Published in Curr Opin Cell Biol on April 22, 2008
Nucleosome positioning as a determinant of exon recognition. Nat Struct Mol Biol (2009) 5.14
Nucleosomes are well positioned in exons and carry characteristic histone modifications. Genome Res (2009) 3.95
The splicing factor SC35 has an active role in transcriptional elongation. Nat Struct Mol Biol (2008) 3.86
Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation. Nucleic Acids Res (2009) 3.44
"Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions. Mol Cell (2009) 3.28
SR proteins in vertical integration of gene expression from transcription to RNA processing to translation. Mol Cell (2009) 2.73
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. PLoS Biol (2011) 2.58
The pathobiology of splicing. J Pathol (2010) 2.52
Splicing-dependent RNA polymerase pausing in yeast. Mol Cell (2010) 2.49
Dynamic integration of splicing within gene regulatory pathways. Cell (2013) 2.25
Nuclear neighborhoods and gene expression. Curr Opin Genet Dev (2009) 2.21
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J (2010) 2.11
Assembly of ribosomes and spliceosomes: complex ribonucleoprotein machines. Curr Opin Cell Biol (2009) 1.96
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol Cell (2012) 1.83
Regulation of splicing by SR proteins and SR protein-specific kinases. Chromosoma (2013) 1.53
RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. Hum Mol Genet (2012) 1.51
The eIF3 interactome reveals the translasome, a supercomplex linking protein synthesis and degradation machineries. Mol Cell (2009) 1.45
A role for TREX components in the release of spliced mRNA from nuclear speckle domains. Nat Commun (2010) 1.43
Neurodegeneration the RNA way. Prog Neurobiol (2011) 1.43
A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint. Genes Dev (2009) 1.42
The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex. Genes Dev (2011) 1.37
The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathway. Mol Cell (2009) 1.35
Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner. Proc Natl Acad Sci U S A (2011) 1.30
Antagonistic factors control the unproductive splicing of SC35 terminal intron. Nucleic Acids Res (2009) 1.28
Estimation of alternative splicing variability in human populations. Genome Res (2011) 1.27
Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation. J Cell Biol (2011) 1.25
The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1. Genes Dev (2011) 1.21
Genetic variants contribute to gene expression variability in humans. Genetics (2012) 1.20
Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts. RNA (2011) 1.14
Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency. J Virol (2011) 1.10
To polyadenylate or to deadenylate: that is the question. Cell Cycle (2010) 1.09
Recognition of polyadenosine RNA by the zinc finger domain of nuclear poly(A) RNA-binding protein 2 (Nab2) is required for correct mRNA 3'-end formation. J Biol Chem (2010) 1.04
Cyclin K goes with Cdk12 and Cdk13. Cell Div (2012) 1.03
Cotranscriptional effect of a premature termination codon revealed by live-cell imaging. RNA (2011) 1.02
Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution. Proc Natl Acad Sci U S A (2009) 1.01
Subnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or accumulation in SC35 foci. Cell Cycle (2009) 1.00
Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1. Mol Cell Biochem (2010) 1.00
Two Prp19-like U-box proteins in the MOS4-associated complex play redundant roles in plant innate immunity. PLoS Pathog (2009) 0.99
The Role of Protein Arginine Methylation in mRNP Dynamics. Mol Biol Int (2011) 0.98
H2B ubiquitylation controls the formation of export-competent mRNP. Mol Cell (2012) 0.97
Viral factors reveal a role for REF/Aly in nuclear RNA stability. Mol Cell Biol (2012) 0.97
SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles. Mol Biol Cell (2012) 0.97
Differential patterns of intronic and exonic DNA regions with respect to RNA polymerase II occupancy, nucleosome density and H3K36me3 marking in fission yeast. Genome Biol (2011) 0.94
Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity. Virology (2011) 0.94
A model in vitro system for co-transcriptional splicing. Nucleic Acids Res (2010) 0.94
Non-polyadenylated transcription in embryonic stem cells reveals novel non-coding RNA related to pluripotency and differentiation. Nucleic Acids Res (2013) 0.94
