Published in Curr Biol on July 26, 2005
Exon ligation is proofread by the DExD/H-box ATPase Prp22p. Nat Struct Mol Biol (2006) 2.75
Fidelity at the molecular level: lessons from protein synthesis. Cell (2009) 2.65
Innate immune and chemically triggered oxidative stress modifies translational fidelity. Nature (2009) 2.50
Splice-site pairing is an intrinsically high fidelity process. Proc Natl Acad Sci U S A (2009) 1.44
Differentiating between near- and non-cognate codons in Saccharomyces cerevisiae. PLoS One (2007) 1.17
Shine-Dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the AUG. Proc Natl Acad Sci U S A (2008) 1.08
Misacylation of specific nonmethionyl tRNAs by a bacterial methionyl-tRNA synthetase. Proc Natl Acad Sci U S A (2011) 1.07
Spliceosomes walk the line: splicing errors and their impact on cellular function. RNA Biol (2009) 1.02
Proofreading and spellchecking: a two-tier strategy for pre-mRNA splicing quality control. RNA (2011) 1.00
Large-scale analysis of network bistability for human cancers. PLoS Comput Biol (2010) 0.95
Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism. F1000Prime Rep (2014) 0.88
Conserved discrimination against misacylated tRNAs by two mesophilic elongation factor Tu orthologs. Biochemistry (2008) 0.85
Reprogramming the genetic code: The emerging role of ribosomal frameshifting in regulating cellular gene expression. Bioessays (2015) 0.78
The distribution and query systems of the RCSB Protein Data Bank. Nucleic Acids Res (2004) 7.03
miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science (2012) 4.44
A parsimonious model for gene regulation by miRNAs. Science (2011) 3.79
Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome. Mol Cell (2008) 3.58
An active role for tRNA in decoding beyond codon:anticodon pairing. Science (2005) 3.49
Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol (2010) 3.44
The active site of the ribosome is composed of two layers of conserved nucleotides with distinct roles in peptide bond formation and peptide release. Cell (2004) 3.18
Hypusine-containing protein eIF5A promotes translation elongation. Nature (2009) 2.99
Fidelity at the molecular level: lessons from protein synthesis. Cell (2009) 2.65
Substrate-assisted catalysis of peptide bond formation by the ribosome. Nat Struct Mol Biol (2004) 2.53
The hybrid state of tRNA binding is an authentic translation elongation intermediate. Nat Struct Mol Biol (2006) 2.32
Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay. Science (2010) 2.19
Quality control by the ribosome following peptide bond formation. Nature (2008) 2.15
A genomewide screen for components of the RNAi pathway in Drosophila cultured cells. Proc Natl Acad Sci U S A (2006) 2.04
Translation drives mRNA quality control. Nat Struct Mol Biol (2012) 1.97
Structural basis of highly conserved ribosome recycling in eukaryotes and archaea. Nature (2012) 1.86
Stop codon recognition by release factors induces structural rearrangement of the ribosomal decoding center that is productive for peptide release. Mol Cell (2007) 1.80
Kinetic analysis reveals the ordered coupling of translation termination and ribosome recycling in yeast. Proc Natl Acad Sci U S A (2011) 1.78
The elongation, termination, and recycling phases of translation in eukaryotes. Cold Spring Harb Perspect Biol (2012) 1.73
Ribosomal proteins S12 and S13 function as control elements for translocation of the mRNA:tRNA complex. Mol Cell (2003) 1.71
The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity. RNA (2006) 1.53
Peptide release on the ribosome: mechanism and implications for translational control. Annu Rev Microbiol (2008) 1.48
Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome. J Mol Biol (2007) 1.45
Structural characterization of mRNA-tRNA translocation intermediates. Proc Natl Acad Sci U S A (2012) 1.42
Nevirapine plus efavirenz plus didanosine: a simple, safe, and effective once-daily regimen for patients with HIV infection. J Natl Med Assoc (2003) 1.41
Two distinct components of release factor function uncovered by nucleophile partitioning analysis. Mol Cell (2007) 1.41
Allosteric regulation of Argonaute proteins by miRNAs. Nat Struct Mol Biol (2010) 1.40
Affinity purification of in vivo-assembled ribosomes for in vitro biochemical analysis. Methods (2005) 1.37
Analysis of Dom34 and its function in no-go decay. Mol Biol Cell (2009) 1.37
Mutational analysis reveals two independent molecular requirements during transfer RNA selection on the ribosome. Nat Struct Mol Biol (2006) 1.33
Hyperaccurate and error-prone ribosomes exploit distinct mechanisms during tRNA selection. Mol Cell (2010) 1.32
Multiple effects of S13 in modulating the strength of intersubunit interactions in the ribosome during translation. J Mol Biol (2005) 1.31
EFG-independent translocation of the mRNA:tRNA complex is promoted by modification of the ribosome with thiol-specific reagents. J Mol Biol (2002) 1.24
Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development. Development (2012) 1.22
Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. EMBO J (2008) 1.21
