2013) 0.90
Outer membrane antigens of the uropathogen Proteus mirabilis recognized by the humoral response during experimental murine urinary tract infection. Infect Immun (2008) 0.90
Factors affecting the folding of Pseudomonas aeruginosa OprF porin into the one-domain open conformer. MBio (2010) 0.90
Outer membrane biogenesis in Escherichia coli, Neisseria meningitidis, and Helicobacter pylori: paradigm deviations in H. pylori. Front Cell Infect Microbiol (2012) 0.89
The BAM complex subunit BamE (SmpA) is required for membrane integrity, stalk growth and normal levels of outer membrane {beta}-barrel proteins in Caulobacter crescentus. Microbiology (2009) 0.89
Validation of inhibitors of an ABC transporter required to transport lipopolysaccharide to the cell surface in Escherichia coli. Bioorg Med Chem (2013) 0.88
Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol Cell (2016) 0.87
Emerging roles for anionic non-bilayer phospholipids in fortifying the outer membrane permeability barrier. J Bacteriol (2014) 0.86
Fluorescein analogues inhibit SecA ATPase: the first sub-micromolar inhibitor of bacterial protein translocation. ChemMedChem (2012) 0.86
Predicting functionally informative mutations in Escherichia coli BamA using evolutionary covariance analysis. Genetics (2013) 0.86
The first low microM SecA inhibitors. Bioorg Med Chem (2010) 0.86
Accumulation of phosphatidic acid increases vancomycin resistance in Escherichia coli. J Bacteriol (2014) 0.85
Crystal structure of BamB from Pseudomonas aeruginosa and functional evaluation of its conserved structural features. PLoS One (2012) 0.85
Components of the E. coli envelope are affected by and can react to protein over-production in the cytoplasm. Microb Cell Fact (2009) 0.85
Characterization of a stalled complex on the β-barrel assembly machine. Proc Natl Acad Sci U S A (2016) 0.83
Protein interactions in genome maintenance as novel antibacterial targets. PLoS One (2013) 0.83
The activity and specificity of the outer membrane protein chaperone SurA are modulated by a proline isomerase domain. MBio (2013) 0.83
Application of a novel microtitre plate-based assay for the discovery of new inhibitors of DNA gyrase and DNA topoisomerase VI. PLoS One (2013) 0.83
Fitting the Pieces of the β-Barrel Assembly Machinery Complex. Biochemistry (2015) 0.83
Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens. ACS Med Chem Lett (2016) 0.83
The Structure of a BamA-BamD Fusion Illuminates the Architecture of the β-Barrel Assembly Machine Core. Structure (2015) 0.82
Mutant Alleles of lptD Increase the Permeability of Pseudomonas aeruginosa and Define Determinants of Intrinsic Resistance to Antibiotics. Antimicrob Agents Chemother (2015) 0.82
Loss of membrane-bound lytic transglycosylases increases outer membrane permeability and β-lactam sensitivity in Pseudomonas aeruginosa. Microbiologyopen (2015) 0.82
A head-to-head comparison of eneamide and epoxyamide inhibitors of glucosamine-6-phosphate synthase from the dapdiamide biosynthetic pathway. Biochemistry (2011) 0.81
BB0324 and BB0028 are constituents of the Borrelia burgdorferi β-barrel assembly machine (BAM) complex. BMC Microbiol (2012) 0.81
Fragments of the bacterial toxin microcin B17 as gyrase poisons. PLoS One (2013) 0.81
Insights into the function of YciM, a heat shock membrane protein required to maintain envelope integrity in Escherichia coli. J Bacteriol (2013) 0.81
A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane. Elife (2016) 0.81
SecA: a potential antimicrobial target. Future Med Chem (2015) 0.79
Deciphering the roles of BamB and its interaction with BamA in outer membrane biogenesis, T3SS expression and virulence in Salmonella. PLoS One (2012) 0.79
SurA is involved in the targeting to the outer membrane of a Tat signal sequence-anchored protein. J Bacteriol (2012) 0.78
Constitutive expression of the maltoporin LamB in the absence of OmpR damages the cell envelope. J Bacteriol (2010) 0.78
Lichenicidin biosynthesis in Escherichia coli: licFGEHI immunity genes are not essential for lantibiotic production or self-protection. Appl Environ Microbiol (2011) 0.78
A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface. Elife (2014) 0.78
Inhibition of virulence-promoting disulfide bond formation enzyme DsbB is blocked by mutating residues in two distinct regions. J Biol Chem (2017) 0.78
Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop. Proc Natl Acad Sci U S A (2017) 0.78
Assembly of the β-Barrel Outer Membrane Proteins in Gram-Negative Bacteria, Mitochondria, and Chloroplasts. ISRN Mol Biol (2012) 0.77
SimC7 Is a Novel NAD(P)H-Dependent Ketoreductase Essential for the Antibiotic Activity of the DNA Gyrase Inhibitor Simocyclinone. J Mol Biol (2015) 0.77
Density gradient enrichment of Escherichia coli conditional msbA mutants. Appl Environ Microbiol (2007) 0.77
Design, Synthesis and Evaluation of Triazole-Pyrimidine Analogues as SecA Inhibitors. ChemMedChem (2015) 0.76
Characterization of the β-barrel assembly machine accessory lipoproteins from Borrelia burgdorferi. BMC Microbiol (2015) 0.76
Competition between VanU(G) repressor and VanR(G) activator leads to rheostatic control of vanG vancomycin resistance operon expression. PLoS Genet (2015) 0.76
Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli. Cell (2005) 8.22
The bacterial cell envelope. Cold Spring Harb Perspect Biol (2010) 5.14
Structure and function of an essential component of the outer membrane protein assembly machine. Science (2007) 3.85
Reconstitution of outer membrane protein assembly from purified components. Science (2010) 3.30
Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev (2007) 3.24
Advances in understanding bacterial outer-membrane biogenesis. Nat Rev Microbiol (2006) 3.23
Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A (2007) 3.09
Sensing external stress: watchdogs of the Escherichia coli cell envelope. Curr Opin Microbiol (2005) 3.09
Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2006) 2.87
YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol Microbiol (2006) 2.84
Imp/OstA is required for cell envelope biogenesis in Escherichia coli. Mol Microbiol (2002) 2.72
Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway. Proc Natl Acad Sci U S A (2002) 2.68
