Published in J Biol Chem on May 18, 2005
Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state. J Bacteriol (2008) 2.60
SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis. Antimicrob Agents Chemother (2012) 2.41
Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane. Nat Chem Biol (2012) 2.40
Trehalose-recycling ABC transporter LpqY-SugA-SugB-SugC is essential for virulence of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2010) 1.42
Targeting the formation of the cell wall core of M. tuberculosis. Infect Disord Drug Targets (2007) 1.33
Last step in the conversion of trehalose to glycogen: a mycobacterial enzyme that transfers maltose from maltose 1-phosphate to glycogen. J Biol Chem (2010) 1.17
Control of cell wall assembly by a histone-like protein in Mycobacteria. J Bacteriol (2007) 0.98
Structure, composition and metagenomic profile of soil microbiomes associated to agricultural land use and tillage systems in Argentine Pampas. PLoS One (2014) 0.96
O-mycoloylated proteins from Corynebacterium: an unprecedented post-translational modification in bacteria. J Biol Chem (2010) 0.94
Mycobacterial outer membrane is a lipid bilayer and the inner membrane is unusually rich in diacyl phosphatidylinositol dimannosides. Proc Natl Acad Sci U S A (2014) 0.93
Osmolality, temperature, and membrane lipid composition modulate the activity of betaine transporter BetP in Corynebacterium glutamicum. J Bacteriol (2007) 0.90
Biochemical disclosure of the mycolate outer membrane of Corynebacterium glutamicum. J Bacteriol (2011) 0.89
Reconstitution experiments and gene deletions reveal the existence of two-component major cell wall channels in the genus Corynebacterium. J Bacteriol (2009) 0.89
Cell envelope of corynebacteria: structure and influence on pathogenicity. ISRN Microbiol (2013) 0.88
Partial redundancy in the synthesis of the D-arabinose incorporated in the cell wall arabinan of Corynebacterineae. Microbiology (2008) 0.85
Functionality and prevalence of trehalose-based oligosaccharides as novel compatible solutes in ascospores of Neosartorya fischeri (Aspergillus fischeri) and other fungi. Environ Microbiol (2014) 0.83
Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium tuberculosis. Biochim Biophys Acta (2014) 0.82
Novel Polyoxyethylene-Containing Glycolipids Are Synthesized in Corynebacterium matruchotii and Mycobacterium smegmatis Cultured in the Presence of Tween 80. J Lipids (2010) 0.80
Emerging facets of prokaryotic glycosylation. FEMS Microbiol Rev (2016) 0.79
RND transporters protect Corynebacterium glutamicum from antibiotics by assembling the outer membrane. Microbiologyopen (2014) 0.78
Identification of a mycoloyl transferase selectively involved in O-acylation of polypeptides in Corynebacteriales. J Bacteriol (2013) 0.78
IpsA, a novel LacI-type regulator, is required for inositol-derived lipid formation in Corynebacteria and Mycobacteria. BMC Biol (2013) 0.78
Inactivation of the phosphoglucomutase gene pgm in Corynebacterium glutamicum affects cell shape and glycogen metabolism. Biosci Rep (2013) 0.76
BRENDA, the enzyme database: updates and major new developments. Nucleic Acids Res (2004) 8.21
BRENDA, enzyme data and metabolic information. Nucleic Acids Res (2002) 7.92
Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science (2008) 5.30
BRENDA, AMENDA and FRENDA the enzyme information system: new content and tools in 2009. Nucleic Acids Res (2008) 4.75
IntEnz, the integrated relational enzyme database. Nucleic Acids Res (2004) 4.65
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. J Biotechnol (2003) 4.40
QMEAN: A comprehensive scoring function for model quality assessment. Proteins (2008) 3.90
BRENDA, the enzyme information system in 2011. Nucleic Acids Res (2010) 3.83
Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus. PLoS One (2009) 3.53
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer. Genome Res (2007) 3.45
GC-MS libraries for the rapid identification of metabolites in complex biological samples. FEBS Lett (2005) 3.29
Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence. PLoS Pathog (2008) 3.02
BRENDA, AMENDA and FRENDA: the enzyme information system in 2007. Nucleic Acids Res (2007) 2.94
Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state. J Bacteriol (2008) 2.60
The structural basis of secondary active transport mechanisms. Biochim Biophys Acta (2010) 2.56
High concentrations of therapeutic IgG1 antibodies are needed to compensate for inhibition of antibody-dependent cellular cytotoxicity by excess endogenous immunoglobulin G. Mol Immunol (2005) 2.54
