Synthetic access to the chlorocyclopentane cores of the proposed original and revised structures of palau'amine.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMC 2610474)

Published in Angew Chem Int Ed Engl on January 01, 2008

Authors

Michael S Bultman1, Jun Ma, David Y Gin

Author Affiliations

1: Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

Articles citing this

Total synthesis of palau'amine. Angew Chem Int Ed Engl (2010) 2.62

Total syntheses of (+/-)-massadine and massadine chloride. J Am Chem Soc (2008) 1.26

Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines. J Am Chem Soc (2011) 1.25

Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine. Chem Commun (Camb) (2010) 1.12

Exploring symmetry-based logic for a synthesis of palau'amine. J Org Chem (2009) 1.09

Synthetic Studies on Palau'amine. Construction of the Cyclopentane Core via an Asymmetric 1,3-Dipolar Cycloaddition. Tetrahedron Lett (2010) 0.93

Syntheses of Cyclic Guanidine-Containing Natural Products. Tetrahedron (2015) 0.92

Asymmetric synthesis of ageliferin. J Am Chem Soc (2011) 0.92

A biomimetic route for construction of the [4+2] and [3+2] core skeletons of dimeric pyrrole-imidazole alkaloids and asymmetric synthesis of ageliferins. J Am Chem Soc (2012) 0.89

Toward palau'amine: Hg(OTf)2-catalyzed synthesis of the cyclopentane core. Chemistry (2009) 0.89

Synthetic (±)-axinellamines deficient in halogen. Angew Chem Int Ed Engl (2012) 0.87

Microwave-based reaction screening: tandem retro-Diels-Alder/Diels-Alder cycloadditions of o-quinol dimers. J Org Chem (2011) 0.84

Dimeric pyrrole-imidazole alkaloids: synthetic approaches and biosynthetic hypotheses. Chem Commun (Camb) (2014) 0.83

Total synthesis of palau'amine. Nat Commun (2015) 0.76

Asymmetric Synthesis of Axinellamines A and B. Angew Chem Int Ed Engl (2016) 0.75

The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol. ACS Med Chem Lett (2012) 0.75

Articles cited by this

The pursuit of palau'amine. Angew Chem Int Ed Engl (2007) 2.00

Structural assignment of tetrabromostyloguanidine: does the relative configuration of the palau'amines need revision? Angew Chem Int Ed Engl (2007) 1.44

Total synthesis of (+/-)-axinellamines A and B. Angew Chem Int Ed Engl (2008) 1.44

Natural products, stylissadines A and B, specific antagonists of the P2X7 receptor, an important inflammatory target. J Org Chem (2007) 1.41

Synthesis of 1,9-dideoxy-pre-axinellamine. Angew Chem Int Ed Engl (2008) 1.39

Regiocontrol in Mn(III)-mediated oxidative heterobicyclizations: access to the core skeletons of oroidin dimers. Angew Chem Int Ed Engl (2006) 1.38

Studies toward the total synthesis of axinellamine and massadine. Org Lett (2007) 1.35

Synthesis of marine alkaloids from the oroidin family. Angew Chem Int Ed Engl (2008) 1.24

Total synthesis of the cytostatic marine natural product dibromophakellstatin via three-component imidazolidinone anellation. J Org Chem (2006) 1.23

Oxidative rearrangement of imidazoles with dimethyldioxirane. Org Lett (2004) 1.19

Massadine chloride: a biosynthetic precursor of massadine and stylissadine. Angew Chem Int Ed Engl (2007) 1.19

Enantioselective synthesis of (+)-monobromophakellin and (+)-phakellin: a concise phakellin annulation strategy applicable to Palau'amine. Angew Chem Int Ed Engl (2008) 1.16

On the structure of palau'amine: evidence for the revised relative configuration from chemical synthesis. J Am Chem Soc (2007) 1.16

Enantioselective strategy to the spirocyclic core of Palau'amine and related bisguanidine marine alkaloids. Org Lett (2001) 1.13

Density functional theory guided design of exo-selective dehydroalanine dienophiles for application toward the synthesis of palau'amine. J Org Chem (2007) 1.06

Spirocycloisomerization of tethered alkylidene glycocyamidines: synthesis of a base template common to the palau'amine family of alkaloids. Angew Chem Int Ed Engl (2005) 1.06

Highly regioselective Diels-Alder reactions toward oroidin alkaloids: use of a tosylvinyl moiety as a nitrogen masking group with adjustable electronics. Org Lett (2005) 0.99

