Published in Cell on March 27, 2014
RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells. Science (2015) 3.49
Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science (2014) 2.78
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function. Neuron (2015) 2.63
Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions. Cell (2014) 1.89
APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly. Cell (2014) 1.74
Translation dynamics of single mRNAs in live cells and neurons. Science (2016) 1.45
The neurology of mTOR. Neuron (2014) 1.43
Translational activation of oskar mRNA: reevaluation of the role and importance of a 5' regulatory element [corrected]. PLoS One (2015) 1.42
Real-Time Imaging of Translation on Single mRNA Transcripts in Live Cells. Cell (2016) 1.41
Post-transcriptional RNA regulons affecting cell cycle and proliferation. Semin Cell Dev Biol (2014) 0.99
Ribosome profiling reveals the what, when, where and how of protein synthesis. Nat Rev Mol Cell Biol (2015) 0.99
mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging. Ann N Y Acad Sci (2015) 0.93
Region-specific activation of oskar mRNA translation by inhibition of Bruno-mediated repression. PLoS Genet (2015) 0.91
Tunable protein synthesis by transcript isoforms in human cells. Elife (2016) 0.88
Rac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis. Front Cell Neurosci (2014) 0.88
RiboTag is a flexible tool for measuring the translational state of targeted cells in heterogeneous cell cultures. Biotechniques (2015) 0.88
Unmasking the messenger. RNA Biol (2014) 0.87
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nat Commun (2015) 0.86
Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth. J Neurosci (2015) 0.84
Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems. Nat Struct Mol Biol (2014) 0.84
Diffusion dynamics of synaptic molecules during inhibitory postsynaptic plasticity. Front Cell Neurosci (2014) 0.84
Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation. Genome Biol (2015) 0.83
The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability. Nat Neurosci (2016) 0.82
Targeting axonal protein synthesis in neuroregeneration and degeneration. Neurotherapeutics (2015) 0.82
Visualization of single endogenous polysomes reveals the dynamics of translation in live human cells. J Cell Biol (2016) 0.81
Synaptic adaptations by alcohol and drugs of abuse: changes in microRNA expression and mRNA regulation. Front Mol Neurosci (2014) 0.81
Plasticity-related microRNA and their potential contribution to the maintenance of long-term potentiation. Front Mol Neurosci (2015) 0.81
Growth Cone Localization of the mRNA Encoding the Chromatin Regulator HMGN5 Modulates Neurite Outgrowth. Mol Cell Biol (2015) 0.80
The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease. Biochem Soc Trans (2016) 0.79
Meet the players: local translation at the synapse. Front Mol Neurosci (2014) 0.79
Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size. Cell Rep (2016) 0.79
Control of cell migration through mRNA localization and local translation. Wiley Interdiscip Rev RNA (2014) 0.79
Signaling Over Distances. Mol Cell Proteomics (2015) 0.78
Role of Splice Variants of Gtf2i, a Transcription Factor Localizing at Postsynaptic Sites, and Its Relation to Neuropsychiatric Diseases. Int J Mol Sci (2017) 0.78
The epitranscriptome in modulating spatiotemporal RNA translation in neuronal post-synaptic function. Front Cell Neurosci (2015) 0.77
Non-coding functions of alternative pre-mRNA splicing in development. Semin Cell Dev Biol (2015) 0.77
Long-term reduction of T-cell intracellular antigens leads to increased beta-actin expression. Mol Cancer (2014) 0.77
Drosophila Shep and C. elegans SUP-26 are RNA-binding proteins that play diverse roles in nervous system development. Dev Genes Evol (2015) 0.77
Highly specific imaging of mRNA in single cells by target RNA-initiated rolling circle amplification. Chem Sci (2017) 0.76
Evolution of the unspliced transcriptome. BMC Evol Biol (2015) 0.76
Regulation of global and specific mRNA translation by the mTOR signaling pathway. Translation (Austin) (2015) 0.76
Temporal patterns of gene expression during calyx of held development. Dev Neurobiol (2015) 0.76
mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors. Mol Psychiatry (2016) 0.76
Muscle injury, impaired muscle function and insulin resistance in Chromogranin A-knockout mice. J Endocrinol (2016) 0.76
Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development. Sci Rep (2016) 0.75
Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release. Neuron (2016) 0.75
Assessment of TTX-s and TTX-r Action Potential Conduction along Neurites of NGF and GDNF Cultured Porcine DRG Somata. PLoS One (2015) 0.75
RNP transport in cell biology: the long and winding road. Curr Opin Cell Biol (2017) 0.75
T-type Ca2+ channels are required for enhanced sympathetic axon growth by TNFα reverse signalling. Open Biol (2017) 0.75
Monitoring mRNA Translation in Neuronal Processes Using Fluorescent Non-Canonical Amino Acid Tagging. J Histochem Cytochem (2016) 0.75
