Published in Am J Physiol Gastrointest Liver Physiol on August 04, 2005
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest (2007) 4.09
Retracted Ferroportin in the progression and prognosis of hepatocellular carcinoma. Eur J Med Res (2013) 1.43
The iron efflux protein ferroportin regulates the intracellular growth of Salmonella enterica. Infect Immun (2006) 1.38
Wild-type and mutant ferroportins do not form oligomers in transfected cells. Biochem J (2006) 1.12
Liver iron transport. World J Gastroenterol (2007) 1.08
Role of hepcidin in the setting of hypoferremia during acute inflammation. PLoS One (2013) 1.06
Erythropoiesis and iron sulfur cluster biogenesis. Adv Hematol (2010) 0.99
beta-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload. Adv Hematol (2010) 0.98
Subcellular localization of iron and heme metabolism related proteins at early stages of erythrophagocytosis. PLoS One (2012) 0.92
Iron metabolism: current facts and future directions. Biochem Med (Zagreb) (2012) 0.92
Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections. Proc Natl Acad Sci U S A (2014) 0.91
Ironing out Ferroportin. Cell Metab (2015) 0.90
Ferroportin 1 is expressed basolaterally in rat kidney proximal tubule cells and iron excess increases its membrane trafficking. J Cell Mol Med (2011) 0.89
Transplantation of allogeneic T cells alters iron homeostasis in NOD/SCID mice. Blood (2008) 0.87
Molecular mechanisms involved in intestinal iron absorption. World J Gastroenterol (2007) 0.87
Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages. Haematologica (2010) 0.86
Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2α and altered expression of iron absorption genes in mice. PLoS One (2013) 0.85
Iron transport machinery of human cells: players and their interactions. Curr Top Membr (2012) 0.82
Effect of erythropoietin on hepcidin, DMT1 with IRE, and hephaestin gene expression in duodenum of rats. J Gastroenterol (2008) 0.81
Ferroportin and erythroid cells: an update. Adv Hematol (2010) 0.81
Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo. PLoS One (2013) 0.80
Allogeneic transplantation, Fas signaling, and dysregulation of hepcidin. Biol Blood Marrow Transplant (2013) 0.80
Computational modeling and analysis of iron release from macrophages. PLoS Comput Biol (2014) 0.79
Hepcidin bound to α2-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels. J Biol Chem (2013) 0.79
Recent advances in small bowel diseases: Part II. World J Gastroenterol (2012) 0.78
Immunolocalization of ferroportin in healthy and anemic mice. J Histochem Cytochem (2008) 0.77
Iron regulates the expression of ferroportin 1 in the cultured hFOB 1.19 osteoblast cell line. Exp Ther Med (2014) 0.76
Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection. Front Immunol (2017) 0.75
Non-mutagenic Suppression of Enterocyte Ferroportin 1 by Chemical Ribosomal Inactivation via p38 Mitogen-activated Protein Kinase (MAPK)-mediated Regulation: EVIDENCE FOR ENVIRONMENTAL HEMOCHROMATOSIS. J Biol Chem (2016) 0.75
Human macrophage ferroportin biology and the basis for the Ferroportin Disease. Hepatology (2016) 0.75
Iron Homeostasis and Inflammatory Status in Mice Deficient for the Cystic Fibrosis Transmembrane Regulator. PLoS One (2015) 0.75
Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption. PLoS One (2017) 0.75
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science (2004) 19.19
Antimicrobial drug discovery through bacteriophage genomics. Nat Biotechnol (2004) 4.17
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity (2010) 3.96
The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proc Natl Acad Sci U S A (2005) 3.84
Mutations in VANGL1 associated with neural-tube defects. N Engl J Med (2007) 3.58
IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med (2011) 3.29
Mitoferrin is essential for erythroid iron assimilation. Nature (2006) 2.99
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat Genet (2002) 2.83
Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science (2008) 2.59
Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages. J Bacteriol (2006) 2.18
Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency. Science (2012) 2.06
Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A (2008) 1.90
Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family. J Biol Chem (2004) 1.90
The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation. J Immunol (2007) 1.89
A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice. J Exp Med (2005) 1.74
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J Immunol (2008) 1.73
The cell growth suppressor, mir-126, targets IRS-1. Biochem Biophys Res Commun (2008) 1.73
Pyruvate kinase deficiency and malaria. N Engl J Med (2008) 1.72
ALAS2 acts as a modifier gene in patients with congenital erythropoietic porphyria. Blood (2011) 1.68
Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane. Blood (2003) 1.63
Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. PLoS Pathog (2013) 1.59
Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages. J Biol Chem (2006) 1.55
Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet (2003) 1.40
The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA. J Biol Chem (2003) 1.40
Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes. Proc Natl Acad Sci U S A (2002) 1.39
A common genetic fingerprint in leprosy and Crohn's disease? N Engl J Med (2009) 1.39
C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. J Exp Med (2008) 1.38
Pyruvate kinase deficiency in mice protects against malaria. Nat Genet (2003) 1.38
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Mol Biol Cell (2005) 1.37
Novel mutations in VANGL1 in neural tube defects. Hum Mutat (2009) 1.37
Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice. J Exp Med (2003) 1.37
Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates. Trends Genet (2004) 1.36
Ferroportin1 is required for normal iron cycling in zebrafish. J Clin Invest (2005) 1.27
A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus. Bioorg Med Chem (2006) 1.23
Erythrocyte variants and the nature of their malaria protective effect. Cell Microbiol (2005) 1.22
Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens. J Immunol (2007) 1.18
Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila. Cell Microbiol (2006) 1.17
Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus. J Exp Med (2007) 1.16
Dysregulated inflammatory response to Candida albicans in a C5-deficient mouse strain. Infect Immun (2004) 1.15
Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. J Biol Chem (2001) 1.15
Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. J Exp Med (2013) 1.14
Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cell Microbiol (2008) 1.13
Wild-type and mutant ferroportins do not form oligomers in transfected cells. Biochem J (2006) 1.12
Evidence for additive and interaction effects of host genotype and infection in malaria. Proc Natl Acad Sci U S A (2012) 1.11
Naip5/Birc1e and susceptibility to Legionella pneumophila. Trends Microbiol (2005) 1.11
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infect Immun (2009) 1.08
Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs. Proc Natl Acad Sci U S A (2003) 1.07
Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens. Diabetes (2008) 1.06
Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J Biol Chem (2003) 1.06
Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells. Cancer Res (2008) 1.05
Expression and subcellular localization of NRAMP1 in human neutrophil granules. Blood (2002) 1.05
TB: screening for responses to a vile visitor. Cell (2010) 1.05
Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Hum Mol Genet (2011) 1.04
Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice. Infect Immun (2007) 1.04
Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8. J Immunol (2009) 1.04
Opsonin-independent phagocytosis: an effector mechanism against acute blood-stage Plasmodium chabaudi AS infection. J Infect Dis (2002) 1.04
Iron transport by Nramp2/DMT1: pH regulation of transport by 2 histidines in transmembrane domain 6. Blood (2003) 1.03
Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2). Biochemistry (2006) 1.02
Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. PLoS Genet (2011) 1.02
Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes. Biochemistry (2005) 1.02
Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice. Kidney Int (2002) 1.01
Cerebral malaria: human versus mouse studies. Trends Parasitol (2010) 1.01
