Published in Am J Physiol Cell Physiol on June 01, 2005
JAM-A regulates permeability and inflammation in the intestine in vivo. J Exp Med (2007) 2.63
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MicroRNA-204/211 alters epithelial physiology. FASEB J (2010) 1.83
Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. Am J Pathol (2007) 1.39
Regulation and roles for claudin-family tight junction proteins. IUBMB Life (2009) 1.26
Claudin-8 expression in renal epithelial cells augments the paracellular barrier by replacing endogenous claudin-2. J Membr Biol (2007) 1.05
Helicobacter pylori targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells. Gut (2014) 1.03
Roles for claudins in alveolar epithelial barrier function. Ann N Y Acad Sci (2012) 0.92
Signal transducer and activator of transcription 3 (STAT3) protein suppresses adenoma-to-carcinoma transition in Apcmin/+ mice via regulation of Snail-1 (SNAI) protein stability. J Biol Chem (2012) 0.92
Glutamatergic signaling maintains the epithelial phenotype of proximal tubular cells. J Am Soc Nephrol (2011) 0.89
Bacterial induction of Snail1 contributes to blood-brain barrier disruption. J Clin Invest (2015) 0.87
The integrin β1 subunit regulates paracellular permeability of kidney proximal tubule cells. J Biol Chem (2014) 0.86
Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeability. Alcohol Clin Exp Res (2011) 0.85
Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis. FASEB J (2014) 0.83
The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4. PLoS One (2013) 0.79
Segmental Differences in Radiation-Induced Alterations of Tight Junction-Related Proteins in Non-Human Primate Jejunum, Ileum and Colon. Radiat Res (2015) 0.77
Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis. Biomed Res Int (2015) 0.76
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier. Oncotarget (2016) 0.76
The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184. J Cell Sci (2016) 0.75
Par3 regulates invasion of pancreatic cancer cells via interaction with Tiam1. Clin Exp Med (2015) 0.75
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer (2007) 18.69
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet (2005) 8.45
Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res (2008) 6.95
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci (2003) 6.24
Bi-directional protein transport between the ER and Golgi. Annu Rev Cell Dev Biol (2004) 6.10
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene (2005) 5.74
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell (2012) 5.53
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature (2008) 4.60
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem (2003) 4.55
Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell (2003) 4.23
Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene (2002) 4.20
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol (2004) 4.15
Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle. Cell (2005) 3.96
Transcriptional regulation of cadherins during development and carcinogenesis. Int J Dev Biol (2004) 3.64
Lipid homeostasis, lipotoxicity and the metabolic syndrome. Biochim Biophys Acta (2009) 2.84
SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells. Cancer Res (2007) 2.80
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res (2006) 2.73
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression. EMBO J (2005) 2.71
Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking. Nat Genet (2006) 2.39
The genetic basis of a craniofacial disease provides insight into COPII coat assembly. Dev Cell (2007) 2.26
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition. J Biol Chem (2008) 2.22
Lipoapoptosis: its mechanism and its diseases. Biochim Biophys Acta (2002) 2.10
The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells. Biochem J (2006) 2.03
Rapid transformation of white adipocytes into fat-oxidizing machines. Proc Natl Acad Sci U S A (2004) 2.03
Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America. Circ Res (2007) 1.97
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome. Proc Natl Acad Sci U S A (2008) 1.89
Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor. J Cell Sci (2005) 1.87
Paracrinology of islets and the paracrinopathy of diabetes. Proc Natl Acad Sci U S A (2010) 1.79
Diabetes and apoptosis: lipotoxicity. Apoptosis (2009) 1.75
Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3. Proc Natl Acad Sci U S A (2002) 1.73
Coordination of COPII vesicle trafficking by Sec23. Trends Cell Biol (2008) 1.70
Aldosterone activates NF-kappaB in the collecting duct. J Am Soc Nephrol (2008) 1.67
The epithelial-mesenchymal transition under control: global programs to regulate epithelial plasticity. Semin Cancer Biol (2012) 1.65
Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma. J Pathol (2010) 1.63
Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis. Mol Biol Cell (2003) 1.62
The morphological and molecular features of the epithelial-to-mesenchymal transition. Nat Protoc (2009) 1.60
The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis. Mol Biol Cell (2006) 1.58
Sec16p potentiates the action of COPII proteins to bud transport vesicles. J Cell Biol (2002) 1.55
Uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex II vesicles. J Biol Chem (2004) 1.52
Exomer: A coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast. J Cell Biol (2006) 1.52
Fat storage in adipocytes requires inactivation of leptin's paracrine activity: implications for treatment of human obesity. Proc Natl Acad Sci U S A (2005) 1.52
Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo. J Cell Sci (2004) 1.50
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas. Cancer Res (2008) 1.48
A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors. Cancer Res (2004) 1.44
GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes. EMBO J (2004) 1.43
Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions. Oncogene (2004) 1.39
Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack. Mol Biol Cell (2004) 1.39
