Published in Am J Physiol Lung Cell Mol Physiol on June 03, 2005
Motile cilia of human airway epithelia are chemosensory. Science (2009) 4.40
Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome? Am J Respir Cell Mol Biol (2010) 1.40
WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung. Respir Res (2006) 1.39
Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease. Am J Respir Cell Mol Biol (2006) 1.39
Chemosensory functions for pulmonary neuroendocrine cells. Am J Respir Cell Mol Biol (2014) 1.06
Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling. J Lipid Res (2009) 0.99
New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis. PLoS One (2009) 0.88
Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions. Free Radic Biol Med (2011) 0.86
Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies. Respir Res (2013) 0.85
SERCA2 regulates non-CF and CF airway epithelial cell response to ozone. PLoS One (2011) 0.84
A novel approach to analyze gene expression data demonstrates that the DeltaF508 mutation in CFTR downregulates the antigen presentation pathway. Am J Physiol Lung Cell Mol Physiol (2009) 0.82
Omics approaches in cystic fibrosis research: a focus on oxylipin profiling in airway secretions. Ann N Y Acad Sci (2012) 0.81
Cystic fibrosis remodels the regulation of purinergic signaling by NTPDase1 (CD39) and NTPDase3. Am J Physiol Lung Cell Mol Physiol (2010) 0.79
In silico search for modifier genes associated with pancreatic and liver disease in Cystic Fibrosis. PLoS One (2017) 0.75
Transcriptomic profile of cystic fibrosis patients identifies type I interferon response and ribosomal stalk proteins as potential modifiers of disease severity. PLoS One (2017) 0.75
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A (2002) 20.48
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst (2008) 11.93
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell (2008) 11.24
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res (2004) 9.18
Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science (2008) 6.28
International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant (2006) 4.95
Solitary fibrous tumors of the pleura. Ann Thorac Surg (2002) 4.78
The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups. J Thorac Cardiovasc Surg (2012) 4.68
COORDINATE DESCENT ALGORITHMS FOR NONCONVEX PENALIZED REGRESSION, WITH APPLICATIONS TO BIOLOGICAL FEATURE SELECTION. Ann Appl Stat (2011) 4.18
Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc Natl Acad Sci U S A (2006) 4.16
Normothermic ex vivo lung perfusion in clinical lung transplantation. N Engl J Med (2011) 3.87
Comprehensive genetic testing for hereditary hearing loss using massively parallel sequencing. Proc Natl Acad Sci U S A (2010) 3.85
A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph node staging of lung cancer. J Thorac Cardiovasc Surg (2011) 3.76
Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Res (2002) 3.68
Current prospects for RNA interference-based therapies. Nat Rev Genet (2011) 3.63
Ischemia-reperfusion-induced lung injury. Am J Respir Crit Care Med (2003) 3.54
Is video-assisted lobectomy for non-small-cell lung cancer oncologically equivalent to open lobectomy? Eur J Cardiothorac Surg (2013) 3.49
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Sci Transl Med (2010) 3.36
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell (2011) 3.27
A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Dev Cell (2008) 3.17
Missense variations in the fibulin 5 gene and age-related macular degeneration. N Engl J Med (2004) 3.15
Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature (2012) 2.96
Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Nature (2011) 2.94
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature (2012) 2.94
Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers. J Clin Oncol (2010) 2.93
Regulation of gene expression in the mammalian eye and its relevance to eye disease. Proc Natl Acad Sci U S A (2006) 2.91
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα. Cell (2013) 2.87
Ribonucleic acid microarray analysis from lymph node samples obtained by endobronchial ultrasonography-guided transbronchial needle aspiration. Ann Thorac Surg (2012) 2.63
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res (2013) 2.63
A novel host defense system of airways is defective in cystic fibrosis. Am J Respir Crit Care Med (2006) 2.61
Discovery of five conserved beta -defensin gene clusters using a computational search strategy. Proc Natl Acad Sci U S A (2002) 2.56
The porcine lung as a potential model for cystic fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 2.53
Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair. Genes Dev (2005) 2.47
Cytokine-mediated regulation of antimicrobial proteins. Nat Rev Immunol (2008) 2.46
Prevalence of gastroesophageal reflux in end-stage lung disease candidates for lung transplant. Ann Thorac Surg (2005) 2.41
Regularized ROC method for disease classification and biomarker selection with microarray data. Bioinformatics (2005) 2.38
Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome. J Virol (2007) 2.35
Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed. J Clin Invest (2008) 2.21
MicroRNA expression profiling of esophageal cancer before and after induction chemoradiotherapy. Ann Thorac Surg (2012) 2.20