β-Barrel membrane protein assembly by the Bam complex. Annu Rev Biochem (2011) 2.55
Quality control in the bacterial periplasm. Biochim Biophys Acta (2004) 2.29
Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Mol Microbiol (2008) 2.27
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2008) 2.21
An open letter to Elias Zerhouni. Science (2005) 2.19
Signal detection and target gene induction by the CpxRA two-component system. J Bacteriol (2003) 2.16
Transport of lipopolysaccharide across the cell envelope: the long road of discovery. Nat Rev Microbiol (2009) 2.07
Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases. Proc Natl Acad Sci U S A (2003) 2.02
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli. J Bacteriol (2008) 1.97
Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate. Proc Natl Acad Sci U S A (2003) 1.96
Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY. Science (2009) 1.96
The Bam machine: a molecular cooper. Biochim Biophys Acta (2011) 1.92
Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli. Proc Natl Acad Sci U S A (2012) 1.91
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chem Biol (2002) 1.90
Probing the barrier function of the outer membrane with chemical conditionality. ACS Chem Biol (2006) 1.86
Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A (2010) 1.85
An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A (2009) 1.81
Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics (2009) 1.75
Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis. Proc Natl Acad Sci U S A (2007) 1.68
The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel. Proc Natl Acad Sci U S A (2011) 1.68
Complex spatial distribution and dynamics of an abundant Escherichia coli outer membrane protein, LamB. Mol Microbiol (2004) 1.66
Kinetic analysis of the assembly of the outer membrane protein LamB in Escherichia coli mutants each lacking a secretion or targeting factor in a different cellular compartment. J Bacteriol (2006) 1.66
The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58
prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli. J Mol Biol (2007) 1.57
Proteins required for lipopolysaccharide assembly in Escherichia coli form a transenvelope complex. Biochemistry (2010) 1.54
Nonconsecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci U S A (2010) 1.48
Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for β-barrel assembly in Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.42
Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.41
Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. J Bacteriol (2005) 1.41
Escherichia coli starvation diets: essential nutrients weigh in distinctly. J Bacteriol (2005) 1.40
Distinct single-cell morphological dynamics under beta-lactam antibiotics. Mol Cell (2012) 1.39
Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli. Science (2012) 1.37
Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. J Am Chem Soc (2011) 1.37
Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. J Biol Chem (2007) 1.36
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol (2005) 1.35
Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export. Biochemistry (2012) 1.35
The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics. J Bacteriol (2013) 1.31
Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria. Curr Opin Microbiol (2012) 1.31
Secretion of LamB-LacZ by the signal recognition particle pathway of Escherichia coli. J Bacteriol (2003) 1.30
Constitutive activation of the Escherichia coli Pho regulon upregulates rpoS translation in an Hfq-dependent fashion. J Bacteriol (2003) 1.30
Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery. Proc Natl Acad Sci U S A (2009) 1.29
The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli. Mol Microbiol (2011) 1.27
Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. J Am Chem Soc (2005) 1.23
Continuous control in bacterial regulatory circuits. J Bacteriol (2004) 1.22
The art and design of genetic screens: Escherichia coli. Nat Rev Genet (2003) 1.19
Complete characterization of the seventeen step moenomycin biosynthetic pathway. Biochemistry (2009) 1.19
Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design. ACS Chem Biol (2008) 1.19
Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II. J Am Chem Soc (2013) 1.18
AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A. Chem Biol (2005) 1.18
The reconstituted Escherichia coli Bam complex catalyzes multiple rounds of β-barrel assembly. Biochemistry (2011) 1.17
Crl facilitates RNA polymerase holoenzyme formation. J Bacteriol (2006) 1.17
A suppressor of cell death caused by the loss of sigmaE downregulates extracytoplasmic stress responses and outer membrane vesicle production in Escherichia coli. J Bacteriol (2006) 1.16
BamE modulates the Escherichia coli beta-barrel assembly machine component BamA. J Bacteriol (2011) 1.15
The structural basis for induction of VanB resistance. J Am Chem Soc (2002) 1.15
D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. J Bacteriol (2013) 1.15
In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. J Am Chem Soc (2005) 1.13
Starvation for different nutrients in Escherichia coli results in differential modulation of RpoS levels and stability. J Bacteriol (2005) 1.13
Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate. Proc Natl Acad Sci U S A (2012) 1.12
Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export. Science (2012) 1.11
Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigmaS upon carbon starvation. Genes Dev (2007) 1.11
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. J Am Chem Soc (2010) 1.11
Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. J Am Chem Soc (2013) 1.10
Isolated peptidoglycan glycosyltransferases from different organisms produce different glycan chain lengths. J Am Chem Soc (2008) 1.09
The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains. J Bacteriol (2013) 1.08
RpoS proteolysis is regulated by a mechanism that does not require the SprE (RssB) response regulator phosphorylation site. J Bacteriol (2004) 1.07
A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases. J Am Chem Soc (2005) 1.05
Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn. Cancer Immunol Immunother (2004) 1.05
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. J Am Chem Soc (2011) 1.04