Published in Proc Natl Acad Sci U S A on September 04, 2012
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Transcriptional changes induced by candidate malaria vaccines and correlation with protection against malaria in a human challenge model. Vaccine (2015) 0.80
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Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya. BMC Infect Dis (2017) 0.75
Genetic and transcriptional analysis of human host response to healthy gut microbiota. mSystems (2016) 0.75
Genetic evidence for erythrocyte receptor glycophorin B expression levels defining a dominant Plasmodium falciparum invasion pathway into human erythrocytes. Infect Immun (2017) 0.75
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A whole-genome association study of major determinants for host control of HIV-1. Science (2007) 15.19
Discovery and characterization of chromatin states for systematic annotation of the human genome. Nat Biotechnol (2010) 9.84
Genomewide association study of leprosy. N Engl J Med (2009) 8.17
Systems biology of vaccination for seasonal influenza in humans. Nat Immunol (2011) 6.09
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Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
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Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nat Genet (2010) 2.73
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A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature (2011) 2.58
A systematic statistical linear modeling approach to oligonucleotide array experiments. Math Biosci (2002) 2.53
Geographical genomics of human leukocyte gene expression variation in southern Morocco. Nat Genet (2009) 2.38
Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. Nat Genet (2010) 2.32
Genetic analysis of radiation-induced changes in human gene expression. Nature (2009) 2.30
A genome-wide gene expression signature of environmental geography in leukocytes of Moroccan Amazighs. PLoS Genet (2008) 2.19
Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria. Proc Natl Acad Sci U S A (2008) 1.86
Nutritional modulation of malaria morbidity and mortality. J Infect Dis (2000) 1.81
Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A (2012) 1.73
Systems genetics analysis of gene-by-environment interactions in human cells. Am J Hum Genet (2010) 1.69
Genomewide analysis of the host response to malaria in Kenyan children. J Infect Dis (2005) 1.66
Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-gamma expression in activated human T cells. J Leukoc Biol (2009) 1.50
BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells. PLoS Biol (2007) 1.49
Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes. PLoS Genet (2011) 1.49
Human SCO2 is required for the synthesis of CO II and as a thiol-disulphide oxidoreductase for SCO1. Hum Mol Genet (2009) 1.45
Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants. Am J Hum Genet (2007) 1.39
Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria. Infect Immun (2006) 1.33
Fcgamma receptor IIA and IIIB polymorphisms are associated with susceptibility to cerebral malaria. Parasitol Int (2002) 1.30
Major reduction of malaria morbidity with combined vitamin A and zinc supplementation in young children in Burkina Faso: a randomized double blind trial. Nutr J (2008) 1.15
Genetics of susceptibility to Plasmodium falciparum: from classical malaria resistance genes towards genome-wide association studies. Parasite Immunol (2009) 1.06
Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange. Eur J Immunol (2010) 1.04
Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity. J Immunol (2011) 0.98
Host resistance to malaria: using mouse models to explore the host response. Mamm Genome (2010) 0.98
Molecular correlates of experimental cerebral malaria detectable in whole blood. Infect Immun (2010) 0.86
Clinical and molecular aspects of malaria fever. Trends Parasitol (2011) 0.82
Polymorphisms of transporter associated with antigen processing type 1 (TAP1), proteasome subunit beta type 9 (PSMB9) and their common promoter in African children with different manifestations of malaria. Int J Immunogenet (2005) 0.81
Variation in genome-wide mutation rates within and between human families. Nat Genet (2011) 8.84
A coalescent-based method for detecting and estimating recombination from gene sequences. Genetics (2002) 7.41
Antimicrobial drug discovery through bacteriophage genomics. Nat Biotechnol (2004) 4.17
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity (2010) 3.96
The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proc Natl Acad Sci U S A (2005) 3.84
Mutations in VANGL1 associated with neural-tube defects. N Engl J Med (2007) 3.58
Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome. Nat Genet (2006) 3.45
IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med (2011) 3.29
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci U S A (2010) 3.13
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat Genet (2002) 2.83
Recombination hotspots and population structure in Plasmodium falciparum. PLoS Biol (2005) 2.67
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs. Nat Genet (2010) 2.48
Large-scale population structure of human commensal Escherichia coli isolates. Appl Environ Microbiol (2004) 2.29
Global genetic diversity and evolution of var genes associated with placental and severe childhood malaria. Mol Biochem Parasitol (2006) 2.24
Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages. J Bacteriol (2006) 2.18
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans. J Exp Med (2011) 2.09
Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency. Science (2012) 2.06
Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4. Am J Hum Genet (2010) 2.05
Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations. Am J Clin Nutr (2006) 1.98
Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A (2008) 1.90
Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family. J Biol Chem (2004) 1.90
The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation. J Immunol (2007) 1.89
Canonical WNT signaling during kidney development. Am J Physiol Renal Physiol (2007) 1.87
Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA. Mol Biochem Parasitol (2007) 1.86
The mouse Gene Expression Database (GXD): 2014 update. Nucleic Acids Res (2013) 1.78
A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice. J Exp Med (2005) 1.74
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J Immunol (2008) 1.73
Pyruvate kinase deficiency and malaria. N Engl J Med (2008) 1.72
High-resolution genomic analysis of human mitochondrial RNA sequence variation. Science (2014) 1.71
Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane. Blood (2003) 1.63
Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. PLoS Pathog (2013) 1.59
Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines. Proc Natl Acad Sci U S A (2011) 1.56
Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages. J Biol Chem (2006) 1.55
Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila. Curr Biol (2006) 1.49
LGL1, a novel branching morphogen in developing kidney, is induced by retinoic acid. Am J Physiol Renal Physiol (2007) 1.45
Exome sequencing identifies mutations in the gene TTC7A in French-Canadian cases with hereditary multiple intestinal atresia. J Med Genet (2013) 1.44
Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus. PLoS Biol (2004) 1.41
The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA. J Biol Chem (2003) 1.40
Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes. Proc Natl Acad Sci U S A (2002) 1.39
A common genetic fingerprint in leprosy and Crohn's disease? N Engl J Med (2009) 1.39
Pyruvate kinase deficiency in mice protects against malaria. Nat Genet (2003) 1.38
C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. J Exp Med (2008) 1.38
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Mol Biol Cell (2005) 1.37
Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice. J Exp Med (2003) 1.37
Novel mutations in VANGL1 in neural tube defects. Hum Mutat (2009) 1.37
Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates. Trends Genet (2004) 1.36
Rare copy number variants contribute to congenital left-sided heart disease. PLoS Genet (2012) 1.35
Plasmodium falciparum genetic diversity maintained and amplified over 5 years of a low transmission endemic in the Peruvian Amazon. Mol Biol Evol (2010) 1.33
Retracted Darwinian selection on a selfing locus. Science (2004) 1.29
CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction. PLoS Pathog (2012) 1.28
High recombination rates and hotspots in a Plasmodium falciparum genetic cross. Genome Biol (2011) 1.27
Comparative studies of duodenal and macrophage ferroportin proteins. Am J Physiol Gastrointest Liver Physiol (2005) 1.25
Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome. Mol Biol Evol (2010) 1.23
A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus. Bioorg Med Chem (2006) 1.23
Erythrocyte variants and the nature of their malaria protective effect. Cell Microbiol (2005) 1.22
The FimH A27V mutation is pathoadaptive for urovirulence in Escherichia coli B2 phylogenetic group isolates. Infect Immun (2003) 1.18
Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens. J Immunol (2007) 1.18
Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila. Cell Microbiol (2006) 1.17
Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors. PLoS One (2011) 1.16
Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus. J Exp Med (2007) 1.16
Dysregulated inflammatory response to Candida albicans in a C5-deficient mouse strain. Infect Immun (2004) 1.15
Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. J Biol Chem (2001) 1.15
Diversity and linkage of genes in the self-incompatibility gene family in Arabidopsis lyrata. Genetics (2003) 1.14
Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. J Exp Med (2013) 1.14
Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cell Microbiol (2008) 1.13
A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection. BMC Genomics (2006) 1.12
Naip5/Birc1e and susceptibility to Legionella pneumophila. Trends Microbiol (2005) 1.11
An X-linked haplotype of Neandertal origin is present among all non-African populations. Mol Biol Evol (2011) 1.11
Rare allelic forms of PRDM9 associated with childhood leukemogenesis. Genome Res (2012) 1.09
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infect Immun (2009) 1.08
A population genetic approach to mapping neurological disorder genes using deep resequencing. PLoS Genet (2011) 1.07
Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs. Proc Natl Acad Sci U S A (2003) 1.07
Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens. Diabetes (2008) 1.06
Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J Biol Chem (2003) 1.06
Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells. Cancer Res (2008) 1.05
Expression and subcellular localization of NRAMP1 in human neutrophil granules. Blood (2002) 1.05
TB: screening for responses to a vile visitor. Cell (2010) 1.05
Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Hum Mol Genet (2011) 1.04
Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice. Infect Immun (2007) 1.04
Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8. J Immunol (2009) 1.04
Opsonin-independent phagocytosis: an effector mechanism against acute blood-stage Plasmodium chabaudi AS infection. J Infect Dis (2002) 1.04
Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans. PLoS Genet (2013) 1.03
Iron transport by Nramp2/DMT1: pH regulation of transport by 2 histidines in transmembrane domain 6. Blood (2003) 1.03
Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection. Blood (2012) 1.03
Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2). Biochemistry (2006) 1.02