A transient N-O-linked Pauson-Khand strategy for the synthesis of the deschloro carbocyclic core of the palau'amines and styloguanidines. Org Lett (2003) 0.97

Direct access to marine pyrrole-2-aminoimidazoles, oroidin, and derivatives, via new acyl-1,2-dihydropyridin intermediates. Org Lett (2006) 0.97

Hypervalent iodine-mediated vicinal syn diazidation: application to the total synthesis of (+/-)-dibromophakellstatin. Org Lett (2004) 0.95

Extending Pummerer reaction chemistry. Synthesis of (+/-)-dibromophakellstatin by oxidative cyclization of an imidazole derivative. Org Lett (2005) 0.94

Debromodispacamides B and D: isolation from the marine sponge Agelas mauritiana and stereoselective synthesis using a biomimetic proline route. Org Lett (2008) 0.86

Articles by these authors

(truncated to the top 100)

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol (2011) 18.34

Electronic health record use and the quality of ambulatory care in the United States. Arch Intern Med (2007) 5.85

How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients? Int J Radiat Oncol Biol Phys (2010) 4.14

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity. Nature (2011) 3.37

Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature (2011) 3.32

Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91

The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. J Lab Clin Med (2006) 2.90

Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial. Lancet Oncol (2011) 2.75

Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: a pooled data analysis of two phase III trials. J Clin Oncol (2005) 2.49

Comparison of dynamic block randomization and minimization in randomized trials: a simulation study. Clin Trials (2011) 2.22

Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders. Cell Cycle (2011) 2.19

Baseline serum lactate dehydrogenase levels for patients treated with intensity-modulated radiotherapy for nasopharyngeal carcinoma: a predictor of poor prognosis and subsequent liver metastasis. Int J Radiat Oncol Biol Phys (2011) 1.99

A metagenomic approach to characterization of the vaginal microbiome signature in pregnancy. PLoS One (2012) 1.98

Inhibiting the regeneration of N-nitrosodimethylamine in drinking water by UV photolysis combined with ozonation. J Hazard Mater (2009) 1.92

Impact of clinical trial results on national trends in alpha-blocker prescribing, 1996-2002. JAMA (2004) 1.85

Long-term and short-term changes in antihypertensive prescribing by office-based physicians in the United States. Hypertension (2006) 1.82

P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes. Biol Reprod (2010) 1.77

Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression. Epigenetics (2011) 1.76

Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae). Phytochemistry (2007) 1.74

Is primary tumor volume still a prognostic factor in intensity modulated radiation therapy for nasopharyngeal carcinoma? Radiother Oncol (2012) 1.72

Preliminary results of a prospective randomized trial comparing concurrent chemoradiotherapy plus adjuvant chemotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma in endemic regions of china. Int J Radiat Oncol Biol Phys (2008) 1.71

A blood-based biomarker panel for stratifying current risk for colorectal cancer. Int J Cancer (2010) 1.70

Trends in blood pressure and body mass index among Chinese children and adolescents from 2005 to 2010. Am J Hypertens (2013) 1.70

The seventh edition of the UICC/AJCC staging system for nasopharyngeal carcinoma is prognostically useful for patients treated with intensity-modulated radiotherapy from an endemic area in China. Radiother Oncol (2011) 1.60

Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. Am J Pathol (2007) 1.59

Extended transsternal thymectomy for the treatment of ocular myasthenia gravis. Ann Thorac Surg (2011) 1.58

Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccines. Nature (2007) 1.51

The association of weight with the detection of airflow obstruction and inhaled treatment among patients with a clinical diagnosis of COPD. Chest (2014) 1.51

Current Science on Consumer Use of Mobile Health for Cardiovascular Disease Prevention: A Scientific Statement From the American Heart Association. Circulation (2015) 1.48

Probing intrinsic properties of a robust morphogen gradient in Drosophila. Dev Cell (2008) 1.48

The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma: analysis of the spread patterns in lymph nodes by magnetic resonance imaging. Cancer (2009) 1.45

Extension of local disease in nasopharyngeal carcinoma detected by magnetic resonance imaging: improvement of clinical target volume delineation. Int J Radiat Oncol Biol Phys (2009) 1.45

How does magnetic resonance imaging influence staging according to AJCC staging system for nasopharyngeal carcinoma compared with computed tomography? Int J Radiat Oncol Biol Phys (2008) 1.44

