Published in Nat Genet on September 17, 2006
Structural basis for cargo regulation of COPII coat assembly. Cell (2008) 3.15
Organization of the ER-Golgi interface for membrane traffic control. Nat Rev Mol Cell Biol (2013) 2.89
Ubiquitin-dependent regulation of COPII coat size and function. Nature (2012) 2.88
Systematic discovery of nonobvious human disease models through orthologous phenotypes. Proc Natl Acad Sci U S A (2010) 2.61
Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31. Dev Cell (2007) 2.42
COPII and the regulation of protein sorting in mammals. Nat Cell Biol (2011) 2.33
The genetic basis of a craniofacial disease provides insight into COPII coat assembly. Dev Cell (2007) 2.26
TFG-1 function in protein secretion and oncogenesis. Nat Cell Biol (2011) 2.13
Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II. Nat Genet (2009) 2.12
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol (2009) 1.90
Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210. N Engl J Med (2010) 1.81
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol (2009) 1.69
Endocytosis and signaling: cell logistics shape the eukaryotic cell plan. Physiol Rev (2012) 1.61
Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol (2011) 1.58
Drosophila Sec16 mediates the biogenesis of tER sites upstream of Sar1 through an arginine-rich motif. Mol Biol Cell (2008) 1.49
The potential of high-content high-throughput microscopy in drug discovery. Br J Pharmacol (2007) 1.42
Assembly, organization, and function of the COPII coat. Histochem Cell Biol (2007) 1.41
cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites. Mol Biol Cell (2011) 1.39
Sec24D-dependent transport of extracellular matrix proteins is required for zebrafish skeletal morphogenesis. PLoS One (2010) 1.35
Vesicle-mediated export from the ER: COPII coat function and regulation. Biochim Biophys Acta (2013) 1.21
SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife (2013) 1.18
COPII - a flexible vesicle formation system. Curr Opin Cell Biol (2013) 1.14
Mutations in SEC24D, encoding a component of the COPII machinery, cause a syndromic form of osteogenesis imperfecta. Am J Hum Genet (2015) 1.13
Vesicle-mediated ER export of proteins and lipids. Biochim Biophys Acta (2012) 1.06
Recent developments in the understanding of the combined deficiency of FV and FVIII. Br J Haematol (2009) 1.05
SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum. Elife (2014) 1.04
SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A (2012) 1.03
The COPII pathway and hematologic disease. Blood (2012) 1.03
The structure of the COPII transport-vesicle coat assembled on membranes. Elife (2013) 1.01
Clinical aspects and pathogenesis of congenital dyserythropoietic anemias: from morphology to molecular approach. Haematologica (2012) 0.99
Golgi glycosylation and human inherited diseases. Cold Spring Harb Perspect Biol (2011) 0.99
Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin. Blood (2011) 0.98
The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis. Dis Model Mech (2011) 0.97
Molecular analysis and intestinal expression of SAR1 genes and proteins in Anderson's disease (Chylomicron retention disease). Orphanet J Rare Dis (2011) 0.96
Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C. J Biol Chem (2013) 0.95
Selective targeting of ER exit sites supports axon development. Traffic (2009) 0.94
Cranio-lenticulo-sutural dysplasia associated with defects in collagen secretion. Clin Genet (2010) 0.94
In vivo cell biology in zebrafish - providing insights into vertebrate development and disease. J Cell Sci (2014) 0.93
Interpreting human genetic variation with in vivo zebrafish assays. Biochim Biophys Acta (2014) 0.92
CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. PLoS One (2013) 0.91
The [corrected] SEC23-SEC31 [corrected] interface plays critical role for export of procollagen from the endoplasmic reticulum. J Biol Chem (2012) 0.91
Disruption of the Sec24d gene results in early embryonic lethality in the mouse. PLoS One (2013) 0.91
Trafficking through COPII stabilises cell polarity and drives secretion during Drosophila epidermal differentiation. PLoS One (2010) 0.90
Mechanisms for exporting large-sized cargoes from the endoplasmic reticulum. Cell Mol Life Sci (2015) 0.89
TFG Promotes Organization of Transitional ER and Efficient Collagen Secretion. Cell Rep (2016) 0.89
Characteristic phenotypes associated with congenital dyserythropoietic anemia (type II) manifest at different stages of erythropoiesis. Haematologica (2013) 0.89
Cargos and genes: insights into vesicular transport from inherited human disease. J Med Genet (2007) 0.88
Absence of a red blood cell phenotype in mice with hematopoietic deficiency of SEC23B. Mol Cell Biol (2014) 0.88
New therapeutic targets in rare genetic skeletal diseases. Expert Opin Orphan Drugs (2015) 0.87
Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. PLoS One (2011) 0.86
ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex. PLoS One (2013) 0.86
A CULLINary ride across the secretory pathway: more than just secretion. Trends Cell Biol (2014) 0.86
Dyggve-Melchior-Clausen syndrome: chondrodysplasia resulting from defects in intracellular vesicle traffic. Proc Natl Acad Sci U S A (2008) 0.86
Membrane trafficking in osteoblasts and osteoclasts: new avenues for understanding and treating skeletal diseases. Traffic (2012) 0.86
Traffic jams in fish bones: ER-to-Golgi protein transport during zebrafish development. Cell Adh Migr (2011) 0.85
Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Dev Biol (2011) 0.85
Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening. PLoS One (2009) 0.84
TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats. Proc Natl Acad Sci U S A (2016) 0.84
Trafficking mechanisms of extracellular matrix macromolecules: insights from vertebrate development and human diseases. Int J Biochem Cell Biol (2013) 0.83
Tango1 spatially organizes ER exit sites to control ER export. J Cell Biol (2017) 0.83
Evidence for the involvement of the Arabidopsis SEC24A in male transmission. J Exp Bot (2011) 0.83
Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice. Sci Rep (2015) 0.81
Recurrent acute liver failure due to NBAS deficiency: phenotypic spectrum, disease mechanisms, and therapeutic concepts. J Inherit Metab Dis (2015) 0.81
Mammalian COPII coat component SEC24C is required for embryonic development in mice. J Biol Chem (2014) 0.80
Somatic overgrowth associated with homozygous mutations in both MAN1B1 and SEC23A. Cold Spring Harb Mol Case Stud (2016) 0.80
The nuclear pore complex function of Sec13 protein is required for cell survival during retinal development. J Biol Chem (2014) 0.79
Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion. J Cell Sci (2012) 0.79
Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice. Sci Rep (2016) 0.77
Matrilin-1 is essential for zebrafish development by facilitating collagen II secretion. J Biol Chem (2013) 0.77
Early stages of retinal development depend on Sec13 function. Biol Open (2013) 0.77
Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers. F1000 Biol Rep (2009) 0.76
ARCN1 Mutations Cause a Recognizable Craniofacial Syndrome Due to COPI-Mediated Transport Defects. Am J Hum Genet (2016) 0.76
Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A (2016) 0.76
How sterols regulate protein sorting and traffic. Proc Natl Acad Sci U S A (2007) 0.76
Mea6 controls VLDL transport through the coordinated regulation of COPII assembly. Cell Res (2016) 0.75
Endoplasmic Reticulum (ER) Stress and Endocrine Disorders. Int J Mol Sci (2017) 0.75
Screening of α-Tocopherol Transfer Protein Sensitive Genes in Human Hepatoma Cells (HepG2). Int J Mol Sci (2016) 0.75
CREB3L2-mediated expression of Sec23A/Sec24D is involved in hepatic stellate cell activation through ER-Golgi transport. Sci Rep (2017) 0.75
Identification of Cysteine Ubiquitylation Sites on the Sec23A Protein of the COPII Complex Required for Vesicle Formation from the ER. Open Biochem J (2017) 0.75
Bi-directional protein transport between the ER and Golgi. Annu Rev Cell Dev Biol (2004) 6.10
Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome. Nat Genet (2008) 4.68
Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell (2003) 4.23
Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle. Cell (2005) 3.96
Membrane fusion. Nat Struct Mol Biol (2008) 3.79
A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. Nat Genet (2010) 3.63
Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology (2006) 3.12
Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in Joubert syndrome. Nat Genet (2004) 3.01
Protein translocation across biological membranes. Science (2005) 2.99
Ubiquitin-dependent regulation of COPII coat size and function. Nature (2012) 2.88
Lipid homeostasis, lipotoxicity and the metabolic syndrome. Biochim Biophys Acta (2009) 2.84
Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. Nat Genet (2010) 2.74
Launching eLife, Part 1. Elife (2012) 2.72
TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites. Cell (2009) 2.58
COPII and the regulation of protein sorting in mammals. Nat Cell Biol (2011) 2.33
The genetic basis of a craniofacial disease provides insight into COPII coat assembly. Dev Cell (2007) 2.26
Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J (2002) 2.20
A novel syndrome of hypohidrosis and intellectual disability is linked to COG6 deficiency. J Med Genet (2013) 2.12
Lipoapoptosis: its mechanism and its diseases. Biochim Biophys Acta (2002) 2.10
Launching eLife, Part 2. Elife (2012) 2.04
Rapid transformation of white adipocytes into fat-oxidizing machines. Proc Natl Acad Sci U S A (2004) 2.03
Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America. Circ Res (2007) 1.97
A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway. J Cell Biol (2002) 1.93
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome. Proc Natl Acad Sci U S A (2008) 1.89
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure. Nat Cell Biol (2009) 1.80
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations. Pharmacogenetics (2002) 1.79
Paracrinology of islets and the paracrinopathy of diabetes. Proc Natl Acad Sci U S A (2010) 1.79
Diabetes and apoptosis: lipotoxicity. Apoptosis (2009) 1.75
Association between IRF6 and nonsyndromic cleft lip with or without cleft palate in four populations. Genet Med (2007) 1.75
Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3. Proc Natl Acad Sci U S A (2002) 1.73
From the Cover: STIM1-induced precortical and cortical subdomains of the endoplasmic reticulum. Proc Natl Acad Sci U S A (2009) 1.71
Coordination of COPII vesicle trafficking by Sec23. Trends Cell Biol (2008) 1.70
Ceramide biosynthesis is required for the formation of the oligomeric H+-ATPase Pma1p in the yeast endoplasmic reticulum. J Biol Chem (2002) 1.67
The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis. Elife (2013) 1.66
Reforming research assessment. Elife (2013) 1.65
UNC93B1 mediates differential trafficking of endosomal TLRs. Elife (2013) 1.61
The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane. Proc Natl Acad Sci U S A (2003) 1.58
Sec16p potentiates the action of COPII proteins to bud transport vesicles. J Cell Biol (2002) 1.55
Uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex II vesicles. J Biol Chem (2004) 1.52
Exomer: A coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast. J Cell Biol (2006) 1.52
Fat storage in adipocytes requires inactivation of leptin's paracrine activity: implications for treatment of human obesity. Proc Natl Acad Sci U S A (2005) 1.52
Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex. Dev Cell (2011) 1.50
Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor. Am J Cardiovasc Drugs (2013) 1.49
Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate. Genet Epidemiol (2011) 1.47
Determining the cause of patchwork HBA1 and HBA2 genes: recurrent gene conversion or crossing over fixation events. Haematologica (2006) 1.45
GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes. EMBO J (2004) 1.43
Microsatellite markers within --SEA breakpoints for prenatal diagnosis of HbBarts hydrops fetalis. Clin Chem (2006) 1.41
The eLife approach to peer review. Elife (2013) 1.40
Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack. Mol Biol Cell (2004) 1.39
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network. Proc Natl Acad Sci U S A (2012) 1.38
Mutations in FBXL4 cause mitochondrial encephalopathy and a disorder of mitochondrial DNA maintenance. Am J Hum Genet (2013) 1.37
LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome. Am J Hum Genet (2010) 1.37
COPII-mediated vesicle formation at a glance. J Cell Sci (2011) 1.35
Generation and characterization of telomerase-transfected human lymphatic endothelial cells with an extended life span. Am J Pathol (2004) 1.35
Interaction of Sla2p's ANTH domain with PtdIns(4,5)P2 is important for actin-dependent endocytic internalization. Mol Biol Cell (2004) 1.34
PNAS takes action regarding breach of NIH embargo policy on a PNAS paper. Proc Natl Acad Sci U S A (2009) 1.34
Structure of human cytidine deaminase bound to a potent inhibitor. J Med Chem (2005) 1.32
Biotin-responsive basal ganglia disease should be renamed biotin-thiamine-responsive basal ganglia disease: a retrospective review of the clinical, radiological and molecular findings of 18 new cases. Orphanet J Rare Dis (2013) 1.30
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum. Proc Natl Acad Sci U S A (2010) 1.29
FAT10 plays a role in the regulation of chromosomal stability. J Biol Chem (2006) 1.28
The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function. Cell Host Microbe (2007) 1.27
Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin. Diabetes (2007) 1.26
Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins. J Cell Biol (2008) 1.26
Concentrative sorting of secretory cargo proteins into COPII-coated vesicles. J Cell Biol (2002) 1.23
Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat. EMBO J (2011) 1.22
ER-Golgi transport defects are associated with mutations in the Sed5p-binding domain of the COPII coat subunit, Sec24p. Mol Biol Cell (2005) 1.21
Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria: an ultrastructural study. PLoS One (2012) 1.20
COPII-coated vesicles: flexible enough for large cargo? Curr Opin Cell Biol (2005) 1.19
In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles. Proc Natl Acad Sci U S A (2009) 1.19
SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife (2013) 1.18