Peptide release on the ribosome depends critically on the 2' OH of the peptidyl-tRNA substrate. RNA (2008) 1.19
An expanded seed sequence definition accounts for full regulation of the hid 3' UTR by bantam miRNA. RNA (2009) 1.17
Transformation of aminoacyl tRNAs for the in vitro selection of "drug-like" molecules. Chem Biol (2004) 1.13
RNA chaperone activity of large ribosomal subunit proteins from Escherichia coli. RNA (2004) 1.11
Structural insights into cognate versus near-cognate discrimination during decoding. EMBO J (2011) 1.07
RNA-based regulation in the plant circadian clock. Trends Plant Sci (2011) 1.05
The 2'-OH group of the peptidyl-tRNA stabilizes an active conformation of the ribosomal PTC. EMBO J (2011) 1.04
A primary role for release factor 3 in quality control during translation elongation in Escherichia coli. Cell (2011) 1.01
Osmolytes stimulate the reconstitution of functional 50S ribosomes from in vitro transcripts of Escherichia coli 23S rRNA. RNA (2002) 1.00
Visualization of codon-dependent conformational rearrangements during translation termination. Nat Struct Mol Biol (2010) 0.99
Regulation of Argonaute slicer activity by guide RNA 3' end interactions with the N-terminal lobe. J Biol Chem (2013) 0.98
Further in vitro exploration fails to support the allosteric three-site model. J Biol Chem (2012) 0.97
Distinct response of yeast ribosomes to a miscoding event during translation. RNA (2011) 0.96
Recommendations on bioanalytical method stability implications of co-administered and co-formulated drugs by Global CRO Council for Bioanalysis (GCC). Bioanalysis (2012) 0.94
Helix 69 is key for uniformity during substrate selection on the ribosome. J Biol Chem (2011) 0.91
Kinetic basis for global loss of fidelity arising from mismatches in the P-site codon:anticodon helix. RNA (2010) 0.90
The role of SmpB and the ribosomal decoding center in licensing tmRNA entry into stalled ribosomes. RNA (2011) 0.90
Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors: a single-institution experience. J Clin Apher (2010) 0.89
Dom34-Hbs1 mediated dissociation of inactive 80S ribosomes promotes restart of translation after stress. EMBO J (2014) 0.89
Isolation of antibiotic resistance mutations in the rRNA by using an in vitro selection system. Proc Natl Acad Sci U S A (2004) 0.89
Eukaryotic release factor 3 is required for multiple turnovers of peptide release catalysis by eukaryotic release factor 1. J Biol Chem (2013) 0.89
Functional elucidation of a key contact between tRNA and the large ribosomal subunit rRNA during decoding. RNA (2010) 0.88
Ribosomal translocation: sparsomycin pushes the button. Curr Biol (2003) 0.88
RF3:GTP promotes rapid dissociation of the class 1 termination factor. RNA (2014) 0.87
Wobble during decoding: more than third-position promiscuity. Nat Struct Mol Biol (2004) 0.85
The psychosocial aspects of donating blood stem cells: the sibling donor perspective. J Clin Apher (2003) 0.85
Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B. RNA (2011) 0.85
Extracorporeal photopheresis improves nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis: three case reports and review of literature. J Clin Apher (2008) 0.82
Epicardial adipose tissue thickness as a predictor of impaired microvascular function in patients with non-obstructive coronary artery disease. J Nucl Cardiol (2013) 0.82
In vitro transcription from plasmid or PCR-amplified DNA. Methods Enzymol (2013) 0.81
Efficient asymmetric synthesis of chiral hydroxy-gamma-butyrolactones. Org Lett (2009) 0.80
Biochemistry. Getting past polyproline pauses. Science (2013) 0.79
Structural analysis of RNA backbone using in-line probing. Methods Enzymol (2013) 0.79
Recommendations on biomarker bioanalytical method validation by GCC. Bioanalysis (2012) 0.79
Ribosomal translocation: LepA does it backwards. Curr Biol (2007) 0.78
Recommendations on the interpretation of the new European Medicines Agency Guideline on Bioanalytical Method Validation by Global CRO Council for Bioanalysis (GCC). Bioanalysis (2012) 0.78
High affinity ligands for the alpha7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor. Bioorg Med Chem Lett (2005) 0.78
Polysome analysis of mammalian cells. Methods Enzymol (2013) 0.78
A Role for the 2' OH of peptidyl-tRNA substrate in peptide release on the ribosome revealed through RF-mediated rescue. Chem Biol (2012) 0.77
Another burst of smoke: atomic resolution structures of RF3 bound to the ribosome. RNA (2012) 0.75
Northern blotting. Methods Enzymol (2013) 0.75
Conference report: the 3rd Global CRO Council for Bioanalysis at the International Reid Bioanalytical Forum. Bioanalysis (2011) 0.75
Corrigendum: Rapid generation of hypomorphic mutations. Nat Commun (2017) 0.75
Recommendations on ISR in multi analyte assays, QA/bioanalytical consultants and GCP by Global CRO Council for Bioanalysis (GCC). Bioanalysis (2012) 0.75
The survive and thrive program: encouraging coaching, mentoring, and peer learning among new local health officials. J Public Health Manag Pract (2010) 0.75