Secular trends of obesity prevalence in urban Chinese children from 1985 to 2010: gender disparity. PLoS One (2013) 1.43

Oxidation of sulfoxides and arsenic(III) in corrosion of nanoscale zero valent iron by oxygen: evidence against ferryl ions (Fe(IV)) as active intermediates in Fenton reaction. Environ Sci Technol (2010) 1.42

The N staging system in nasopharyngeal carcinoma with radiation therapy oncology group guidelines for lymph node levels based on magnetic resonance imaging. Clin Cancer Res (2008) 1.41

Underutilization of aspirin persists in US ambulatory care for the secondary and primary prevention of cardiovascular disease. PLoS Med (2005) 1.41

Association of INSIG2 rs9308762 with ALT level independent of BMI. J Pediatr Gastroenterol Nutr (2014) 1.40

Waist Circumference is Better Than Other Anthropometric Indices for Predicting Cardiovascular Disease Risk Factors in Chinese Children-a Cross-Sectional Study in Guangzhou. J Atheroscler Thromb (2015) 1.40

Synthetic studies of complex immunostimulants from Quillaja saponaria: synthesis of the potent clinical immunoadjuvant QS-21Aapi. J Am Chem Soc (2006) 1.39

Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol Cell Biol (2010) 1.35

Tumor detection and elimination by a targeted gallium corrole. Proc Natl Acad Sci U S A (2009) 1.34

Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma detected by magnetic resonance imaging : prognostic value and staging categories. Cancer (2008) 1.33

Progress report of a randomized trial comparing long-term survival and late toxicity of concurrent chemoradiotherapy with adjuvant chemotherapy versus radiotherapy alone in patients with stage III to IVB nasopharyngeal carcinoma from endemic regions of China. Cancer (2013) 1.33

Prognostic impact of magnetic resonance imaging-detected cranial nerve involvement in nasopharyngeal carcinoma. Cancer (2009) 1.33

Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner. J Biol Chem (2006) 1.33

Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development. Development (2008) 1.32

Homoharringtonine-based induction regimens for patients with de-novo acute myeloid leukaemia: a multicentre, open-label, randomised, controlled phase 3 trial. Lancet Oncol (2013) 1.31

Genetic relationships between resistances to Fusarium head blight and crown rot in bread wheat (Triticum aestivum L.). Theor Appl Genet (2010) 1.30

Re-evaluation of 6th edition of AJCC staging system for nasopharyngeal carcinoma and proposed improvement based on magnetic resonance imaging. Int J Radiat Oncol Biol Phys (2009) 1.29

Prognostic value of subclassification using MRI in the t4 classification nasopharyngeal carcinoma intensity-modulated radiotherapy treatment. Int J Radiat Oncol Biol Phys (2012) 1.28

NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction. Mol Cancer (2014) 1.27

DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV. Proc Natl Acad Sci U S A (2013) 1.27

National trends in asthma visits and asthma pharmacotherapy, 1978-2002. J Allergy Clin Immunol (2003) 1.26

General approach for the synthesis of 12-methoxy-substituted sarpagine indole alkaloids including (-)-12-methoxy-N(b)-methylvoachalotine, (+)-12-methoxy-N(a)-methylvellosimine, (+)-12-methoxyaffinisine, and (-)-fuchsiaefoline. J Org Chem (2006) 1.25

MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma. Cancer Lett (2012) 1.23

Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. PLoS Pathog (2013) 1.22

Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. Int J Cancer (2007) 1.21

Locoregional extension patterns of nasopharyngeal carcinoma and suggestions for clinical target volume delineation. Chin J Cancer (2012) 1.20

Oral tetra-arsenic tetra-sulfide formula versus intravenous arsenic trioxide as first-line treatment of acute promyelocytic leukemia: a multicenter randomized controlled trial. J Clin Oncol (2013) 1.19

Replicative senescence of human bone marrow and umbilical cord derived mesenchymal stem cells and their differentiation to adipocytes and osteoblasts. Mol Biol Rep (2010) 1.19

Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders. Cell Cycle (2009) 1.16

Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome. Biochemistry (2005) 1.16

Coordinated changes in dendritic arborization and synaptic strength during neural circuit development. Neuron (2009) 1.13

HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China. Int J Infect Dis (2007) 1.13

Total synthesis of (+)-batzelladine A and (-)-batzelladine D via [4 + 2]-annulation of vinyl carbodiimides with N-alkyl imines. J Am Chem Soc (2006) 1.13

