The circadian clock: a framework linking metabolism, epigenetics and neuronal function.

PubWeight™: 1.08‹?› | Rank: Top 10%

🔗 View Article (PMID 23187814)

Published in Nat Rev Neurosci on November 28, 2012

Authors

Selma Masri1, Paolo Sassone-Corsi

Author Affiliations

1: Department of Biological Chemistry, Center for Epigenetics and Metabolism, School of Medicine, University of California, Irvine, California 92697, USA.

Articles citing this

Local receptors as novel regulators for peripheral clock expression. FASEB J (2014) 1.42

Translational profiling of clock cells reveals circadianly synchronized protein synthesis. PLoS Biol (2013) 1.08

Analysis of clock-regulated genes in Neurospora reveals widespread posttranscriptional control of metabolic potential. Proc Natl Acad Sci U S A (2014) 1.00

Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan. Cell Metab (2016) 0.95

The circadian clock and cell cycle: interconnected biological circuits. Curr Opin Cell Biol (2013) 0.89

Transcriptional program of Kpna2/Importin-α2 regulates cellular differentiation-coupled circadian clock development in mammalian cells. Proc Natl Acad Sci U S A (2014) 0.83

Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder. Mol Psychiatry (2014) 0.83

Epigenetics of sleep and chronobiology. Curr Neurol Neurosci Rep (2014) 0.80

The Circadian Clock in the Ventromedial Hypothalamus Controls Cyclic Energy Expenditure. Cell Metab (2016) 0.80

Minutes, days and years: molecular interactions among different scales of biological timing. Philos Trans R Soc Lond B Biol Sci (2014) 0.79

Back to the future: transgenerational transmission of xenobiotic-induced epigenetic remodeling. Epigenetics (2015) 0.78

Effect of Resveratrol, a SIRT1 Activator, on the Interactions of the CLOCK/BMAL1 Complex. Endocrinol Metab (Seoul) (2014) 0.78

The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways. Aging (Albany NY) (2016) 0.77

Clock genes × stress × reward interactions in alcohol and substance use disorders. Alcohol (2015) 0.77

Altered dynamics in the circadian oscillation of clock genes in dermal fibroblasts of patients suffering from idiopathic hypersomnia. PLoS One (2014) 0.77

Cross-talk between circadian clocks, sleep-wake cycles, and metabolic networks: Dispelling the darkness. Bioessays (2016) 0.76

Circadian Oscillators: Around the Transcription-Translation Feedback Loop and on to Output. Trends Biochem Sci (2016) 0.76

Nucleosome dynamics regulate Neurospora circadian clock. EMBO Rep (2013) 0.76

CGDB: a database of circadian genes in eukaryotes. Nucleic Acids Res (2016) 0.75

Evolving roles of circadian rhythms in liver homeostasis and pathology. Oncotarget (2016) 0.75

Epigenetic alterations in the suprachiasmatic nucleus and hippocampus contribute to age-related cognitive decline. Oncotarget (2015) 0.75

Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan. Front Genet (2016) 0.75

The Circadian Clock Gene BMAL1 Coordinates Intestinal Regeneration. Cell Mol Gastroenterol Hepatol (2017) 0.75

Yin-yang actions of histone methylation regulatory complexes in the brain. Epigenomics (2016) 0.75

Robust Circadian Rhythm and Parathyroid Hormone-Induced Resetting during Hypertrophic Differentiation in ATDC5 Chondroprogenitor Cells. Acta Histochem Cytochem (2015) 0.75

Chronotherapy: Intuitive, Sound, Founded…But Not Broadly Applied. Drugs (2016) 0.75

Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway. J Biol Chem (2016) 0.75

Two sides of a coin: ecological and chronobiological perspectives of timing in the wild. Philos Trans R Soc Lond B Biol Sci (2017) 0.75

Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development. Proc Natl Acad Sci U S A (2017) 0.75

Articles cited by this

Coordinated transcription of key pathways in the mouse by the circadian clock. Cell (2002) 14.07

