Published in Cell Cycle on October 15, 2011
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Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies. J Clin Immunol (2012) 0.93
Ultra-rare mutation in long-range enhancer predisposes to thyroid carcinoma with high penetrance. PLoS One (2013) 0.88
Identifying causal regulatory SNPs in ChIP-seq enhancers. Nucleic Acids Res (2014) 0.85
Transcriptional targeting by microRNA-polycomb complexes: a novel route in cell fate determination. Cell Cycle (2012) 0.83
RNA-guided diagnostics and therapeutics for next-generation individualized nanomedicine. J Clin Invest (2013) 0.78
Genome-wide analysis of functional and evolutionary features of tele-enhancers. G3 (Bethesda) (2014) 0.76
Explaining the disease phenotype of intergenic SNP through predicted long range regulation. Nucleic Acids Res (2016) 0.76
Micro RNAs and DNA methylation are regulatory players in human cells with altered X chromosome to autosome balance. Sci Rep (2017) 0.75
Bridging the gaps: from risk loci via non-coding RNAs to gene networks and prostate cancer phenotypes. Cell Cycle (2011) 0.75
The riddle of intergenic disease-associated loci. Cell Cycle (2012) 0.75
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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet (2007) 32.41
Systematic determination of genetic network architecture. Nat Genet (1999) 25.45
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science (2007) 18.59
ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature (2009) 18.38
Global identification of human transcribed sequences with genome tiling arrays. Science (2004) 17.85
Widespread transcription at neuronal activity-regulated enhancers. Nature (2010) 16.52
Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet (2007) 14.37
A common variant associated with prostate cancer in European and African populations. Nat Genet (2006) 13.47
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet (2007) 11.62
Genomewide association studies and assessment of the risk of disease. N Engl J Med (2010) 11.51
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet (2008) 11.17
Divergent transcription from active promoters. Science (2008) 11.03
Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci U S A (2006) 10.32
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet (2007) 9.88
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A common genetic risk factor for colorectal and prostate cancer. Nat Genet (2007) 7.11
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet (2009) 6.99
Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs. Nature (2009) 6.88
Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome. PLoS Genet (2007) 5.93
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest (2005) 5.90
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Gene expression profiling predicts clinical outcome of prostate cancer. J Clin Invest (2004) 4.59
Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet (2011) 3.73
Functional enhancers at the gene-poor 8q24 cancer-linked locus. PLoS Genet (2009) 3.59
Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature (2009) 3.03
Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells. Mol Cell Biol (2010) 2.80
Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs. Nature (2008) 2.78
Multiple prostate cancer risk variants on 8q24. Nat Genet (2007) 2.76
Structured RNAs in the ENCODE selected regions of the human genome. Genome Res (2007) 2.69
Long-range enhancers on 8q24 regulate c-Myc. Proc Natl Acad Sci U S A (2010) 2.54
A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes Dev (2007) 2.48
EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res (2011) 2.32
Origin of phenotypes: genes and transcripts. Genome Res (2007) 2.30
An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer. Genome Res (2010) 2.24
Phenotype-defining functions of multiple non-coding RNA pathways. Cell Cycle (2008) 1.57
The DART classification of unannotated transcription within the ENCODE regions: associating transcription with known and novel loci. Genome Res (2007) 1.56
A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci (2010) 1.47
Joint influence of small-effect genetic variants on human longevity. Aging (Albany NY) (2010) 1.16
Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders. Cell Cycle (2009) 1.16
