Published in Curr Opin Genet Dev on October 01, 2005
Metabolism and cancer: the circadian clock connection. Nat Rev Cancer (2009) 2.91
PER2 controls lipid metabolism by direct regulation of PPARγ. Cell Metab (2010) 1.91
The circadian clock and pathology of the ageing brain. Nat Rev Neurosci (2012) 1.90
A genomic view of the sea urchin nervous system. Dev Biol (2006) 1.68
Molecular and phylogenetic analyses reveal mammalian-like clockwork in the honey bee (Apis mellifera) and shed new light on the molecular evolution of the circadian clock. Genome Res (2006) 1.68
Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein. Proc Natl Acad Sci U S A (2006) 1.63
Mammalian circadian clock and metabolism - the epigenetic link. J Cell Sci (2010) 1.55
The BMAL1 C terminus regulates the circadian transcription feedback loop. Proc Natl Acad Sci U S A (2006) 1.41
Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression. Biochem J (2007) 1.27
Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1. Aging (Albany NY) (2009) 1.14
Circadian control by the reduction/oxidation pathway: catalase represses light-dependent clock gene expression in the zebrafish. Proc Natl Acad Sci U S A (2007) 1.11
Estrogen directly modulates circadian rhythms of PER2 expression in the uterus. Am J Physiol Endocrinol Metab (2008) 1.09
Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription. J Biol Chem (2009) 1.08
Heme-based sensing by the mammalian circadian protein CLOCK. Inorg Chem (2010) 0.93
Phylogeny and oscillating expression of period and cryptochrome in short and long photoperiods suggest a conserved function in Nasonia vitripennis. Chronobiol Int (2014) 0.82
Cloning, tissue expression pattern and daily rhythms of Period1, Period2, and Clock transcripts in the flatfish Senegalese sole, Solea senegalensis. J Comp Physiol B (2012) 0.81
Involvement of stress kinase mitogen-activated protein kinase kinase 7 in regulation of mammalian circadian clock. J Biol Chem (2012) 0.80
Circadian rhythms lit up in Chlamydomonas. Genome Biol (2006) 0.80
Clock T3111C and Per2 C111G SNPs do not influence circadian rhythmicity in healthy Italian population. Neurol Sci (2010) 0.80
Quantitative analysis of cellular metabolic dissipative, self-organized structures. Int J Mol Sci (2010) 0.78
Daily rhythmicity of clock gene transcript levels in fast and slow muscle fibers from Chinese perch (Siniperca chuatsi). BMC Genomics (2016) 0.75
Identification of the Molecular Clockwork of the Oyster Crassostrea gigas. PLoS One (2017) 0.75
Melatonin, clock genes and mitochondria in sepsis. Cell Mol Life Sci (2017) 0.75
An ancestral haplotype of the human PERIOD2 gene associates with reduced sensitivity to light-induced melatonin suppression. PLoS One (2017) 0.75
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell (2008) 6.44
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science (2009) 5.35
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell (2004) 5.27
Circadian regulator CLOCK is a histone acetyltransferase. Cell (2006) 5.24
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol (2002) 4.50
A web of circadian pacemakers. Cell (2002) 4.39
Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23
Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity. Proc Natl Acad Sci U S A (2002) 3.03
Metabolism and cancer: the circadian clock connection. Nat Rev Cancer (2009) 2.91
The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components. Proc Natl Acad Sci U S A (2006) 2.75
CLOCK-mediated acetylation of BMAL1 controls circadian function. Nature (2007) 2.65
Chromatin remodelling and epigenetic features of germ cells. Nature (2005) 2.49
Circadian clock control by SUMOylation of BMAL1. Science (2005) 2.30
Coordination of the transcriptome and metabolome by the circadian clock. Proc Natl Acad Sci U S A (2012) 2.22
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage. Cell Cycle (2006) 2.17
The chromatoid body: a germ-cell-specific RNA-processing centre. Nat Rev Mol Cell Biol (2007) 2.15
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression. Nat Struct Mol Biol (2010) 2.00
