Published in Cell on April 22, 2005
The bacterial cell envelope. Cold Spring Harb Perspect Biol (2010) 5.14
Conserved and variable functions of the sigmaE stress response in related genomes. PLoS Biol (2006) 4.46
Reconstitution of outer membrane protein assembly from purified components. Science (2010) 3.30
Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev (2007) 3.24
Assembly factor Omp85 recognizes its outer membrane protein substrates by a species-specific C-terminal motif. PLoS Biol (2006) 3.12
Chemical conditionality: a genetic strategy to probe organelle assembly. Cell (2005) 3.12
Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A (2007) 3.09
Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2006) 2.87
The bacterial actin MreB rotates, and rotation depends on cell-wall assembly. Proc Natl Acad Sci U S A (2011) 2.61
Membrane protein architects: the role of the BAM complex in outer membrane protein assembly. Nat Rev Microbiol (2009) 2.52
Structural insight into the biogenesis of β-barrel membrane proteins. Nature (2013) 2.46
Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Mol Microbiol (2008) 2.27
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2008) 2.21
Cell shape and cell-wall organization in Gram-negative bacteria. Proc Natl Acad Sci U S A (2008) 2.13
AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin. Structure (2010) 1.97
Crystal structure of YaeT: conformational flexibility and substrate recognition. Structure (2008) 1.93
The Bam machine: a molecular cooper. Biochim Biophys Acta (2011) 1.92
Structure and flexibility of the complete periplasmic domain of BamA: the protein insertion machine of the outer membrane. Structure (2010) 1.92
Characterization of six lipoproteins in the sigmaE regulon. J Bacteriol (2005) 1.91
Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A (2010) 1.85
An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A (2009) 1.81
Interaction of an autotransporter passenger domain with BamA during its translocation across the bacterial outer membrane. Proc Natl Acad Sci U S A (2009) 1.79
Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics (2009) 1.75
Secretion by numbers: Protein traffic in prokaryotes. Mol Microbiol (2006) 1.75
The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel. Proc Natl Acad Sci U S A (2011) 1.68
Kinetic analysis of the assembly of the outer membrane protein LamB in Escherichia coli mutants each lacking a secretion or targeting factor in a different cellular compartment. J Bacteriol (2006) 1.66
Biogenesis of beta-barrel membrane proteins in bacteria and eukaryotes: evolutionary conservation and divergence. Cell Mol Life Sci (2009) 1.62
Membrane protein insertion: mixing eukaryotic and prokaryotic concepts. EMBO Rep (2005) 1.58
Analysis of YfgL and YaeT interactions through bioinformatics, mutagenesis, and biochemistry. J Bacteriol (2007) 1.55
Proteins required for lipopolysaccharide assembly in Escherichia coli form a transenvelope complex. Biochemistry (2010) 1.54
Bacterial outer membrane secretin PulD assembles and inserts into the inner membrane in the absence of its pilotin. EMBO J (2006) 1.52
Protein secretion and membrane insertion systems in gram-negative bacteria. J Membr Biol (2007) 1.51
Differential effects of yfgL mutation on Escherichia coli outer membrane proteins and lipopolysaccharide. J Bacteriol (2006) 1.51
Antibiotic stress, genetic response and altered permeability of E. coli. PLoS One (2007) 1.50
Ab initio genotype-phenotype association reveals intrinsic modularity in genetic networks. Mol Syst Biol (2006) 1.49
Nonconsecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci U S A (2010) 1.48
The crystal structure of BamB suggests interactions with BamA and its role within the BAM complex. J Mol Biol (2011) 1.48
A modular BAM complex in the outer membrane of the alpha-proteobacterium Caulobacter crescentus. PLoS One (2010) 1.46
Crystal structure of BamD: an essential component of the β-Barrel assembly machinery of gram-negative bacteria. J Mol Biol (2011) 1.45
Requirement for YaeT in the outer membrane assembly of autotransporter proteins. J Bacteriol (2007) 1.45
Structure and function of BamE within the outer membrane and the β-barrel assembly machine. EMBO Rep (2011) 1.45
Cytotoxin ClyA from Escherichia coli assembles to a 13-meric pore independent of its redox-state. EMBO J (2006) 1.43
Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for β-barrel assembly in Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.42
Lateral opening and exit pore formation are required for BamA function. Structure (2014) 1.42
Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.41
Signals in bacterial beta-barrel proteins are functional in eukaryotic cells for targeting to and assembly in mitochondria. Proc Natl Acad Sci U S A (2009) 1.40
Functioning of outer membrane protein assembly factor Omp85 requires a single POTRA domain. EMBO Rep (2007) 1.39
Dissection of β-barrel outer membrane protein assembly pathways through characterizing BamA POTRA 1 mutants of Escherichia coli. Mol Microbiol (2010) 1.38
Protein secretion and outer membrane assembly in Alphaproteobacteria. FEMS Microbiol Rev (2008) 1.37
Bacterial contact-dependent growth inhibition. Trends Microbiol (2013) 1.36
The N-terminal domain of Tob55 has a receptor-like function in the biogenesis of mitochondrial beta-barrel proteins. J Cell Biol (2006) 1.35
Outer membrane β-barrel protein folding is physically controlled by periplasmic lipid head groups and BamA. Proc Natl Acad Sci U S A (2014) 1.34
The LptA protein of Escherichia coli is a periplasmic lipid A-binding protein involved in the lipopolysaccharide export pathway. J Biol Chem (2008) 1.34
Sequential and spatially restricted interactions of assembly factors with an autotransporter beta domain. Proc Natl Acad Sci U S A (2011) 1.32
Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria. Curr Opin Microbiol (2012) 1.31
The beta-barrel outer membrane protein assembly complex of Neisseria meningitidis. J Bacteriol (2009) 1.30
The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli. Mol Microbiol (2011) 1.27
Cooperation of translocase complexes in mitochondrial protein import. J Cell Biol (2007) 1.26
Structural biology of membrane-intrinsic beta-barrel enzymes: sentinels of the bacterial outer membrane. Biochim Biophys Acta (2007) 1.22
Short-tailed stx phages exploit the conserved YaeT protein to disseminate Shiga toxin genes among enterobacteria. J Bacteriol (2007) 1.21
MicL, a new σE-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein. Genes Dev (2014) 1.21
The peripheral membrane subunits of the SAM complex function codependently in mitochondrial outer membrane biogenesis. Mol Biol Cell (2007) 1.20
Secretion of a bacterial virulence factor is driven by the folding of a C-terminal segment. Proc Natl Acad Sci U S A (2010) 1.19
Systems-level antimicrobial drug and drug synergy discovery. Nat Chem Biol (2013) 1.19
Promoter strength properties of the complete sigma E regulon of Escherichia coli and Salmonella enterica. J Bacteriol (2009) 1.19
The reconstituted Escherichia coli Bam complex catalyzes multiple rounds of β-barrel assembly. Biochemistry (2011) 1.17
Direct visualization of red fluorescent lipoproteins indicates conservation of the membrane sorting rules in the family Enterobacteriaceae. J Bacteriol (2006) 1.17
The role of Borrelia burgdorferi outer surface proteins. FEMS Immunol Med Microbiol (2012) 1.16
MzrA: a novel modulator of the EnvZ/OmpR two-component regulon. Mol Microbiol (2009) 1.16
BamE modulates the Escherichia coli beta-barrel assembly machine component BamA. J Bacteriol (2011) 1.15
Structure of the BamC two-domain protein obtained by Rosetta with a limited NMR data set. J Mol Biol (2011) 1.15
Membrane protein thermodynamic stability may serve as the energy sink for sorting in the periplasm. Proc Natl Acad Sci U S A (2013) 1.14
Role of periplasmic chaperones and BamA (YaeT/Omp85) in folding and secretion of intimin from enteropathogenic Escherichia coli strains. J Bacteriol (2009) 1.14
Delivery of CdiA nuclease toxins into target cells during contact-dependent growth inhibition. PLoS One (2013) 1.13
Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate. Proc Natl Acad Sci U S A (2012) 1.12
The Omp85-related chloroplast outer envelope protein OEP80 is essential for viability in Arabidopsis. Plant Physiol (2008) 1.12
Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export. Science (2012) 1.11
The bacterial outer membrane β-barrel assembly machinery. Protein Sci (2012) 1.10
Novel mechanism of Escherichia coli porin regulation. J Bacteriol (2006) 1.08
Dissecting the Escherichia coli periplasmic chaperone network using differential proteomics. Proteomics (2012) 1.07
Disulfide bond formation in the bacterial periplasm: major achievements and challenges ahead. Antioxid Redox Signal (2012) 1.07
Omp85 from the thermophilic cyanobacterium Thermosynechococcus elongatus differs from proteobacterial Omp85 in structure and domain composition. J Biol Chem (2010) 1.07
TP0326, a Treponema pallidum β-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein. Mol Microbiol (2011) 1.06
