Published in Int J Biochem Cell Biol on September 01, 2005
Tumor self-seeding by circulating cancer cells. Cell (2009) 6.66
Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases. Clin Cancer Res (2008) 3.67
Role of fascin in filopodial protrusion. J Cell Biol (2006) 3.52
Migrastatin analogues target fascin to block tumour metastasis. Nature (2010) 2.84
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J Cell Biol (2010) 2.62
miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer (2010) 2.51
mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proc Natl Acad Sci U S A (2008) 2.48
The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr Biol (2010) 2.23
Ena/VASP proteins have an anti-capping independent function in filopodia formation. Mol Biol Cell (2007) 2.12
Proinvasion metastasis drivers in early-stage melanoma are oncogenes. Cancer Cell (2011) 1.99
Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas. BMC Cancer (2006) 1.62
Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis. Mol Biol Cell (2007) 1.45
Fascin Regulates Nuclear Movement and Deformation in Migrating Cells. Dev Cell (2016) 1.45
The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1. PLoS One (2012) 1.22
Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog. J Am Chem Soc (2010) 1.19
Mechanism of actin filament bundling by fascin. J Biol Chem (2011) 1.18
Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis. BMC Med (2013) 1.09
Involvement of CYR61 and CTGF in the fascin-mediated proliferation and invasiveness of esophageal squamous cell carcinomas cells. Am J Pathol (2010) 1.08
Comparative proteome analysis of human epithelial ovarian cancer. Proteome Sci (2007) 1.08
Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis. Cancer Res (2010) 1.07
Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma. Br J Cancer (2007) 1.04
Fascin promotes filopodia formation independent of its role in actin bundling. J Cell Biol (2012) 1.04
Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: a regional study. J Cell Mol Med (2007) 1.02
Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells. PLoS One (2009) 1.01
Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells. J Biol Chem (2011) 1.00
MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1. Br J Cancer (2014) 1.00
Molecular mechanism of fascin function in filopodial formation. J Biol Chem (2012) 0.99
Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation. Development (2013) 0.96
Fascin1 promotes cell migration of mature dendritic cells. J Immunol (2011) 0.95
Fascin1 is dispensable for mouse development but is favorable for neonatal survival. Cell Motil Cytoskeleton (2009) 0.95
A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability. BMC Biol (2012) 0.94
Fascin-1, ezrin and paxillin contribute to the malignant progression and are predictors of clinical prognosis in laryngeal squamous cell carcinoma. PLoS One (2012) 0.93
GATA3 transcription factor abrogates Smad4 transcription factor-mediated fascin overexpression, invadopodium formation, and breast cancer cell invasion. J Biol Chem (2013) 0.91
Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma. BMC Cancer (2012) 0.90
RhoD activated by fibroblast growth factor induces cytoneme-like cellular protrusions through mDia3C. Mol Biol Cell (2012) 0.88
Idiopathic pulmonary fibrosis and cancer: do they really look similar? BMC Med (2015) 0.88
Association of EMMPRIN and fascin expression in renal cell carcinoma: correlation with clinicopathological parameters. World J Urol (2006) 0.86
Drosophila Fascin is a novel downstream target of prostaglandin signaling during actin remodeling. Mol Biol Cell (2012) 0.86
The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro. Br J Cancer (2009) 0.84
Fascin1 expression in high-grade serous ovarian carcinoma is a prognostic marker and knockdown of fascin1 suppresses the proliferation of ovarian cancer cells. Int J Oncol (2013) 0.84
Gefitinib-mediated reactive oxygen specie (ROS) instigates mitochondrial dysfunction and drug resistance in lung cancer cells. J Biol Chem (2015) 0.84
The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion. Cell Adh Migr (2014) 0.83
Sevoflurane inhibits invasion and migration of lung cancer cells by inactivating the p38 MAPK signaling pathway. J Anesth (2012) 0.82
Multiple interferon regulatory factor and NF-κB sites cooperate in mediating cell-type- and maturation-specific activation of the human CD83 promoter in dendritic cells. Mol Cell Biol (2013) 0.82
Signal transducer and activator of transcription 3 signaling upregulates fascin via nuclear factor-κB in gastric cancer: Implications in cell invasion and migration. Oncol Lett (2014) 0.81
Fascin promotes the motility and invasiveness of pancreatic cancer cells. World J Gastroenterol (2011) 0.81
Targeted inhibition of fascin function blocks tumour invasion and metastatic colonization. Nat Commun (2015) 0.81
Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture. Mol Biol Cell (2015) 0.81
MicroRNA-145 and MicroRNA-133a Inhibited Proliferation, Migration, and Invasion, While Promoted Apoptosis in Hepatocellular Carcinoma Cells Via Targeting FSCN1. Dig Dis Sci (2015) 0.80
Marker-free phenotyping of tumor cells by fractal analysis of reflection interference contrast microscopy images. Nano Lett (2013) 0.79