An SNP-guided microRNA map of fifteen common human disorders identifies a consensus disease phenocode aiming at principal components of the nuclear import pathway. Cell Cycle (2008) 1.14
Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population. Aging (Albany NY) (2009) 1.13
Resistance to apoptosis in human cells conferred by telomerase function and telomere stability. Mol Carcinog (1999) 1.06
Microarray analysis of xenograft-derived cancer cell lines representing multiple experimental models of human prostate cancer. Mol Carcinog (2003) 1.04
Integration of HapMap-based SNP pattern analysis and gene expression profiling reveals common SNP profiles for cancer therapy outcome predictor genes. Cell Cycle (2006) 0.99
A systematic approach to understand the functional consequences of non-protein coding risk regions. Cell Cycle (2010) 0.96
SNP-guided microRNA maps (MirMaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways. Cell Cycle (2008) 0.94
Classification of human breast cancer using gene expression profiling as a component of the survival predictor algorithm. Clin Cancer Res (2004) 0.94
Disease phenocode analysis identifies SNP-guided microRNA maps (MirMaps) associated with human "master" disease genes. Cell Cycle (2008) 0.93
Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population. Aging (Albany NY) (2011) 0.92
SNP'ing for longevity. Aging (Albany NY) (2009) 0.88
MicroRNAs in neurodegenerative disorders. Cell Cycle (2010) 0.84
Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma. Oncotarget (2010) 0.80
Human genome connectivity code links disease-associated SNPs, microRNAs and pyknons. Cell Cycle (2009) 0.79
Remarkable features of tiny RNA molecules: highlights of revolutionary discoveries on the path from the bench to bedside. Cell Cycle (2008) 0.78
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol (2011) 18.34
Electronic health record use and the quality of ambulatory care in the United States. Arch Intern Med (2007) 5.85
How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients? Int J Radiat Oncol Biol Phys (2010) 4.14
Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature (2011) 3.32
Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91
The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. J Lab Clin Med (2006) 2.90
Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial. Lancet Oncol (2011) 2.75
IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge. J Immunol (2009) 2.74
Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: a pooled data analysis of two phase III trials. J Clin Oncol (2005) 2.49
Comparison of dynamic block randomization and minimization in randomized trials: a simulation study. Clin Trials (2011) 2.22
Baseline serum lactate dehydrogenase levels for patients treated with intensity-modulated radiotherapy for nasopharyngeal carcinoma: a predictor of poor prognosis and subsequent liver metastasis. Int J Radiat Oncol Biol Phys (2011) 1.99
A metagenomic approach to characterization of the vaginal microbiome signature in pregnancy. PLoS One (2012) 1.98
Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium. Cancer Res (2003) 1.97
Inhibiting the regeneration of N-nitrosodimethylamine in drinking water by UV photolysis combined with ozonation. J Hazard Mater (2009) 1.92
Impact of clinical trial results on national trends in alpha-blocker prescribing, 1996-2002. JAMA (2004) 1.85
Long-term and short-term changes in antihypertensive prescribing by office-based physicians in the United States. Hypertension (2006) 1.82
P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes. Biol Reprod (2010) 1.77
Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression. Epigenetics (2011) 1.76
Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae). Phytochemistry (2007) 1.74
Is primary tumor volume still a prognostic factor in intensity modulated radiation therapy for nasopharyngeal carcinoma? Radiother Oncol (2012) 1.72
Preliminary results of a prospective randomized trial comparing concurrent chemoradiotherapy plus adjuvant chemotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma in endemic regions of china. Int J Radiat Oncol Biol Phys (2008) 1.71
A blood-based biomarker panel for stratifying current risk for colorectal cancer. Int J Cancer (2010) 1.70
Trends in blood pressure and body mass index among Chinese children and adolescents from 2005 to 2010. Am J Hypertens (2013) 1.70
Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer. Cell Cycle (2006) 1.69
Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells. Cancer Res (2005) 1.66
The seventh edition of the UICC/AJCC staging system for nasopharyngeal carcinoma is prognostically useful for patients treated with intensity-modulated radiotherapy from an endemic area in China. Radiother Oncol (2011) 1.60
Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. Am J Pathol (2007) 1.59
Extended transsternal thymectomy for the treatment of ocular myasthenia gravis. Ann Thorac Surg (2011) 1.58
Beta-catenin-related anomalies in apoptosis-resistant and hormone-refractory prostate cancer cells. Clin Cancer Res (2003) 1.52
The association of weight with the detection of airflow obstruction and inhaled treatment among patients with a clinical diagnosis of COPD. Chest (2014) 1.51
Current Science on Consumer Use of Mobile Health for Cardiovascular Disease Prevention: A Scientific Statement From the American Heart Association. Circulation (2015) 1.48
Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs. Neoplasia (2005) 1.48
Probing intrinsic properties of a robust morphogen gradient in Drosophila. Dev Cell (2008) 1.48
Multifaceted interaction between the androgen and Wnt signaling pathways and the implication for prostate cancer. J Cell Biochem (2006) 1.47
The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma: analysis of the spread patterns in lymph nodes by magnetic resonance imaging. Cancer (2009) 1.45
Extension of local disease in nasopharyngeal carcinoma detected by magnetic resonance imaging: improvement of clinical target volume delineation. Int J Radiat Oncol Biol Phys (2009) 1.45
How does magnetic resonance imaging influence staging according to AJCC staging system for nasopharyngeal carcinoma compared with computed tomography? Int J Radiat Oncol Biol Phys (2008) 1.44
Secular trends of obesity prevalence in urban Chinese children from 1985 to 2010: gender disparity. PLoS One (2013) 1.43
Unexpected artifacts raise new caution in stem cell culture research. Hepatology (2004) 1.42
Oxidation of sulfoxides and arsenic(III) in corrosion of nanoscale zero valent iron by oxygen: evidence against ferryl ions (Fe(IV)) as active intermediates in Fenton reaction. Environ Sci Technol (2010) 1.42
The N staging system in nasopharyngeal carcinoma with radiation therapy oncology group guidelines for lymph node levels based on magnetic resonance imaging. Clin Cancer Res (2008) 1.41
Underutilization of aspirin persists in US ambulatory care for the secondary and primary prevention of cardiovascular disease. PLoS Med (2005) 1.41
Inflammatory chemokine receptors regulate CD8(+) T cell contraction and memory generation following infection. J Exp Med (2011) 1.40
Association of INSIG2 rs9308762 with ALT level independent of BMI. J Pediatr Gastroenterol Nutr (2014) 1.40
Waist Circumference is Better Than Other Anthropometric Indices for Predicting Cardiovascular Disease Risk Factors in Chinese Children-a Cross-Sectional Study in Guangzhou. J Atheroscler Thromb (2015) 1.40
Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol Cell Biol (2010) 1.35
Tumor detection and elimination by a targeted gallium corrole. Proc Natl Acad Sci U S A (2009) 1.34
Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma detected by magnetic resonance imaging : prognostic value and staging categories. Cancer (2008) 1.33
Prognostic impact of magnetic resonance imaging-detected cranial nerve involvement in nasopharyngeal carcinoma. Cancer (2009) 1.33
Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner. J Biol Chem (2006) 1.33
Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development. Development (2008) 1.32
Homoharringtonine-based induction regimens for patients with de-novo acute myeloid leukaemia: a multicentre, open-label, randomised, controlled phase 3 trial. Lancet Oncol (2013) 1.31
Genetic relationships between resistances to Fusarium head blight and crown rot in bread wheat (Triticum aestivum L.). Theor Appl Genet (2010) 1.30
Re-evaluation of 6th edition of AJCC staging system for nasopharyngeal carcinoma and proposed improvement based on magnetic resonance imaging. Int J Radiat Oncol Biol Phys (2009) 1.29
Prognostic value of subclassification using MRI in the t4 classification nasopharyngeal carcinoma intensity-modulated radiotherapy treatment. Int J Radiat Oncol Biol Phys (2012) 1.28
MDA-MB-435 human breast carcinoma cell homo- and heterotypic adhesion under flow conditions is mediated in part by Thomsen-Friedenreich antigen-galectin-3 interactions. J Biol Chem (2002) 1.28
