Published in Learn Mem on May 16, 2005
Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci (2008) 1.30
Developmental expression of retinoic acid receptors (RARs). Nucl Recept Signal (2009) 1.08
Mouse pharmacological models of cognitive disruption relevant to schizophrenia. Neuropharmacology (2011) 0.95
Stress during a critical postnatal period induces region-specific structural abnormalities and dysfunction of the prefrontal cortex via CRF1. Neuropsychopharmacology (2015) 0.84
Longitudinal analysis of the behavioral phenotype in a novel transgenic rat model of early stages of Alzheimer's disease. Front Behav Neurosci (2014) 0.82
Retinoic acid induces changes in electrical properties of adult neurons in a dose- and isomer-dependent manner. J Neurophysiol (2013) 0.82
9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice. PLoS Genet (2015) 0.81
Distinct roles of basal forebrain cholinergic neurons in spatial and object recognition memory. Sci Rep (2015) 0.80
Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice. Mol Psychiatry (2015) 0.79
Long-distance retinoid signaling in the zebra finch brain. PLoS One (2014) 0.77
EPA/DHA and Vitamin A Supplementation Improves Spatial Memory and Alleviates the Age-related Decrease in Hippocampal RXRγ and Kinase Expression in Rats. Front Aging Neurosci (2016) 0.75
The role of retinoic acid in the formation and modulation of invertebrate central synapses. J Neurophysiol (2016) 0.75
Cav1.2 channels mediate persistent chronic stress-induced behavioral deficits that are associated with prefrontal cortex activation of the p25/Cdk5-glucocorticoid receptor pathway. Neurobiol Stress (2017) 0.75
Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II. PLoS One (2017) 0.75
Antiamnesic Effects of a Hydroethanolic Extract of Crinum macowanii on Scopolamine-Induced Memory Impairment in Mice. J Neurodegener Dis (2015) 0.75
The RXR heterodimers and orphan receptors. Cell (1995) 12.33
A decade of molecular biology of retinoic acid receptors. FASEB J (1996) 9.70
A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. Behav Brain Res (1988) 7.29
Recognition memory: what are the roles of the perirhinal cortex and hippocampus? Nat Rev Neurosci (2001) 7.25
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
The prefrontal cortex--an update: time is of the essence. Neuron (2001) 5.09
A cortical-hippocampal system for declarative memory. Nat Rev Neurosci (2000) 4.95
Impaired recognition memory in rats after damage to the hippocampus. J Neurosci (2000) 4.07
Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat Neurosci (1999) 3.85
Central cholinergic systems and cognition. Annu Rev Psychol (1997) 3.80
Delay-dependent impairment of a matching-to-place task with chronic and intrahippocampal infusion of the NMDA-antagonist D-AP5. Hippocampus (1999) 3.55
Do rats have a prefrontal cortex? Behav Brain Res (2003) 3.38
Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe. J Neurosci (2004) 2.76
Involvement of the prelimbic-infralimbic areas of the rodent prefrontal cortex in behavioral flexibility for place and response learning. J Neurosci (1999) 2.45
Spatial memory dissociations in mice lacking GluR1. Nat Neurosci (2002) 2.39
Memory in monkeys severely impaired by combined but not by separate removal of amygdala and hippocampus. Nature (1978) 2.39
Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty. Nat Neurosci (2003) 2.38
On the delay-dependent involvement of the hippocampus in object recognition memory. Neurobiol Learn Mem (2004) 2.37
Perspectives on object-recognition memory following hippocampal damage: lessons from studies in rats. Behav Brain Res (2001) 2.35
Spontaneous object recognition and object location memory in rats: the effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix. Exp Brain Res (1997) 2.34
Novelty and familiarity activations in PET studies of memory encoding and retrieval. Cereb Cortex (1996) 2.22
Functional organization of the extrinsic and intrinsic circuitry of the parahippocampal region. Prog Neurobiol (1989) 2.20
Segregation of working memory functions within the dorsolateral prefrontal cortex. Exp Brain Res (2000) 2.17
Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction. Psychopharmacology (Berl) (2004) 2.06
Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. Proc Natl Acad Sci U S A (1998) 2.00
Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development. Development (1997) 1.94
Glutamate, dopamine, and schizophrenia: from pathophysiology to treatment. Ann N Y Acad Sci (2003) 1.92
Opposite relationship of hippocampal and rhinal cortex damage to delayed nonmatching-to-sample deficits in monkeys. Hippocampus (2001) 1.76
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav Genet (1999) 1.74
Cholinergic neurotransmission is essential for perirhinal cortical plasticity and recognition memory. Neuron (2003) 1.67
Perirhinal and postrhinal cortices of the rat: a review of the neuroanatomical literature and comparison with findings from the monkey brain. Hippocampus (1995) 1.66
Transitive inference in schizophrenia: impairments in relational memory organization. Schizophr Res (2004) 1.64
Plasticity at hippocampal to prefrontal cortex synapses: dual roles in working memory and consolidation. Hippocampus (2000) 1.61
Time-dependent relationship between the dorsal hippocampus and the prefrontal cortex in spatial memory. J Neurosci (2003) 1.59
An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron (1998) 1.58
RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable. Proc Natl Acad Sci U S A (1996) 1.52
Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat. Behav Brain Res (2000) 1.49
Differential expression of retinoid receptors in the adult mouse central nervous system. Neuroscience (1999) 1.48
Role of the retinoic acid receptor beta (RARbeta) during mouse development. Int J Dev Biol (1997) 1.41
Impaired locomotion and dopamine signaling in retinoid receptor mutant mice. Science (1998) 1.39