Promising treatment outcomes of intensity-modulated radiation therapy for nasopharyngeal carcinoma patients with N0 disease according to the seventh edition of the AJCC staging system. BMC Cancer (2012) 1.13

Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer. PLoS One (2011) 1.12

Underdiagnosis of obesity in adults in US outpatient settings. Arch Intern Med (2009) 1.12

Design and synthesis of potent Quillaja saponin vaccine adjuvants. J Am Chem Soc (2010) 1.12

Asymmetric synthetic access to the hetisine alkaloids: total synthesis of (+)-nominine. Chemistry (2008) 1.12

Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry (2006) 1.12

Aurora kinase B modulates chromosome alignment in mouse oocytes. Mol Reprod Dev (2009) 1.12

Enantiospecific synthesis of the bridged pyrrolizidine core of asparagamine A: dipolar cycloadditions of azomethine ylides derived from the sulfonylation of vinylogous amides. Angew Chem Int Ed Engl (2002) 1.12

Synthesis of the potent immunostimulatory adjuvant QS-21A. J Am Chem Soc (2005) 1.12

Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals. Obesity (Silver Spring) (2009) 1.12

Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma. Dis Esophagus (2009) 1.12

The activity of the Drosophila morphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain. Development (2002) 1.11

A four-miRNA signature identified from genome-wide serum miRNA profiling predicts survival in patients with nasopharyngeal carcinoma. Int J Cancer (2013) 1.10

Prognostic value and staging categories of anatomic masticator space involvement in nasopharyngeal carcinoma: a study of 924 cases with MR imaging. Radiology (2010) 1.10

Activation tagging, an efficient tool for functional analysis of the rice genome. Plant Mol Biol (2008) 1.10

A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study. J Diabetes Complications (2008) 1.10

Complete coding sequences and phylogenetic analysis of porcine bocavirus. J Gen Virol (2011) 1.09

Self-efficacy, perceived benefits, and weight satisfaction discriminate among stages of change for fruit and vegetable intakes for young men and women. J Am Diet Assoc (2002) 1.08

Waist circumference distribution of Chinese school-age children and adolescents. Biomed Environ Sci (2010) 1.08

Enantioselective approach to the hetisine alkaloids. Synthesis of the 3-methyl-1-aza-tricyclo[5.2.1.0(3,8)]decane core via intramolecular dipolar cycloaddition. Org Lett (2005) 1.07

Efficient synthetic access to the hetisine C20-diterpenoid alkaloids. A concise synthesis of nominine via oxidoisoquinolinium-1,3-dipolar and dienamine-Diels-Alder cycloadditions. J Am Chem Soc (2006) 1.07

An atlas-based geometry pipeline for cardiac Hermite model construction and diffusion tensor reorientation. Med Image Anal (2012) 1.06

Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer. Expert Rev Vaccines (2011) 1.06

The Genboree Microbiome Toolset and the analysis of 16S rRNA microbial sequences. BMC Bioinformatics (2012) 1.05

Saponins from the traditional medicinal plant Momordica charantia stimulate insulin secretion in vitro. Phytomedicine (2011) 1.05

Comment on Electrolytic manipulation of persulfate reactivity by iron electrodes for TCE degradation in groundwater. Environ Sci Technol (2014) 1.05

Alpha B-crystallin is a new prognostic marker for laryngeal squamous cell carcinoma. J Exp Clin Cancer Res (2012) 1.05

Radiation-induced temporal lobe injury for nasopharyngeal carcinoma: a comparison of intensity-modulated radiotherapy and conventional two-dimensional radiotherapy. PLoS One (2013) 1.04

Dietary pattern and its association with the prevalence of obesity and related cardiometabolic risk factors among Chinese children. PLoS One (2012) 1.04

Epidemiological and clinical features of Moyamoya disease in Nanjing, China. Clin Neurol Neurosurg (2009) 1.04

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine. Angew Chem Int Ed Engl (2008) 1.04

Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells. Biochem J (2012) 1.04

Proposed lymph node staging system using the International Consensus Guidelines for lymph node levels is predictive for nasopharyngeal carcinoma patients from endemic areas treated with intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys (2012) 1.04

Nucleocytoplasmic shuttling of receptor-interacting protein 3 (RIP3): identification of novel nuclear export and import signals in RIP3. J Biol Chem (2004) 1.03