Combinations of histone modifications mark exon inclusion levels. PLoS One (2012) 0.93
The Carboxyl-terminal Domain of RNA Polymerase II Is Not Sufficient to Enhance the Efficiency of Pre-mRNA Capping or Splicing in the Context of a Different Polymerase. J Biol Chem (2009) 0.92
PPS, a large multidomain protein, functions with sex-lethal to regulate alternative splicing in Drosophila. PLoS Genet (2010) 0.91
Single-molecule studies of transcription: from one RNA polymerase at a time to the gene expression profile of a cell. J Mol Biol (2011) 0.91
A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR. J Biol Chem (2009) 0.90
Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II. J Biol Chem (2011) 0.89
Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription. Nucleic Acids Res (2011) 0.88
An integrated regulatory network reveals pervasive cross-regulation among transcription and splicing factors. PLoS Comput Biol (2012) 0.88
RNA polymerase II progression through H3K27me3-enriched gene bodies requires JMJD3 histone demethylase. Mol Biol Cell (2012) 0.87
Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development. Mol Cell Biol (2011) 0.86
Evidence for a DNA-Based Mechanism of Intron-Mediated Enhancement. Front Plant Sci (2011) 0.85
Selective recruitment of nuclear factors to productively replicating herpes simplex virus genomes. PLoS Pathog (2015) 0.85
Retention of spliceosomal components along ligated exons ensures efficient removal of multiple introns. RNA (2010) 0.84
The Ess1 prolyl isomerase: traffic cop of the RNA polymerase II transcription cycle. Biochim Biophys Acta (2014) 0.84
RNA Polymerase II Elongation at the Crossroads of Transcription and Alternative Splicing. Genet Res Int (2011) 0.84
Intron retention in the alternatively spliced region of RON results from weak 3' splice site recognition. PLoS One (2013) 0.83
Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing. RNA (2011) 0.82
The SR protein B52/SRp55 is required for DNA topoisomerase I recruitment to chromatin, mRNA release and transcription shutdown. PLoS Genet (2010) 0.81
SAM68: Signal Transduction and RNA Metabolism in Human Cancer. Biomed Res Int (2015) 0.81
Regulation of alternative splicing within the supraspliceosome. J Struct Biol (2011) 0.81
RSR-2, the Caenorhabditis elegans ortholog of human spliceosomal component SRm300/SRRM2, regulates development by influencing the transcriptional machinery. PLoS Genet (2013) 0.81
Modeling exon expression using histone modifications. PLoS One (2013) 0.80
The new nucleoporin: regulator of transcriptional repression and beyond. Nucleus (2012) 0.80
Control of V(D)J Recombination through Transcriptional Elongation and Changes in Locus Chromatin Structure and Nuclear Organization. Genet Res Int (2011) 0.80
Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Mol Cell (2016) 0.80
Insights into mRNP biogenesis provided by new genetic interactions among export and transcription factors. BMC Genet (2012) 0.79
Systems analysis of the prostate tumor suppressor NKX3.1 supports roles in DNA repair and luminal cell differentiation. F1000Res (2014) 0.79
Nuclear ataxias. Cold Spring Harb Perspect Biol (2010) 0.79
Algorithm to identify frequent coupled modules from two-layered network series: application to study transcription and splicing coupling. J Comput Biol (2012) 0.79
mRNA quality control goes transcriptional. Biochem Soc Trans (2013) 0.79
smFRET studies of the 'encounter' complexes and subsequent intermediate states that regulate the selectivity of ligand binding. FEBS Lett (2014) 0.78
Introduction to cotranscriptional RNA splicing. Methods Mol Biol (2014) 0.78
Promoter-Dependent Translation Controlled by p54nrb and hnRNPM during Myoblast Differentiation. PLoS One (2015) 0.78
The mediator couples transcription and splicing. Mol Cell (2012) 0.78
A network of RNA and protein interactions in Fronto Temporal Dementia. Front Mol Neurosci (2015) 0.77
Tracking intron removal in real time. Dev Cell (2011) 0.77
Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy. Nucleic Acids Res (2014) 0.77
TINTIN, at the interface of chromatin, transcription elongation, and mRNA processing. RNA Biol (2015) 0.77
Knockdown of menin affects pre-mRNA processing and promoter fidelity at the interferon-gamma inducible IRF1 gene. Epigenetics Chromatin (2012) 0.75
Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells. Genet Res Int (2011) 0.75
Roles of Sumoylation in mRNA Processing and Metabolism. Adv Exp Med Biol (2017) 0.75
Dangerous play--splitting the message may leave you empty handed. Nat Struct Mol Biol (2009) 0.75
Premature Termination Codons Are Recognized in the Nucleus in A Reading-Frame Dependent Manner. Cell Discov (2015) 0.75
DNA-Encoded Chromatin Structural Intron Boundary Signals Identify Conserved Genes with Common Function. Int J Genomics (2015) 0.75
The C-Terminal SynMuv/DdDUF926 Domain Regulates the Function of the N-Terminal Domain of DdNKAP. PLoS One (2016) 0.75
An extensive network of coupling among gene expression machines. Nature (2002) 11.84
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev (2000) 10.64
Integrating mRNA processing with transcription. Cell (2002) 9.74
Breaking barriers to transcription elongation. Nat Rev Mol Cell Biol (2006) 8.18
Phosphorylation and functions of the RNA polymerase II CTD. Genes Dev (2006) 7.44
TREX is a conserved complex coupling transcription with messenger RNA export. Nature (2002) 6.53
A slow RNA polymerase II affects alternative splicing in vivo. Mol Cell (2003) 5.82
Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol Cell (2007) 5.78
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors. Curr Opin Cell Biol (2005) 5.14
Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell (2005) 4.91
Multiple links between transcription and splicing. RNA (2004) 4.90
RNA polymerase II is an essential mRNA polyadenylation factor. Nature (1998) 4.87
Dynamic association of capping enzymes with transcribing RNA polymerase II. Genes Dev (2000) 4.47
The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins. Proc Natl Acad Sci U S A (1996) 4.16
Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature (2001) 3.94
Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II. Mol Cell (2002) 3.39
Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA. Nature (1997) 3.39
The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model. Genes Dev (2006) 3.36
RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes. Nat Struct Mol Biol (2007) 3.36
Gene loops juxtapose promoters and terminators in yeast. Nat Genet (2004) 3.33
RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts. Nature (2001) 3.29
Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells. Nat Struct Mol Biol (2006) 3.21
Recruitment of the human TREX complex to mRNA during splicing. Genes Dev (2005) 3.13
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell (1999) 3.10
SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. Mol Cell (2007) 3.04
Phosphorylated RNA polymerase II stimulates pre-mRNA splicing. Genes Dev (1999) 3.00
The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing. Mol Cell (2007) 2.94
Stimulatory effect of splicing factors on transcriptional elongation. Nature (2002) 2.76
Coupling transcription, splicing and mRNA export. Curr Opin Cell Biol (2003) 2.54
Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns. PLoS Biol (2006) 2.51
Exon tethering in transcription by RNA polymerase II. Mol Cell (2006) 2.47
Connections between mRNA 3' end processing and transcription termination. Curr Opin Cell Biol (2005) 2.46
Promoter usage and alternative splicing. Curr Opin Cell Biol (2005) 2.44
Strange bedfellows: polyadenylation factors at the promoter. Genes Dev (2003) 2.41
Perturbation of transcription elongation influences the fidelity of internal exon inclusion in Saccharomyces cerevisiae. RNA (2003) 2.36
The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. Genes Dev (2007) 2.36
Chromatin, transcript elongation and alternative splicing. Nat Struct Mol Biol (2006) 2.35
Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II. Mol Cell (1999) 2.29
Cotranscriptional processes and their influence on genome stability. Genes Dev (2006) 2.23
The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem (2000) 2.07
p54(nrb) associates with the 5' splice site within large transcription/splicing complexes. EMBO J (2004) 2.06
Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol (2007) 2.04
Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II. Proc Natl Acad Sci U S A (2004) 2.01