Opr86 is essential for viability and is a potential candidate for a protective antigen against biofilm formation by Pseudomonas aeruginosa. J Bacteriol (2008) 1.06
Filling the gap, evolutionarily conserved Omp85 in plastids of chromalveolates. J Biol Chem (2009) 1.06
Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol (2016) 1.05
Outer membrane machinery and alginate synthesis regulators control membrane vesicle production in Pseudomonas aeruginosa. J Bacteriol (2009) 1.05
Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways. PLoS Genet (2011) 1.05
High-resolution structure of a new crystal form of BamA POTRA4-5 from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 1.05
Role of the periplasmic chaperones Skp, SurA, and DegQ in outer membrane protein biogenesis in Neisseria meningitidis. J Bacteriol (2011) 1.04
Characterization of multiprotein complexes of the Borrelia burgdorferi outer membrane vesicles. J Proteome Res (2011) 1.04
On the essentiality of lipopolysaccharide to Gram-negative bacteria. Curr Opin Microbiol (2013) 1.04
The protein-disulfide isomerase DsbC cooperates with SurA and DsbA in the assembly of the essential β-barrel protein LptD. J Biol Chem (2010) 1.03
Two-partner secretion of gram-negative bacteria: a single β-barrel protein enables transport across the outer membrane. J Biol Chem (2011) 1.02
The YfgL lipoprotein is essential for type III secretion system expression and virulence of Salmonella enterica Serovar Enteritidis. Infect Immun (2006) 1.02
The β-barrel membrane protein insertase machinery from Gram-negative bacteria. Curr Opin Struct Biol (2015) 1.02
Signal integration by DegS and RseB governs the σ E-mediated envelope stress response in Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.02
Structural basis of outer membrane protein insertion by the BAM complex. Nature (2016) 1.01
Conserved residues of the putative L6 loop of Escherichia coli BamA play a critical role in the assembly of β-barrel outer membrane proteins, including that of BamA itself. J Bacteriol (2012) 1.01
Substitutions in the BamA β-barrel domain overcome the conditional lethal phenotype of a ΔbamB ΔbamE strain of Escherichia coli. J Bacteriol (2011) 1.00
The bacterial cell envelope. Cold Spring Harb Perspect Biol (2010) 5.14
Structure and function of an essential component of the outer membrane protein assembly machine. Science (2007) 3.85
Reconstitution of outer membrane protein assembly from purified components. Science (2010) 3.30
Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev (2007) 3.24
Advances in understanding bacterial outer-membrane biogenesis. Nat Rev Microbiol (2006) 3.23
Chemical conditionality: a genetic strategy to probe organelle assembly. Cell (2005) 3.12
Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A (2007) 3.09
Sensing external stress: watchdogs of the Escherichia coli cell envelope. Curr Opin Microbiol (2005) 3.09
Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2006) 2.87
YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol Microbiol (2006) 2.84
Imp/OstA is required for cell envelope biogenesis in Escherichia coli. Mol Microbiol (2002) 2.72
Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway. Proc Natl Acad Sci U S A (2002) 2.68
β-Barrel membrane protein assembly by the Bam complex. Annu Rev Biochem (2011) 2.55
Quality control in the bacterial periplasm. Biochim Biophys Acta (2004) 2.29
Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Mol Microbiol (2008) 2.27
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2008) 2.21
An open letter to Elias Zerhouni. Science (2005) 2.19
Signal detection and target gene induction by the CpxRA two-component system. J Bacteriol (2003) 2.16
Transport of lipopolysaccharide across the cell envelope: the long road of discovery. Nat Rev Microbiol (2009) 2.07
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli. J Bacteriol (2008) 1.97
Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate. Proc Natl Acad Sci U S A (2003) 1.96
Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY. Science (2009) 1.96
The Bam machine: a molecular cooper. Biochim Biophys Acta (2011) 1.92
Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli. Proc Natl Acad Sci U S A (2012) 1.91
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chem Biol (2002) 1.90
Probing the barrier function of the outer membrane with chemical conditionality. ACS Chem Biol (2006) 1.86
Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A (2010) 1.85
An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A (2009) 1.81
Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics (2009) 1.75
Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis. Proc Natl Acad Sci U S A (2007) 1.68
The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel. Proc Natl Acad Sci U S A (2011) 1.68
Kinetic analysis of the assembly of the outer membrane protein LamB in Escherichia coli mutants each lacking a secretion or targeting factor in a different cellular compartment. J Bacteriol (2006) 1.66
Complex spatial distribution and dynamics of an abundant Escherichia coli outer membrane protein, LamB. Mol Microbiol (2004) 1.66
The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58
prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli. J Mol Biol (2007) 1.57
Proteins required for lipopolysaccharide assembly in Escherichia coli form a transenvelope complex. Biochemistry (2010) 1.54
Nonconsecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci U S A (2010) 1.48
Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for β-barrel assembly in Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.42
Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.41
Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. J Bacteriol (2005) 1.41
Escherichia coli starvation diets: essential nutrients weigh in distinctly. J Bacteriol (2005) 1.40
Distinct single-cell morphological dynamics under beta-lactam antibiotics. Mol Cell (2012) 1.39
Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli. Science (2012) 1.37
Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. J Am Chem Soc (2011) 1.37
Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. J Biol Chem (2007) 1.36
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol (2005) 1.35
Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export. Biochemistry (2012) 1.35
The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics. J Bacteriol (2013) 1.31
Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria. Curr Opin Microbiol (2012) 1.31
Secretion of LamB-LacZ by the signal recognition particle pathway of Escherichia coli. J Bacteriol (2003) 1.30
Constitutive activation of the Escherichia coli Pho regulon upregulates rpoS translation in an Hfq-dependent fashion. J Bacteriol (2003) 1.30
Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery. Proc Natl Acad Sci U S A (2009) 1.29
The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli. Mol Microbiol (2011) 1.27
Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. J Am Chem Soc (2005) 1.23
Continuous control in bacterial regulatory circuits. J Bacteriol (2004) 1.22
The art and design of genetic screens: Escherichia coli. Nat Rev Genet (2003) 1.19
Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design. ACS Chem Biol (2008) 1.19
Complete characterization of the seventeen step moenomycin biosynthetic pathway. Biochemistry (2009) 1.19
Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II. J Am Chem Soc (2013) 1.18
AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A. Chem Biol (2005) 1.18
The reconstituted Escherichia coli Bam complex catalyzes multiple rounds of β-barrel assembly. Biochemistry (2011) 1.17
Crl facilitates RNA polymerase holoenzyme formation. J Bacteriol (2006) 1.17
A suppressor of cell death caused by the loss of sigmaE downregulates extracytoplasmic stress responses and outer membrane vesicle production in Escherichia coli. J Bacteriol (2006) 1.16
BamE modulates the Escherichia coli beta-barrel assembly machine component BamA. J Bacteriol (2011) 1.15
The structural basis for induction of VanB resistance. J Am Chem Soc (2002) 1.15
D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. J Bacteriol (2013) 1.15
In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. J Am Chem Soc (2005) 1.13
Starvation for different nutrients in Escherichia coli results in differential modulation of RpoS levels and stability. J Bacteriol (2005) 1.13
Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate. Proc Natl Acad Sci U S A (2012) 1.12
Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export. Science (2012) 1.11
Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigmaS upon carbon starvation. Genes Dev (2007) 1.11
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. J Am Chem Soc (2010) 1.11
Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. J Am Chem Soc (2013) 1.10
Isolated peptidoglycan glycosyltransferases from different organisms produce different glycan chain lengths. J Am Chem Soc (2008) 1.09
The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains. J Bacteriol (2013) 1.08
RpoS proteolysis is regulated by a mechanism that does not require the SprE (RssB) response regulator phosphorylation site. J Bacteriol (2004) 1.07