Published in Proc Natl Acad Sci U S A on July 22, 2005
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Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiol Dis (2006) 1.83
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A principal role for the proteasome in endoplasmic reticulum-associated degradation of misfolded intracellular cystic fibrosis transmembrane conductance regulator. J Biol Chem (2002) 1.48
Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. Genome Res (2011) 1.47
Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene. Proc Natl Acad Sci U S A (2008) 1.41
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Complete structure of nuclear rDNA of the obligate plant parasite Plasmodiophora brassicae: intraspecific polymorphisms in the exon and group I intron of the large subunit rDNA. Protist (2011) 1.30
Two subclasses of lung squamous cell carcinoma with different gene expression profiles and prognosis identified by hierarchical clustering and non-negative matrix factorization. Oncogene (2005) 1.28
Application and analysis of the GFPu family of ubiquitin-proteasome system reporters. Methods Enzymol (2005) 1.28
Ubiquitin-specific protease 2 as a tool for quantification of total ubiquitin levels in biological specimens. Anal Biochem (2006) 1.27
A role for mammalian Ubc6 homologues in ER-associated protein degradation. J Cell Sci (2002) 1.26
Structural basis for conformational dynamics of GTP-bound Ras protein. J Biol Chem (2010) 1.26
Crystal structure of M-Ras reveals a GTP-bound "off" state conformation of Ras family small GTPases. J Biol Chem (2005) 1.21
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Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis. J Clin Invest (2002) 1.20
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Suppression of wild-type rhodopsin maturation by mutants linked to autosomal dominant retinitis pigmentosa. J Biol Chem (2004) 1.20
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover. Proc Natl Acad Sci U S A (2013) 1.20
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Impaired post-translational folding of familial ALS-linked Cu, Zn superoxide dismutase mutants. EMBO J (2007) 1.18
Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease. J Cell Biol (2012) 1.18
Kendrin is a novel substrate for separase involved in the licensing of centriole duplication. Curr Biol (2012) 1.14
The mouse polyubiquitin gene Ubb is essential for meiotic progression. Mol Cell Biol (2007) 1.10
Mechanistic studies of substrate-assisted inhibition of ubiquitin-activating enzyme by adenosine sulfamate analogues. J Biol Chem (2011) 1.08
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Recognition of a single transmembrane degron by sequential quality control checkpoints. Mol Biol Cell (2003) 1.00
Centrosome-targeting region of CG-NAP causes centrosome amplification by recruiting cyclin E-cdk2 complex. Genes Cells (2005) 0.98
Recruitment of CG-NAP to the Golgi apparatus through interaction with dynein-dynactin complex. Genes Cells (2007) 0.98
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Mutant protein kinase Cgamma found in spinocerebellar ataxia type 14 is susceptible to aggregation and causes cell death. J Biol Chem (2005) 0.94
Fabrication of a periodic structure with a high refractive-index difference by femtosecond laser pulses. Opt Express (2004) 0.94
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Competition between folding, native-state dimerisation and amyloid aggregation in beta-lactoglobulin. J Mol Biol (2008) 0.92
Phosphorylation and up-regulation of diacylglycerol kinase gamma via its interaction with protein kinase C gamma. J Biol Chem (2006) 0.92
Negative regulation of constitutive NF-kappaB and JNK signaling by PKN1-mediated phosphorylation of TRAF1. Genes Cells (2008) 0.92
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Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease. J Biol Chem (2013) 0.91
Characterization of the ribosomal RNA gene of Kudoa neothunni (Myxosporea: Multivalvulida) in tunas (Thunnus spp.) and Kudoa scomberi n. sp. in a chub mackerel (Scomber japonicus). Parasitol Res (2013) 0.91
A comparative study of the effects of glycerol and hydroxyethyl starch in canine red blood cell cryopreservation. J Vet Med Sci (2004) 0.90
Lbc proto-oncogene product binds to and could be negatively regulated by metastasis suppressor nm23-H2. Biochem Biophys Res Commun (2004) 0.90
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SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells. Biochim Biophys Acta (2009) 0.89
Fibrillar structure and charge determine the interaction of polyglutamine protein aggregates with the cell surface. J Biol Chem (2012) 0.89
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Involvement of a centrosomal protein kendrin in the maintenance of centrosome cohesion by modulating Nek2A kinase activity. Biochem Biophys Res Commun (2010) 0.88
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Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN. J Biochem (2003) 0.87
Simultaneous measurement of amyloid fibril formation by dynamic light scattering and fluorescence reveals complex aggregation kinetics. PLoS One (2013) 0.87
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Plant chitinase as a possible biocontrol agent for use instead of chemical fungicides. Biosci Biotechnol Biochem (2003) 0.85
Critical roles of interactions among switch I-preceding residues and between switch II and its neighboring alpha-helix in conformational dynamics of the GTP-bound Ras family small GTPases. J Biol Chem (2011) 0.84
Protein kinase PKN1 associates with TRAF2 and is involved in TRAF2-NF-kappaB signaling pathway. Biochem Biophys Res Commun (2004) 0.84
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Involvement of protein kinase PKN1 in G2/M delay caused by arsenite. Mol Carcinog (2005) 0.84
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