Functional coupling of RNAP II transcription to spliceosome assembly. Genes Dev (2006) 1.98
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J (2004) 1.88
Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination. Mol Cell (2001) 1.85
P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo. Mol Cell Biol (2007) 1.81
Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD. RNA (2002) 1.71
Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome. Biochemistry (2004) 1.68
A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. Genes Dev (2005) 1.66
Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell (2005) 1.66
Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivo. Mol Cell Biol (2005) 1.64
In vivo kinetics of mRNA splicing and transport in mammalian cells. Mol Cell Biol (2002) 1.63
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Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals. Mol Cell (2008) 1.50
In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants. Genes Dev (2006) 1.49
Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors. J Biol Chem (2001) 1.35
A function of yeast mRNA cap methyltransferase, Abd1, in transcription by RNA polymerase II. Mol Cell (2004) 1.35
ATP can be dispensable for prespliceosome formation in yeast. Genes Dev (2000) 1.34
Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors. RNA (2003) 1.31
Differential recruitment of the splicing machinery during transcription predicts genome-wide patterns of mRNA splicing. Mol Cell (2006) 1.27
Analyzing mechanisms of alternative pre-mRNA splicing using in vitro splicing assays. Methods (2005) 1.18
FF domains of CA150 bind transcription and splicing factors through multiple weak interactions. Mol Cell Biol (2004) 1.09
Transcription initiation by RNA polymerase II is inhibited by S-adenosylhomocysteine. Proc Natl Acad Sci U S A (1982) 1.07
The yeast capping enzyme represses RNA polymerase II transcription. Mol Cell (2002) 1.07
Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription. Genome Res (2006) 1.06
mRNA capping enzyme activity is coupled to an early transcription elongation. Mol Cell Biol (2004) 1.02
Human transcription elongation factor CA150 localizes to splicing factor-rich nuclear speckles and assembles transcription and splicing components into complexes through its amino and carboxyl regions. Mol Cell Biol (2006) 1.02
Concurrent splicing and transcription are not sufficient to enhance splicing efficiency. RNA (2007) 0.99
In vitro coupled transcription splicing. Methods (2005) 0.99
The RNA binding protein RNPS1 alleviates ASF/SF2 depletion-induced genomic instability. RNA (2007) 0.98
Determination of tag density required for digital transcriptome analysis: application to an androgen-sensitive prostate cancer model. Proc Natl Acad Sci U S A (2008) 11.86
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell (2012) 6.80
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nat Struct Mol Biol (2009) 6.37
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature (2011) 6.25
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature (2011) 6.10
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell (2009) 5.74
Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol Cell (2009) 4.71
Concern Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci U S A (2008) 4.31
A versatile assay for high-throughput gene expression profiling on universal array matrices. Genome Res (2004) 4.19
Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature (2007) 4.12
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell (2005) 3.96
Profiling alternative splicing on fiber-optic arrays. Nat Biotechnol (2002) 3.94
The splicing factor SC35 has an active role in transcriptional elongation. Nat Struct Mol Biol (2008) 3.86
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am J Physiol Endocrinol Metab (2006) 3.71
MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction. J Biol Chem (2009) 3.34
A selective filter for cytoplasmic transport at the axon initial segment. Cell (2009) 3.09
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proc Natl Acad Sci U S A (2013) 2.95
Icotinib versus gefitinib in previously treated advanced non-small-cell lung cancer (ICOGEN): a randomised, double-blind phase 3 non-inferiority trial. Lancet Oncol (2013) 2.94
