Published in Radiat Res on July 01, 2005
Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements. Nano Lett (2006) 1.63
Assessing the risk of second malignancies after modern radiotherapy. Nat Rev Cancer (2011) 1.55
Molecular characterization of the cytotoxic mechanism of multiwall carbon nanotubes and nano-onions on human skin fibroblast. Nano Lett (2005) 1.53
Global gene expression analyses of bystander and alpha particle irradiated normal human lung fibroblasts: synchronous and differential responses. BMC Med Genomics (2008) 1.22
Functional genomics in radiation biology: a gateway to cellular systems-level studies. Radiat Environ Biophys (2007) 1.18
Low dose radiation adaptive protection to control neurodegenerative diseases. Dose Response (2013) 1.16
Heavy ion radiation exposure triggered higher intestinal tumor frequency and greater β-catenin activation than γ radiation in APC(Min/+) mice. PLoS One (2013) 1.03
Micro RNA responses to chronic or acute exposures to low dose ionizing radiation. Mol Biol Rep (2012) 1.01
Induced expression of the IER5 gene by gamma-ray irradiation and its involvement in cell cycle checkpoint control and survival. Radiat Environ Biophys (2009) 0.97
Increased frequency of spontaneous neoplastic transformation in progeny of bystander cells from cultures exposed to densely ionizing radiation. PLoS One (2011) 0.93
Gene expression arrays as a tool to unravel mechanisms of normal tissue radiation injury and prediction of response. World J Gastroenterol (2007) 0.91
Transient genome-wide transcriptional response to low-dose ionizing radiation in vivo in humans. Int J Radiat Oncol Biol Phys (2007) 0.90
Development of a zebrafish spleen cell line, ZSSJ, and its growth arrest by gamma irradiation and capacity to act as feeder cells. In Vitro Cell Dev Biol Anim (2008) 0.89
Identification of gene expression biomarkers for predicting radiation exposure. Sci Rep (2014) 0.89
Global gene expression responses to low- or high-dose radiation in a human three-dimensional tissue model. Radiat Res (2011) 0.88
Phosphoproteomics profiling of human skin fibroblast cells reveals pathways and proteins affected by low doses of ionizing radiation. PLoS One (2010) 0.87
Very large amounts of radiation are required to produce cancer. Dose Response (2007) 0.87
Radio-adaptive response to environmental exposures at Chernobyl. Dose Response (2008) 0.87
Differential gene expression in primary human skin keratinocytes and fibroblasts in response to ionizing radiation. Radiat Res (2009) 0.87
Distinct transcriptome profiles identified in normal human bronchial epithelial cells after exposure to γ-rays and different elemental particles of high Z and energy. BMC Genomics (2013) 0.85
Comparison of low and high dose ionising radiation using topological analysis of gene coexpression networks. BMC Genomics (2012) 0.84
Transcriptional response of ex vivo human skin to ionizing radiation: comparison between low- and high-dose effects. Radiat Res (2011) 0.84
mRNA Expression Profiles for Prostate Cancer following Fractionated Irradiation Are Influenced by p53 Status. Transl Oncol (2013) 0.84
Molecular biology: the key to personalised treatment in radiation oncology? Br J Radiol (2010) 0.84
Effects of DNA-targeted ionizing radiation produced by 5-[125I]iodo-2'-deoxyuridine on global gene expression in primary human cells. BMC Genomics (2007) 0.83
Effects of low doses of ionizing radiation exposures on stress-responsive gene expression in human embryonic stem cells. Int J Mol Sci (2014) 0.82
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. Proteomics (2009) 0.81
Functional Genomics and a New Era in Radiation Biology and Oncology. Bioscience (2008) 0.81
Genomic characterization of a three-dimensional skin model following exposure to ionizing radiation. J Radiat Res (2012) 0.81
The role of dose rate in radiation cancer risk: evaluating the effect of dose rate at the molecular, cellular and tissue levels using key events in critical pathways following exposure to low LET radiation. Int J Radiat Biol (2016) 0.80
The dose and dose-rate effects of paternal irradiation on transgenerational instability in mice: a radiotherapy connection. PLoS One (2012) 0.80
Extremely low doses of X-radiation can induce adaptive responses in mouse prostate. Dose Response (2007) 0.80
Gene profiling characteristics of radioadaptive response in AG01522 normal human fibroblasts. PLoS One (2015) 0.79
Single-cell responses to ionizing radiation. Radiat Environ Biophys (2013) 0.79
Modeling cell response to low doses of photon irradiation: Part 2-application to radiation-induced chromosomal aberrations in human carcinoma cells. Radiat Environ Biophys (2015) 0.78
Combined haploinsufficiency and genetic control of the G2/M checkpoint in irradiated cells. Radiat Res (2012) 0.78
