Weight gain, schizophrenia and antipsychotics: new findings from animal model and pharmacogenomic studies.

PubWeight™: 0.79‹?›

🔗 View Article (PMC 3440684)

Published in Schizophr Res Treatment on December 06, 2010

Authors

Fabio Panariello1, Vincenzo De Luca, Andrea de Bartolomeis

Author Affiliations

1: Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Room 30, Toronto, ON, Canada M5T 1R8.

Articles cited by this

(truncated to the top 100)

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 12.66

Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet (2008) 10.20

Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci (1998) 9.88

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A (1998) 9.32

Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Expert Panel on the Identification, Evaluation, and Treatment of Overweight in Adults. Am J Clin Nutr (1998) 8.97

Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry (1999) 8.04

Brain dopamine and obesity. Lancet (2001) 8.00

Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature (2001) 6.36

Schizophrenia. Lancet (2004) 4.70

betaAR signaling required for diet-induced thermogenesis and obesity resistance. Science (2002) 4.47

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors. Nature (1995) 4.36

Excess mortality of schizophrenia. A meta-analysis. Br J Psychiatry (1997) 4.07

Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry (2005) 3.74

Pharmacogenetic prediction of clozapine response. Lancet (2000) 3.10

To eat or to sleep? Orexin in the regulation of feeding and wakefulness. Annu Rev Neurosci (2001) 2.84

Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet (2002) 2.77

Specificity in the projection patterns of accumbal core and shell in the rat. Neuroscience (1991) 2.58

Mortality and medical comorbidity among psychiatric patients: a review. Psychiatr Serv (1996) 2.52

Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake. Endocrinology (2002) 2.51

Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc Natl Acad Sci U S A (1999) 2.39

Neuroendocrine control of food intake. Nutr Metab Cardiovasc Dis (2007) 2.21

Antipsychotic metabolic effects: weight gain, diabetes mellitus, and lipid abnormalities. Can J Psychiatry (2001) 2.11

Metabolic considerations in the use of antipsychotic medications: a review of recent evidence. J Clin Psychiatry (2007) 2.03

Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics (2005) 1.97

Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles. Mol Psychiatry (2007) 1.93

Insulin, leptin, and food reward: update 2008. Am J Physiol Regul Integr Comp Physiol (2008) 1.84

RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist. Neuropharmacology (1997) 1.83

Psychosis pathways converge via D2high dopamine receptors. Synapse (2006) 1.78

Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol. Br J Psychiatry (2005) 1.68

Role of neuropeptides in appetite regulation and obesity--a review. Neuropeptides (2006) 1.67

Meta-analysis of linkage data under worst-case conditions: a demonstration using the human OB region. Genetics (1998) 1.64

Hypothalamic dopamine and serotonin in the regulation of food intake. Nutrition (2000) 1.63

Cocaine-induced suppression of saccharin intake: a model of drug-induced devaluation of natural rewards. Behav Neurosci (2002) 1.62

Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry (2001) 1.58

Body fat and the activity of the autonomic nervous system. N Engl J Med (1988) 1.58

Acutely reduced locomotor activity is a major contributor to Western diet-induced obesity in mice. Am J Physiol Endocrinol Metab (2007) 1.58

Peripheral injection of risperidone, an atypical antipsychotic, alters the bodyweight gain of rats. Clin Exp Pharmacol Physiol (2002) 1.56

Feeding behavior in dopamine-deficient mice. Proc Natl Acad Sci U S A (1999) 1.56

Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research. Mol Psychiatry (2007) 1.55

Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia. CNS Drugs (2006) 1.54

Abnormalities in glucose metabolism in patients with schizophrenia treated with atypical antipsychotic medications. Am J Med (2008) 1.53

Risk of treatment-emergent diabetes mellitus in patients receiving antipsychotics. Ann Pharmacother (2007) 1.49

Altered basal and stimulated accumbens dopamine release in obese OLETF rats as a function of age and diabetic status. Am J Physiol Regul Integr Comp Physiol (2007) 1.49

Cannabinoid CB1 receptors control conditioned drug seeking. Trends Pharmacol Sci (2005) 1.45

Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS. Neuropharmacology (2000) 1.43

A neural systems analysis of the potentiation of feeding by conditioned stimuli. Physiol Behav (2005) 1.43

Mesolimbic dopaminergic system activity as a function of food reward: a microdialysis study. Pharmacol Biochem Behav (1996) 1.33

Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecystokinin. Physiol Behav (2006) 1.33

Expression of dopaminergic receptors in the hypothalamus of lean and obese Zucker rats and food intake. Am J Physiol Regul Integr Comp Physiol (2002) 1.33