Effect of Nramp1 on bacterial replication and on maturation of Mycobacterium avium-containing phagosomes in bone marrow-derived mouse macrophages. Cell Microbiol (2002) 1.00
VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish. Mech Dev (2010) 0.99
Recycling iron in normal and pathological states. Semin Hematol (2009) 0.99
Primitive neuroectodermal tumor of the stomach. Arch Pathol Lab Med (2005) 0.98
Host resistance to malaria: using mouse models to explore the host response. Mamm Genome (2010) 0.98
Genetic control of myeloproliferation in BXH-2 mice. Blood (2003) 0.98
Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse. Biochemistry (2010) 0.97
Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice. J Exp Med (2007) 0.97
Host immune response to Salmonella enterica serovar Typhimurium infection in mice derived from wild strains. Infect Immun (2002) 0.95
Genetic control of susceptibility to bacterial infections in mouse models. Cell Microbiol (2003) 0.94
Loss of membrane targeting of Vangl proteins causes neural tube defects. Biochemistry (2011) 0.93
[Detection of cell apoptosis in the pathological tissues of patients with SARS and its significance]. Di Yi Jun Yi Da Xue Xue Bao (2003) 0.93
Genetic and genomic analyses of host-pathogen interactions in malaria. Trends Parasitol (2009) 0.92
Single gene effects in mouse models of host: pathogen interactions. J Leukoc Biol (2005) 0.92
Influence of Slc11a1 on the outcome of Salmonella enterica serovar Enteritidis infection in mice is associated with Th polarization. Infect Immun (2006) 0.92
Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6). Biochemistry (2002) 0.91
The C3H/HeJ inbred mouse is a model of vesico-ureteric reflux with a susceptibility locus on chromosome 12. Kidney Int (2010) 0.91
Hepcidin regulates intrarenal iron handling at the distal nephron. Kidney Int (2013) 0.90
Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells. Blood (2002) 0.89
Intracellular Leishmania: your iron or mine? Trends Microbiol (2007) 0.89
Triaminotriazine DNA helicase inhibitors with antibacterial activity. Bioorg Med Chem Lett (2005) 0.89
Transmembrane topology of the mammalian Slc11a2 iron transporter. Biochemistry (2009) 0.89
[Cellular angiofibroma, angiomyofibroblastoma and aggressive angiomyxoma: members of a spectrum of genital stromal tumours?]. Ann Pathol (2002) 0.89
Interleukin-15 enhances innate and adaptive immune responses to blood-stage malaria infection in mice. Infect Immun (2005) 0.89
A novel R416C mutation in human DMT1 (SLC11A2) displays pleiotropic effects on function and causes microcytic anemia and hepatic iron overload. Blood Cells Mol Dis (2006) 0.88
Cardiac failure in C5-deficient A/J mice after Candida albicans infection. Infect Immun (2006) 0.88
A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene. Dev Dyn (2011) 0.88
Conformational change induced by ATP binding in the multidrug ATP-binding cassette transporter BmrA. Biochemistry (2008) 0.88
Genetic control of susceptibility to infection with Candida albicans in mice. PLoS One (2011) 0.88
A two-locus system controls susceptibility to colitis-associated colon cancer in mice. Oncotarget (2010) 0.88
Current and future use of "dried blood spot" analyses in clinical chemistry. Clin Chem Lab Med (2013) 0.87
[Detection of severe acute respiratory syndrome (SARS)-associated coronavirus RNA in autopsy tissues with in situ hybridization]. Di Yi Jun Yi Da Xue Xue Bao (2003) 0.87
Rescue of the neural tube defect of loop-tail mice by a BAC clone containing the Ltap gene. Genomics (2003) 0.87
Total diet study on pesticide residues in France: levels in food as consumed and chronic dietary risk to consumers. Environ Int (2012) 0.87
Molecular and cellular mechanisms underlying iron transport deficiency in microcytic anemia. Blood (2004) 0.86
Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. J Infect Dis (2009) 0.86
Iron chelators modulate the fusogenic properties of Salmonella-containing phagosomes. Proc Natl Acad Sci U S A (2003) 0.86
Functional characterization of the E399D DMT1/NRAMP2/SLC11A2 protein produced by an exon 12 mutation in a patient with microcytic anemia and iron overload. Blood Cells Mol Dis (2005) 0.85