Comparative Analysis of Whole-Genome Gene Expression Changes in Cultured Human Embryonic Stem Cells in Response to Low, Clinical Diagnostic Relevant, and High Doses of Ionizing Radiation Exposure. Int J Mol Sci (2015) 0.77
Global Gene Expression Alterations as a Crucial Constituent of Human Cell Response to Low Doses of Ionizing Radiation Exposure. Int J Mol Sci (2015) 0.77
Donor-specific cell-based assays in studying sensitivity to low-dose radiation: a population-based perspective. Front Public Health (2014) 0.77
Mitigating effects of L-selenomethionine on low-dose iron ion radiation-induced changes in gene expression associated with cellular stress. Oncol Lett (2013) 0.76
MnSOD downregulation induced by extremely low 0.1 mGy single and fractionated X-rays and microgravity treatment in human neuroblastoma cell line, NB-1. J Clin Biochem Nutr (2015) 0.76
Correcting systemic deficiencies in our scientific infrastructure. Dose Response (2013) 0.75
Early Cellular Response to Radiation in Human Vocal Fold Fibroblasts. Ann Otol Rhinol Laryngol (2015) 0.75
Differential Molecular Stress Responses to Low Compared to High Doses of Ionizing Radiation in Normal Human Fibroblasts. Dose Response (2015) 0.75
LNT: a never-ending story. Radiat Environ Biophys (2006) 0.75
Radioresistance of GGG sequences to prompt strand break formation from direct-type radiation damage. Radiat Environ Biophys (2016) 0.75
Radiation-induced translational control of gene expression. Translation (Austin) (2016) 0.75
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell (2006) 16.05
A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea. Nature (2009) 15.06
Dicer, Drosha, and outcomes in patients with ovarian cancer. N Engl J Med (2008) 8.77
Insights into the phylogeny and coding potential of microbial dark matter. Nature (2013) 8.55
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell (2004) 6.48
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet (2004) 5.64
The Arabidopsis lyrata genome sequence and the basis of rapid genome size change. Nat Genet (2011) 4.65
Genomic instability in laminopathy-based premature aging. Nat Med (2005) 4.54
Assembling the marine metagenome, one cell at a time. PLoS One (2009) 4.10
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev (2002) 3.83
One bacterial cell, one complete genome. PLoS One (2010) 3.69
Complete genome sequence of Kytococcus sedentarius type strain (541). Stand Genomic Sci (2009) 3.30
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J Biol Chem (2005) 3.19
The endless tale of non-homologous end-joining. Cell Res (2008) 3.03
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biol Chem (2005) 3.02
Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks. J Cell Biol (2007) 2.92
Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair (Amst) (2006) 2.67
Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. J Biol Chem (2006) 2.66
Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J Cell Biol (2005) 2.64
A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. Science (2006) 2.58
Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome. Blood (2002) 2.50
Two essential but distinct functions of the mammalian abasic endonuclease. Proc Natl Acad Sci U S A (2005) 2.26
Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance. Neoplasia (2010) 2.21
Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. Structure (2008) 2.17
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol Cell (2011) 2.16
Role of DNA-PK in the cellular response to DNA double-strand breaks. DNA Repair (Amst) (2004) 2.13
Decoding the fine-scale structure of a breast cancer genome and transcriptome. Genome Res (2006) 2.09
Differential effects of equiaxial and uniaxial strain on mesenchymal stem cells. Biotechnol Bioeng (2004) 2.05
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol Cell Biol (2010) 2.03
Ku recruits XLF to DNA double-strand breaks. EMBO Rep (2007) 2.00
Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability. Genes Dev (2005) 1.97
Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor beta1 stimulation. J Biol Chem (2004) 1.96
Complete genome sequence of Meiothermus ruber type strain (21). Stand Genomic Sci (2010) 1.96
DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc Natl Acad Sci U S A (2002) 1.92
Decontamination of MDA reagents for single cell whole genome amplification. PLoS One (2011) 1.91
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J Biol Chem (2009) 1.91
ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage. Sci Signal (2010) 1.86
PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors. Cancer Res (2010) 1.84
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining. J Clin Invest (2008) 1.82
Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer. Blood (2007) 1.82
Complete genome sequence of Pedobacter heparinus type strain (HIM 762-3). Stand Genomic Sci (2009) 1.82
