Published in J Cell Biol on November 17, 2008
Function and regulation of SUMO proteases. Nat Rev Mol Cell Biol (2012) 2.55
Nucleolar targeting: the hub of the matter. EMBO Rep (2009) 1.82
Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. Mol Cell (2010) 1.50
SUMO: a multifaceted modifier of chromatin structure and function. Dev Cell (2013) 1.50
NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin Remodeling. Biochem Res Int (2010) 1.49
SUMOylation and deSUMOylation at a glance. J Cell Sci (2009) 1.37
Distribution and paralogue specificity of mammalian deSUMOylating enzymes. Biochem J (2010) 1.33
The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. EMBO J (2011) 1.24
LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis. Mol Biol Cell (2011) 1.03
A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58. Mol Cell (2010) 0.97
The Nucleolus Takes Control of Protein Trafficking Under Cellular Stress. Mol Cell Pharmacol (2010) 0.95
SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis. Mol Biol Cell (2013) 0.93
Nucleophosmin/B23 regulates ubiquitin dynamics in nucleoli by recruiting deubiquitylating enzyme USP36. J Biol Chem (2009) 0.92
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies. Mol Biol Cell (2010) 0.91
Identification and developmental expression of Xenopus laevis SUMO proteases. PLoS One (2009) 0.90
SUMOylation in control of accurate chromosome segregation during mitosis. Curr Protein Pept Sci (2012) 0.89
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2. Nucleus (2012) 0.89
The SUMO system: a master organizer of nuclear protein assemblies. Chromosoma (2013) 0.88
Starting and stopping SUMOylation. What regulates the regulator? Chromosoma (2013) 0.88
Nucleophosmin deposition during mRNA 3' end processing influences poly(A) tail length. EMBO J (2011) 0.88
Environmental cues induce a long noncoding RNA-dependent remodeling of the nucleolus. Mol Biol Cell (2013) 0.87
Ubiquitin and ubiquitin-like proteins in the nucleolus: multitasking tools for a ribosome factory. Genes Cancer (2010) 0.86
SUMO-specific proteases/isopeptidases: SENPs and beyond. Genome Biol (2014) 0.85
Nucleolar localization and identification of nuclear/nucleolar localization signals of the calmodulin-binding protein nucleomorphin during growth and mitosis in Dictyostelium. Histochem Cell Biol (2011) 0.82
Fine-tuning nucleophosmin in macrophage differentiation and activation. Blood (2011) 0.82
The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function. Mol Biol Cell (2013) 0.81
De-SUMOylation of CCCTC binding factor (CTCF) in hypoxic stress-induced human corneal epithelial cells. J Biol Chem (2012) 0.81
Nucleoplasmic/nucleolar translocation and identification of a nuclear localization signal (NLS) in Dictyostelium BAF60a/SMARCD1 homologue Snf12. Histochem Cell Biol (2012) 0.79
The SUMO Protease SENP3 Orchestrates G2-M Transition and Spindle Assembly in Mouse Oocytes. Sci Rep (2015) 0.78
mTOR signaling regulates nucleolar targeting of the SUMO-specific isopeptidase SENP3. Mol Cell Biol (2014) 0.78
SUMOylation Confers Posttranslational Stability on NPM-ALK Oncogenic Protein. Neoplasia (2015) 0.76
Flightless-I governs cell fate by recruiting the SUMO isopeptidase SENP3 to distinct HOX genes. Epigenetics Chromatin (2017) 0.75
Domain analysis of the Nematostella vectensis SNAIL ortholog reveals unique nucleolar localization that depends on the zinc-finger domains. Sci Rep (2015) 0.75
Mutation of the N-Terminal Region of Chikungunya Virus Capsid Protein: Implications for Vaccine Design. MBio (2017) 0.75
Protein modification by SUMO. Annu Rev Biochem (2004) 10.59
SUMO: a history of modification. Mol Cell (2005) 10.40
The multifunctional nucleolus. Nat Rev Mol Cell Biol (2007) 7.08
A new protease required for cell-cycle progression in yeast. Nature (1999) 5.44
Divorcing ARF and p53: an unsettled case. Nat Rev Cancer (2006) 5.17
Nucleophosmin and cancer. Nat Rev Cancer (2006) 4.82
SUMO-1 modification activates the transcriptional response of p53. EMBO J (1999) 4.19
Modification in reverse: the SUMO proteases. Trends Biochem Sci (2007) 3.84
Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem (2004) 3.53
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Mol Cell (2003) 3.42
The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol Cell Biol (2000) 3.24
Global analysis of protein sumoylation in Saccharomyces cerevisiae. J Biol Chem (2004) 2.60
A proteomic strategy for gaining insights into protein sumoylation in yeast. Mol Cell Proteomics (2004) 2.58
SUMO-specific proteases: a twist in the tail. Trends Cell Biol (2007) 2.50
A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem (2004) 2.31
SUMO-2/3 regulates topoisomerase II in mitosis. J Cell Biol (2003) 2.24
Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. J Biol Chem (2006) 2.15
Distinct in vivo dynamics of vertebrate SUMO paralogues. Mol Biol Cell (2004) 2.14