Receptor occupancy-based analysis of the contributions of various receptors to antipsychotics-induced weight gain and diabetes mellitus. Drug Metab Pharmacokinet (2005) 1.32

The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin. J Endocrinol (1999) 1.28

Diabetes mellitus in schizophrenic patients. Compr Psychiatry (1996) 1.27

Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology (2005) 1.26

Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. Diabetes (2004) 1.25

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction. Schizophr Res (2006) 1.25

The role of gastrointestinal vagal afferents in the control of food intake: current prospects. Nutrition (2000) 1.23

Metabolic syndrome and mental illness. Am J Manag Care (2007) 1.23

Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects. Pharmacol Rev (2001) 1.22

The pharmacology of the endocannabinoid system: functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction. Addict Biol (2008) 1.21

Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine. Am J Psychiatry (2002) 1.21

Differential activation of orexin neurons by antipsychotic drugs associated with weight gain. J Neurosci (2002) 1.20

Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies. Psychopharmacology (Berl) (2006) 1.17

The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding. J Neurosci Res (2000) 1.16

What psychological process mediates feeding evoked by electrical stimulation of the lateral hypothalamus? Behav Neurosci (1991) 1.13

Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist and d-fenfluramine on feeding patterns in the rat. Psychopharmacology (Berl) (2000) 1.13

Investigation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat. Br J Pharmacol (1997) 1.13

Antipsychotic drug action: antagonism, inverse agonism or partial agonism. Trends Pharmacol Sci (2008) 1.12

Insulin binds to brain blood vessels in vivo. Nature (1979) 1.10

The evaluation of insulin as a metabolic signal influencing behavior via the brain. Neurosci Biobehav Rev (1996) 1.09

Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations. Metabolism (2007) 1.08

Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes (2005) 1.08

Meta-analysis of the association of Trp64Arg polymorphism of beta 3-adrenergic receptor gene with body mass index. J Clin Endocrinol Metab (1998) 1.08

Elevated hemoglobin A1c as a possible indicator of diabetes mellitus and diabetic ketoacidosis in schizophrenia patients receiving atypical antipsychotics. J Clin Psychiatry (2007) 1.07

The CATIE schizophrenia trial: results, impact, controversy. Harv Rev Psychiatry (2007) 1.05

A parametric analysis of olanzapine-induced weight gain in female rats. Psychopharmacology (Berl) (2005) 1.04

Localization of the 5-hydroxytryptamine2C receptor protein in human and rat brain using specific antisera. Neuropharmacology (1995) 1.04

Clozapine-induced weight gain predicts improvement in psychopathology. Schizophr Res (2003) 1.04

Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus. Neuropharmacology (2005) 1.03

Association of the HTR2C gene and antipsychotic induced weight gain: a meta-analysis. Int J Neuropsychopharmacol (2007) 1.02

Adrenoceptor genes in human obesity. J Intern Med (1999) 1.02

Adiposity signals, genetic and body weight regulation in humans. Diabetes Metab (2004) 1.02

Targeted disruption of histamine H1-receptor attenuates regulatory effects of leptin on feeding, adiposity, and UCP family in mice. Diabetes (2001) 1.01

Receptor mechanisms in the treatment of schizophrenia. J Psychopharmacol (2004) 1.00

Chronic treatment with antipsychotics in rats as a model for antipsychotic-induced weight gain in human. Pharmacol Biochem Behav (2003) 1.00

Relationships between the taqI polymorphism of the dopamine D2 receptor and blood pressure in hyperglycaemic and normoglycaemic Chinese subjects. Clin Endocrinol (Oxf) (2001) 1.00

Neuropharmacology of second-generation antipsychotic drugs: a validity of the serotonin-dopamine hypothesis. Prog Brain Res (2008) 0.98

Identification of polymorphic loci in the promoter region of the serotonin 5-HT2C receptor gene and their association with obesity and type II diabetes. Diabetologia (2000) 0.98

Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways. J Mol Neurosci (2005) 0.97

An animal model of antipsychotic-induced weight gain. Behav Brain Res (2004) 0.97

The role of thermogenesis in antipsychotic drug-induced weight gain. Obesity (Silver Spring) (2008) 0.97

A review of the effect of atypical antipsychotics on weight. Psychoneuroendocrinology (2003) 0.96

Adipokines that link obesity and diabetes to the hypothalamus. Prog Brain Res (2006) 0.96

Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. J Clin Psychiatry (2008) 0.96

Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study. J Pharmacol Exp Ther (1989) 0.96