Metabolism control by the circadian clock and vice versa. Nat Struct Mol Biol (2009) 1.99
PER2 controls lipid metabolism by direct regulation of PPARγ. Cell Metab (2010) 1.91
Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis. Nat Methods (2004) 1.91
RNA granules in germ cells. Cold Spring Harb Perspect Biol (2011) 1.80
Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5. Blood (2008) 1.80
Connecting threads: epigenetics and metabolism. Cell (2012) 1.75
Phenotypic rescue of a peripheral clock genetic defect via SCN hierarchical dominance. Cell (2002) 1.71
Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons. J Cell Sci (2003) 1.70
Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance. Proc Natl Acad Sci U S A (2013) 1.64
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1. Proc Natl Acad Sci U S A (2003) 1.64
Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis. Proc Natl Acad Sci U S A (2005) 1.59
Mammalian circadian clock and metabolism - the epigenetic link. J Cell Sci (2010) 1.55
Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells. J Cell Sci (2006) 1.52
Bindarit: an anti-inflammatory small molecule that modulates the NFκB pathway. Cell Cycle (2012) 1.51
Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD. Mol Cell (2005) 1.51
Riding tandem: circadian clocks and the cell cycle. Cell (2007) 1.49
Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM. Exp Cell Res (2002) 1.48
Metabolism and the circadian clock converge. Physiol Rev (2013) 1.47
Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation. PLoS One (2010) 1.44
Plasticity and specificity of the circadian epigenome. Nat Neurosci (2010) 1.41
Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids. Development (2002) 1.37
Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism. Mol Cell Biol (2010) 1.35
Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family. Mol Endocrinol (2002) 1.34
Chromatin remodeling, metabolism and circadian clocks: the interplay of CLOCK and SIRT1. Int J Biochem Cell Biol (2008) 1.33
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. Proc Natl Acad Sci U S A (2006) 1.32
Regulation of metabolism: the circadian clock dictates the time. Trends Endocrinol Metab (2011) 1.32
Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor. FASEB J (2004) 1.30
The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation. J Cell Sci (2003) 1.30
Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis. Mol Endocrinol (2006) 1.30
Signaling to the circadian clock: plasticity by chromatin remodeling. Curr Opin Cell Biol (2007) 1.30
Light induction of a vertebrate clock gene involves signaling through blue-light receptors and MAP kinases. Curr Biol (2002) 1.23
CK2alpha phosphorylates BMAL1 to regulate the mammalian clock. Nat Struct Mol Biol (2009) 1.23
Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock. Proc Natl Acad Sci U S A (2010) 1.20
CREM-dependent transcription in male germ cells controlled by a kinesin. Science (2002) 1.20
Testis-specific transcription mechanisms promoting male germ-cell differentiation. Reproduction (2004) 1.16
Common pathways in circadian and cell cycle clocks: light-dependent activation of Fos/AP-1 in zebrafish controls CRY-1a and WEE-1. Proc Natl Acad Sci U S A (2005) 1.16
Circadian clock and breast cancer: a molecular link. Cell Cycle (2007) 1.14
DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation. Mol Endocrinol (2003) 1.14
CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics. Nat Methods (2012) 1.14
Role of glucocorticoids and cAMP-mediated repression in limiting corticotropin-releasing hormone transcription during stress. J Neurosci (2005) 1.14
Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis. Proc Natl Acad Sci U S A (2006) 1.13
A direct role of SRY and SOX proteins in pre-mRNA splicing. Proc Natl Acad Sci U S A (2002) 1.12
No circadian rhythms in testis: Period1 expression is clock independent and developmentally regulated in the mouse. Mol Endocrinol (2003) 1.12
Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells. BMC Genomics (2010) 1.12