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma. Cancer Res (2009) 1.79
A human breast cell model of preinvasive to invasive transition. Cancer Res (2008) 1.79
Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions. Structure (2004) 1.78
DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells. DNA Repair (Amst) (2006) 1.75
Suppression of nonhomologous end joining repair by overexpression of HMGA2. Cancer Res (2009) 1.73
Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences. Proc Natl Acad Sci U S A (2005) 1.68
Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res (2007) 1.68
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks. Nucleic Acids Res (2009) 1.66
Unrepaired clustered DNA lesions induce chromosome breakage in human cells. Proc Natl Acad Sci U S A (2011) 1.64
Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks. Cell Cycle (2011) 1.63
The DNA sequence and comparative analysis of human chromosome 5. Nature (2004) 1.62
DNA double strand break repair via non-homologous end-joining. Transl Cancer Res (2013) 1.61
Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro. J Biol Chem (2002) 1.60
DNA-PKcs function regulated specifically by protein phosphatase 5. Proc Natl Acad Sci U S A (2004) 1.60
Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair. Genes Dev (2011) 1.60
Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells. Proc Natl Acad Sci U S A (2011) 1.58
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat Struct Mol Biol (2006) 1.55
Exploring the symbiotic pangenome of the nitrogen-fixing bacterium Sinorhizobium meliloti. BMC Genomics (2011) 1.55
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. J Cell Biol (2009) 1.55
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection. Nature (2012) 1.53
DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys? J Cell Biol (2007) 1.48
Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response. Cell Cycle (2010) 1.48
Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells. EMBO Rep (2009) 1.46
A sequence-based survey of the complex structural organization of tumor genomes. Genome Biol (2008) 1.45
Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity. Int J Radiat Biol (2013) 1.42
Room-temperature single-nucleotide polymorphism and multiallele DNA detection using fluorescent nanocrystals and microarrays. Anal Chem (2003) 1.40
Defining interactions between DNA-PK and ligase IV/XRCC4. DNA Repair (Amst) (2002) 1.40
Fifty microdeletions among 112 cases of Sotos syndrome: low copy repeats possibly mediate the common deletion. Hum Mutat (2003) 1.38
Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions. DNA Repair (Amst) (2012) 1.37
Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts. Radiat Res (2008) 1.37
Retracted DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance. Cell (2009) 1.37
Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair. J Cell Biol (2011) 1.36
Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation. Nucleic Acids Res (2009) 1.34
A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins. BMC Genomics (2004) 1.34
Complete genome sequence of Eggerthella lenta type strain (IPP VPI 0255). Stand Genomic Sci (2009) 1.34
Phosphoproteome profiling of human skin fibroblast cells in response to low- and high-dose irradiation. J Proteome Res (2006) 1.33
MDC1 regulates DNA-PK autophosphorylation in response to DNA damage. J Biol Chem (2004) 1.32
Complete genome sequence of Spirosoma linguale type strain (1). Stand Genomic Sci (2010) 1.32
Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice. Genes Chromosomes Cancer (2003) 1.31
DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks. DNA Repair (Amst) (2008) 1.29
Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs. Mamm Genome (2004) 1.28
The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses. Neoplasia (2012) 1.28
Human Rad51C deficiency destabilizes XRCC3, impairs recombination, and radiosensitizes S/G2-phase cells. J Biol Chem (2004) 1.27
DNA-PKcs and ATM co-regulate DNA double-strand break repair. DNA Repair (Amst) (2009) 1.27
The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair. PLoS Genet (2013) 1.27
Downregulation of human DAB2IP gene expression in prostate cancer cells results in resistance to ionizing radiation. Cancer Res (2010) 1.26
Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression. DNA Repair (Amst) (2005) 1.25
DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53. EMBO J (2002) 1.21
Complete genome sequence of Chitinophaga pinensis type strain (UQM 2034). Stand Genomic Sci (2010) 1.21
Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation. Mutat Res (2010) 1.20
Engineered bacterial outer membrane vesicles with enhanced functionality. J Mol Biol (2008) 1.20
Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells. J Biol Chem (2005) 1.19