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab (2005) 13.91

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature (2009) 10.59

Circadian integration of metabolism and energetics. Science (2010) 6.86

Molecular analysis of mammalian circadian rhythms. Annu Rev Physiol (2001) 6.76

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell (2008) 6.44

An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science (2001) 6.07

Regulation of histone acetylation during memory formation in the hippocampus. J Biol Chem (2004) 5.99

A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science (2011) 5.91

Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. Mol Cell (2000) 5.79

The meter of metabolism. Cell (2008) 5.71

SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell (2008) 5.68

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell (2008) 5.51

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science (2009) 5.35

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science (2009) 5.30

Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cell Biol (2007) 5.24

Circadian regulator CLOCK is a histone acetyltransferase. Cell (2006) 5.24

Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions. Nat Genet (2006) 5.08

Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr Biol (2002) 4.99

CREB and memory. Annu Rev Neurosci (1998) 4.76

AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science (2009) 4.72

microRNA modulation of circadian-clock period and entrainment. Neuron (2007) 4.49

The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence. Am J Psychiatry (2005) 4.45

A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature (2010) 4.39

Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol (2010) 4.38

Rhythmic histone acetylation underlies transcription in the mammalian circadian clock. Nature (2002) 4.13

Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell (2000) 4.05

Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci U S A (2007) 3.92

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab (2012) 3.64

Crosstalk between components of circadian and metabolic cycles in mammals. Cell Metab (2011) 3.31

Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans. Nat Med (1999) 3.27

Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature (2008) 3.23

Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23

Metabolism and cancer: the circadian clock connection. Nat Rev Cancer (2009) 2.91

CLOCK-mediated acetylation of BMAL1 controls circadian function. Nature (2007) 2.65

Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock. Science (2006) 2.62

Circadian rhythms, sleep, and metabolism. J Clin Invest (2011) 2.60

Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease. Nat Rev Neurosci (2010) 2.49

Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. Science (1998) 2.38

Glucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured Rat-1 fibroblasts. J Biol Chem (2002) 2.30

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock. Science (2011) 2.28

Disruption of the diurnal rhythm of plasma melatonin in cirrhosis. Ann Intern Med (1995) 2.22

Coordination of the transcriptome and metabolome by the circadian clock. Proc Natl Acad Sci U S A (2012) 2.22

A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus. Diabetes (2001) 2.07

The human circadian metabolome. Proc Natl Acad Sci U S A (2012) 2.04

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression. Nat Struct Mol Biol (2010) 2.00

Metabolism control by the circadian clock and vice versa. Nat Struct Mol Biol (2009) 1.99

Light induces chromatin modification in cells of the mammalian circadian clock. Nat Neurosci (2000) 1.98

Circadian rhythm of redox state regulates excitability in suprachiasmatic nucleus neurons. Science (2012) 1.97

Circadian clock proteins control adaptation to novel environment and memory formation. Aging (Albany NY) (2010) 1.95

Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo. J Neurosci (2007) 1.93

Sleep and brain energy levels: ATP changes during sleep. J Neurosci (2010) 1.88

Resetting the biological clock: mediation of nocturnal circadian shifts by glutamate and NO. Science (1994) 1.88

Glucose and osmosensitive neurones of the rat hypothalamus. Nature (1969) 1.83

Histone acetyltransferase-dependent chromatin remodeling and the vascular clock. J Biol Chem (2003) 1.77

Connecting threads: epigenetics and metabolism. Cell (2012) 1.75

SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci (2010) 1.71

Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons. J Cell Sci (2003) 1.70

The polycomb group protein EZH2 is required for mammalian circadian clock function. J Biol Chem (2006) 1.67

Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior. Biol Psychiatry (2010) 1.61

miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock. Hum Mol Genet (2010) 1.53

Perinatal photoperiod imprints the circadian clock. Nat Neurosci (2010) 1.47

Melatonin membrane receptors in peripheral tissues: distribution and functions. Mol Cell Endocrinol (2012) 1.47

Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation. PLoS One (2010) 1.44

Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders. Nat Neurosci (2002) 1.43

Immunoassay of 6-hydroxymelatonin sulfate in human plasma and urine: abolition of the urinary 24-hour rhythm with atenolol. J Clin Endocrinol Metab (1985) 1.41