Fos imaging reveals differential patterns of hippocampal and parahippocampal subfield activation in rats in response to different spatial memory tests. J Neurosci (2000) 1.39
Role of retinoids in the CNS: differential expression of retinoid binding proteins and receptors and evidence for presence of retinoic acid. Eur J Neurosci (1999) 1.38
Involvement of rodent prefrontal cortex subregions in strategy switching. Behav Neurosci (1999) 1.37
Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat. Brain Res Bull (1997) 1.31
A member of the RXR nuclear receptor family is expressed in neural-crest-derived cells of the developing chick peripheral nervous system. Development (1991) 1.26
The anatomical relationships of the prefrontal cortex with limbic structures and the basal ganglia. J Psychopharmacol (1997) 1.26
Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family. Proc Natl Acad Sci U S A (1997) 1.25
Disruption of the retinoid signalling pathway causes a deposition of amyloid beta in the adult rat brain. Eur J Neurosci (2004) 1.25
Cholinergic modulation of visual attention and working memory: dissociable effects of basal forebrain 192-IgG-saporin lesions and intraprefrontal infusions of scopolamine. Learn Mem (2004) 1.24
Vitamin A deficiency produces spatial learning and memory impairment in rats. Neuroscience (2002) 1.24
Recognition memory in rats--II. Neuroanatomical substrates. Prog Neurobiol (1998) 1.24
Retrograde and anterograde object recognition in rats with hippocampal lesions. Hippocampus (2003) 1.23
Alleviation of a selective age-related relational memory deficit in mice by pharmacologically induced normalization of brain retinoid signaling. J Neurosci (2001) 1.20
Effects of muscarinic blockade in perirhinal cortex during visual recognition. Proc Natl Acad Sci U S A (1997) 1.19
Three independent lines of evidence suggest retinoids as causal to schizophrenia. Proc Natl Acad Sci U S A (1998) 1.15
Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells. Genes Dev (2003) 1.13
Vitamin A deficiency and relational memory deficit in adult mice: relationships with changes in brain retinoid signalling. Behav Brain Res (2003) 1.13
Novelty assessment in the brain and long-term memory encoding. Psychon Bull Rev (1995) 1.08
The "psychic" neuron of the cerebral cortex. Ann N Y Acad Sci (1999) 1.08
Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter. J Neurochem (1995) 1.07
Dopamine antagonism in a novel-object recognition and a novel-object place conditioning preparation with rats. Behav Brain Res (1999) 1.01
Infralimbic kappa opioid and muscarinic M1 receptor interactions in the concurrent modulation of anxiety and memory. Psychopharmacology (Berl) (2002) 1.00
Differential effects of selective immunotoxic lesions of medial septal cholinergic cells on spatial working and reference memory. Behav Neurosci (1996) 0.99
The effects of prelimbic and infralimbic lesions on working memory for visual objects in rats. Neurobiol Learn Mem (2002) 0.93
The effect of excitotoxic lesions centered on the hippocampus or perirhinal cortex in object recognition and spatial memory tasks. Behav Neurosci (2001) 0.91
A comparison of normal old rats and young adult rats with lesions to the hippocampus or prefrontal cortex on a test of matching-to-sample. Neuropsychologia (1992) 0.90
The effects of muscarinic cholinergic receptor blockade in the rat anterior cingulate and Prelimbic/Infralimbic cortices on spatial working memory. Neurobiol Learn Mem (1998) 0.90
The performance of amnesic subjects on tests of delayed matching-to-sample and delayed matching-to-position. Neuropsychologia (1995) 0.89
Impaired extrapyramidal function caused by the targeted disruption of retinoid X receptor RXRgamma1 isoform. Genes Cells (1999) 0.79
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell (2006) 19.16
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis (2004) 6.83
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell (2007) 4.71
Jarid2 and PRC2, partners in regulating gene expression. Genes Dev (2010) 4.65
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature (2008) 4.60
A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell (2007) 4.59
SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell (2002) 4.31
The European dimension for the mouse genome mutagenesis program. Nat Genet (2004) 3.84
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature (2003) 3.49
Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (2004) 3.46
Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis. Annu Rev Pharmacol Toxicol (2006) 3.39
Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs. Cell (2013) 3.34
Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland. Proc Natl Acad Sci U S A (2006) 3.32
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity (2008) 3.25
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse. EMBO J (2003) 2.94
Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron (2002) 2.93
Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network. J Exp Med (2009) 2.77
NSD1 is essential for early post-implantation development and has a catalytically active SET domain. EMBO J (2003) 2.72
EuroPhenome: a repository for high-throughput mouse phenotyping data. Nucleic Acids Res (2009) 2.72
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Mol Cell (2002) 2.69
A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse. Nat Biotechnol (2003) 2.65
Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis. Proc Natl Acad Sci U S A (2006) 2.60
Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors. Nat Med (2012) 2.59
Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity (2003) 2.56
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes Dev (2004) 2.49
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A (2004) 2.46
Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development. Nat Genet (2002) 2.45
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell (2012) 2.45
PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Mol Cell (2005) 2.44
A G-protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis. J Neurosci (2006) 2.40