Genetic dissection of atypical antipsychotic-induced weight gain: novel preliminary data on the pharmacogenetic puzzle. J Clin Psychiatry (2001) 0.96

Involvement of dopamine and opioids in the motivation to eat: influence of palatability, homeostatic state, and behavioral paradigms. Psychopharmacology (Berl) (2008) 0.96

The metabolic and cardiovascular effects of hyperthyroidism are largely independent of beta-adrenergic stimulation. Endocrinology (2004) 0.95

Genomics and the future of pharmacotherapy in psychiatry. Int Rev Psychiatry (2007) 0.95

Dopamine and serotonin interactions in the prefrontal cortex: insights on antipsychotic drugs and their mechanism of action. Pharmacopsychiatry (2007) 0.95

Weight gain in patients with schizophrenia treated with risperidone, olanzapine, quetiapine or haloperidol: results of the EIRE study. Schizophr Res (2003) 0.93

Articles by these authors

The Arabidopsis NPR1 protein is a receptor for the plant defense hormone salicylic acid. Cell Rep (2012) 2.13

Role of ethnicity in antipsychotic-induced weight gain and tardive dyskinesia: genes or environment? Pharmacogenomics (2013) 1.97

The leaf epidermome of Catharanthus roseus reveals its biochemical specialization. Plant Cell (2008) 1.60

Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants. Plant J (2008) 1.55

Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest. J Biotechnol (2013) 1.32

Translocator protein (18 kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA. J Cereb Blood Flow Metab (2012) 1.22

Synthetic biosystems for the production of high-value plant metabolites. Trends Biotechnol (2011) 1.19

N-methyl-D-aspartate receptor NR2B subunit gene GRIN2B in schizophrenia and bipolar disorder: Polymorphisms and mRNA levels. Schizophr Res (2006) 1.18

Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle. Proc Natl Acad Sci U S A (2010) 1.17

Mesocarp localization of a bi-functional resveratrol/hydroxycinnamic acid glucosyltransferase of Concord grape (Vitis labrusca). Plant J (2007) 1.15

Application of carborundum abrasion for investigating the leaf epidermis: molecular cloning of Catharanthus roseus 16-hydroxytabersonine-16-O-methyltransferase. Plant J (2007) 1.12

Serotonin transporter polymorphisms and persistent, pervasive childhood aggression. Am J Psychiatry (2006) 1.08

Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus. Plant J (2005) 1.08

Expressed sequence tags from Madagascar periwinkle (Catharanthus roseus). FEBS Lett (2006) 1.05

Bio-fermentation of modified flavonoids: an example of in vivo diversification of secondary metabolites. Phytochemistry (2004) 1.04

A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle. Plant Cell (2013) 1.03

Association of the HTR2C gene and antipsychotic induced weight gain: a meta-analysis. Int J Neuropsychopharmacol (2007) 1.02

The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia. Neurosci Lett (2005) 1.02

Identification of a low vindoline accumulating cultivar of Catharanthus roseus (L.) G. Don by alkaloid and enzymatic profiling. Phytochemistry (2006) 0.99

Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations. Psychopharmacology (Berl) (2005) 0.97

ATP-binding cassette transporter controls leaf surface secretion of anticancer drug components in Catharanthus roseus. Proc Natl Acad Sci U S A (2013) 0.95

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1. BMC Med Genet (2014) 0.95

Virus-induced gene silencing identifies Catharanthus roseus 7-deoxyloganic acid-7-hydroxylase, a step in iridoid and monoterpene indole alkaloid biosynthesis. Plant J (2013) 0.94

Cloning and regiospecificity studies of two flavonoid glucosyltransferases from Allium cepa. Phytochemistry (2003) 0.93

Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions. J Cereb Blood Flow Metab (2006) 0.92

Targeting the Noradrenergic System in Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis of Prazosin Trials. Curr Drug Targets (2015) 0.89

Association of alpha4beta2 nicotinic receptor and heavy smoking in schizophrenia. J Psychiatry Neurosci (2007) 0.88

A pair of tabersonine 16-hydroxylases initiates the synthesis of vindoline in an organ-dependent manner in Catharanthus roseus. Plant Physiol (2013) 0.88

Association study of tardive dyskinesia and twelve DRD2 polymorphisms in schizophrenia patients. Int J Neuropsychopharmacol (2006) 0.88

Utilization of the genetic resources of wild species to create a nontransgenic high flavonoid tomato. J Agric Food Chem (2005) 0.88

Age-related differences in distractor interference on line bisection. Exp Brain Res (2014) 0.87

Decreased levels of D-aspartate and NMDA in the prefrontal cortex and striatum of patients with schizophrenia. J Psychiatr Res (2013) 0.87