A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms. Proc Natl Acad Sci U S A (2003) 2.50
CUPSAT: prediction of protein stability upon point mutations. Nucleic Acids Res (2006) 2.38
BRENDA in 2013: integrated reactions, kinetic data, enzyme function data, improved disease classification: new options and contents in BRENDA. Nucleic Acids Res (2012) 2.33
SNP-based analysis of genetic substructure in the German population. Hum Hered (2006) 2.21
MetaboliteDetector: comprehensive analysis tool for targeted and nontargeted GC/MS based metabolome analysis. Anal Chem (2009) 2.17
BRENDA: a resource for enzyme data and metabolic information. Trends Biochem Sci (2002) 1.97
Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins. PLoS Pathog (2010) 1.76
The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis. J Biol Chem (2005) 1.74
The BRENDA Tissue Ontology (BTO): the first all-integrating ontology of all organisms for enzyme sources. Nucleic Acids Res (2010) 1.71
MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. Mol Immunol (2005) 1.69
The structure of an inverting GH43 beta-xylosidase from Geobacillus stearothermophilus with its substrate reveals the role of the three catalytic residues. J Mol Biol (2006) 1.63
Deletion of the genes encoding the MtrA-MtrB two-component system of Corynebacterium glutamicum has a strong influence on cell morphology, antibiotics susceptibility and expression of genes involved in osmoprotection. Mol Microbiol (2004) 1.57
Metabolic pathway analysis web service (Pathway Hunter Tool at CUBIC). Bioinformatics (2004) 1.56
Chassis organism from Corynebacterium glutamicum--a top-down approach to identify and delete irrelevant gene clusters. Biotechnol J (2014) 1.56
Three pathways for trehalose metabolism in Corynebacterium glutamicum ATCC13032 and their significance in response to osmotic stress. Mol Microbiol (2003) 1.55
SYSTOMONAS--an integrated database for systems biology analysis of Pseudomonas. Nucleic Acids Res (2007) 1.55
Bacterial outer membrane secretin PulD assembles and inserts into the inner membrane in the absence of its pilotin. EMBO J (2006) 1.52
Structure of the dodecameric Yersinia enterocolitica secretin YscC and its trypsin-resistant core. Structure (2013) 1.49
The impact of the absence of glycopeptidolipids on the ultrastructure, cell surface and cell wall properties, and phagocytosis of Mycobacterium smegmatis. Microbiology (2002) 1.49
The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2007) 1.49
In vivo functional characterization of the Escherichia coli ammonium channel AmtB: evidence for metabolic coupling of AmtB to glutamine synthetase. Biochem J (2005) 1.46
Cytotoxin ClyA from Escherichia coli assembles to a 13-meric pore independent of its redox-state. EMBO J (2006) 1.43
Gap, a mycobacterial specific integral membrane protein, is required for glycolipid transport to the cell surface. Mol Microbiol (2005) 1.42
Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex. J Biol Chem (2004) 1.41
Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice. Mol Microbiol (2008) 1.40
Isolation and characterization of low nucleic acid (LNA)-content bacteria. ISME J (2009) 1.38
MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II. Microbiology (2002) 1.36
Crystal structure and snapshots along the reaction pathway of a family 51 alpha-L-arabinofuranosidase. EMBO J (2003) 1.35
The substrate specificity-determining amino acid code of 4-coumarate:CoA ligase. Proc Natl Acad Sci U S A (2003) 1.35
Breaking down the wall: fractionation of mycobacteria. J Microbiol Methods (2006) 1.35
The BCCT family of carriers: from physiology to crystal structure. Mol Microbiol (2010) 1.34
Protein-protein interactions within the Fatty Acid Synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability. Mol Microbiol (2004) 1.34
Multidrug resistance of a porin deletion mutant of Mycobacterium smegmatis. Antimicrob Agents Chemother (2004) 1.34
The cell envelope structure and properties of Mycobacterium smegmatis mc(2)155: is there a clue for the unique transformability of the strain? Microbiology (2005) 1.34
Reconstitution of two recombinant LSm protein complexes reveals aspects of their architecture, assembly, and function. J Biol Chem (2005) 1.31
LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis. EMBO J (2006) 1.31
Biochemical characterization and identification of the catalytic residues of a family 43 beta-D-xylosidase from Geobacillus stearothermophilus T-6. Biochemistry (2005) 1.29
Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis. Mol Microbiol (2002) 1.28
Phage T5 straight tail fiber is a multifunctional protein acting as a tape measure and carrying fusogenic and muralytic activities. J Biol Chem (2008) 1.28
The importance of uniformity in reporting protein-function data. Trends Biochem Sci (2005) 1.27
Technology-specific error signatures in the 1000 Genomes Project data. Hum Genet (2011) 1.27
Observing local and global properties of metabolic pathways: 'load points' and 'choke points' in the metabolic networks. Bioinformatics (2006) 1.26
Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG. J Bacteriol (2007) 1.26
In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment. Int J Cancer (2002) 1.26
Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism. Nat Chem Biol (2013) 1.26
Atomic resolution structures of R-specific alcohol dehydrogenase from Lactobacillus brevis provide the structural bases of its substrate and cosubstrate specificity. J Mol Biol (2005) 1.25
Genomics of glycopeptidolipid biosynthesis in Mycobacterium abscessus and M. chelonae. BMC Genomics (2007) 1.24
Regulation of GlnK activity: modification, membrane sequestration and proteolysis as regulatory principles in the network of nitrogen control in Corynebacterium glutamicum. Mol Microbiol (2004) 1.23
Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival. J Bacteriol (2005) 1.23
Mycobacterium tuberculosis lineage influences innate immune response and virulence and is associated with distinct cell envelope lipid profiles. PLoS One (2011) 1.22
Characterization of the motion of membrane proteins using high-speed atomic force microscopy. Nat Nanotechnol (2012) 1.22
Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycoserosate in the Mycobacterium tuberculosis complex. J Biol Chem (2004) 1.20
The biosynthesis of mycolic acids in Mycobacterium tuberculosis relies on multiple specialized elongation complexes interconnected by specific protein-protein interactions. J Mol Biol (2005) 1.20
BKM-react, an integrated biochemical reaction database. BMC Biochem (2011) 1.19
Identification of the polyketide synthase involved in the biosynthesis of the surface-exposed lipooligosaccharides in mycobacteria. J Bacteriol (2009) 1.19
Projection structure of a member of the amino acid/polyamine/organocation transporter superfamily. J Biol Chem (2008) 1.19
T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells. Proc Natl Acad Sci U S A (2010) 1.18
Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation. J Immunol (2009) 1.17
Closely related Campylobacter jejuni strains from different sources reveal a generalist rather than a specialist lifestyle. BMC Genomics (2011) 1.17
Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding. J Biol Chem (2008) 1.16
The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis. J Biol Chem (2009) 1.14
Development of a classification scheme for disease-related enzyme information. BMC Bioinformatics (2011) 1.14
p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis. J Biol Chem (2005) 1.13
EnzymeDetector: an integrated enzyme function prediction tool and database. BMC Bioinformatics (2011) 1.12
Localization and function of the yeast multidrug transporter Tpo1p. J Biol Chem (2003) 1.12
YaeT-independent multimerization and outer membrane association of secretin PulD. Mol Microbiol (2007) 1.12
The key role of the mycolic acid content in the functionality of the cell wall permeability barrier in Corynebacterineae. Microbiology (2007) 1.12
Further insight into S-adenosylmethionine-dependent methyltransferases: structural characterization of Hma, an enzyme essential for the biosynthesis of oxygenated mycolic acids in Mycobacterium tuberculosis. J Biol Chem (2005) 1.11
Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p. J Mol Biol (2008) 1.09
Identification and characterization of the dicarboxylate uptake system DccT in Corynebacterium glutamicum. J Bacteriol (2008) 1.09
Regulatory properties and interaction of the C- and N-terminal domains of BetP, an osmoregulated betaine transporter from Corynebacterium glutamicum. Biochemistry (2008) 1.08
The crystal structure of R-specific alcohol dehydrogenase from Lactobacillus brevis suggests the structural basis of its metal dependency. J Mol Biol (2003) 1.08
Regulation of AmtR-controlled gene expression in Corynebacterium glutamicum: mechanism and characterization of the AmtR regulon. Mol Microbiol (2005) 1.08