Viable circulating metastatic cells produced in orthotopic but not ectopic prostate cancer models. Cancer Res (2003) 1.28
NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction. Mol Cancer (2014) 1.27
DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV. Proc Natl Acad Sci U S A (2013) 1.27
National trends in asthma visits and asthma pharmacotherapy, 1978-2002. J Allergy Clin Immunol (2003) 1.26
MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma. Cancer Lett (2012) 1.23
Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. PLoS Pathog (2013) 1.22
A human- and male-specific protocadherin that acts through the wnt signaling pathway to induce neuroendocrine transdifferentiation of prostate cancer cells. Cancer Res (2005) 1.22
Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. Int J Cancer (2007) 1.21
Locoregional extension patterns of nasopharyngeal carcinoma and suggestions for clinical target volume delineation. Chin J Cancer (2012) 1.20
Replicative senescence of human bone marrow and umbilical cord derived mesenchymal stem cells and their differentiation to adipocytes and osteoblasts. Mol Biol Rep (2010) 1.19
Oral tetra-arsenic tetra-sulfide formula versus intravenous arsenic trioxide as first-line treatment of acute promyelocytic leukemia: a multicenter randomized controlled trial. J Clin Oncol (2013) 1.19
Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy. Cancer Res (2010) 1.18
Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders. Cell Cycle (2009) 1.16
Antigen-specific memory regulatory CD4+Foxp3+ T cells control memory responses to influenza virus infection. J Immunol (2013) 1.16
Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome. Biochemistry (2005) 1.16
Coordinated changes in dendritic arborization and synaptic strength during neural circuit development. Neuron (2009) 1.13
HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China. Int J Infect Dis (2007) 1.13
Synthetic access to the chlorocyclopentane cores of the proposed original and revised structures of palau'amine. Angew Chem Int Ed Engl (2008) 1.13
Promising treatment outcomes of intensity-modulated radiation therapy for nasopharyngeal carcinoma patients with N0 disease according to the seventh edition of the AJCC staging system. BMC Cancer (2012) 1.13
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer. PLoS One (2011) 1.12
Underdiagnosis of obesity in adults in US outpatient settings. Arch Intern Med (2009) 1.12
Aurora kinase B modulates chromosome alignment in mouse oocytes. Mol Reprod Dev (2009) 1.12
Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry (2006) 1.12
Acute hypoxia increases the aggressive characteristics and survival properties of prostate cancer cells. Prostate (2003) 1.12
Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals. Obesity (Silver Spring) (2009) 1.12
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma. Dis Esophagus (2009) 1.12
The activity of the Drosophila morphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain. Development (2002) 1.11
A four-miRNA signature identified from genome-wide serum miRNA profiling predicts survival in patients with nasopharyngeal carcinoma. Int J Cancer (2013) 1.10
Activation tagging, an efficient tool for functional analysis of the rice genome. Plant Mol Biol (2008) 1.10
Prognostic value and staging categories of anatomic masticator space involvement in nasopharyngeal carcinoma: a study of 924 cases with MR imaging. Radiology (2010) 1.10
A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study. J Diabetes Complications (2008) 1.10
Complete coding sequences and phylogenetic analysis of porcine bocavirus. J Gen Virol (2011) 1.09
Self-efficacy, perceived benefits, and weight satisfaction discriminate among stages of change for fruit and vegetable intakes for young men and women. J Am Diet Assoc (2002) 1.08
Galectin-3 as a potential therapeutic target in tumors arising from malignant endothelia. Neoplasia (2007) 1.08
Complementary and alternative medicine for chronic prostatitis/chronic pelvic pain syndrome. Evid Based Complement Alternat Med (2005) 1.08
Waist circumference distribution of Chinese school-age children and adolescents. Biomed Environ Sci (2010) 1.08
Hepatocyte nuclear factor-1 as marker of epithelial phenotype reveals marrow-derived hepatocytes, but not duct cells, after liver injury in mice. Stem Cells (2008) 1.06