SR proteins in vertical integration of gene expression from transcription to RNA processing to translation. Mol Cell (2009) 2.73
Timing of plant immune responses by a central circadian regulator. Nature (2011) 2.60
Pre-mRNA splicing: where and when in the nucleus. Trends Cell Biol (2011) 2.54
Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism. Science (2009) 2.43
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell (2013) 2.43
A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1. Mol Cell (2008) 2.29
Mortality increases after massive exchange transfusion with older stored blood in canines with experimental pneumonia. Blood (2012) 2.22
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet (2012) 2.17
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A (2007) 2.17
SR proteins and related factors in alternative splicing. Adv Exp Med Biol (2007) 2.12
Two-dimensional transcriptome profiling: identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens. Cancer Res (2006) 2.11
Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2. Mol Cell (2005) 2.11
Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol (2007) 2.04
NMDA receptors in dopaminergic neurons are crucial for habit learning. Neuron (2011) 2.02
Systematic discovery of Rab GTPases with synaptic functions in Drosophila. Curr Biol (2011) 1.99
A Doppler transient model based on the laplace wavelet and spectrum correlation assessment for locomotive bearing fault diagnosis. Sensors (Basel) (2013) 1.97
Environmental chemical exposures and human epigenetics. Int J Epidemiol (2011) 1.97
SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase. Cell (2013) 1.97
Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation (2007) 1.88
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J (2004) 1.88
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol Cell (2012) 1.83
Integrated catalytic conversion of gamma-valerolactone to liquid alkenes for transportation fuels. Science (2010) 1.83
Homologous recombination as an evolutionary force in the avian influenza A virus. Mol Biol Evol (2008) 1.79
Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling. Mol Endocrinol (2010) 1.77
A synthetic precedent for the [FeIV2(mu-O)2] diamond core proposed for methane monooxygenase intermediate Q. Proc Natl Acad Sci U S A (2007) 1.76
Processive phosphorylation of alternative splicing factor/splicing factor 2. Proc Natl Acad Sci U S A (2003) 1.75
A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity. Plant Cell (2006) 1.71
Atorvastatin attenuates the production of IL-1β, IL-6, and TNF-α in the hippocampus of an amyloid β1-42-induced rat model of Alzheimer's disease. Clin Interv Aging (2013) 1.69
Edge-based scoring and searching method for identifying condition-responsive protein-protein interaction sub-network. Bioinformatics (2007) 1.69
5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription. Nat Struct Mol Biol (2012) 1.67
Click chemistry, a powerful tool for pharmaceutical sciences. Pharm Res (2008) 1.67
Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia. Blood (2013) 1.66
Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes Dev (2009) 1.65
Protein identification using customized protein sequence databases derived from RNA-Seq data. J Proteome Res (2011) 1.62
Corin overexpression improves cardiac function, heart failure, and survival in mice with dilated cardiomyopathy. Hypertension (2012) 1.60
Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential. Oncogene (2003) 1.59
Genome-wide analysis reveals SR protein cooperation and competition in regulated splicing. Mol Cell (2013) 1.56
The effects of iodine on intelligence in children: a meta-analysis of studies conducted in China. Asia Pac J Clin Nutr (2005) 1.53
Regulation of splicing by SR proteins and SR protein-specific kinases. Chromosoma (2013) 1.53
SON controls cell-cycle progression by coordinated regulation of RNA splicing. Mol Cell (2011) 1.52
Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation. Mol Cell (2005) 1.51
Gaining confidence in biological interpretation of the microarray data: the functional consistence of the significant GO categories. Bioinformatics (2007) 1.50
Apparently low reproducibility of true differential expression discoveries in microarray studies. Bioinformatics (2008) 1.48
Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell (2013) 1.47