Plasticity and specificity of the circadian epigenome. Nat Neurosci (2010) 1.41

GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder. Neurosci Biobehav Rev (2007) 1.36

Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iepsilon (CKIepsilon)-dependent degradation of clock protein mPer2. J Biol Chem (2007) 1.35

Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. Proc Natl Acad Sci U S A (2006) 1.32

Endogenous dopamine regulates the rhythm of expression of the clock protein PER2 in the rat dorsal striatum via daily activation of D2 dopamine receptors. J Neurosci (2010) 1.28

Sweet talk in the brain: glucosensing, neural networks, and hypoglycemic counterregulation. Front Neuroendocrinol (2009) 1.25

Physiology and pharmacology of melatonin in relation to biological rhythms. Pharmacol Rep (2009) 1.21

The methamphetamine-sensitive circadian oscillator does not employ canonical clock genes. Proc Natl Acad Sci U S A (2009) 1.15

Circadian rhythms and memory formation. Nat Rev Neurosci (2010) 1.14

Circadian rhythms and mood regulation: insights from pre-clinical models. Eur Neuropsychopharmacol (2011) 1.13

Circadian control of the daily plasma glucose rhythm: an interplay of GABA and glutamate. PLoS One (2008) 1.12

Light stimulates MSK1 activation in the suprachiasmatic nucleus via a PACAP-ERK/MAP kinase-dependent mechanism. J Neurosci (2005) 1.10

Circadian rhythms of extracellular ATP accumulation in suprachiasmatic nucleus cells and cultured astrocytes. Eur J Neurosci (2009) 1.08

Hypothalamic AMP-activated protein kinase regulates glucose production. Diabetes (2010) 1.02

Circadian variation of insulin requirement in insulin dependent diabetes mellitus the relationship between circadian change in insulin demand and diurnal patterns of growth hormone, cortisol and glucagon during euglycemia. Horm Metab Res (1995) 1.01

Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s). Proc Natl Acad Sci U S A (2012) 0.99

Circadian clocks: genes, sleep, and cognition. Trends Cogn Sci (2010) 0.96

Central AMPK contributes to sleep homeostasis in mice. Neuropharmacology (2009) 0.93

Circadian rhythms and treatment implications in depression. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.92

Age differences in a circadian influence on hippocampal LTP. Brain Res (1983) 0.92

Impaired light masking in dopamine D2 receptor-null mice. Nat Neurosci (2006) 0.90

Ketamine influences CLOCK:BMAL1 function leading to altered circadian gene expression. PLoS One (2011) 0.87

Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function. PLoS One (2011) 0.86

SCN output drives the autonomic nervous system: with special reference to the autonomic function related to the regulation of glucose metabolism. Prog Brain Res (1996) 0.85

Effects of lithium on brain glucose metabolism in healthy men. J Clin Psychopharmacol (2007) 0.83

Circadian changes in long-term potentiation of rat suprachiasmatic field potentials elicited by optic nerve stimulation in vitro. Brain Res (1995) 0.82

Altered expression of circadian rhythm genes among individuals with a history of depression. J Affect Disord (2010) 0.81

Circadian rhythms and sleep--the metabolic connection. Pflugers Arch (2011) 0.79

Circadian rhythms and energy metabolism with special reference to the suprachiasmatic nucleus. Neurosci Biobehav Rev (1994) 0.78

Impaired hepatic catabolism of melatonin in cirrhosis. Ann Intern Med (1997) 0.77

Articles by these authors

(truncated to the top 100)

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell (2008) 6.44

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science (2009) 5.35

ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell (2004) 5.27

Circadian regulator CLOCK is a histone acetyltransferase. Cell (2006) 5.24

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol (2002) 4.50

A web of circadian pacemakers. Cell (2002) 4.39

Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23

Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity. Proc Natl Acad Sci U S A (2002) 3.03

Metabolism and cancer: the circadian clock connection. Nat Rev Cancer (2009) 2.91

The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components. Proc Natl Acad Sci U S A (2006) 2.75

CLOCK-mediated acetylation of BMAL1 controls circadian function. Nature (2007) 2.65

