Published in Hepatology on September 01, 2005
Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1. Gastroenterology (2009) 1.89
Transglutaminase 2 inhibitors and their therapeutic role in disease states. Pharmacol Ther (2007) 1.60
Transglutaminase regulation of cell function. Physiol Rev (2014) 1.28
Cellular functions of tissue transglutaminase. Int Rev Cell Mol Biol (2012) 1.27
Transglutaminase 2: a molecular Swiss army knife. Biochim Biophys Acta (2011) 1.25
TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2. Proc Natl Acad Sci U S A (2011) 0.98
Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease. J Biol Chem (2015) 0.85
Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death. Cell Death Dis (2016) 0.80
Global identification and analysis of isozyme-specific possible substrates crosslinked by transglutaminases using substrate peptides in mouse liver fibrosis. Sci Rep (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol (2005) 6.27
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
The HECT family of E3 ubiquitin ligases: multiple players in cancer development. Cancer Cell (2008) 3.35
The ubiquitin-protein ligase Itch regulates p73 stability. EMBO J (2005) 2.38
The p53 family: guardians of maternal reproduction. Nat Rev Mol Cell Biol (2011) 2.13
The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse. J Clin Invest (2003) 2.10
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev (2010) 2.06
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1. Circulation (2009) 2.05
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med (2009) 2.03
The E3 ubiquitin ligase Itch controls the protein stability of p63. Proc Natl Acad Sci U S A (2006) 2.01
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proc Natl Acad Sci U S A (2012) 1.97
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. Proc Natl Acad Sci U S A (2004) 1.91
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria. EMBO J (2005) 1.90
MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines. Cell Cycle (2011) 1.89
Tissue transglutaminase does not affect fibrotic matrix stability or regression of liver fibrosis in mice. Gastroenterology (2011) 1.85
TAp63 and DeltaNp63 in cancer and epidermal development. Cell Cycle (2007) 1.84
The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol (2008) 1.76
Dasatinib inhibits proinflammatory functions of mature human neutrophils. Blood (2012) 1.75
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc Natl Acad Sci U S A (2007) 1.70
microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Proc Natl Acad Sci U S A (2011) 1.60
Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A (2011) 1.58
Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex. EMBO J (2004) 1.58
Regulation of the apoptosis-necrosis switch. Oncogene (2004) 1.54
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates. J Neurosci (2002) 1.52
FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy. Cell Cycle (2008) 1.52
p63, a story of mice and men. J Invest Dermatol (2011) 1.50
New p63 targets in keratinocytes identified by a genome-wide approach. EMBO J (2006) 1.50
Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization. J Biol Chem (2003) 1.49
Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Proc Natl Acad Sci U S A (2003) 1.48
Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity. Cancer Res (2011) 1.47
TAp73 depletion accelerates aging through metabolic dysregulation. Genes Dev (2012) 1.45
Transglutaminase 2 in the balance of cell death and survival. FEBS Lett (2005) 1.44
Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction. Hypertension (2004) 1.44
p73 induces apoptosis by different mechanisms. Biochem Biophys Res Commun (2005) 1.42
One, two, three--p53, p63, p73 and chemosensitivity. Drug Resist Updat (2007) 1.41
p63-microRNA feedback in keratinocyte senescence. Proc Natl Acad Sci U S A (2012) 1.41
A novel recessive connexin 31 (GJB3) mutation in a case of erythrokeratodermia variabilis. J Invest Dermatol (2004) 1.39
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms. Proc Natl Acad Sci U S A (2008) 1.39
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration. Am J Pathol (2008) 1.38
p63 is upstream of IKK alpha in epidermal development. J Cell Sci (2006) 1.35
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci U S A (2009) 1.34
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A (2007) 1.34
A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome. Am J Hum Genet (2005) 1.33
PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Mol Cell Biol (2004) 1.33