The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP. Mol Cell Biol (2002) 2.40
Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology (2007) 2.40
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes. Cell Metab (2006) 2.26
International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacol Rev (2006) 2.22
Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell (2011) 2.22
Efficient, inducible Cre-recombinase activation in vascular endothelium. Genesis (2008) 2.21
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Dev Biol (2005) 2.13
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment. Proc Natl Acad Sci U S A (2003) 2.07
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A (2005) 2.07
Function of retinoic acid receptors during embryonic development. Nucl Recept Signal (2009) 2.06
Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury. Circ Res (2002) 2.05
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biol (2013) 2.04
International Union of Pharmacology. LX. Retinoic acid receptors. Pharmacol Rev (2006) 2.04
Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy. Proc Natl Acad Sci U S A (2008) 1.94
Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin. Proc Natl Acad Sci U S A (2005) 1.92
Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. J Neurosci (2009) 1.89
Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol. Proc Natl Acad Sci U S A (2003) 1.87
Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells. Mol Cell Neurosci (2003) 1.84
Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells. Development (2005) 1.83
Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice. J Clin Invest (2011) 1.81
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A (2008) 1.80
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiol Genomics (2008) 1.76
Retinoic acid metabolism and signaling pathways in the adult and developing mouse testis. Endocrinology (2005) 1.76
Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation. Genes Dev (2004) 1.76
RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. J Exp Med (2006) 1.72
Suppressive function of androgen receptor in bone resorption. Proc Natl Acad Sci U S A (2003) 1.72
Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun (2011) 1.69
Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha. Nat Genet (2007) 1.68
HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis. Proc Natl Acad Sci U S A (2013) 1.67
Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech Dev (2002) 1.67
Retinoic acid controls the bilateral symmetry of somite formation in the mouse embryo. Science (2005) 1.66
Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma. Proc Natl Acad Sci U S A (2009) 1.63
T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha. J Biol Chem (2003) 1.62
Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouse. Genesis (2004) 1.61
Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene. Genes Dev (2006) 1.60
Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction. J Cell Sci (2002) 1.59
Prevention of skin flap necrosis by estradiol involves reperfusion of a protected vascular network. Circ Res (2008) 1.57
Mouse functional genomics requires standardization of mouse handling and housing conditions. Mamm Genome (2004) 1.56
Female mice lacking estrogen receptor beta display prolonged ventricular repolarization and reduced ventricular automaticity after myocardial infarction. Circulation (2005) 1.55
STRA8-deficient spermatocytes initiate, but fail to complete, meiosis and undergo premature chromosome condensation. J Cell Sci (2008) 1.54
In vivo activation of PPAR target genes by RXR homodimers. EMBO J (2004) 1.53
Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest (2015) 1.53
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol (2006) 1.52
Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse. Development (2002) 1.52
Brain masculinization requires androgen receptor function. Proc Natl Acad Sci U S A (2004) 1.51
Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant. Proc Natl Acad Sci U S A (2008) 1.51
Induction of thymic stromal lymphopoietin expression in keratinocytes is necessary for generating an atopic dermatitis upon application of the active vitamin D3 analogue MC903 on mouse skin. J Invest Dermatol (2008) 1.48
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure. Proc Natl Acad Sci U S A (2007) 1.46
Premature ovarian failure in androgen receptor-deficient mice. Proc Natl Acad Sci U S A (2005) 1.44
Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis. Nat Immunol (2013) 1.42
SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity. Mol Biol Cell (2009) 1.41
The role of estrogen receptor α and β in regulating vascular smooth muscle cell proliferation is based on sex. J Surg Res (2011) 1.41
Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver. J Biol Chem (2004) 1.40
Brg1 is required for murine neural stem cell maintenance and gliogenesis. Dev Biol (2005) 1.38
Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse. Genesis (2009) 1.37
Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled. EMBO J (2002) 1.36
Temporal regulation of Cre recombinase activity in neural stem cells. Genesis (2006) 1.36
Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development (2010) 1.35
Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha. EMBO J (2002) 1.35
The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system. Development (2003) 1.34
Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons. J Neurochem (2007) 1.34
Regenerated luminal epithelial cells are derived from preexisting luminal epithelial cells in adult mouse prostate. Mol Endocrinol (2011) 1.32
Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse. Genesis (2005) 1.32
Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells. EMBO J (2006) 1.31
Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. Mech Dev (2002) 1.31
Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice. Proc Natl Acad Sci U S A (2003) 1.30