Chromatin remodelling and epigenetic features of germ cells. Nature (2005) 2.49

Circadian clock control by SUMOylation of BMAL1. Science (2005) 2.30

Coordination of the transcriptome and metabolome by the circadian clock. Proc Natl Acad Sci U S A (2012) 2.22

Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage. Cell Cycle (2006) 2.17

The chromatoid body: a germ-cell-specific RNA-processing centre. Nat Rev Mol Cell Biol (2007) 2.15

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression. Nat Struct Mol Biol (2010) 2.00

Metabolism control by the circadian clock and vice versa. Nat Struct Mol Biol (2009) 1.99

PER2 controls lipid metabolism by direct regulation of PPARγ. Cell Metab (2010) 1.91

Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis. Nat Methods (2004) 1.91

RNA granules in germ cells. Cold Spring Harb Perspect Biol (2011) 1.80

Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5. Blood (2008) 1.80

Connecting threads: epigenetics and metabolism. Cell (2012) 1.75

Phenotypic rescue of a peripheral clock genetic defect via SCN hierarchical dominance. Cell (2002) 1.71

Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons. J Cell Sci (2003) 1.70

Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance. Proc Natl Acad Sci U S A (2013) 1.64

The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1. Proc Natl Acad Sci U S A (2003) 1.64

Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis. Proc Natl Acad Sci U S A (2005) 1.59

Mammalian circadian clock and metabolism - the epigenetic link. J Cell Sci (2010) 1.55

Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells. J Cell Sci (2006) 1.52

Bindarit: an anti-inflammatory small molecule that modulates the NFκB pathway. Cell Cycle (2012) 1.51

Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD. Mol Cell (2005) 1.51

Riding tandem: circadian clocks and the cell cycle. Cell (2007) 1.49

Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM. Exp Cell Res (2002) 1.48

Metabolism and the circadian clock converge. Physiol Rev (2013) 1.47

Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation. PLoS One (2010) 1.44

Plasticity and specificity of the circadian epigenome. Nat Neurosci (2010) 1.41

Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids. Development (2002) 1.37

Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism. Mol Cell Biol (2010) 1.35

Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family. Mol Endocrinol (2002) 1.34

Chromatin remodeling, metabolism and circadian clocks: the interplay of CLOCK and SIRT1. Int J Biochem Cell Biol (2008) 1.33

Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. Proc Natl Acad Sci U S A (2006) 1.32

Regulation of metabolism: the circadian clock dictates the time. Trends Endocrinol Metab (2011) 1.32

Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor. FASEB J (2004) 1.30

The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation. J Cell Sci (2003) 1.30

Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis. Mol Endocrinol (2006) 1.30

Signaling to the circadian clock: plasticity by chromatin remodeling. Curr Opin Cell Biol (2007) 1.30

Light induction of a vertebrate clock gene involves signaling through blue-light receptors and MAP kinases. Curr Biol (2002) 1.23

CK2alpha phosphorylates BMAL1 to regulate the mammalian clock. Nat Struct Mol Biol (2009) 1.23

Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock. Proc Natl Acad Sci U S A (2010) 1.20

CREM-dependent transcription in male germ cells controlled by a kinesin. Science (2002) 1.20

Testis-specific transcription mechanisms promoting male germ-cell differentiation. Reproduction (2004) 1.16

Common pathways in circadian and cell cycle clocks: light-dependent activation of Fos/AP-1 in zebrafish controls CRY-1a and WEE-1. Proc Natl Acad Sci U S A (2005) 1.16

Circadian clock and breast cancer: a molecular link. Cell Cycle (2007) 1.14

DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation. Mol Endocrinol (2003) 1.14

Role of glucocorticoids and cAMP-mediated repression in limiting corticotropin-releasing hormone transcription during stress. J Neurosci (2005) 1.14

CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics. Nat Methods (2012) 1.14

Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis. Proc Natl Acad Sci U S A (2006) 1.13

A direct role of SRY and SOX proteins in pre-mRNA splicing. Proc Natl Acad Sci U S A (2002) 1.12

No circadian rhythms in testis: Period1 expression is clock independent and developmentally regulated in the mouse. Mol Endocrinol (2003) 1.12

Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells. BMC Genomics (2010) 1.12