The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration. Cell Commun Signal (2014) 0.78
Fascin-1 is a novel biomarker of aggressiveness in some carcinomas. BMC Med (2013) 0.78
Fas Signaling Promotes Gastric Cancer Metastasis through STAT3-Dependent Upregulation of Fascin. PLoS One (2015) 0.78
Fascin over expression is associated with dysplastic changes in sinonasal inverted papillomas: a study of 47 cases. Head Neck Pathol (2009) 0.78
Association of Fascin and matrix metalloproteinase-9 expression with poor prognostic parameters in breast carcinoma of Egyptian women. Diagn Pathol (2014) 0.77
Fascin expression predicts an aggressive clinical course in patients with advanced breast cancer. Oncol Lett (2015) 0.77
Sevoflurane suppresses hypoxia-induced growth and metastasis of lung cancer cells via inhibiting hypoxia-inducible factor-1α. J Anesth (2015) 0.77
20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer. Oncotarget (2017) 0.77
A simplicial complex-based approach to unmixing tumor progression data. BMC Bioinformatics (2015) 0.76
Expression of extracellular matrix metalloproteinase inducer and fascin in urinary bladder cancer: Correlation with clinicopathological characteristics. Mol Clin Oncol (2013) 0.76
β-Catenin/CBP-Dependent Signaling Regulates TGF-β-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells. Invest Ophthalmol Vis Sci (2016) 0.76
NOX1 supports the metabolic remodeling of HepG2 cells. PLoS One (2015) 0.75
Fascin expression in pleomorphic adenoma and mucoepidermoid carcinoma. Dent Res J (Isfahan) (2014) 0.75
Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nat Commun (2016) 0.75
Fascin, may the Forked be with you. Fly (Austin) (2014) 0.75
Monoubiquitination Inhibits the Actin Bundling Activity of Fascin. J Biol Chem (2016) 0.75
A role for fascin in preventing filopodia breakage in Drosophila tracheal cells. Commun Integr Biol (2014) 0.75
Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. FASEB J (2002) 3.45
Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals. BMC Bioinformatics (2003) 2.10
Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms. Mod Pathol (2008) 1.95
Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro. Am J Pathol (2003) 1.80
The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course. Clin Cancer Res (2005) 1.68
Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas. BMC Cancer (2006) 1.62
Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats. EMBO J (2004) 1.62
Laparoscopic anatrophic nephrolithotomy: feasibility study in a chronic porcine model. J Urol (2003) 1.58
Poor interobserver agreement in the distinction of high-grade dysplasia and adenocarcinoma in pretreatment Barrett's esophagus biopsies. Am J Gastroenterol (2008) 1.46
Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis. Mol Biol Cell (2007) 1.45
Interaction of fascin and protein kinase Calpha: a novel intersection in cell adhesion and motility. EMBO J (2003) 1.45
BRAF mutations in colorectal cancer are associated with distinct clinical characteristics and worse prognosis. Dis Colon Rectum (2012) 1.42
The evolution of extracellular matrix. Mol Biol Cell (2010) 1.40
Prostate cancer in African American men is associated with downregulation of zinc transporters. Appl Immunohistochem Mol Morphol (2003) 1.37
Reflex UroVysion testing of bladder cancer surveillance patients with equivocal or negative urine cytology: a prospective study with focus on the natural history of anticipatory positive findings. Am J Clin Pathol (2007) 1.36
The roles of fascins in health and disease. J Pathol (2011) 1.35
Dual-color, break-apart fluorescence in situ hybridization for EWS gene rearrangement distinguishes clear cell sarcoma of soft tissue from malignant melanoma. Mod Pathol (2005) 1.19
Development of a clinically feasible molecular assay to predict recurrence of stage II colon cancer. J Mol Diagn (2008) 1.17
Novel role of the muskelin-RanBP9 complex as a nucleocytoplasmic mediator of cell morphology regulation. J Cell Biol (2008) 1.15
Expression of fascin-1, the gene encoding the actin-bundling protein fascin-1, during mouse embryogenesis. Gene Expr Patterns (2004) 1.14
The evolution of thrombospondins and their ligand-binding activities. Mol Biol Evol (2010) 1.12
Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis. BMC Med (2013) 1.09
Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates. BMC Genomics (2006) 1.07
The influence of polysomy 17 on HER2 gene and protein expression in adenocarcinoma of the breast: a fluorescent in situ hybridization, immunohistochemical, and isotopic mRNA in situ hybridization study. Am J Surg Pathol (2005) 1.05
Prediction and analysis of higher-order coiled-coils: insights from proteins of the extracellular matrix, tenascins and thrombospondins. Int J Biochem Cell Biol (2013) 1.03
Rac regulates the interaction of fascin with protein kinase C in cell migration. J Cell Sci (2008) 1.01
Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells. PLoS One (2009) 1.01
Trimeric assembly of the C-terminal region of thrombospondin-1 or thrombospondin-2 is necessary for cell spreading and fascin spike organisation. J Cell Sci (2002) 1.01
Eccrine angiomatous hamartoma in a neurofibromatosis type-1 patient. Pathology (2002) 1.01