No association between the Pro197Leu polymorphism in the glutathione peroxidase (GPX1) gene and schizophrenia. Psychiatr Genet (2004) 0.87

Mixture regression analysis on age at onset in bipolar disorder patients: investigation of the role of serotonergic genes. Eur Neuropsychopharmacol (2010) 0.87

Association of antipsychotic induced weight gain and body mass index with GNB3 gene: a meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.87

Expression of deacetylvindoline-4-O-acetyltransferase in Catharanthus roseus hairy roots. Phytochemistry (2007) 0.86

Suggestive association between the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) and clinical improvement with antipsychotics in schizophrenia. Eur Neuropsychopharmacol (2005) 0.86

Correlation of a set of gene variants, life events and personality features on adult ADHD severity. J Psychiatr Res (2009) 0.86

The brain-derived neurotrophic factor gene in suicidal behaviour: a meta-analysis. Int J Neuropsychopharmacol (2011) 0.86

Wound-inducible biosynthesis of phytoalexin hydroxycinnamic acid amides of tyramine in tryptophan and tyrosine decarboxylase transgenic tobacco lines. Plant Physiol (2005) 0.85

Dysbindin C-A-T haplotype is associated with thicker medial orbitofrontal cortex in healthy population. Neuroimage (2010) 0.85

The biosynthesis and regulation of biosynthesis of Concord grape fruit esters, including 'foxy' methylanthranilate. Plant J (2005) 0.85

Vindoline biosynthesis is transcriptionally blocked in Catharanthus roseus cell suspension cultures. Mol Biotechnol (2002) 0.84

Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response. J Psychopharmacol (2006) 0.84

Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia: further evidence for a role in schizophrenia. Neuromolecular Med (2007) 0.84

Selective regulation of presynaptic calcium/calmodulin-dependent protein kinase II by psychotropic drugs. Biol Psychiatry (2003) 0.84

Clozapine impairs insulin action by up-regulating Akt phosphorylation and Ped/Pea-15 protein abundance. J Cell Physiol (2012) 0.83

Genetic association analysis of the glutathione peroxidase (GPX1) gene polymorphism (Pro197Leu) with tardive dyskinesia. Psychiatry Res (2006) 0.83

759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain. Lancet (2002) 0.83

Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric diseases. Neurochem Res (2012) 0.83

The acute and chronic effects of combined antipsychotic-mood stabilizing treatment on the expression of cortical and striatal postsynaptic density genes. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.82

Jasmonate-induced epoxidation of tabersonine by a cytochrome P-450 in hairy root cultures of Catharanthus roseus. Phytochemistry (2003) 0.82

Gene-gene interaction between MAOA and COMT in suicidal behavior: analysis in schizophrenia. Brain Res (2006) 0.82

Exercise increases the level of plasma orexin A in humans. J Basic Clin Physiol Pharmacol (2016) 0.81

Genetic association between the dopamine D3 gene polymorphism (Ser9Gly) and schizophrenia in Japanese populations: evidence from a case-control study and meta-analysis. Neurosci Lett (2008) 0.81

Dopamine receptor subtypes contribution to Homer1a induction: insights into antipsychotic molecular action. Prog Neuropsychopharmacol Biol Psychiatry (2009) 0.81

Serotonin transporter gene and adverse life events in adult ADHD. Am J Med Genet B Neuropsychiatr Genet (2008) 0.81

Ethnicity and age at onset in bipolar spectrum disorders. CNS Spectr (2011) 0.81

Analysis of treatment-resistant schizophrenia and 384 markers from candidate genes. Pharmacogenet Genomics (2012) 0.81

Antidepressants activate CaMKII in neuron cell body by Thr286 phosphorylation. Neuroreport (2004) 0.81

Divergent acute and chronic modulation of glutamatergic postsynaptic density genes expression by the antipsychotics haloperidol and sertindole. Psychopharmacology (Berl) (2010) 0.81

Peripheral glutamate levels in schizophrenia: evidence from a meta-analysis. Neuropsychobiology (2014) 0.80

Association study between the novel functional polymorphism of the serotonin transporter gene and suicidal behaviour in schizophrenia. Eur Neuropsychopharmacol (2005) 0.80

Finite mixture regression model analysis on antipsychotics induced weight gain: investigation of the role of the serotonergic genes. Eur Neuropsychopharmacol (2012) 0.80

Serotonin system genes and childhood-onset aggression. Psychiatr Genet (2007) 0.80

Age at onset in Canadian schizophrenia patients: admixture analysis. Schizophr Res (2009) 0.80