Osmoprotective transcription factor NFAT5/TonEBP modulates nuclear factor-kappaB activity. Mol Biol Cell (2010) 1.38
Generation and characterization of telomerase-transfected human lymphatic endothelial cells with an extended life span. Am J Pathol (2004) 1.35
The class I bHLH factors E2-2A and E2-2B regulate EMT. J Cell Sci (2009) 1.34
SPARC represses E-cadherin and induces mesenchymal transition during melanoma development. Cancer Res (2006) 1.31
Tonicity-responsive enhancer binding protein is an essential regulator of aquaporin-2 expression in renal collecting duct principal cells. J Am Soc Nephrol (2006) 1.28
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas. EMBO Mol Med (2011) 1.28
Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin. Diabetes (2007) 1.26
Phosphorylation of serine 11 and serine 92 as new positive regulators of human Snail1 function: potential involvement of casein kinase-2 and the cAMP-activated kinase protein kinase A. Mol Biol Cell (2009) 1.21
Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria: an ultrastructural study. PLoS One (2012) 1.20
Tumorigenesis: Twist1 links EMT to self-renewal. Nat Cell Biol (2010) 1.17
Calcium-sensing receptor attenuates AVP-induced aquaporin-2 expression via a calmodulin-dependent mechanism. J Am Soc Nephrol (2007) 1.17
i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion. J Cell Biol (2003) 1.14
A resident Golgi protein is excluded from peri-Golgi vesicles in NRK cells. Proc Natl Acad Sci U S A (2002) 1.14
Switching on-off Snail: LOXL2 versus GSK3beta. Cell Cycle (2005) 1.14
PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro. Dev Biol (2003) 1.13
A hypoxic twist in metastasis. Nat Cell Biol (2008) 1.10
Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression. Am J Physiol Cell Physiol (2009) 1.10
Dual effects of hypertonicity on aquaporin-2 expression in cultured renal collecting duct principal cells. J Am Soc Nephrol (2005) 1.08
Self-assembly of minimal COPII cages. EMBO Rep (2003) 1.08
Intracellular Na+ controls cell surface expression of Na,K-ATPase via a cAMP-independent PKA pathway in mammalian kidney collecting duct cells. Mol Biol Cell (2003) 1.07
Differential role of Snail1 and Snail2 zinc fingers in E-cadherin repression and epithelial to mesenchymal transition. J Biol Chem (2013) 1.06
Aquaporin-2 abundance in the renal collecting duct: new insights from cultured cell models. Am J Physiol Renal Physiol (2009) 1.06
Oncostatin M-induced effects on EMT in human proximal tubular cells: differential role of ERK signaling. Am J Physiol Renal Physiol (2007) 1.05
Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells. Am J Physiol Cell Physiol (2003) 1.04
Induction of cortical endoplasmic reticulum by dimerization of a coatomer-binding peptide anchored to endoplasmic reticulum membranes. Proc Natl Acad Sci U S A (2010) 1.04
Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context. Nucleic Acids Res (2011) 1.04
Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN. J Hepatol (2009) 1.04
Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis. J Am Soc Nephrol (2005) 1.04
Tumour necrosis factor alpha confers an invasive, transformed phenotype on mammary epithelial cells. J Cell Sci (2005) 1.03
VE-cadherin expression and clustering maintain low levels of survivin in endothelial cells. Am J Pathol (2004) 1.03
Functional characterization of E- and P-cadherin in invasive breast cancer cells. BMC Cancer (2009) 1.02
NF-kappaB modulates aquaporin-2 transcription in renal collecting duct principal cells. J Biol Chem (2008) 1.01
MODULAR ANALYTICS: A New Approach to Automation in the Clinical Laboratory. J Autom Methods Manag Chem (2005) 1.00
Raf kinase inhibitor protein positively regulates cell-substratum adhesion while negatively regulating cell-cell adhesion. J Cell Biochem (2008) 1.00
ERK1/2 mediates insulin stimulation of Na(+),K(+)-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells. J Biol Chem (2004) 1.00
Posttranscriptional control of aquaporin-2 abundance by vasopressin in renal collecting duct principal cells. Am J Physiol Renal Physiol (2005) 0.99
Insulin potentiates AVP-induced AQP2 expression in cultured renal collecting duct principal cells. Am J Physiol Renal Physiol (2004) 0.97
Id-1 is induced in MDCK epithelial cells by activated Erk/MAPK pathway in response to expression of the Snail and E47 transcription factors. Exp Cell Res (2007) 0.95
A core microRNA signature associated with inducers of the epithelial-to-mesenchymal transition. J Pathol (2014) 0.95
NF-kappaB inhibits sodium transport via down-regulation of SGK1 in renal collecting duct principal cells. J Biol Chem (2008) 0.94
Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Autophagy (2013) 0.94
Rac1 modulates TGF-beta1-mediated epithelial cell plasticity and MMP9 production in transformed keratinocytes. FEBS Lett (2010) 0.94
Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells. Oncogene (2005) 0.94
Transmembrane domains control exclusion of membrane proteins from clathrin-coated pits. J Cell Sci (2010) 0.93
Combined leptin actions on adipose tissue and hypothalamus are required to deplete adipocyte fat in lean rats: implications for obesity treatment. J Biol Chem (2006) 0.92
The [corrected] SEC23-SEC31 [corrected] interface plays critical role for export of procollagen from the endoplasmic reticulum. J Biol Chem (2012) 0.91
cAMP-dependent chloride secretion mediates tubule enlargement and cyst formation by cultured mammalian collecting duct cells. Am J Physiol Renal Physiol (2008) 0.90
Dual influence of aldosterone on AQP2 expression in cultured renal collecting duct principal cells. J Biol Chem (2003) 0.89
Ataxia telangiectasia mutated (ATM) inhibition transforms human mammary gland epithelial cells. J Biol Chem (2010) 0.89
Dynamic transport of SNARE proteins in the Golgi apparatus. Proc Natl Acad Sci U S A (2005) 0.89
A multimarker panel for circulating tumor cells detection predicts patient outcome and therapy response in metastatic colorectal cancer. Int J Cancer (2014) 0.89