Circadian control by the reduction/oxidation pathway: catalase represses light-dependent clock gene expression in the zebrafish. Proc Natl Acad Sci U S A (2007) 1.11
Mouse Period1 (mPER1) acts as a circadian adaptor to entrain the oscillator to environmental light/dark cycles by regulating mPER2 protein. J Neurosci (2005) 1.11
Circadian acetylome reveals regulation of mitochondrial metabolic pathways. Proc Natl Acad Sci U S A (2013) 1.11
The circadian clock: a framework linking metabolism, epigenetics and neuronal function. Nat Rev Neurosci (2012) 1.08
Circadian clock regulates the host response to Salmonella. Proc Natl Acad Sci U S A (2013) 1.07
Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages. Mol Pharmacol (2011) 1.07
A small C-terminal sequence of Aurora B is responsible for localization and function. Mol Biol Cell (2004) 1.07
Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage. Proc Natl Acad Sci U S A (2005) 1.05
The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners. Mol Cell Biol (2005) 1.04
Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation. Dev Biol (2008) 1.03
Environmental stimulus perception and control of circadian clocks. Curr Opin Neurobiol (2002) 1.02
Temporal association of protamine 1 with the inner nuclear membrane protein lamin B receptor during spermiogenesis. J Biol Chem (2003) 1.01
Regulation of gene expression in post-meiotic male germ cells: CREM-signalling pathways and male fertility. Hum Fertil (Camb) (2006) 1.00
Light-inducible and clock-controlled expression of MAP kinase phosphatase 1 in mouse central pacemaker neurons. J Biol Rhythms (2007) 1.00
Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1. Proc Natl Acad Sci U S A (2013) 1.00
Production of fertile offspring from genetically infertile male mice. Proc Natl Acad Sci U S A (2004) 0.99
Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation. Aging (Albany NY) (2011) 0.98
Negative control of circadian clock regulator E4BP4 by casein kinase Iepsilon-mediated phosphorylation. Curr Biol (2004) 0.98
The circadian epigenome: how metabolism talks to chromatin remodeling. Curr Opin Cell Biol (2013) 0.98
X-linked adrenal hypoplasia congenita is caused by abnormal nuclear localization of the DAX-1 protein. Proc Natl Acad Sci U S A (2002) 0.98
Joining the dots: from chromatin remodeling to neuronal plasticity. Curr Opin Neurobiol (2010) 0.97
The circadian clock transcriptional complex: metabolic feedback intersects with epigenetic control. Ann N Y Acad Sci (2012) 0.96
Cycles in spatial and temporal chromosomal organization driven by the circadian clock. Nat Struct Mol Biol (2013) 0.96
The epigenetic language of circadian clocks. Handb Exp Pharmacol (2013) 0.95
Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene. Proc Natl Acad Sci U S A (2004) 0.95
Unraveling the mechanisms of the vertebrate circadian clock: zebrafish may light the way. Bioessays (2002) 0.94
SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression. Epigenetics (2012) 0.92
Time after time: inputs to and outputs from the mammalian circadian oscillators. Trends Neurosci (2002) 0.92
Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells. J Cell Sci (2012) 0.92
The chromatoid body of male germ cells: epigenetic control and miRNA pathway. Cell Cycle (2008) 0.91
Common light signaling pathways controlling DNA repair and circadian clock entrainment in zebrafish. Cell Cycle (2009) 0.91
ROS stress resets circadian clocks to coordinate pro-survival signals. PLoS One (2013) 0.91
Impaired light masking in dopamine D2 receptor-null mice. Nat Neurosci (2006) 0.90
Microtubule-independent and protein kinase A-mediated function of kinesin KIF17b controls the intracellular transport of activator of CREM in testis (ACT). J Biol Chem (2005) 0.89
Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes. Cell Mol Life Sci (2009) 0.89
Circadian clocks, epigenetics, and cancer. Curr Opin Oncol (2015) 0.89
Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1. J Biol Chem (2014) 0.89
Impact papers on aging in 2009. Aging (Albany NY) (2010) 0.89
CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver. Biochem Biophys Res Commun (2008) 0.89