Megator, an essential coiled-coil protein that localizes to the putative spindle matrix during mitosis in Drosophila. Mol Biol Cell (2004) 1.47
Saturated fatty acid-mediated endoplasmic reticulum stress and apoptosis are augmented by trans-10, cis-12-conjugated linoleic acid in liver cells. Mol Cell Biochem (2007) 1.47
PLD1-dependent PKCgamma activation downstream to Src is essential for the development of pathologic retinal neovascularization. Blood (2010) 1.46
An essential role for SRC-activated STAT-3 in 14,15-EET-induced VEGF expression and angiogenesis. Blood (2008) 1.46
Arthroscopic-assisted reduction and percutaneous cannulated screw fixation for Ideberg type III glenoid fractures: a minimum 2-year follow-up of 18 cases. Am J Sports Med (2011) 1.45
Photosensitizers containing the 1,8-naphthyridyl moiety and their use in dye-sensitized solar cells. Inorg Chem (2006) 1.45
Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity. J Biol Chem (2012) 1.45
Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro. Proc Natl Acad Sci U S A (2002) 1.45
Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death. Am J Physiol Endocrinol Metab (2010) 1.44
Observation and measurements of long thoracic nerve: a cadaver study and clinical consideration. Surg Radiol Anat (2008) 1.43
Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis. BMC Genomics (2008) 1.43
Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. J Biol Chem (2005) 1.43
Regulated cellular partitioning of SR protein-specific kinases in mammalian cells. Mol Biol Cell (2005) 1.42
Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly. Proc Natl Acad Sci U S A (2011) 1.42
Effect of 5-aza-2'-deoxycytidine on methylation of the putative imprinted control region of H19 during the in vitro development of vitrified bovine two-cell embryos. Fertil Steril (2012) 1.41
Ballistic resistance of honeycomb sandwich panels under in-plane high-velocity impact. ScientificWorldJournal (2013) 1.39
Profiling alternatively spliced mRNA isoforms for prostate cancer classification. BMC Bioinformatics (2006) 1.39
GO-2D: identifying 2-dimensional cellular-localized functional modules in Gene Ontology. BMC Genomics (2007) 1.39
A dual function of V0-ATPase a1 provides an endolysosomal degradation mechanism in Drosophila melanogaster photoreceptors. J Cell Biol (2010) 1.38
Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet (2012) 1.37
A multiplex RNA-seq strategy to profile poly(A+) RNA: application to analysis of transcription response and 3' end formation. Genomics (2011) 1.37
Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. Mol Cell Biochem (2009) 1.35
Classification of gluteal muscle contracture in children and outcome of different treatments. BMC Musculoskelet Disord (2009) 1.32
Efficacy and safety of bevacizumab plus chemotherapy in Chinese patients with metastatic colorectal cancer: a randomized phase III ARTIST trial. Chin J Cancer (2011) 1.32
Microrna-124 targets flotillin-1 to regulate proliferation and migration in breast cancer. Mol Cancer (2013) 1.30
Evaluating reproducibility of differential expression discoveries in microarray studies by considering correlated molecular changes. Bioinformatics (2009) 1.29
Chromator, a novel and essential chromodomain protein interacts directly with the putative spindle matrix protein skeletor. J Cell Biochem (2004) 1.29
Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy. J Cell Biochem (2007) 1.28
Characteristics and regulatory elements defining constitutive splicing and different modes of alternative splicing in human and mouse. RNA (2005) 1.28
Retracted Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell (2008) 1.27
Nanowire-haired inorganic membranes with superhydrophilicity and underwater ultralow adhesive superoleophobicity for high-efficiency oil/water separation. Adv Mater (2013) 1.26
MicroRNA-224 is upregulated in HepG2 cells and involved in cellular migration and invasion. J Gastroenterol Hepatol (2009) 1.24
Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. J Cell Biol (2012) 1.24
GhZFP1, a novel CCCH-type zinc finger protein from cotton, enhances salt stress tolerance and fungal disease resistance in transgenic tobacco by interacting with GZIRD21A and GZIPR5. New Phytol (2009) 1.23
Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage. Mol Cell (2005) 1.22