Published in EMBO J on June 02, 2005
DNA topoisomerase II and its growing repertoire of biological functions. Nat Rev Cancer (2009) 3.05
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell (2008) 2.25
The SUMO-specific protease SENP5 is required for cell division. Mol Cell Biol (2006) 1.81
Purification and identification of endogenous polySUMO conjugates. EMBO Rep (2011) 1.72
SUMO: a multifaceted modifier of chromatin structure and function. Dev Cell (2013) 1.50
Emerging roles of the SUMO pathway in mitosis. Cell Div (2008) 1.48
Bub1 is essential for assembly of the functional inner centromere. J Cell Biol (2007) 1.45
Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol (2008) 1.37
SUMOylation and deSUMOylation at a glance. J Cell Sci (2009) 1.37
Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation. J Cell Biol (2006) 1.34
PIASy-mediated sumoylation of Yin Yang 1 depends on their interaction but not the RING finger. Mol Cell Biol (2007) 1.23
PIASgamma is required for faithful chromosome segregation in human cells. PLoS One (2006) 1.21
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. Mol Biol Cell (2008) 1.19
Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage. Proc Natl Acad Sci U S A (2006) 1.15
The role of SUMO in chromosome segregation. Chromosoma (2006) 1.15
Ubiquitin and SUMO systems in the regulation of mitotic checkpoints. Trends Biochem Sci (2006) 1.15
SUMOylation modulates the function of Aurora-B kinase. J Cell Sci (2010) 1.10
PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity. J Cell Biol (2010) 1.10
Developmental control of sumoylation pathway proteins in mouse male germ cells. Dev Biol (2008) 1.09
DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. Mol Biol Cell (2008) 1.09
Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H. J Clin Invest (2012) 1.04
The function of spliceosome components in open mitosis. Nucleus (2010) 1.01
Topoisomerase IIα in chromosome instability and personalized cancer therapy. Oncogene (2014) 0.97
Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier. J Biol Chem (2008) 0.96
PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes. J Biol Chem (2010) 0.95
SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer. Trends Biochem Sci (2015) 0.95
SUMOylation of the C-terminal domain of DNA topoisomerase IIα regulates the centromeric localization of Claspin. Cell Cycle (2015) 0.94
SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis. Mol Biol Cell (2013) 0.93
Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryo. Cell Rep (2013) 0.93
Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIalpha. Nucleic Acids Res (2008) 0.93
SUMOylation regulates polo-like kinase 1-interacting checkpoint helicase (PICH) during mitosis. J Biol Chem (2015) 0.92
Rod/Zw10 complex is required for PIASy-dependent centromeric SUMOylation. J Biol Chem (2010) 0.91
SUMOylation in control of accurate chromosome segregation during mitosis. Curr Protein Pept Sci (2012) 0.89
SUMO modification of DNA topoisomerase II: trying to get a CENse of it all. DNA Repair (Amst) (2009) 0.89
Phosphorylation of Ubc9 by Cdk1 enhances SUMOylation activity. PLoS One (2012) 0.89
Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei. Nucleic Acids Res (2010) 0.88
The SUMO pathway functions in mouse oocyte maturation. Cell Cycle (2010) 0.87
Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol (2011) 0.87
Identification of protein SUMOylation sites by mass spectrometry using combined microwave-assisted aspartic acid cleavage and tryptic digestion. J Mass Spectrom (2012) 0.86
SUMOylation of DNA topoisomerase IIα regulates histone H3 kinase Haspin and H3 phosphorylation in mitosis. J Cell Biol (2016) 0.85
A noncatalytic function of the topoisomerase II CTD in Aurora B recruitment to inner centromeres during mitosis. J Cell Biol (2016) 0.84
The fate of metaphase kinetochores is weighed in the balance of SUMOylation during S phase. Cell Cycle (2010) 0.84
Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans. Nat Commun (2014) 0.82
Comprehensive identification of SUMO2/3 targets and their dynamics during mitosis. PLoS One (2014) 0.82
Reprogramming to pluripotency can conceal somatic cell chromosomal instability. PLoS Genet (2012) 0.82
The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci. J Cell Sci (2012) 0.79
SUMOylation of Psmd1 controls Adrm1 interaction with the proteasome. Cell Rep (2014) 0.77
Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response. J Virol (2016) 0.76
The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation. J Biol Chem (2016) 0.75
The SUMO deconjugating peptidase Smt4 contributes to the mechanism required for transition from sister chromatid arm cohesion to sister chromatid pericentromere separation. Cell Cycle (2015) 0.75
Protein modification by SUMO. Annu Rev Biochem (2004) 10.59
Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell (2003) 9.90
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev (2001) 5.79
The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol (1999) 4.31
SAP - a putative DNA-binding motif involved in chromosomal organization. Trends Biochem Sci (2000) 4.10
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. Cell (2002) 4.09
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A (2005) 3.62
Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science (2001) 3.35
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev (2003) 3.04
Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif. J Biol Chem (2000) 3.01
SUMO: ligases, isopeptidases and nuclear pores. Trends Biochem Sci (2003) 2.92
The genetics of position-effect variegation modifying loci in Drosophila melanogaster. Mol Gen Genet (1989) 2.90
The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell (2002) 2.85