Chromosomal gains and genomic loss of p53 and p16 genes in Barrett's esophagus detected by fluorescence in situ hybridization of cytology specimens. Mod Pathol (2004) 1.00
Transfer and multiplex immunoblotting of a paraffin embedded tissue. Proteomics (2006) 0.98
Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: an immunohistochemical study of clinically annotated tumors. BMC Cancer (2008) 0.98
Functional role of syndecan-1 cytoplasmic V region in lamellipodial spreading, actin bundling, and cell migration. Mol Biol Cell (2005) 0.97
Neuronal expression of muskelin in the rodent central nervous system. BMC Neurosci (2007) 0.96
Primary extraosseous ewing sarcoma of the kidney with level III inferior vena cava thrombus. Clin Genitourin Cancer (2009) 0.96
Identifying Lynch syndrome: we are all responsible. Dis Colon Rectum (2008) 0.95
Adhesion-modulating/matricellular ECM protein families: a structural, functional and evolutionary appraisal. Matrix Biol (2012) 0.95
Coronary artery disease and the thrombospondin single nucleotide polymorphisms. Int J Biochem Cell Biol (2004) 0.94
A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability. BMC Biol (2012) 0.94
Analytical validation and interobserver reproducibility of EnzMet GenePro: a second-generation bright-field metallography assay for concomitant detection of HER2 gene status and protein expression in invasive carcinoma of the breast. Am J Surg Pathol (2005) 0.93
Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor. Int J Biochem Cell Biol (2002) 0.92
Regulation of post-translational modifications of muskelin by protein kinase C. Int J Biochem Cell Biol (2006) 0.91
Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells. J Cell Sci (2002) 0.91
Statin therapy is associated with improved pathologic response to neoadjuvant chemoradiation in rectal cancer. Dis Colon Rectum (2013) 0.91
Molecular phylogeny of a RING E3 ubiquitin ligase, conserved in eukaryotic cells and dominated by homologous components, the muskelin/RanBPM/CTLH complex. PLoS One (2013) 0.91
Fluorescence in situ hybridization of cytologic specimens from Barrett's esophagus: a pilot feasibility study. Gastrointest Endosc (2004) 0.89
The utility of fluorescence in situ hybridization (FISH) in the diagnosis of myxoid soft tissue neoplasms. Am J Surg Pathol (2008) 0.88
Gold-facilitated in situ hybridization: a bright-field autometallographic alternative to fluorescence in situ hybridization for detection of Her-2/neu gene amplification. Am J Pathol (2002) 0.87
MAL is expressed in a subset of Hodgkin lymphoma and identifies a population of patients with poor prognosis. Am J Clin Pathol (2006) 0.87
Phylogenomic analysis of vertebrate thrombospondins reveals fish-specific paralogues, ancestral gene relationships and a tetrapod innovation. BMC Evol Biol (2006) 0.87
Effect of intentional cryo-injury to the renal collecting system. J Urol (2003) 0.87
Microarray gene expression profiling and analysis in renal cell carcinoma. BMC Urol (2004) 0.86
Molecular analysis of muskelin identifies a conserved discoidin-like domain that contributes to protein self-association. Biochem J (2004) 0.86
The specificity of interphase FISH translocation probes in formalin fixed paraffin embedded tissue sections is readily assessed using automated staining and scoring of tissue microarrays constructed from murine xenografts. J Mol Histol (2006) 0.86
Epithelioid sarcoma: an immunohistochemical analysis evaluating the utility of cytokeratin 5/6 in distinguishing superficial epithelioid sarcoma from spindled squamous cell carcinoma. J Cutan Pathol (2003) 0.86
Novel bright field molecular morphology methods for detection of HER2 gene amplification. J Mol Histol (2004) 0.84
Primary intravascular synovial sarcoma: a disease of young adult women? Report of a case diagnosed by aspiration biopsy and review of the literature. Diagn Cytopathol (2006) 0.82
Prediction of adenocarcinoma in esophagectomy specimens based upon analysis of preresection biopsies of Barrett esophagus with at least high-grade dysplasia: a comparison of 2 systems. Am J Surg Pathol (2012) 0.81
Familial colorectal cancer type X: polyp burden and cancer risk stratification via a family history score. ANZ J Surg (2012) 0.80
The utility of FOXO1 fluorescence in situ hybridization (FISH) in formalin-fixed paraffin-embedded specimens in the diagnosis of alveolar rhabdomyosarcoma. Diagn Mol Pathol (2009) 0.79
Interobserver interpretative reproducibility of GOLDFISH, a first generation gold-facilitated autometallographic bright field in situ hybridization assay for HER-2/neu amplification in invasive mammary carcinoma. Am J Surg Pathol (2002) 0.79
Array-based comparative genomic hybridization in ulcerative colitis neoplasia: single non-dysplastic biopsies distinguish progressors from non-progressors. Mod Pathol (2010) 0.78
Laparoscopic ureterocalicostomy: a feasibility study. J Urol (2003) 0.78
A thrombospondin in the anthozoan Nematostella vectensis is associated with the nervous system and upregulated during regeneration. Biol Open (2012) 0.77
Molecular and cellular evolution: a celebration of the 200th anniversary of the birth of Charles Darwin. Int J Biochem Cell Biol (2008) 0.75
Nuclear, intradiscal hemangioma. Pain Pract (2008) 0.75