p73 in Cancer. Genes Cancer (2011) 1.33
GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. Cell Cycle (2013) 1.32
Cell death and autophagy: cytokines, drugs, and nutritional factors. Toxicology (2008) 1.31
p53 is cleaved by caspases generating fragments localizing to mitochondria. J Biol Chem (2006) 1.30
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15. Genes Dev (2013) 1.30
miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro. Biochem Biophys Res Commun (2010) 1.29
Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells. J Biol Chem (2006) 1.27
5-HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants. Eur J Neurosci (2004) 1.26
p73 regulates maintenance of neural stem cell. Biochem Biophys Res Commun (2010) 1.25
Ubiquitin-dependent degradation of p73 is inhibited by PML. J Exp Med (2004) 1.24
Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice. J Exp Med (2011) 1.23
Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux. J Cell Sci (2009) 1.20
PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells. Eur J Immunol (2007) 1.19
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch. Proc Natl Acad Sci U S A (2007) 1.19
Roles for p53 and p73 during oligodendrocyte development. Development (2004) 1.18
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma. Cancer Res (2002) 1.16
Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation. Mol Pharmacol (2002) 1.16
A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis. J Biol Chem (2003) 1.14
miR-146a is modulated in human endothelial cell with aging. Atherosclerosis (2011) 1.14
E1A activates transcription of p73 and Noxa to induce apoptosis. J Biol Chem (2004) 1.14
Transglutaminase 2 is needed for the formation of an efficient phagocyte portal in macrophages engulfing apoptotic cells. J Immunol (2009) 1.13
Cardiovascular influences of alpha1b-adrenergic receptor defect in mice. Circulation (2002) 1.13
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nat Commun (2011) 1.13
p63 regulates glutaminase 2 expression. Cell Cycle (2013) 1.12
Cloning and functional characterization of carotenoid cleavage dioxygenase 4 genes. J Exp Bot (2009) 1.12
Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias. J Cell Sci (2011) 1.11
Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient. FASEB J (2002) 1.11
Transdab wiki: the interactive transglutaminase substrate database on web 2.0 surface. Amino Acids (2008) 1.10
Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states. J Pharmacol Exp Ther (2002) 1.10
Itch self-polyubiquitylation occurs through lysine-63 linkages. Biochem Pharmacol (2008) 1.09
The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway. Proc Natl Acad Sci U S A (2010) 1.09
Historical review: Negative efficacy and the constitutive activity of G-protein-coupled receptors. Trends Pharmacol Sci (2005) 1.09
p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells. Neurosci Lett (2007) 1.08
Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Proc Natl Acad Sci U S A (2010) 1.08
p73: a multifunctional protein in neurobiology. Mol Neurobiol (2011) 1.07
Identification of NCF2/p67phox as a novel p53 target gene. Cell Cycle (2012) 1.07
Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation. J Immunol (2011) 1.07
Ezrin directly interacts with the alpha1b-adrenergic receptor and plays a role in receptor recycling. J Biol Chem (2005) 1.06
Transglutaminase type II plays a protective role in hepatic injury. Am J Pathol (2003) 1.06
Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. Int J Cancer (2010) 1.05
Cell death pathology: cross-talk with autophagy and its clinical implications. Biochem Biophys Res Commun (2011) 1.04
miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. J Cell Biol (2012) 1.04
Expression of transglutaminase 5 in normal and pathologic human epidermis. J Invest Dermatol (2002) 1.04
NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2. Proc Natl Acad Sci U S A (2010) 1.03
Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein. FEBS J (2011) 1.03
Status of complementary and alternative medicine in European medical schools. Forsch Komplementmed (2006) 1.03
Lysine-specific modifications of p53: a matter of life and death? Oncotarget (2013) 1.03
The adaptor complex 2 directly interacts with the alpha 1b-adrenergic receptor and plays a role in receptor endocytosis. J Biol Chem (2003) 1.03
Cell death pathology: perspective for human diseases. Biochem Biophys Res Commun (2011) 1.03
ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages. PLoS One (2012) 1.03