Published in Chemistry on August 19, 2005
Phosphorescent organic light-emitting devices: working principle and iridium based emitter materials. Int J Mol Sci (2008) 1.00
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med (2006) 13.54
Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts. Breast Cancer Res (2005) 8.73
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science (2008) 7.89
Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA (2011) 5.86
Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis. Cell (2005) 5.43
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer. JAMA (2011) 4.63
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature (2007) 4.35
IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol (2004) 3.84
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature (2005) 3.67
UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke. Cell (2006) 3.65
A real-time photoacoustic tomography system for small animals. Opt Express (2009) 2.97
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα. Cell (2013) 2.87
Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection. J Virol (2008) 2.84
High-detectivity polymer photodetectors with spectral response from 300 nm to 1450 nm. Science (2009) 2.78
Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription. Mol Cell (2007) 2.71
Structure and mechanism of human DNA polymerase eta. Nature (2010) 2.69
Ohio USA stoneflies (Insecta, Plecoptera): species richness estimation, distribution of functional niche traits, drainage affiliations, and relationships to other states. Zookeys (2012) 2.65
Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J Biol Chem (2010) 2.59
Random walk in orthogonal space to achieve efficient free-energy simulation of complex systems. Proc Natl Acad Sci U S A (2008) 2.56
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc Natl Acad Sci U S A (2007) 2.53
Periconceptional dietary intake of choline and betaine and neural tube defects in offspring. Am J Epidemiol (2004) 2.49
Urine neutrophil gelatinase-associated lipocalin levels do not improve risk prediction of progressive chronic kidney disease. Kidney Int (2013) 2.48
Inflammatory breast cancer: the disease, the biology, the treatment. CA Cancer J Clin (2010) 2.45
Estimating GFR among participants in the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis (2012) 2.42
Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41
Use of abdominopelvic computed tomography in emergency departments and rates of urgent diagnoses in Crohn's disease. Clin Gastroenterol Hepatol (2011) 2.40
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. EMBO J (2005) 2.37
Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other. Immunity (2003) 2.34
Gamma-secretase gene mutations in familial acne inversa. Science (2010) 2.30
Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study. Am J Kidney Dis (2011) 2.25
Simultaneous enhancement of open-circuit voltage, short-circuit current density, and fill factor in polymer solar cells. Adv Mater (2011) 2.25
Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. EMBO J (2006) 2.23
The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2. J Cell Biol (2004) 2.22
Delays in primary surgical treatment are not associated with significant tumor size progression in breast cancer patients. Ann Surg (2011) 2.16
Gene transfer to plants by diverse species of bacteria. Nature (2005) 2.11
Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts. Mol Cell (2004) 2.10
Association of serum bicarbonate with risk of renal and cardiovascular outcomes in CKD: a report from the Chronic Renal Insufficiency Cohort (CRIC) study. Am J Kidney Dis (2013) 2.09
Replication of a cis-syn thymine dimer at atomic resolution. Nature (2003) 2.07
Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res (2009) 2.07
Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-kappaB-dependent signaling pathway. J Immunol (2005) 2.03
Curved array photoacoustic tomographic system for small animal imaging. J Biomed Opt (2008) 2.01
Chimpanzee adenovirus antibodies in humans, sub-Saharan Africa. Emerg Infect Dis (2006) 1.99
Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2). Proc Natl Acad Sci U S A (2010) 1.96
Black soot and the survival of Tibetan glaciers. Proc Natl Acad Sci U S A (2009) 1.93
Multidisciplinary considerations in the implementation of the findings from the American College of Surgeons Oncology Group (ACOSOG) Z0011 study: a practice-changing trial. Ann Surg Oncol (2011) 1.93
Watching DNA polymerase η make a phosphodiester bond. Nature (2012) 1.92
Liposomal doxorubicin increases radiofrequency ablation-induced tumor destruction by increasing cellular oxidative and nitrative stress and accelerating apoptotic pathways. Radiology (2010) 1.84
Fibroblast growth factor-23 and cardiovascular events in CKD. J Am Soc Nephrol (2013) 1.78
Engaging hospitals to meet tuberculosis control targets in China: using the Internet as a tool to put policy into practice. Bull World Health Organ (2010) 1.76
Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review. Crit Care Med (2009) 1.75
Metabolic syndrome meets osteoarthritis. Nat Rev Rheumatol (2012) 1.75