Dysregulation of mRNA Localization and Translation in Genetic Disease. J Neurosci (2016) 0.75
Imaging Single-mRNA Localization and Translation in Live Neurons. Mol Cells (2016) 0.75
Community effects in regulation of translation. Elife (2016) 0.75
RNA-binding proteins in eye development and disease: implication of conserved RNA granule components. Wiley Interdiscip Rev RNA (2016) 0.75
mTOR and MAPK: from localized translation control to epilepsy. BMC Neurosci (2016) 0.75
Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain. Curr Biol (2016) 0.75
A beacon in the cytoplasm: Tracking translation of single mRNAs. J Cell Biol (2016) 0.75
GC3-biased gene domains in mammalian genomes. Bioinformatics (2015) 0.75
Tma108, a putative M1 aminopeptidase, is a specific nascent chain-associated protein in Saccharomyces cerevisiae. Nucleic Acids Res (2016) 0.75
Disruption of the Axonal Trafficking of Tyrosine Hydroxylase mRNA Impairs Catecholamine Biosynthesis in the Axons of Sympathetic Neurons. eNeuro (2017) 0.75
eIF4A RNA Helicase Associates with Cyclin-Dependent Protein Kinase A in Proliferating Cells and Is Modulated by Phosphorylation. Plant Physiol (2016) 0.75
Genome-wide analysis of mRNAs associated with mouse peroxisomes. BMC Genomics (2016) 0.75
Mechanism of β-actin mRNA Recognition by ZBP1. Cell Rep (2017) 0.75
Neuronal function of the mRNA decapping complex determines survival of Caenorhabditis elegans at high temperature through temporal regulation of heterochronic gene expression. Open Biol (2017) 0.75
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs. Nat Commun (2016) 0.75
Stable Membrane-Association of mRNAs in Etiolated, Greening and Mature Plastids. Int J Mol Sci (2017) 0.75
Significance of MNK1 in prognostic prediction and chemotherapy development of epithelial ovarian cancer. Clin Transl Oncol (2017) 0.75
Maintenance of Miranda Localization in Drosophila Neuroblasts Involves Interaction with the Cognate mRNA. Curr Biol (2017) 0.75
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
mTOR signaling in growth control and disease. Cell (2012) 29.21
Global quantification of mammalian gene expression control. Nature (2011) 22.36
Upstream and downstream of mTOR. Genes Dev (2004) 21.61
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science (2009) 20.75
Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell (2000) 17.44
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem (1999) 14.59
Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell (2009) 14.51
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science (2008) 14.09
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science (2009) 13.45
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science (2009) 12.99
Specific interference by ingested dsRNA. Nature (1998) 11.82
A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature (1994) 11.50
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science (1991) 10.16
[Operon: a group of genes with the expression coordinated by an operator]. C R Hebd Seances Acad Sci (1960) 9.68
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function. Nature (1994) 9.30
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46
Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell (2007) 8.43
Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev (2001) 7.60
Evidence for translational regulation of the activator of general amino acid control in yeast. Proc Natl Acad Sci U S A (1984) 7.23
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science (1997) 7.07
Autism spectrum disorders: developmental disconnection syndromes. Curr Opin Neurobiol (2007) 6.96
Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell (2012) 6.83
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell (2001) 6.50
Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol (2004) 6.38
Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system. Nat Neurosci (2003) 5.83
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell (2000) 5.49
Dendritic protein synthesis, synaptic plasticity, and memory. Cell (2006) 5.18
mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci (2009) 5.04
Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays. Proc Natl Acad Sci U S A (2000) 4.99
Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron (2001) 4.70
Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs. Mol Cell Biol (1993) 4.63
Intracellular localization of messenger RNAs for cytoskeletal proteins. Cell (1986) 4.53
Eukaryotic mRNPs may represent posttranscriptional operons. Mol Cell (2002) 4.39
Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies. Cell (2012) 4.37
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses. Cell (2003) 4.34
New initiation factor activity required for globin mRNA translation. J Biol Chem (1983) 4.31
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Cell (2011) 4.26
Tuberous sclerosis. Lancet (2008) 4.24
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus. Proc Natl Acad Sci U S A (2001) 4.16
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature (2013) 4.03
Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets. Cell (2005) 4.02
Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron (1998) 3.95
Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron (2001) 3.84
The autistic neuron: troubled translation? Cell (2008) 3.81
Highly multiplexed subcellular RNA sequencing in situ. Science (2014) 3.77
Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1. Nat Neurosci (2006) 3.74
Involvement of eukaryotic initiation factor 4A in the cap recognition process. J Biol Chem (1983) 3.70
Non-ATG-initiated translation directed by microsatellite expansions. Proc Natl Acad Sci U S A (2010) 3.58
Sustained translational repression by eIF2α-P mediates prion neurodegeneration. Nature (2012) 3.54
eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell (2007) 3.46
Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. J Neurosci (1998) 3.45
Rates of in situ transcription and splicing in large human genes. Nat Struct Mol Biol (2009) 3.39
An essential role for beta-actin mRNA localization and translation in Ca2+-dependent growth cone guidance. Nat Neurosci (2006) 3.30
Dendritic mRNA: transport, translation and function. Nat Rev Neurosci (2007) 3.29
Local translation of RhoA regulates growth cone collapse. Nature (2005) 3.26
Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature (2012) 3.13
Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell (2002) 3.11
Arginylation of beta-actin regulates actin cytoskeleton and cell motility. Science (2006) 3.05
FMRP targets distinct mRNA sequence elements to regulate protein expression. Nature (2012) 2.95
CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome. Neuron (2013) 2.94
cis-acting sequences responsible for anterior localization of bicoid mRNA in Drosophila embryos. Nature (1988) 2.89
Eukaryotic mRNA cap binding protein: purification by affinity chromatography on sepharose-coupled m7GDP. Proc Natl Acad Sci U S A (1979) 2.81
Synapse- and stimulus-specific local translation during long-term neuronal plasticity. Science (2009) 2.74
Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon. Neuron (2002) 2.69
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2. Nature (2005) 2.67
The ribosome filter hypothesis. Proc Natl Acad Sci U S A (2002) 2.64
Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility. Neuron (2001) 2.57
Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol (2007) 2.54
Subcellular mRNA localization in animal cells and why it matters. Science (2009) 2.54
The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging. Neuron (2012) 2.53
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
Axonal mRNA in uninjured and regenerating cortical mammalian axons. J Neurosci (2009) 2.48
Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones. Neuron (2006) 2.45
Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivo. Curr Biol (1999) 2.45
Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration. J Neurosci (2005) 2.42
Altered ribostasis: RNA-protein granules in degenerative disorders. Cell (2013) 2.38
How and why does beta-actin mRNA target? Biol Cell (2005) 2.38
Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival. Nat Cell Biol (2008) 2.37
A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nat Neurosci (2004) 2.36
Splicing segregation: the minor spliceosome acts outside the nucleus and controls cell proliferation. Cell (2007) 2.33
Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites. J Neurosci (2004) 2.29
Cytoplasmic polyadenylation in development and beyond. Microbiol Mol Biol Rev (1999) 2.29
Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair. Nat Rev Neurosci (2012) 2.27
Reversible glutathionylation regulates actin polymerization in A431 cells. J Biol Chem (2001) 2.26
Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Cell (2010) 2.23
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (2014) 2.23
mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons. FEBS Lett (2007) 2.22
Molecular profiling of activated neurons by phosphorylated ribosome capture. Cell (2012) 2.22
The mechanism of eukaryotic translation initiation: new insights and challenges. Cold Spring Harb Perspect Biol (2012) 2.21
The central dogma decentralized: new perspectives on RNA function and local translation in neurons. Neuron (2013) 2.21
Visualization of dynamics of single endogenous mRNA labeled in live mouse. Science (2014) 2.20
RNA localization in yeast: moving towards a mechanism. Biol Cell (2005) 2.15
RNA-RNA interaction is required for the formation of specific bicoid mRNA 3' UTR-STAUFEN ribonucleoprotein particles. EMBO J (1997) 2.13
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. RNA (2010) 2.07
Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs. J Neurosci (2010) 2.02
Facilitation of dendritic mRNA transport by CPEB. Genes Dev (2003) 2.00
Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. Nature (2008) 1.98
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. J Cell Sci (2005) 1.95
Localized CCR2 Activation in the Bone Marrow Niche Mobilizes Monocytes by Desensitizing CXCR4. PLoS One (2015) 0.80
Diverse cap-binding properties of Drosophila eIF4E isoforms. Biochim Biophys Acta (2016) 0.75