Circadian control by the reduction/oxidation pathway: catalase represses light-dependent clock gene expression in the zebrafish. Proc Natl Acad Sci U S A (2007) 1.11

Structural and functional features of transcription factors controlling the circadian clock. Curr Opin Genet Dev (2005) 1.11

Mouse Period1 (mPER1) acts as a circadian adaptor to entrain the oscillator to environmental light/dark cycles by regulating mPER2 protein. J Neurosci (2005) 1.11

Circadian acetylome reveals regulation of mitochondrial metabolic pathways. Proc Natl Acad Sci U S A (2013) 1.11

Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages. Mol Pharmacol (2011) 1.07

Circadian clock regulates the host response to Salmonella. Proc Natl Acad Sci U S A (2013) 1.07

A small C-terminal sequence of Aurora B is responsible for localization and function. Mol Biol Cell (2004) 1.07

Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage. Proc Natl Acad Sci U S A (2005) 1.05

The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners. Mol Cell Biol (2005) 1.04

Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation. Dev Biol (2008) 1.03

Environmental stimulus perception and control of circadian clocks. Curr Opin Neurobiol (2002) 1.02

Temporal association of protamine 1 with the inner nuclear membrane protein lamin B receptor during spermiogenesis. J Biol Chem (2003) 1.01

Regulation of gene expression in post-meiotic male germ cells: CREM-signalling pathways and male fertility. Hum Fertil (Camb) (2006) 1.00

Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1. Proc Natl Acad Sci U S A (2013) 1.00

Light-inducible and clock-controlled expression of MAP kinase phosphatase 1 in mouse central pacemaker neurons. J Biol Rhythms (2007) 1.00

Production of fertile offspring from genetically infertile male mice. Proc Natl Acad Sci U S A (2004) 0.99

Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation. Aging (Albany NY) (2011) 0.98

Negative control of circadian clock regulator E4BP4 by casein kinase Iepsilon-mediated phosphorylation. Curr Biol (2004) 0.98

X-linked adrenal hypoplasia congenita is caused by abnormal nuclear localization of the DAX-1 protein. Proc Natl Acad Sci U S A (2002) 0.98

The circadian epigenome: how metabolism talks to chromatin remodeling. Curr Opin Cell Biol (2013) 0.98

Joining the dots: from chromatin remodeling to neuronal plasticity. Curr Opin Neurobiol (2010) 0.97

The circadian clock transcriptional complex: metabolic feedback intersects with epigenetic control. Ann N Y Acad Sci (2012) 0.96

Cycles in spatial and temporal chromosomal organization driven by the circadian clock. Nat Struct Mol Biol (2013) 0.96

The epigenetic language of circadian clocks. Handb Exp Pharmacol (2013) 0.95

Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene. Proc Natl Acad Sci U S A (2004) 0.95

Unraveling the mechanisms of the vertebrate circadian clock: zebrafish may light the way. Bioessays (2002) 0.94

SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression. Epigenetics (2012) 0.92

Time after time: inputs to and outputs from the mammalian circadian oscillators. Trends Neurosci (2002) 0.92

Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells. J Cell Sci (2012) 0.92

Common light signaling pathways controlling DNA repair and circadian clock entrainment in zebrafish. Cell Cycle (2009) 0.91

The chromatoid body of male germ cells: epigenetic control and miRNA pathway. Cell Cycle (2008) 0.91

ROS stress resets circadian clocks to coordinate pro-survival signals. PLoS One (2013) 0.91

Impaired light masking in dopamine D2 receptor-null mice. Nat Neurosci (2006) 0.90

Microtubule-independent and protein kinase A-mediated function of kinesin KIF17b controls the intracellular transport of activator of CREM in testis (ACT). J Biol Chem (2005) 0.89

Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes. Cell Mol Life Sci (2009) 0.89

Circadian clocks, epigenetics, and cancer. Curr Opin Oncol (2015) 0.89

The circadian clock and cell cycle: interconnected biological circuits. Curr Opin Cell Biol (2013) 0.89

Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1. J Biol Chem (2014) 0.89

CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver. Biochem Biophys Res Commun (2008) 0.89