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC Med Genet (2009) 1.74
Reduced risks of neural tube defects and orofacial clefts with higher diet quality. Arch Pediatr Adolesc Med (2011) 1.73
A multilevel adaptive finite element algorithm for bioluminescence tomography. Opt Express (2006) 1.71
Association of cardiac troponin T with left ventricular structure and function in CKD. Am J Kidney Dis (2013) 1.67
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Proc Natl Acad Sci U S A (2004) 1.66
Large liver tumors: protocol for radiofrequency ablation and its clinical application in 110 patients--mathematic model, overlapping mode, and electrode placement process. Radiology (2004) 1.65
Adherence to a healthy lifestyle and all-cause mortality in CKD. Clin J Am Soc Nephrol (2013) 1.64
Predicting the extent of nodal disease in early-stage breast cancer. Ann Surg Oncol (2014) 1.63
Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair. EMBO J (2004) 1.61
High-affinity peptide against MT1-MMP for in vivo tumor imaging. J Control Release (2011) 1.59
Crystal structure of T4 endonuclease VII resolving a Holliday junction. Nature (2007) 1.59
H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem (2007) 1.56
Orofacial clefts in the National Birth Defects Prevention Study, 1997-2004. Am J Med Genet A (2009) 1.55
In vitro and in vivo studies of MutS, MutL and MutH mutants: correlation of mismatch repair and DNA recombination. DNA Repair (Amst) (2003) 1.55
A structure-based model for the synthesis and hydrolysis of ATP by F1-ATPase. Cell (2005) 1.55
Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Cancer (2006) 1.54
PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol (2003) 1.54
Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defects. J Pediatr (2008) 1.52
An enzymatic atavist revealed in dual pathways for water activation. PLoS Biol (2008) 1.52
High-performance, all-solution-processed organic nanowire transistor arrays with inkjet-printing patterned electrodes. Langmuir (2011) 1.52
The draft genome of a socially polymorphic halictid bee, Lasioglossum albipes. Genome Biol (2013) 1.52
Bcl11a is essential for lymphoid development and negatively regulates p53. J Exp Med (2012) 1.51
Improving protein order-disorder classification using charge-hydropathy plots. BMC Bioinformatics (2014) 1.50
History-adjusted marginal structural analysis of the association between hemoglobin variability and mortality among chronic hemodialysis patients. Clin J Am Soc Nephrol (2008) 1.49
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. J Biol Chem (2004) 1.48
Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-kappaB paradigm. J Immunol (2009) 1.47
Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells. Stem Cells (2005) 1.46
A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients. Virology (2008) 1.45
Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A (2012) 1.44
Identification of candidate predictive and surrogate molecular markers for dasatinib in prostate cancer: rationale for patient selection and efficacy monitoring. Genome Biol (2007) 1.43
Catalytic mechanism of RNA backbone cleavage by ribonuclease H from quantum mechanics/molecular mechanics simulations. J Am Chem Soc (2011) 1.42
Development of new cancers in patients with DCIS: the M.D. Anderson experience. Ann Surg Oncol (2007) 1.42
Brain hyperthermia after traumatic brain injury does not reduce brain oxygen. Neurosurgery (2008) 1.42
Colorectal cancers with microsatellite instability display mRNA expression signatures characteristic of increased immunogenicity. Mol Cancer (2004) 1.42
Inflammatory breast cancer: what we know and what we need to learn. Oncologist (2012) 1.41
Air pollution and birth weight in northern Nevada, 1991-1999. Inhal Toxicol (2002) 1.41
Optimal probing of optical contrast of breast lesions of different size located at different depths by US localization. Technol Cancer Res Treat (2006) 1.40
Systematic identification of microRNA and messenger RNA profiles in hepatitis C virus-infected human hepatoma cells. Virology (2009) 1.40
Structural insight into translesion synthesis by DNA Pol II. Cell (2009) 1.39
Mutations in PRRT2 result in paroxysmal dyskinesias with marked variability in clinical expression. J Med Genet (2011) 1.38
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. J Biol Chem (2004) 1.37
PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming. Stem Cells (2011) 1.37
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis. J Clin Invest (2008) 1.36
Synergistic approach to improve "alchemical" free energy calculation in rugged energy surface. J Chem Phys (2007) 1.35
Product-assisted catalysis in base-excision DNA repair. Nat Struct Biol (2003) 1.34
SUMO2/3 conjugation is an endogenous neuroprotective mechanism. J Cereb Blood Flow Metab (2011) 1.32
A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer. Cancer Chemother Pharmacol (2010) 1.32
Simultaneous escaping of explicit and hidden free energy barriers: application of the orthogonal space random walk strategy in generalized ensemble based conformational sampling. J Chem Phys (2009) 1.31