Published in Biochem Biophys Res Commun on July 08, 2005
Selection of a T7 promoter mutant with enhanced in vitro activity by a novel multi-copy bead display approach for in vitro evolution. Nucleic Acids Res (2012) 0.90
Potential of phage-displayed peptide library technology to identify functional targeting peptides. Expert Opin Drug Discov (2007) 0.87
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim Biophys Acta (2011) 2.50
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J Biol Chem (2003) 2.30
Emerging roles of cysteine cathepsins in disease and their potential as drug targets. Curr Pharm Des (2007) 2.26
Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement. Lancet Infect Dis (2008) 1.96
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues. J Biol Chem (2008) 1.85
Lysosomes and lysosomal cathepsins in cell death. Biochim Biophys Acta (2011) 1.61
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment. Nat Nanotechnol (2011) 1.41
Improved determination of plasmid copy number using quantitative real-time PCR for monitoring fermentation processes. Microb Cell Fact (2008) 1.32
Autophagy is involved in nutritional stress response and differentiation in Trypanosoma cruzi. J Biol Chem (2007) 1.31
Phage display: selecting straws instead of a needle from a haystack. Molecules (2011) 1.30
Lysosomal cysteine cathepsins: signaling pathways in apoptosis. Biol Chem (2007) 1.29
Autophagy in protists. Autophagy (2011) 1.29
Peptide phage display as a tool for drug discovery: targeting membrane receptors. Molecules (2011) 1.28
Cysteine cathepsins (proteases)--on the main stage of cancer? Cancer Cell (2004) 1.27
Production and activation of recombinant papain-like cysteine proteases. Methods (2004) 1.18
Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence. Am J Pathol (2012) 1.16
Lysosomal pathways to cell death and their therapeutic applications. Exp Cell Res (2012) 1.15
Lysosomes in apoptosis. Methods Enzymol (2008) 1.13
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis. Biol Chem (2010) 1.13
Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells. J Ind Microbiol Biotechnol (2013) 1.13
Lysosomal-mitochondrial cross-talk during cell death. Mitochondrion (2010) 1.11
Metacaspases of Trypanosoma cruzi: possible candidates for programmed cell death mediators. Mol Biochem Parasitol (2005) 1.10
Protective effects of fullerenol C60(OH)24 against doxorubicin-induced cardiotoxicity and hepatotoxicity in rats with colorectal cancer. Biomaterials (2008) 1.09
Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer. Adv Enzyme Regul (2002) 1.08
Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells. Exp Cell Res (2006) 1.05
Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion. Biochimie (2007) 1.05
Stefin B interacts with histones and cathepsin L in the nucleus. J Biol Chem (2010) 1.04
Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions. J Biol Chem (2007) 1.04
Acute doxorubicin nephrotoxicity in rats with malignant neoplasm can be successfully treated with fullerenol C60(OH)24 via suppression of oxidative stress. Pharmacol Rep (2008) 1.03
Autocatalytic processing of procathepsin B is triggered by proenzyme activity. FEBS J (2009) 1.02
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues. Exp Cell Res (2005) 1.02
Lysosomal cysteine proteases: structural features and their role in apoptosis. IUBMB Life (2005) 1.01
Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett (2005) 1.00
Molecular basis of Colorado potato beetle adaptation to potato plant defence at the level of digestive cysteine proteinases. Insect Biochem Mol Biol (2004) 0.99
Cathepsin X binds to cell surface heparan sulfate proteoglycans. Arch Biochem Biophys (2005) 0.99
Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins. Immunology (2008) 0.98
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation. Bioorg Med Chem (2010) 0.97
Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase. J Mol Biol (2007) 0.95
Selective activity-based probes for cysteine cathepsins. Angew Chem Int Ed Engl (2008) 0.94
Potential hepatoprotective effects of fullerenol C60(OH)24 in doxorubicin-induced hepatotoxicity in rats with mammary carcinomas. Biomaterials (2008) 0.93
Inhibitory properties of cystatin F and its localization in U937 promonocyte cells. FEBS J (2005) 0.93
DNA accelerates the inhibition of human cathepsin V by serpins. J Biol Chem (2007) 0.92
Comprehensive search for cysteine cathepsins in the human genome. Biol Chem (2004) 0.92
Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme. J Med Chem (2008) 0.92
Basidiomycetes harbour a hidden treasure of proteolytic diversity. J Biotechnol (2006) 0.92
Cysteine cathepsins and their potential in clinical therapy and biomarker discovery. Proteomics Clin Appl (2014) 0.90
Cysteine proteases: destruction ability versus immunomodulation capacity in immune cells. Biol Chem (2007) 0.90
Expression of sea anemone equistatin in potato. Effects of plant proteases on heterologous protein production. Plant Physiol (2003) 0.89
Folding, stability, and secondary structure of a new dimeric cysteine proteinase inhibitor. Biochem Biophys Res Commun (2002) 0.89
Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry (2003) 0.89
Purification, characterization and cloning of a ricin B-like lectin from mushroom Clitocybe nebularis with antiproliferative activity against human leukemic T cells. Biochim Biophys Acta (2008) 0.89
Nuclear cysteine cathepsin variants in thyroid carcinoma cells. Biol Chem (2010) 0.88
In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {beta}-lactamase inhibitor. Antimicrob Agents Chemother (2008) 0.88
Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L. Biol Chem (2005) 0.87
Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation. BMC Microbiol (2010) 0.87
Acute cardioprotective and cardiotoxic effects of bilberry anthocyanins in ischemia-reperfusion injury: beyond concentration-dependent antioxidant activity. Cardiovasc Toxicol (2010) 0.87
Improvement of arterial wall characteristics by the low-dose fluvastatin and valsartan combination in type 1 diabetes mellitus patients. Diab Vasc Dis Res (2013) 0.87
Endophytic fungi: the treasure chest of antibacterial substances. Phytomedicine (2012) 0.87
Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target. Front Pharmacol (2012) 0.86
The role of gender and sex hormones in ischemic-reperfusion injury in isolated rat hearts. Eur J Pharmacol (2007) 0.86
A role for serglycin proteoglycan in mast cell apoptosis induced by a secretory granule-mediated pathway. J Biol Chem (2010) 0.86
Cleavage of MAGI-1, a tight junction PDZ protein, by caspases is an important step for cell-cell detachment in apoptosis. Apoptosis (2007) 0.86
Determination of cichoric acid content in dried press juice of purple coneflower (Echinacea purpurea) with capillary electrophoresis. Talanta (2005) 0.86
Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L. Immunology (2010) 0.85
Cellular localization of MAGI-1 caspase cleavage products and their role in apoptosis. Biol Chem (2007) 0.85
4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity. J Med Chem (2007) 0.85
Acute doxorubicin pulmotoxicity in rats with malignant neoplasm is effectively treated with fullerenol C60(OH)24 through inhibition of oxidative stress. Pharmacol Rep (2009) 0.85
Engineered lactic acid bacterium Lactococcus lactis capable of binding antibodies and tumor necrosis factor alpha. Appl Environ Microbiol (2010) 0.85
The endolysosomal system in cell death and survival. Cold Spring Harb Perspect Biol (2013) 0.85
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus. Biochem Pharmacol (2008) 0.85
Blocking autophagy to prevent parasite differentiation: a possible new strategy for fighting parasitic infections? Autophagy (2008) 0.85
Screening of selected food and medicinal plant extracts for pancreatic lipase inhibition. Phytother Res (2009) 0.85
A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites. Int J Biochem Cell Biol (2009) 0.84
Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins. FEBS Lett (2005) 0.84
Effects of high-fat mixed-lipid diet and exercise on the antioxidant system in skeletal and cardiac muscles of rats with colon carcinoma. Pharmacol Rep (2009) 0.84
Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation. Front Mol Neurosci (2012) 0.84
Identification of herbarium whole-leaf samples of Epilobium species by ATR-IR spectroscopy. Chem Biodivers (2008) 0.84
Expression of the sweet-tasting plant protein brazzein in Escherichia coli and Lactococcus lactis: a path toward sweet lactic acid bacteria. Appl Microbiol Biotechnol (2006) 0.83
Cleavage of the myristoylated alanine-rich C kinase substrate (MARCKS) by cysteine cathepsins in cells and tissues of stefin B-deficient mice. Biol Chem (2007) 0.83
Comparison of bacterial and phage display peptide libraries in search of target-binding motif. Appl Biochem Biotechnol (2005) 0.82
Comparison of 3 cytotoxicity screening assays and their application to the selection of novel antibacterial hits. J Biomol Screen (2009) 0.82
In vivo imaging of mouse tumors by a lipidated cathepsin S substrate. Angew Chem Int Ed Engl (2014) 0.82
Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets? Biochem Soc Symp (2003) 0.81
Fullerenol nanoparticles: toxicity and antioxidant activity. Methods Mol Biol (2013) 0.81
Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe. Chem Biol (2010) 0.81
hDLG/SAP97, a member of the MAGUK protein family, is a novel caspase target during cell-cell detachment in apoptosis. Biol Chem (2005) 0.81
Engineered staphylococcal protein A's IgG-binding domain with cathepsin L inhibitory activity. Biochem Biophys Res Commun (2006) 0.81
Diverse enzymatic specificities of digestive proteases, 'intestains', enable Colorado potato beetle larvae to counteract the potato defence mechanism. Biol Chem (2003) 0.81
Basidiomycete Clitocybe nebularis is rich in lectins with insecticidal activities. Appl Microbiol Biotechnol (2011) 0.81
Heterogeneity in the cysteine protease inhibitor clitocypin gene family. Biol Chem (2006) 0.81
Rutin in buckwheat herbs grown at different UV-B radiation levels: comparison of two UV spectrophotometric and an HPLC method. J Exp Bot (2002) 0.81
Unnatural amino acids increase activity and specificity of synthetic substrates for human and malarial cathepsin C. Amino Acids (2014) 0.81