The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus. J Biol Chem (2001) 2.20
Rapid generation of a mouse model for Middle East respiratory syndrome. Proc Natl Acad Sci U S A (2014) 2.17
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus. Proc Natl Acad Sci U S A (2011) 2.12
Three-gene prognostic classifier for early-stage non small-cell lung cancer. J Clin Oncol (2007) 2.10
MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data. Nucleic Acids Res (2012) 2.09
The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Sci Transl Med (2011) 2.01
Supervised group Lasso with applications to microarray data analysis. BMC Bioinformatics (2007) 1.99
Soybean WRKY-type transcription factor genes, GmWRKY13, GmWRKY21, and GmWRKY54, confer differential tolerance to abiotic stresses in transgenic Arabidopsis plants. Plant Biotechnol J (2008) 1.98
Clustering threshold gradient descent regularization: with applications to microarray studies. Bioinformatics (2006) 1.97
Laparoendoscopic single-site nephrectomy compared with conventional laparoscopic nephrectomy: a systematic review and meta-analysis of comparative studies. Eur Urol (2012) 1.96
Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A. J Hepatol (2008) 1.95
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children. Am J Respir Crit Care Med (2010) 1.94
Ebola virus glycoprotein 1: identification of residues important for binding and postbinding events. J Virol (2007) 1.93
Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms. J Clin Microbiol (2004) 1.91
Correlation between beta-defensin expression and induction profiles in gingival keratinocytes. Mol Immunol (2004) 1.90
Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse. Proc Natl Acad Sci U S A (2004) 1.88
Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa. Proc Natl Acad Sci U S A (2011) 1.87
A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice. Cancer Res (2009) 1.86
Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration. Invest Ophthalmol Vis Sci (2011) 1.85
Antimicrobial peptides in animals and their role in host defences. Int J Antimicrob Agents (2003) 1.84
Penalized methods for bi-level variable selection. Stat Interface (2009) 1.82
Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis. Proc Natl Acad Sci U S A (2010) 1.82
Bile acid aspiration and the development of bronchiolitis obliterans after lung transplantation. J Thorac Cardiovasc Surg (2005) 1.81
[beta]-defensins in lung host defense. Annu Rev Physiol (2002) 1.80
Cell of origin strongly influences genetic selection in a mouse model of T-ALL. Blood (2011) 1.78
Technique for prolonged normothermic ex vivo lung perfusion. J Heart Lung Transplant (2008) 1.77
Toll-like receptors in inflammation, infection and cancer. Int Immunopharmacol (2007) 1.76
Neuroendocrine carcinoma (carcinoid) of the thymus associated with Cushing's syndrome. Ann Thorac Surg (2002) 1.74
Copy number variations on chromosome 12q14 in patients with normal tension glaucoma. Hum Mol Genet (2011) 1.74
Experience with the first 50 ex vivo lung perfusions in clinical transplantation. J Thorac Cardiovasc Surg (2012) 1.73
Organ donor management in Canada: recommendations of the forum on Medical Management to Optimize Donor Organ Potential. CMAJ (2006) 1.73
Restrictive allograft syndrome (RAS): a novel form of chronic lung allograft dysfunction. J Heart Lung Transplant (2011) 1.73
T cell factor 1 is required for group 2 innate lymphoid cell generation. Immunity (2013) 1.72
Functional repair of human donor lungs by IL-10 gene therapy. Sci Transl Med (2009) 1.72
Combining multiple markers for classification using ROC. Biometrics (2007) 1.72
MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3. Int J Cancer (2011) 1.70
Interleukin-8 release during early reperfusion predicts graft function in human lung transplantation. Am J Respir Crit Care Med (2002) 1.69
Advancing genetic testing for deafness with genomic technology. J Med Genet (2013) 1.66
Chemical ablation of the Purkinje system causes early termination and activation rate slowing of long-duration ventricular fibrillation in dogs. Am J Physiol Heart Circ Physiol (2008) 1.66
Differential gene profiling in acute lung injury identifies injury-specific gene expression. Crit Care Med (2008) 1.65
Insights into a dinoflagellate genome through expressed sequence tag analysis. BMC Genomics (2005) 1.65
Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2. Am J Physiol Lung Cell Mol Physiol (2004) 1.64
Regularized gene selection in cancer microarray meta-analysis. BMC Bioinformatics (2009) 1.64
Cell-based tissue engineering for lung regeneration. Am J Physiol Lung Cell Mol Physiol (2006) 1.63
Utility of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal masses of unknown etiology. Ann Thorac Surg (2011) 1.63
Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women. Int J Cancer (2009) 1.63
Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. Dev Biol (2004) 1.62
The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia. Am J Physiol Lung Cell Mol Physiol (2010) 1.61
Myosin light chain kinase and myosin phosphorylation effect frequency-dependent potentiation of skeletal muscle contraction. Proc Natl Acad Sci U S A (2005) 1.59
Definition of the landscape of promoter DNA hypomethylation in liver cancer. Cancer Res (2011) 1.58