Published in Biochemistry on May 24, 2005
Asymmetric lower-limb malformations in individuals with homeobox PITX1 gene mutation. Am J Hum Genet (2008) 1.21
Microphthalmia in Texel sheep is associated with a missense mutation in the paired-like homeodomain 3 (PITX3) gene. PLoS One (2010) 1.18
Transcriptional regulation and stabilization of left-right neuronal identity in C. elegans. Genes Dev (2009) 1.17
Paired-like homeodomain transcription factors 1 and 2 regulate follicle-stimulating hormone beta-subunit transcription through a conserved cis-element. Endocrinology (2008) 0.97
A zebrafish model of axenfeld-rieger syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development. Invest Ophthalmol Vis Sci (2012) 0.94
Transcription factor heterogeneity and epiblast pluripotency. Philos Trans R Soc Lond B Biol Sci (2011) 0.92
1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain and a R24H homeodomain mutant. Biomol NMR Assign (2010) 0.89
Discovery, optimization and validation of an optimal DNA-binding sequence for the Six1 homeodomain transcription factor. Nucleic Acids Res (2012) 0.88
Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations. Genome Res (2013) 0.86
Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding. PLoS Genet (2012) 0.85
FIZ1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo. BMC Mol Biol (2008) 0.84
Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone beta subunit transcription. Mol Hum Reprod (2008) 0.83
A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency. Hum Genet (2010) 0.83
Transcription factor family-specific DNA shape readout revealed by quantitative specificity models. Mol Syst Biol (2017) 0.79
Structural and biophysical insights into the ligand-free Pitx2 homeodomain and a ring dermoid of the cornea inducing homeodomain mutant. Biochemistry (2012) 0.79
The Ets factor Etv1 interacts with Tpit protein for pituitary pro-opiomelanocortin (POMC) gene transcription. J Biol Chem (2011) 0.79
The structures that underlie normal reproductive function. Mol Cell Endocrinol (2006) 0.78
Regulatory logic driving stable levels of defective proventriculus expression during terminal photoreceptor specification in flies. Development (2017) 0.75
¹H, ¹³C and ¹⁵N chemical shift assignments for the human Pitx2 homeodomain in complex with a 22-base hairpin DNA. Biomol NMR Assign (2011) 0.75
Dynamic Local Polymorphisms in the Gbx1 Homeodomain Induced by DNA Binding. Structure (2016) 0.75
Pitx2 in Embryonic and Adult Myogenesis. Front Cell Dev Biol (2017) 0.75
Mutations in zebrafish pitx2 model congenital malformations in Axenfeld-Rieger syndrome but do not disrupt left-right placement of visceral organs. Dev Biol (2016) 0.75
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol (2011) 18.34
Electronic health record use and the quality of ambulatory care in the United States. Arch Intern Med (2007) 5.85
How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients? Int J Radiat Oncol Biol Phys (2010) 4.14
Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature (2011) 3.32
Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91
The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. J Lab Clin Med (2006) 2.90
Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial. Lancet Oncol (2011) 2.75
Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: a pooled data analysis of two phase III trials. J Clin Oncol (2005) 2.49
Comparison of dynamic block randomization and minimization in randomized trials: a simulation study. Clin Trials (2011) 2.22
Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders. Cell Cycle (2011) 2.19
Baseline serum lactate dehydrogenase levels for patients treated with intensity-modulated radiotherapy for nasopharyngeal carcinoma: a predictor of poor prognosis and subsequent liver metastasis. Int J Radiat Oncol Biol Phys (2011) 1.99
A metagenomic approach to characterization of the vaginal microbiome signature in pregnancy. PLoS One (2012) 1.98
Inhibiting the regeneration of N-nitrosodimethylamine in drinking water by UV photolysis combined with ozonation. J Hazard Mater (2009) 1.92
Impact of clinical trial results on national trends in alpha-blocker prescribing, 1996-2002. JAMA (2004) 1.85
Long-term and short-term changes in antihypertensive prescribing by office-based physicians in the United States. Hypertension (2006) 1.82
P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes. Biol Reprod (2010) 1.77
Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression. Epigenetics (2011) 1.76
Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae). Phytochemistry (2007) 1.74
Is primary tumor volume still a prognostic factor in intensity modulated radiation therapy for nasopharyngeal carcinoma? Radiother Oncol (2012) 1.72
Preliminary results of a prospective randomized trial comparing concurrent chemoradiotherapy plus adjuvant chemotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma in endemic regions of china. Int J Radiat Oncol Biol Phys (2008) 1.71