SUMO-2/3 regulates topoisomerase II in mitosis. J Cell Biol (2003) 2.24
SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell (2001) 2.23
Distinct in vivo dynamics of vertebrate SUMO paralogues. Mol Biol Cell (2004) 2.14
The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family. Genes Dev (2001) 1.90
The Ran GTPase regulates kinetochore function. Dev Cell (2003) 1.73
Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance. EMBO J (2004) 1.25
Expression and regulation of the mammalian SUMO-1 E1 enzyme. FASEB J (2001) 1.25
Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life. Mol Cell Biol (2004) 1.24
NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers. J Biol Chem (2004) 1.23
Quantitation of type II topoisomerase in oocytes and eggs of Xenopus laevis. Dev Biol (1989) 1.17
Modification of GATA-2 transcriptional activity in endothelial cells by the SUMO E3 ligase PIASy. Circ Res (2003) 1.07
Modification in reverse: the SUMO proteases. Trends Biochem Sci (2007) 3.84
The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo. Curr Biol (2004) 2.88
SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. J Cell Biol (2002) 2.60
Crm1 is a mitotic effector of Ran-GTP in somatic cells. Nat Cell Biol (2005) 2.56
Association of the human SUMO-1 protease SENP2 with the nuclear pore. J Biol Chem (2002) 2.33
SUMO-2/3 regulates topoisomerase II in mitosis. J Cell Biol (2003) 2.24
Distinct in vivo dynamics of vertebrate SUMO paralogues. Mol Biol Cell (2004) 2.14
Nucleoporin levels regulate cell cycle progression and phase-specific gene expression. Dev Cell (2008) 2.00
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. Mol Biol Cell (2006) 1.93
The small GTPase Ran: interpreting the signs. Curr Opin Cell Biol (2003) 1.82
The Ran GTPase regulates kinetochore function. Dev Cell (2003) 1.73
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J Cell Biol (2006) 1.67
Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response. J Biol Chem (2001) 1.62
The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores. Nat Cell Biol (2010) 1.50
Bub1 is essential for assembly of the functional inner centromere. J Cell Biol (2007) 1.45
SUMOylation and deSUMOylation at a glance. J Cell Sci (2009) 1.37
Distribution and paralogue specificity of mammalian deSUMOylating enzymes. Biochem J (2010) 1.33
Xenopus HJURP and condensin II are required for CENP-A assembly. J Cell Biol (2011) 1.29
Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation. PLoS One (2009) 1.27
The SUMO protease SENP6 is essential for inner kinetochore assembly. J Cell Biol (2010) 1.21
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. J Cell Biol (2008) 1.18
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation. Genome Res (2013) 1.08
The nucleoporin Nup358 associates with and regulates interphase microtubules. FEBS Lett (2007) 1.08
Ran-GTP regulates kinetochore attachment in somatic cells. Cell Cycle (2005) 1.07
Nuclear envelope breakdown is coordinated by both Nup358/RanBP2 and Nup153, two nucleoporins with zinc finger modules. Mol Biol Cell (2005) 1.06
Plant-specific mitotic targeting of RanGAP requires a functional WPP domain. Plant J (2005) 0.95
PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes. J Biol Chem (2010) 0.95
SUMOylation of the C-terminal domain of DNA topoisomerase IIα regulates the centromeric localization of Claspin. Cell Cycle (2015) 0.94
Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryo. Cell Rep (2013) 0.93
Vesicular stomatitis virus inhibits mitotic progression and triggers cell death. EMBO Rep (2009) 0.92
Management of undifferentiated sarcoma of the liver including living donor liver transplantation as a backup procedure. J Pediatr Surg (2009) 0.91
Potential roles of the nucleotide exchange factor ECT2 and Cdc42 GTPase in spindle assembly in Xenopus egg cell-free extracts. J Cell Biochem (2003) 0.90
Identification and developmental expression of Xenopus laevis SUMO proteases. PLoS One (2009) 0.90
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2. Nucleus (2012) 0.89
SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation. Cell Rep (2013) 0.88
A new clue at the nuclear pore: RanBP2 is an E3 enzyme for SUMO1. Dev Cell (2002) 0.86
Ran GTPase regulates Mad2 localization to the nuclear pore complex. Eukaryot Cell (2005) 0.86
The fate of metaphase kinetochores is weighed in the balance of SUMOylation during S phase. Cell Cycle (2010) 0.84
Nationwide survey of bisphosphonate therapy for children with reactivated Langerhans cell histiocytosis in Japan. Pediatr Blood Cancer (2011) 0.83
Nuclear transport erupts on the slopes of Mount Etna. Nat Cell Biol (2004) 0.83
Transumbilical defunctioning ileostomy: A new approach for patients at risks of anastomotic leakage after laparoscopic low anterior resection. Anticancer Res (2013) 0.83
An ent-kaurene that inhibits mitotic chromosome movement and binds the kinetochore protein ran-binding protein 2. ACS Chem Biol (2006) 0.82
The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function. Mol Biol Cell (2013) 0.81
Cell biology: new cog for a familiar machine. Nature (2005) 0.81
Biochemistry: Rear view of an enzyme. Nature (2013) 0.78
Feasibility study of S-1 adjuvant chemotherapy in patients with colorectal cancer. Int J Clin Oncol (2012) 0.77
Blood transfusion requirement for gastric cancer surgery: reasonable preparation for transfusion in the comprehensive health insurance system. Int J Surg (2008) 0.75
A comparison of laparoscopic energy devices on charges in thermal power after application to porcine mesentery. Surg Laparosc Endosc Percutan Tech (2015) 0.75
Heterochronous bilateral adrenal neuroblastoma: stage 4S in early infancy following resection of stage I lesion in the neonatal period. Pediatr Surg Int (2012) 0.75