Association of the alpha 2A adrenergic receptor -1291C/G polymorphism and antipsychotic-induced weight gain in European-Americans. Pharmacogenomics (2009) 0.79

Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores. World J Biol Psychiatry (2010) 0.79

Dandy-Walker syndrome with psychotic symptoms: a case report. Riv Psichiatr (2014) 0.79

Lack of association between the corticotrophin-releasing hormone receptor 2 gene and panic disorder. Psychiatr Genet (2006) 0.79

Admixture analysis of age at onset in major depressive disorder. Gen Hosp Psychiatry (2012) 0.79

Functional characterization of amyrin synthase involved in ursolic acid biosynthesis in Catharanthus roseus leaf epidermis. Phytochemistry (2012) 0.79

Investigation of the dopamine D5 receptor gene (DRD5) in adult attention deficit hyperactivity disorder. Neurosci Lett (2007) 0.79

Admixture analysis of age at onset in schizophrenia: evidence of three subgroups in a first-episode sample. Gen Hosp Psychiatry (2013) 0.78

The role of ethnicity in treatment refractory schizophrenia. Compr Psychiatry (2012) 0.78

Antipsychotic and antidepressant co-treatment: effects on transcripts of inducible postsynaptic density genes possibly implicated in behavioural disorders. Brain Res Bull (2009) 0.78

Molecular cloning and biochemical characterization of three Concord grape (Vitis labrusca) flavonol 7-O-glucosyltransferases. Planta (2011) 0.78

Method for quantitative in situ hybridization histochemistry and image analysis applied for Homer1a gene expression in rat brain. Brain Res Brain Res Protoc (2003) 0.78

Pattern of acute induction of Homer1a gene is preserved after chronic treatment with first- and second-generation antipsychotics: effect of short-term drug discontinuation and comparison with Homer1a-interacting genes. J Psychopharmacol (2010) 0.78

Genetic study of BDNF, DRD3, and their interaction in tardive dyskinesia. Eur Neuropsychopharmacol (2009) 0.78

The role of leptin in antipsychotic-induced weight gain: genetic and non-genetic factors. J Obes (2012) 0.78

Homer 1a gene expression modulation by antipsychotic drugs: involvement of the glutamate metabotropic system and effects of D-cycloserine. Neuropsychopharmacology (2002) 0.78

Tobacco smoking in treatment-resistant schizophrenia patients is associated with impaired cognitive functioning, more severe negative symptoms, and poorer social adjustment. Neuropsychiatr Dis Treat (2013) 0.77

HOMER1 promoter analysis in Parkinson's disease: association study with psychotic symptoms. Neuropsychobiology (2009) 0.77

Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case-control and family based study designs. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.77

Genetic association between the dopamine D3 receptor gene polymorphism (Ser9Gly) and tardive dyskinesia in patients with schizophrenia: a reevaluation in East Asian populations. Neurosci Lett (2011) 0.77

Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia. Neuromolecular Med (2008) 0.77

Meta-analysis of P300 waveform in panic disorder. Exp Brain Res (2014) 0.77

The role of intranasal oxytocin in the treatment of patients with schizophrenia: a systematic review. CNS Neurol Disord Drug Targets (2013) 0.77

Neuregulin 1 and age of onset in the major psychoses. J Neural Transm (Vienna) (2009) 0.77

Association study of the gamma-aminobutyric acid type a receptor gamma2 subunit gene with schizophrenia. Schizophr Res (2009) 0.77

Haloperidol induces higher Homer1a expression than risperidone, olanzapine and sulpiride in striatal sub-regions. Psychiatry Res (2010) 0.77

Haplotype association study between DRD1 gene and bipolar type I affective disorder in two samples from Canada and Sardinia. Am J Med Genet B Neuropsychiatr Genet (2007) 0.76

Lack of association between dopamine-β hydroxylase gene and a history of suicide attempt in schizophrenia: comparison of molecular and statistical haplotype analyses. Psychiatr Genet (2014) 0.76

The catechol-O-methyl-transferase gene in tardive dyskinesia. World J Biol Psychiatry (2010) 0.76

Molecular cloning and biochemical characterization of the UDP-glucose: flavonoid 3-O-glucosyltransferase from Concord grape (Vitis labrusca). Phytochemistry (2011) 0.76

MDR1 gene in tardive dyskinesia scale scores: comparison of strategies for quantitative trait haplotype analysis. Schizophr Res (2009) 0.76

Hormonal changes in menopause and orexin-a action. Obstet Gynecol Int (2013) 0.76

Ethnicity and suicide attempt: analysis in bipolar disorder and schizophrenia. BMC Psychiatry (2013) 0.76