Nucleolar protein B23 has molecular chaperone activities. Protein Sci (1999) 2.07
Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonuclease. Nucleic Acids Res (1998) 2.06
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. Mol Biol Cell (2006) 1.93
The SUMO-specific protease SENP5 is required for cell division. Mol Cell Biol (2006) 1.81
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep (2008) 1.47
Bub1 is essential for assembly of the functional inner centromere. J Cell Biol (2007) 1.45
Formation and nuclear export of preribosomes are functionally linked to the small-ubiquitin-related modifier pathway. Traffic (2006) 1.27
Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival. Proc Natl Acad Sci U S A (2007) 1.22
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem (2009) 6.23
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains. EMBO Rep (2009) 3.94
Modification in reverse: the SUMO proteases. Trends Biochem Sci (2007) 3.84
The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin. Cell (2006) 3.46
Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family. Chem Biol (2002) 3.43
Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. EMBO J (2005) 2.99
The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo. Curr Biol (2004) 2.88
BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization. Cancer Res (2008) 2.81
SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. J Cell Biol (2002) 2.60
Crm1 is a mitotic effector of Ran-GTP in somatic cells. Nat Cell Biol (2005) 2.56
Association of the human SUMO-1 protease SENP2 with the nuclear pore. J Biol Chem (2002) 2.33
SUMO-2/3 regulates topoisomerase II in mitosis. J Cell Biol (2003) 2.24
Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function. J Biol Chem (2003) 2.21
Protein partners of deubiquitinating enzymes. Biochem J (2008) 2.15
Distinct in vivo dynamics of vertebrate SUMO paralogues. Mol Biol Cell (2004) 2.14
Nucleoporin levels regulate cell cycle progression and phase-specific gene expression. Dev Cell (2008) 2.00
De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila. Science (2011) 1.98
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. Mol Biol Cell (2006) 1.93
Hsp70 chaperones as modulators of prion life cycle: novel effects of Ssa and Ssb on the Saccharomyces cerevisiae prion [PSI+]. Genetics (2004) 1.90
Poly(gamma-D-glutamic acid) protein conjugates induce IgG antibodies in mice to the capsule of Bacillus anthracis: a potential addition to the anthrax vaccine. Proc Natl Acad Sci U S A (2003) 1.87
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins. Mol Cell Biol (2004) 1.86
Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1. J Mol Biol (2009) 1.82
The small GTPase Ran: interpreting the signs. Curr Opin Cell Biol (2003) 1.82
Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein. J Biol Chem (2008) 1.75
The Ran GTPase regulates kinetochore function. Dev Cell (2003) 1.73
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1. J Biol Chem (2003) 1.72
Pleiotropic effects of Ubp6 loss on drug sensitivities and yeast prion are due to depletion of the free ubiquitin pool. J Biol Chem (2003) 1.69
Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. Cancer Res (2005) 1.69
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J Cell Biol (2006) 1.67
Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T. J Biol Chem (2008) 1.64
Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells. Oncogene (2005) 1.64
PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes. EMBO J (2005) 1.62
Identification and characterization of DEN1, a deneddylase of the ULP family. J Biol Chem (2003) 1.62
The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores. Nat Cell Biol (2010) 1.50
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proc Natl Acad Sci U S A (2009) 1.49
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat (2006) 1.49
A newly discovered cholesteryl galactoside from Borrelia burgdorferi. Proc Natl Acad Sci U S A (2003) 1.48
Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21. EMBO Rep (2011) 1.47
Bub1 is essential for assembly of the functional inner centromere. J Cell Biol (2007) 1.45
Regulation of proteolysis by human deubiquitinating enzymes. Biochim Biophys Acta (2013) 1.42
Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63. J Virol (2007) 1.39
Doa1 is a Cdc48 adapter that possesses a novel ubiquitin binding domain. Mol Cell Biol (2006) 1.39
SUMOylation and deSUMOylation at a glance. J Cell Sci (2009) 1.37
Polyubiquitin binding and disassembly by deubiquitinating enzymes. Chem Rev (2009) 1.36
Distribution and paralogue specificity of mammalian deSUMOylating enzymes. Biochem J (2010) 1.33
An emerging model for BAP1's role in regulating cell cycle progression. Cell Biochem Biophys (2011) 1.30
Xenopus HJURP and condensin II are required for CENP-A assembly. J Cell Biol (2011) 1.29
Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1. J Mol Biol (2005) 1.28
Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation. PLoS One (2009) 1.27
Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities. Protein Sci (2008) 1.26
Effects of ubiquitin system alterations on the formation and loss of a yeast prion. J Biol Chem (2006) 1.26
Phosphate stabilization of intermolecular interactions. J Proteome Res (2006) 1.25
Prion induction by the short-lived, stress-induced protein Lsb2 is regulated by ubiquitination and association with the actin cytoskeleton. Mol Cell (2011) 1.24
Derivitization of the C-terminus of ubiquitin and ubiquitin-like proteins using intein chemistry: methods and uses. Methods Enzymol (2005) 1.23
The SUMO protease SENP6 is essential for inner kinetochore assembly. J Cell Biol (2010) 1.21
Haplotypes in matrix metalloproteinase gene cluster on chromosome 11q22 contribute to the risk of lung cancer development and progression. Clin Cancer Res (2006) 1.16
Twisting carbon nanotube fibers for both wire-shaped micro-supercapacitor and micro-battery. Adv Mater (2012) 1.12
Structure and recognition of polyubiquitin chains of different lengths and linkage. F1000 Biol Rep (2011) 1.08
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation. Genome Res (2013) 1.08
The nucleoporin Nup358 associates with and regulates interphase microtubules. FEBS Lett (2007) 1.08
Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes). Biochem J (2008) 1.08
Ran-GTP regulates kinetochore attachment in somatic cells. Cell Cycle (2005) 1.07
Nuclear envelope breakdown is coordinated by both Nup358/RanBP2 and Nup153, two nucleoporins with zinc finger modules. Mol Biol Cell (2005) 1.06
Functional STK15 Phe31Ile polymorphism is associated with the occurrence and advanced disease status of esophageal squamous cell carcinoma. Cancer Res (2004) 1.04
DNA repair gene XPC genotypes/haplotypes and risk of lung cancer in a Chinese population. Int J Cancer (2005) 1.03
Burkholderia mallei tssM encodes a putative deubiquitinase that is secreted and expressed inside infected RAW 264.7 murine macrophages. Infect Immun (2009) 1.03
Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis (2005) 1.02
A rapid LC/MS/MS quantitation assay for naringin and its two metabolites in rats plasma. J Pharm Biomed Anal (2006) 1.01
Deubiquitinating enzyme purification, assay inhibitors, and characterization. Methods Mol Biol (2005) 1.00
Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. Toxicol Lett (2013) 0.99
Physiological and environmental control of yeast prions. FEMS Microbiol Rev (2013) 0.97
Identification of a novel 29-linked polyubiquitin binding protein, Ufd3, using polyubiquitin chain analogues. Biochemistry (2004) 0.97
Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2. Cardiovasc Diabetol (2013) 0.97
Anti-diarrhoea and analgesic activities of the methanol extract and its fractions of Jasminum amplexicaule Buch.-Ham. (Oleaceae). J Ethnopharmacol (2008) 0.96
Plant-specific mitotic targeting of RanGAP requires a functional WPP domain. Plant J (2005) 0.95
PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes. J Biol Chem (2010) 0.95
Assessing gait impairment following experimental traumatic brain injury in mice. J Neurosci Methods (2008) 0.95
Hepatoprotective effect of Hypericum japonicum extract and its fractions. J Ethnopharmacol (2007) 0.94
SUMOylation of the C-terminal domain of DNA topoisomerase IIα regulates the centromeric localization of Claspin. Cell Cycle (2015) 0.94
A novel in vivo model of human hemangioma: xenograft of human hemangioma tissue on nude mice. Plast Reconstr Surg (2007) 0.93
Targeting JNK by a new curcumin analog to inhibit NF-kB-mediated expression of cell adhesion molecules attenuates renal macrophage infiltration and injury in diabetic mice. PLoS One (2013) 0.93
Two ZnF-UBP domains in isopeptidase T (USP5). Biochemistry (2012) 0.93
The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex. Mol Biol Cell (2011) 0.93
Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryo. Cell Rep (2013) 0.93
Vesicular stomatitis virus inhibits mitotic progression and triggers cell death. EMBO Rep (2009) 0.92
Dynamic compartmentalization of base excision repair proteins in response to nuclear and mitochondrial oxidative stress. Mol Cell Biol (2008) 0.91
Potential roles of the nucleotide exchange factor ECT2 and Cdc42 GTPase in spindle assembly in Xenopus egg cell-free extracts. J Cell Biochem (2003) 0.90
Identification and developmental expression of Xenopus laevis SUMO proteases. PLoS One (2009) 0.90
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2. Nucleus (2012) 0.89
Rechargeable Ni-Li battery integrated aqueous/nonaqueous system. J Am Chem Soc (2009) 0.89
Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity. J Neurochem (2004) 0.89