A blood-based biomarker panel for stratifying current risk for colorectal cancer. Int J Cancer (2010) 1.70
Trends in blood pressure and body mass index among Chinese children and adolescents from 2005 to 2010. Am J Hypertens (2013) 1.70
The seventh edition of the UICC/AJCC staging system for nasopharyngeal carcinoma is prognostically useful for patients treated with intensity-modulated radiotherapy from an endemic area in China. Radiother Oncol (2011) 1.60
Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. Am J Pathol (2007) 1.59
Extended transsternal thymectomy for the treatment of ocular myasthenia gravis. Ann Thorac Surg (2011) 1.58
The association of weight with the detection of airflow obstruction and inhaled treatment among patients with a clinical diagnosis of COPD. Chest (2014) 1.51
Current Science on Consumer Use of Mobile Health for Cardiovascular Disease Prevention: A Scientific Statement From the American Heart Association. Circulation (2015) 1.48
Probing intrinsic properties of a robust morphogen gradient in Drosophila. Dev Cell (2008) 1.48
NMR R1 rho rotating-frame relaxation with weak radio frequency fields. J Am Chem Soc (2004) 1.46
The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma: analysis of the spread patterns in lymph nodes by magnetic resonance imaging. Cancer (2009) 1.45
Extension of local disease in nasopharyngeal carcinoma detected by magnetic resonance imaging: improvement of clinical target volume delineation. Int J Radiat Oncol Biol Phys (2009) 1.45
How does magnetic resonance imaging influence staging according to AJCC staging system for nasopharyngeal carcinoma compared with computed tomography? Int J Radiat Oncol Biol Phys (2008) 1.44
Secular trends of obesity prevalence in urban Chinese children from 1985 to 2010: gender disparity. PLoS One (2013) 1.43
Oxidation of sulfoxides and arsenic(III) in corrosion of nanoscale zero valent iron by oxygen: evidence against ferryl ions (Fe(IV)) as active intermediates in Fenton reaction. Environ Sci Technol (2010) 1.42
The N staging system in nasopharyngeal carcinoma with radiation therapy oncology group guidelines for lymph node levels based on magnetic resonance imaging. Clin Cancer Res (2008) 1.41
Underutilization of aspirin persists in US ambulatory care for the secondary and primary prevention of cardiovascular disease. PLoS Med (2005) 1.41
Waist Circumference is Better Than Other Anthropometric Indices for Predicting Cardiovascular Disease Risk Factors in Chinese Children-a Cross-Sectional Study in Guangzhou. J Atheroscler Thromb (2015) 1.40
Association of INSIG2 rs9308762 with ALT level independent of BMI. J Pediatr Gastroenterol Nutr (2014) 1.40
Effects of interleukin-10 on cutaneous wounds and scars in humans of African continental ancestral origin. Wound Repair Regen (2014) 1.39
Mapping chemical exchange in proteins with MW > 50 kD. J Am Chem Soc (2003) 1.36
Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol Cell Biol (2010) 1.35
Tumor detection and elimination by a targeted gallium corrole. Proc Natl Acad Sci U S A (2009) 1.34
Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma detected by magnetic resonance imaging : prognostic value and staging categories. Cancer (2008) 1.33
Prognostic impact of magnetic resonance imaging-detected cranial nerve involvement in nasopharyngeal carcinoma. Cancer (2009) 1.33
Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner. J Biol Chem (2006) 1.33
Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development. Development (2008) 1.32
Homoharringtonine-based induction regimens for patients with de-novo acute myeloid leukaemia: a multicentre, open-label, randomised, controlled phase 3 trial. Lancet Oncol (2013) 1.31
Genetic relationships between resistances to Fusarium head blight and crown rot in bread wheat (Triticum aestivum L.). Theor Appl Genet (2010) 1.30
Re-evaluation of 6th edition of AJCC staging system for nasopharyngeal carcinoma and proposed improvement based on magnetic resonance imaging. Int J Radiat Oncol Biol Phys (2009) 1.29
Prognostic value of subclassification using MRI in the t4 classification nasopharyngeal carcinoma intensity-modulated radiotherapy treatment. Int J Radiat Oncol Biol Phys (2012) 1.28
NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction. Mol Cancer (2014) 1.27
DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV. Proc Natl Acad Sci U S A (2013) 1.27
National trends in asthma visits and asthma pharmacotherapy, 1978-2002. J Allergy Clin Immunol (2003) 1.26
Toward quantitative interpretation of methyl side-chain dynamics from NMR by molecular dynamics simulations. J Am Chem Soc (2007) 1.26
Protein side-chain dynamics and residual conformational entropy. J Am Chem Soc (2009) 1.25
MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma. Cancer Lett (2012) 1.23
Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. PLoS Pathog (2013) 1.22
Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. Int J Cancer (2007) 1.21
Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism. Structure (2012) 1.21
Locoregional extension patterns of nasopharyngeal carcinoma and suggestions for clinical target volume delineation. Chin J Cancer (2012) 1.20
Oral tetra-arsenic tetra-sulfide formula versus intravenous arsenic trioxide as first-line treatment of acute promyelocytic leukemia: a multicenter randomized controlled trial. J Clin Oncol (2013) 1.19
Replicative senescence of human bone marrow and umbilical cord derived mesenchymal stem cells and their differentiation to adipocytes and osteoblasts. Mol Biol Rep (2010) 1.19
Multiple time scale backbone dynamics of homologous thermophilic and mesophilic ribonuclease HI enzymes. J Mol Biol (2004) 1.19
Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders. Cell Cycle (2009) 1.16
Coordinated changes in dendritic arborization and synaptic strength during neural circuit development. Neuron (2009) 1.13
Synthetic access to the chlorocyclopentane cores of the proposed original and revised structures of palau'amine. Angew Chem Int Ed Engl (2008) 1.13
HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China. Int J Infect Dis (2007) 1.13
Promising treatment outcomes of intensity-modulated radiation therapy for nasopharyngeal carcinoma patients with N0 disease according to the seventh edition of the AJCC staging system. BMC Cancer (2012) 1.13
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer. PLoS One (2011) 1.12
Underdiagnosis of obesity in adults in US outpatient settings. Arch Intern Med (2009) 1.12
Aurora kinase B modulates chromosome alignment in mouse oocytes. Mol Reprod Dev (2009) 1.12
Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry (2006) 1.12
Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals. Obesity (Silver Spring) (2009) 1.12
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma. Dis Esophagus (2009) 1.12
The activity of the Drosophila morphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain. Development (2002) 1.11
A four-miRNA signature identified from genome-wide serum miRNA profiling predicts survival in patients with nasopharyngeal carcinoma. Int J Cancer (2013) 1.10
Activation tagging, an efficient tool for functional analysis of the rice genome. Plant Mol Biol (2008) 1.10
A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study. J Diabetes Complications (2008) 1.10
Prognostic value and staging categories of anatomic masticator space involvement in nasopharyngeal carcinoma: a study of 924 cases with MR imaging. Radiology (2010) 1.10
Signaling pathways in the epithelial origins of pulmonary fibrosis. Cell Cycle (2010) 1.10
Complete coding sequences and phylogenetic analysis of porcine bocavirus. J Gen Virol (2011) 1.09
Self-efficacy, perceived benefits, and weight satisfaction discriminate among stages of change for fruit and vegetable intakes for young men and women. J Am Diet Assoc (2002) 1.08
Dynamics of ATP-binding cassette contribute to allosteric control, nucleotide binding and energy transduction in ABC transporters. J Mol Biol (2004) 1.08
Waist circumference distribution of Chinese school-age children and adolescents. Biomed Environ Sci (2010) 1.08
An atlas-based geometry pipeline for cardiac Hermite model construction and diffusion tensor reorientation. Med Image Anal (2012) 1.06
The Genboree Microbiome Toolset and the analysis of 16S rRNA microbial sequences. BMC Bioinformatics (2012) 1.05
Comment on Electrolytic manipulation of persulfate reactivity by iron electrodes for TCE degradation in groundwater. Environ Sci Technol (2014) 1.05
Saponins from the traditional medicinal plant Momordica charantia stimulate insulin secretion in vitro. Phytomedicine (2011) 1.05
Alpha B-crystallin is a new prognostic marker for laryngeal squamous cell carcinoma. J Exp Clin Cancer Res (2012) 1.05
Radiation-induced temporal lobe injury for nasopharyngeal carcinoma: a comparison of intensity-modulated radiotherapy and conventional two-dimensional radiotherapy. PLoS One (2013) 1.04
Dietary pattern and its association with the prevalence of obesity and related cardiometabolic risk factors among Chinese children. PLoS One (2012) 1.04
Epidemiological and clinical features of Moyamoya disease in Nanjing, China. Clin Neurol Neurosurg (2009) 1.04
Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells. Biochem J (2012) 1.04
Proposed lymph node staging system using the International Consensus Guidelines for lymph node levels is predictive for nasopharyngeal carcinoma patients from endemic areas treated with intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys (2012) 1.04
Nucleocytoplasmic shuttling of receptor-interacting protein 3 (RIP3): identification of novel nuclear export and import signals in RIP3. J Biol Chem (2004) 1.03
Shaping a morphogen gradient for positional precision. Biophys J (2010) 1.03
Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis. J Immunol (2011) 1.03